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The map label for this gene is atoS [H]

Identifier: 167624442

GI number: 167624442

Start: 3040589

End: 3042355

Strand: Reverse

Name: atoS [H]

Synonym: Shal_2520

Alternate gene names: 167624442

Gene position: 3042355-3040589 (Counterclockwise)

Preceding gene: 167624445

Following gene: 167624441

Centisome position: 58.21

GC content: 45.9

Gene sequence:

>1767_bases
ATGTCGATAAAACGCTACGTGTTTATGTTATTTGGGGCGCTGATCCTACTACTGGCAATGAGTCAGTTATTTGTGGCGCA
ATATTTCAAAACCCAATTACAAGCAGAGCTTGAGCAAAGCTCAAAAAGTTTATCAAAAAGCCTCGTGAGTGTGGTGATTG
AAAATGCCGCAGAGCTTGAACGTATGGAGTTTTCATTTCCTCAGGTGCCCGAGGTTGTACCCGCTGCTGTATCAGAAGTG
CAGGCTGAATTTGAACTGGATAGCATTGATTGGGTTGAACACAATGAGCTTATAAATGAACATTTTGAAGATGAAGCTGA
TCGATTAACCGATGAGGCAGAGCAGCAGCTTGATGGCCAGCTTGAGGGCTTAAATAGTGAAATAGACCAGTTAGCACTTG
AGCTCGCCAATAGTGCGACCCAAGGCGGTGAGTTGCAGCTCAAGAGTGAGGCATTTAAGGCTAAGAAAGCTGCGCTTGAG
CAGAAGGTTCAAGCGTTATTAGCCAAAGAGCGCATGTTAGTAAAGAGTAATCGCGAGAACATGCAGCAATTGCGTGAGCA
AGCCGCACGTGAGTATCAGCAGCGGGTAGAGCGCAGCCTTGAGAATATAGAGATCCATACCGATGAATGGCTTAAAGACG
GTAGGGTGCTGATTATTGAAGGCGCTACAGCTGAGCATGCTGTTGATGGAAAAGATATGCTGGTTCACGATATCAGTAGT
AACGAAGACAGTGGCCAAAGTAACGCGCTGCAATTTAGAAGTCAGCGTACTGTCGAGCTGCCAAGTGGCGGGGCAAATCA
TCTGCTTGAGCGTTTTAGTGAGTCGGTATTATTGGCGATTTTACTAACCAGTGTGATGGCACTGCTATTGGCGTATTGGC
TAAGTCATCACGTTACCGAGCCTTTGACTGAACTTGCAGGTGGGCATAAAAAGTTGGCGGAGGGGCAGTTTGGTATACAG
CTTAAGGAGCAAGGGGTAAAAGAGCTGAAGCAGATCTTGGCTGGCTTTAACCGTATGAGTCAGGCATTAGCCAAATTAAG
TAAAAAAGAGCAGCAGATGTCGCAGCAGCAACATCTTGCCGATCTTGGGCAGATCACTCGCGGTATCGCCCATAGTCTGC
GAAACCCGCTGCATACGTTGGGGCTGCTATCAGAGCAAAGTACCTGCACCGAGTCCCTTGCTGAGCGAGAGAAACTCAAT
AGTAAGATGCAACAAAAAATCGCCTTGATGGATAAGAGTATTCAATCGTTGCTAACGCTTTCGAGCAATGAGGTGGCACG
AGACAAGGCGGTGCCGTTAAATGCCATTATTCAAGATATTTTGTTAGAGCTTTCAATAACCGGCATTAAGCCTAAAGTCA
TGTTTGACTCACAGTCTACCATCTTGCGTGTTAATGGCGCGGAGTCTGAGCTGAGAAGCATTTTACATGCAGTGATGATC
AACGCCGTTGAAGCAGATCCAGAGGCAAAGCAGATAACCATTGAGCTGAGCCAAGATGAAAAATCTAAGCGAGTAACCAT
TACTGATTGGGGCAAAGGGATAGACCCATTAGTTAAAGAGCAGATATTTAAACCCCATGTGACCACCAAAACCGAAGGCT
CTGGCATGGGGATTTATATTGCTAAGCGATTAATCGAGAGCCATTATGATGGTGAAATCCAATTTGCAGATAATCCCCAA
GGAGGCACAATCGTGACACTCATTTTTGGTCTTGGTACGCAACAGCTTGAACAACAAGCCGATATAGAACAAGGAGGTCA
CTCATGA

Upstream 100 bases:

>100_bases
TTAGGGAAAGCAGTTGGTATCAATCTTGTATAGTGATATGAGAATAGAGTGATATGACCGCAGCCTGAACGTGTAGATAG
GGAAATTAAAAGAGTAGATT

Downstream 100 bases:

>100_bases
GTCATGCCCCCCTACAGATCTTAGTCGTTGAAGATGAACCGGATCAACGCGAGCTTATCTGCCAAATTTTAGCTGCAAAT
GAATATCAGATCCGCAGCGC

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 588; Mature: 587

Protein sequence:

>588_residues
MSIKRYVFMLFGALILLLAMSQLFVAQYFKTQLQAELEQSSKSLSKSLVSVVIENAAELERMEFSFPQVPEVVPAAVSEV
QAEFELDSIDWVEHNELINEHFEDEADRLTDEAEQQLDGQLEGLNSEIDQLALELANSATQGGELQLKSEAFKAKKAALE
QKVQALLAKERMLVKSNRENMQQLREQAAREYQQRVERSLENIEIHTDEWLKDGRVLIIEGATAEHAVDGKDMLVHDISS
NEDSGQSNALQFRSQRTVELPSGGANHLLERFSESVLLAILLTSVMALLLAYWLSHHVTEPLTELAGGHKKLAEGQFGIQ
LKEQGVKELKQILAGFNRMSQALAKLSKKEQQMSQQQHLADLGQITRGIAHSLRNPLHTLGLLSEQSTCTESLAEREKLN
SKMQQKIALMDKSIQSLLTLSSNEVARDKAVPLNAIIQDILLELSITGIKPKVMFDSQSTILRVNGAESELRSILHAVMI
NAVEADPEAKQITIELSQDEKSKRVTITDWGKGIDPLVKEQIFKPHVTTKTEGSGMGIYIAKRLIESHYDGEIQFADNPQ
GGTIVTLIFGLGTQQLEQQADIEQGGHS

Sequences:

>Translated_588_residues
MSIKRYVFMLFGALILLLAMSQLFVAQYFKTQLQAELEQSSKSLSKSLVSVVIENAAELERMEFSFPQVPEVVPAAVSEV
QAEFELDSIDWVEHNELINEHFEDEADRLTDEAEQQLDGQLEGLNSEIDQLALELANSATQGGELQLKSEAFKAKKAALE
QKVQALLAKERMLVKSNRENMQQLREQAAREYQQRVERSLENIEIHTDEWLKDGRVLIIEGATAEHAVDGKDMLVHDISS
NEDSGQSNALQFRSQRTVELPSGGANHLLERFSESVLLAILLTSVMALLLAYWLSHHVTEPLTELAGGHKKLAEGQFGIQ
LKEQGVKELKQILAGFNRMSQALAKLSKKEQQMSQQQHLADLGQITRGIAHSLRNPLHTLGLLSEQSTCTESLAEREKLN
SKMQQKIALMDKSIQSLLTLSSNEVARDKAVPLNAIIQDILLELSITGIKPKVMFDSQSTILRVNGAESELRSILHAVMI
NAVEADPEAKQITIELSQDEKSKRVTITDWGKGIDPLVKEQIFKPHVTTKTEGSGMGIYIAKRLIESHYDGEIQFADNPQ
GGTIVTLIFGLGTQQLEQQADIEQGGHS
>Mature_587_residues
SIKRYVFMLFGALILLLAMSQLFVAQYFKTQLQAELEQSSKSLSKSLVSVVIENAAELERMEFSFPQVPEVVPAAVSEVQ
AEFELDSIDWVEHNELINEHFEDEADRLTDEAEQQLDGQLEGLNSEIDQLALELANSATQGGELQLKSEAFKAKKAALEQ
KVQALLAKERMLVKSNRENMQQLREQAAREYQQRVERSLENIEIHTDEWLKDGRVLIIEGATAEHAVDGKDMLVHDISSN
EDSGQSNALQFRSQRTVELPSGGANHLLERFSESVLLAILLTSVMALLLAYWLSHHVTEPLTELAGGHKKLAEGQFGIQL
KEQGVKELKQILAGFNRMSQALAKLSKKEQQMSQQQHLADLGQITRGIAHSLRNPLHTLGLLSEQSTCTESLAEREKLNS
KMQQKIALMDKSIQSLLTLSSNEVARDKAVPLNAIIQDILLELSITGIKPKVMFDSQSTILRVNGAESELRSILHAVMIN
AVEADPEAKQITIELSQDEKSKRVTITDWGKGIDPLVKEQIFKPHVTTKTEGSGMGIYIAKRLIESHYDGEIQFADNPQG
GTIVTLIFGLGTQQLEQQADIEQGGHS

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=234, Percent_Identity=32.4786324786325, Blast_Score=105, Evalue=9e-24,
Organism=Escherichia coli, GI1790436, Length=221, Percent_Identity=27.1493212669683, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1790346, Length=257, Percent_Identity=27.2373540856031, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 65440; Mature: 65309

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIKRYVFMLFGALILLLAMSQLFVAQYFKTQLQAELEQSSKSLSKSLVSVVIENAAELE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RMEFSFPQVPEVVPAAVSEVQAEFELDSIDWVEHNELINEHFEDEADRLTDEAEQQLDGQ
HHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
LEGLNSEIDQLALELANSATQGGELQLKSEAFKAKKAALEQKVQALLAKERMLVKSNREN
HHCCHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
MQQLREQAAREYQQRVERSLENIEIHTDEWLKDGRVLIIEGATAEHAVDGKDMLVHDISS
HHHHHHHHHHHHHHHHHHHHHHCEECCHHHHCCCCEEEEECCCHHHCCCCCHHEEEECCC
NEDSGQSNALQFRSQRTVELPSGGANHLLERFSESVLLAILLTSVMALLLAYWLSHHVTE
CCCCCCHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLTELAGGHKKLAEGQFGIQLKEQGVKELKQILAGFNRMSQALAKLSKKEQQMSQQQHLA
HHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLGQITRGIAHSLRNPLHTLGLLSEQSTCTESLAEREKLNSKMQQKIALMDKSIQSLLTL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSNEVARDKAVPLNAIIQDILLELSITGIKPKVMFDSQSTILRVNGAESELRSILHAVMI
CCCHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEECCCHHHHHHHHHHHHH
NAVEADPEAKQITIELSQDEKSKRVTITDWGKGIDPLVKEQIFKPHVTTKTEGSGMGIYI
HHHCCCCCCEEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHH
AKRLIESHYDGEIQFADNPQGGTIVTLIFGLGTQQLEQQADIEQGGHS
HHHHHHHCCCCEEEECCCCCCCEEEEHHHHCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SIKRYVFMLFGALILLLAMSQLFVAQYFKTQLQAELEQSSKSLSKSLVSVVIENAAELE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RMEFSFPQVPEVVPAAVSEVQAEFELDSIDWVEHNELINEHFEDEADRLTDEAEQQLDGQ
HHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
LEGLNSEIDQLALELANSATQGGELQLKSEAFKAKKAALEQKVQALLAKERMLVKSNREN
HHCCHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
MQQLREQAAREYQQRVERSLENIEIHTDEWLKDGRVLIIEGATAEHAVDGKDMLVHDISS
HHHHHHHHHHHHHHHHHHHHHHCEECCHHHHCCCCEEEEECCCHHHCCCCCHHEEEECCC
NEDSGQSNALQFRSQRTVELPSGGANHLLERFSESVLLAILLTSVMALLLAYWLSHHVTE
CCCCCCHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLTELAGGHKKLAEGQFGIQLKEQGVKELKQILAGFNRMSQALAKLSKKEQQMSQQQHLA
HHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLGQITRGIAHSLRNPLHTLGLLSEQSTCTESLAEREKLNSKMQQKIALMDKSIQSLLTL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSNEVARDKAVPLNAIIQDILLELSITGIKPKVMFDSQSTILRVNGAESELRSILHAVMI
CCCHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEECCCHHHHHHHHHHHHH
NAVEADPEAKQITIELSQDEKSKRVTITDWGKGIDPLVKEQIFKPHVTTKTEGSGMGIYI
HHHCCCCCCEEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHH
AKRLIESHYDGEIQFADNPQGGTIVTLIFGLGTQQLEQQADIEQGGHS
HHHHHHHCCCCEEEECCCCCCCEEEEHHHHCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]