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The map label for this gene is sucC [H]

Identifier: 167624409

GI number: 167624409

Start: 2989288

End: 2990454

Strand: Reverse

Name: sucC [H]

Synonym: Shal_2487

Alternate gene names: 167624409

Gene position: 2990454-2989288 (Counterclockwise)

Preceding gene: 167624410

Following gene: 167624408

Centisome position: 57.21

GC content: 46.7

Gene sequence:

>1167_bases
ATGAATTTGCACGAATATCAGGCAAAAGCGTTATTTGCCGAATATGGCTTGCCAGTGTCAGAAGGTTTTGCATGCGATAC
GGCTCAAGAAGCTGTAGAAGCTGCTGGTCATATTGGCGGAGATATGTGGGTTGTTAAGTGTCAAGTACACGCAGGTGGCC
GTGGTAAAGCGGGCGGCGTTAAAGTCACTGGCGATAAAGAAGAGATCCGAGCCTTCGCTGAACACTGGTTAGGTAAGAAC
TTAGTGACTTATCAGACTGATGAGAAAGGCCAGCCAGTTGCTAAAATCTTAGTTGAAAGCTGTACTGACATCGCAAACGA
GCTTTATTTAGGTGCGGTTGTTGACCGTGCAACTCGTCGCGTTGTATTTATGGCATCGACTGAAGGCGGTGTTGAGATTG
AAACTGTGGCTGAAGAAACGCCAGAGTTGATCCACAAGGCTATCATCGATCCACTTACAGGCCCTCAGCCATATCAAGCA
CGCGATCTTGGCTTCAAGCTAGGTCTAAATCCAACTCAGATGAAACAGTTCACTAAAGTCTTTATGGGCTTAGCGAAAAT
GTTTGAAGACCATGATTTCGCACTGCTTGAAATCAACCCACTTGTTATCACAGACGAAGGCAACATTCACTGTCTCGATG
GCAAGATTGGTATCGACGGCAACGCACTGTTCCGTCAGCCTAAAATTCGTGACATGCACGATCCATCACAAGATGATGCT
CGTGAAGCACACGCGGCTAAGTTCGAGCTTAACTATGTTGCACTCGACGGAAACGTGGGTTGCATGGTTAATGGCGCGGG
CCTAGCAATGGGTACCATGGATATTGTAAATCTACACGGGGGCAAGCCTGCTAACTTCCTTGACGTTGGTGGTGGCGCAA
CTAAAGAGCGTGTAGCTGAAGCATTTAAGATCATCTTGTCTGATTCCAATGTTAAGGCGGTTCTTGTTAACATCTTTGGT
GGTATCGTTCGTTGTGACATGATTGCTGAAGGCATCATTGGCGCAGTTAAAGAGGTCGGTGTTGAAGTACCTGTTGTTGT
TCGTCTTGAAGGTACTAACGCTAATCTAGGTCGCGATGTATTGGCAAGCTCAGGCCTTGACATTATTGCTGCTGAATCAC
TAACAGATGCTGCTGTTAAAGTTGTTGCTGCTGCGGAGGGCAAATAA

Upstream 100 bases:

>100_bases
TCGTCTGCTTCTTGACCTATAAGTCAAGACAGACAATACCCTAGCTGCAGGCCCGTTTGGGCCTGCTGAAATACATAAGA
AGTAGAATGGATAGATCATC

Downstream 100 bases:

>100_bases
TGTCTGTATTAATTAACAAAGATACCAAGGTTATCTGTCAGGGTTTCACTGGCGGTCAAGGCACATTCCACTCTGAGCAA
GCTATCGCTTATGGTACTCA

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MNLHEYQAKALFAEYGLPVSEGFACDTAQEAVEAAGHIGGDMWVVKCQVHAGGRGKAGGVKVTGDKEEIRAFAEHWLGKN
LVTYQTDEKGQPVAKILVESCTDIANELYLGAVVDRATRRVVFMASTEGGVEIETVAEETPELIHKAIIDPLTGPQPYQA
RDLGFKLGLNPTQMKQFTKVFMGLAKMFEDHDFALLEINPLVITDEGNIHCLDGKIGIDGNALFRQPKIRDMHDPSQDDA
REAHAAKFELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAEAFKIILSDSNVKAVLVNIFG
GIVRCDMIAEGIIGAVKEVGVEVPVVVRLEGTNANLGRDVLASSGLDIIAAESLTDAAVKVVAAAEGK

Sequences:

>Translated_388_residues
MNLHEYQAKALFAEYGLPVSEGFACDTAQEAVEAAGHIGGDMWVVKCQVHAGGRGKAGGVKVTGDKEEIRAFAEHWLGKN
LVTYQTDEKGQPVAKILVESCTDIANELYLGAVVDRATRRVVFMASTEGGVEIETVAEETPELIHKAIIDPLTGPQPYQA
RDLGFKLGLNPTQMKQFTKVFMGLAKMFEDHDFALLEINPLVITDEGNIHCLDGKIGIDGNALFRQPKIRDMHDPSQDDA
REAHAAKFELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAEAFKIILSDSNVKAVLVNIFG
GIVRCDMIAEGIIGAVKEVGVEVPVVVRLEGTNANLGRDVLASSGLDIIAAESLTDAAVKVVAAAEGK
>Mature_388_residues
MNLHEYQAKALFAEYGLPVSEGFACDTAQEAVEAAGHIGGDMWVVKCQVHAGGRGKAGGVKVTGDKEEIRAFAEHWLGKN
LVTYQTDEKGQPVAKILVESCTDIANELYLGAVVDRATRRVVFMASTEGGVEIETVAEETPELIHKAIIDPLTGPQPYQA
RDLGFKLGLNPTQMKQFTKVFMGLAKMFEDHDFALLEINPLVITDEGNIHCLDGKIGIDGNALFRQPKIRDMHDPSQDDA
REAHAAKFELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAEAFKIILSDSNVKAVLVNIFG
GIVRCDMIAEGIIGAVKEVGVEVPVVVRLEGTNANLGRDVLASSGLDIIAAESLTDAAVKVVAAAEGK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=393, Percent_Identity=45.5470737913486, Blast_Score=335, Evalue=4e-92,
Organism=Homo sapiens, GI157779135, Length=387, Percent_Identity=44.9612403100775, Blast_Score=312, Evalue=4e-85,
Organism=Homo sapiens, GI294862256, Length=363, Percent_Identity=45.4545454545455, Blast_Score=298, Evalue=6e-81,
Organism=Escherichia coli, GI1786948, Length=388, Percent_Identity=76.2886597938144, Blast_Score=583, Evalue=1e-168,
Organism=Caenorhabditis elegans, GI17567829, Length=388, Percent_Identity=43.5567010309278, Blast_Score=311, Evalue=5e-85,
Organism=Caenorhabditis elegans, GI17539378, Length=400, Percent_Identity=41.75, Blast_Score=302, Evalue=2e-82,
Organism=Saccharomyces cerevisiae, GI6321683, Length=392, Percent_Identity=43.3673469387755, Blast_Score=327, Evalue=1e-90,
Organism=Drosophila melanogaster, GI21356231, Length=397, Percent_Identity=43.8287153652393, Blast_Score=307, Evalue=9e-84,
Organism=Drosophila melanogaster, GI161078106, Length=385, Percent_Identity=42.8571428571429, Blast_Score=290, Evalue=1e-78,
Organism=Drosophila melanogaster, GI24645208, Length=385, Percent_Identity=42.8571428571429, Blast_Score=290, Evalue=1e-78,
Organism=Drosophila melanogaster, GI281361397, Length=386, Percent_Identity=43.0051813471503, Blast_Score=288, Evalue=6e-78,
Organism=Drosophila melanogaster, GI281361395, Length=386, Percent_Identity=43.0051813471503, Blast_Score=288, Evalue=6e-78,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 41309; Mature: 41309

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHEYQAKALFAEYGLPVSEGFACDTAQEAVEAAGHIGGDMWVVKCQVHAGGRGKAGGV
CCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCE
KVTGDKEEIRAFAEHWLGKNLVTYQTDEKGQPVAKILVESCTDIANELYLGAVVDRATRR
EEECCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
VVFMASTEGGVEIETVAEETPELIHKAIIDPLTGPQPYQARDLGFKLGLNPTQMKQFTKV
EEEEEECCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCHHCCCEEECCCHHHHHHHHHH
FMGLAKMFEDHDFALLEINPLVITDEGNIHCLDGKIGIDGNALFRQPKIRDMHDPSQDDA
HHHHHHHHCCCCEEEEEEEEEEEECCCCEEEECCEEECCCCCEECCCCCCCCCCCCCHHH
REAHAAKFELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAE
HHHHHEEEEEEEEEECCCCEEEEECCCEEECCEEEEEECCCCCCCEEECCCCCCHHHHHH
AFKIILSDSNVKAVLVNIFGGIVRCDMIAEGIIGAVKEVGVEVPVVVRLEGTNANLGRDV
HHHHEECCCCCEEEHEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHH
LASSGLDIIAAESLTDAAVKVVAAAEGK
HHCCCCCEEEECHHHHHHEEEEEECCCC
>Mature Secondary Structure
MNLHEYQAKALFAEYGLPVSEGFACDTAQEAVEAAGHIGGDMWVVKCQVHAGGRGKAGGV
CCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCE
KVTGDKEEIRAFAEHWLGKNLVTYQTDEKGQPVAKILVESCTDIANELYLGAVVDRATRR
EEECCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
VVFMASTEGGVEIETVAEETPELIHKAIIDPLTGPQPYQARDLGFKLGLNPTQMKQFTKV
EEEEEECCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCHHCCCEEECCCHHHHHHHHHH
FMGLAKMFEDHDFALLEINPLVITDEGNIHCLDGKIGIDGNALFRQPKIRDMHDPSQDDA
HHHHHHHHCCCCEEEEEEEEEEEECCCCEEEECCEEECCCCCEECCCCCCCCCCCCCHHH
REAHAAKFELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAE
HHHHHEEEEEEEEEECCCCEEEEECCCEEECCEEEEEECCCCCCCEEECCCCCCHHHHHH
AFKIILSDSNVKAVLVNIFGGIVRCDMIAEGIIGAVKEVGVEVPVVVRLEGTNANLGRDV
HHHHEECCCCCEEEHEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHH
LASSGLDIIAAESLTDAAVKVVAAAEGK
HHCCCCCEEEECHHHHHHEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA