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The map label for this gene is bioD [H]

Identifier: 167624396

GI number: 167624396

Start: 2975564

End: 2976229

Strand: Reverse

Name: bioD [H]

Synonym: Shal_2474

Alternate gene names: 167624396

Gene position: 2976229-2975564 (Counterclockwise)

Preceding gene: 167624397

Following gene: 167624395

Centisome position: 56.94

GC content: 46.1

Gene sequence:

>666_bases
ATGACATTTTTTGTAACGGGTACAGATACCGATTGTGGTAAGACGTTGATCTCATCTGCATTGCTAACTGCCGCTAACGG
CGAAACCGTAGGTTTTAAACCGATTGCTTCTGGCTGCGAACAAACAGACAAAGGGCTTCGTAATAGTGATGCATTGGCGT
TAATGGCTGCCTCGAGTATTAAACTACCTTACGAGGATATTAATCCTTTTGCCTTTGAAGCTGCGATTGCGCCGCACATC
GCAGCCGCAGAGAAAGGCGTTCAATTAGCGCCTAAGCGTATCGAAGCGCTGCTCAAGATGTCAGAGTATGTGGGTGCTGA
TTTTTGCTTGATTGAAGGTGCTGGAGGATGGCGCTTACCATTAGGAGAAGGGCACTTCCTTTCTGAGGTTGTACAATCAA
TGAACTTACCCGTGATCTTAGTGGTGGGGATGAAATTAGGCTGTTTAAATCACGCATTATTAACGGCCGAAGCGATTAAG
GCTGACGGTTTGAATCTTGTTGGCTGGGTGGCGAATCAAGTTGACCCTGACATGGCTAATCAAGAGGAAAACCTCGCCGC
GCTAAAAGAGATGATGTCGGCACCTTGCTTAGGTTATGTTCCATATTTAACAAACCCAACTGCTGAACATGCTGCGAGTC
ACCTAGAGCTTAGTGTTTTGCTATAA

Upstream 100 bases:

>100_bases
TCAGGCAGAGTTGAGTCGAGCCCCTGAGGGCCTTCCTTTAACTTATAATATTAGCTTTATTAAAGCGCGAAAAAAGCGCT
AGTCGCAGCTTGGAGTTGAC

Downstream 100 bases:

>100_bases
GCTAACCCAATAGCAAATATGTAAAAGCTTGTTCGCAAAATTAAAGCCCAATCTGGGGAGGTATGATGCTCTCTGAATTG
GGCTTATCTTTCTGTTAACA

Product: dethiobiotin synthase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MTFFVTGTDTDCGKTLISSALLTAANGETVGFKPIASGCEQTDKGLRNSDALALMAASSIKLPYEDINPFAFEAAIAPHI
AAAEKGVQLAPKRIEALLKMSEYVGADFCLIEGAGGWRLPLGEGHFLSEVVQSMNLPVILVVGMKLGCLNHALLTAEAIK
ADGLNLVGWVANQVDPDMANQEENLAALKEMMSAPCLGYVPYLTNPTAEHAASHLELSVLL

Sequences:

>Translated_221_residues
MTFFVTGTDTDCGKTLISSALLTAANGETVGFKPIASGCEQTDKGLRNSDALALMAASSIKLPYEDINPFAFEAAIAPHI
AAAEKGVQLAPKRIEALLKMSEYVGADFCLIEGAGGWRLPLGEGHFLSEVVQSMNLPVILVVGMKLGCLNHALLTAEAIK
ADGLNLVGWVANQVDPDMANQEENLAALKEMMSAPCLGYVPYLTNPTAEHAASHLELSVLL
>Mature_220_residues
TFFVTGTDTDCGKTLISSALLTAANGETVGFKPIASGCEQTDKGLRNSDALALMAASSIKLPYEDINPFAFEAAIAPHIA
AAEKGVQLAPKRIEALLKMSEYVGADFCLIEGAGGWRLPLGEGHFLSEVVQSMNLPVILVVGMKLGCLNHALLTAEAIKA
DGLNLVGWVANQVDPDMANQEENLAALKEMMSAPCLGYVPYLTNPTAEHAASHLELSVLL

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=222, Percent_Identity=46.8468468468468, Blast_Score=196, Evalue=1e-51,
Organism=Escherichia coli, GI87081944, Length=224, Percent_Identity=42.4107142857143, Blast_Score=174, Evalue=5e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 23328; Mature: 23197

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFFVTGTDTDCGKTLISSALLTAANGETVGFKPIASGCEQTDKGLRNSDALALMAASSI
CEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCC
KLPYEDINPFAFEAAIAPHIAAAEKGVQLAPKRIEALLKMSEYVGADFCLIEGAGGWRLP
CCCHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCEECC
LGEGHFLSEVVQSMNLPVILVVGMKLGCLNHALLTAEAIKADGLNLVGWVANQVDPDMAN
CCCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEHHHHCCCCCCCC
QEENLAALKEMMSAPCLGYVPYLTNPTAEHAASHLELSVLL
CHHHHHHHHHHHCCCCCEECCCCCCCCHHHHHHHCEEEEEC
>Mature Secondary Structure 
TFFVTGTDTDCGKTLISSALLTAANGETVGFKPIASGCEQTDKGLRNSDALALMAASSI
EEEEECCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCC
KLPYEDINPFAFEAAIAPHIAAAEKGVQLAPKRIEALLKMSEYVGADFCLIEGAGGWRLP
CCCHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCEECC
LGEGHFLSEVVQSMNLPVILVVGMKLGCLNHALLTAEAIKADGLNLVGWVANQVDPDMAN
CCCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEHHHHCCCCCCCC
QEENLAALKEMMSAPCLGYVPYLTNPTAEHAASHLELSVLL
CHHHHHHHHHHHCCCCCEECCCCCCCCHHHHHHHCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA