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The map label for this gene is bioC [H]

Identifier: 167624397

GI number: 167624397

Start: 2976248

End: 2977018

Strand: Reverse

Name: bioC [H]

Synonym: Shal_2475

Alternate gene names: 167624397

Gene position: 2977018-2976248 (Counterclockwise)

Preceding gene: 167624398

Following gene: 167624396

Centisome position: 56.96

GC content: 45.01

Gene sequence:

>771_bases
GTGAATACAGGATCAAGTAAACTTAATCACCAAGTTGCAGCGTGCTTCTCTGCCGCCGCAGCACATTACCATAGCTATGA
TGTACTGCAAAAACGAACCGCAGAGCATCTATTAGCTCAAGTGACATCAAGTACGCGCTTATTAGACATAGGTGCAGGTC
CAGGTACTTGTTTTGCACATATCCCGGCCATTGAACAAGTTTTCAGCTTAGATATTGCCGATGGTATGCTTAAAACACTT
AGCGAAAACTTCCCGCAGTACATTCCGATTTGTGGCGATGCGCAGAGCCTTCCTTTCGCTGCAGGCACTATCGATGGCAT
CTATTCCAATGTTGCGTTGCAATGGTGTCAAGACCTTCCTCTAGCAGTGAGTGAAGCTTGCAGAGTGCTCAAGTATGGCG
GCGAGCTCAATATGAGTATCGTGGCTGAAAATAGTCTGCATCAGTTGGCTGAACTTGGGCTCAAGGTGAATACATTTATC
GATGAAAAGTCACTGCTTGCTTGTTTTGAGCAAGATACTTGGCTGATAGAGGTATTTGAAACACAAGCGGTAACCGTTAA
TTTTGTAGATCTCAGAGCCATGCTGCAGTCAATTAAAGGCGTGGGAGCATCAATAGTGAAACGAGAACAAGATGTTAACT
TGCCTCAGGTCACATTGAGAGGACGTAAAGATTGGCAAGCTTTGCAAGCTCAGGCAGAGTTGAGTCGAGCCCCTGAGGGC
CTTCCTTTAACTTATAATATTAGCTTTATTAAAGCGCGAAAAAAGCGCTAG

Upstream 100 bases:

>100_bases
AAGATTGACCTTAAATGCTAATCACTGCCAGCAAGATATTCTGGCGTTAGTGGATGTGTTGGCCGCTATCTTAAATGATG
AATGATTAGGATCCAATGCA

Downstream 100 bases:

>100_bases
TCGCAGCTTGGAGTTGACATGACATTTTTTGTAACGGGTACAGATACCGATTGTGGTAAGACGTTGATCTCATCTGCATT
GCTAACTGCCGCTAACGGCG

Product: type 11 methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MNTGSSKLNHQVAACFSAAAAHYHSYDVLQKRTAEHLLAQVTSSTRLLDIGAGPGTCFAHIPAIEQVFSLDIADGMLKTL
SENFPQYIPICGDAQSLPFAAGTIDGIYSNVALQWCQDLPLAVSEACRVLKYGGELNMSIVAENSLHQLAELGLKVNTFI
DEKSLLACFEQDTWLIEVFETQAVTVNFVDLRAMLQSIKGVGASIVKREQDVNLPQVTLRGRKDWQALQAQAELSRAPEG
LPLTYNISFIKARKKR

Sequences:

>Translated_256_residues
MNTGSSKLNHQVAACFSAAAAHYHSYDVLQKRTAEHLLAQVTSSTRLLDIGAGPGTCFAHIPAIEQVFSLDIADGMLKTL
SENFPQYIPICGDAQSLPFAAGTIDGIYSNVALQWCQDLPLAVSEACRVLKYGGELNMSIVAENSLHQLAELGLKVNTFI
DEKSLLACFEQDTWLIEVFETQAVTVNFVDLRAMLQSIKGVGASIVKREQDVNLPQVTLRGRKDWQALQAQAELSRAPEG
LPLTYNISFIKARKKR
>Mature_256_residues
MNTGSSKLNHQVAACFSAAAAHYHSYDVLQKRTAEHLLAQVTSSTRLLDIGAGPGTCFAHIPAIEQVFSLDIADGMLKTL
SENFPQYIPICGDAQSLPFAAGTIDGIYSNVALQWCQDLPLAVSEACRVLKYGGELNMSIVAENSLHQLAELGLKVNTFI
DEKSLLACFEQDTWLIEVFETQAVTVNFVDLRAMLQSIKGVGASIVKREQDVNLPQVTLRGRKDWQALQAQAELSRAPEG
LPLTYNISFIKARKKR

Specific function: BioC is involved in an early, but chemically unexplored, step in the conversion of pimelic acid to biotin [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

Organism=Escherichia coli, GI1786994, Length=232, Percent_Identity=29.3103448275862, Blast_Score=84, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011814
- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: NA

Molecular weight: Translated: 28052; Mature: 28052

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTGSSKLNHQVAACFSAAAAHYHSYDVLQKRTAEHLLAQVTSSTRLLDIGAGPGTCFAH
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEH
IPAIEQVFSLDIADGMLKTLSENFPQYIPICGDAQSLPFAAGTIDGIYSNVALQWCQDLP
HHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
LAVSEACRVLKYGGELNMSIVAENSLHQLAELGLKVNTFIDEKSLLACFEQDTWLIEVFE
HHHHHHHHHHHCCCCCEEEEEECHHHHHHHHCCCHHHHHHCHHHHHHHHCCCCEEEEEEE
TQAVTVNFVDLRAMLQSIKGVGASIVKREQDVNLPQVTLRGRKDWQALQAQAELSRAPEG
CCEEEEEHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHCCCC
LPLTYNISFIKARKKR
CEEEEEEHEEEECCCC
>Mature Secondary Structure
MNTGSSKLNHQVAACFSAAAAHYHSYDVLQKRTAEHLLAQVTSSTRLLDIGAGPGTCFAH
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEH
IPAIEQVFSLDIADGMLKTLSENFPQYIPICGDAQSLPFAAGTIDGIYSNVALQWCQDLP
HHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
LAVSEACRVLKYGGELNMSIVAENSLHQLAELGLKVNTFIDEKSLLACFEQDTWLIEVFE
HHHHHHHHHHHCCCCCEEEEEECHHHHHHHHCCCHHHHHHCHHHHHHHHCCCCEEEEEEE
TQAVTVNFVDLRAMLQSIKGVGASIVKREQDVNLPQVTLRGRKDWQALQAQAELSRAPEG
CCEEEEEHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHCCCC
LPLTYNISFIKARKKR
CEEEEEEHEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8250549 [H]