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The map label for this gene is aer [H]

Identifier: 167624351

GI number: 167624351

Start: 2930653

End: 2932227

Strand: Reverse

Name: aer [H]

Synonym: Shal_2428

Alternate gene names: 167624351

Gene position: 2932227-2930653 (Counterclockwise)

Preceding gene: 167624352

Following gene: 167624346

Centisome position: 56.1

GC content: 47.56

Gene sequence:

>1575_bases
ATGCGAAATAACCAACCGGTCACGCAAACAGAAAAAACATTAACTGACAATTGCATATTACTGTCGACGACGGACCTTAA
CGGTAATATTAAGTATGCAAATGAAGGCTTCATCAATGTGAGTGGCTACAGTTTTGATGAGTTGCATAGACAGCCTCACA
ATCTGGTGCGTCACCCCGATATGCCGGAGGCGGCTTTCGAGTCGCTTTGGTCGCGTATTAAAACAGGTAAGCCTTGGGTG
GGGATTGTTAAGAATCGCAGTAAAAATGGCGACCACTACTGGGTCAATGCCTATGTGGCACCCGTCTTTGAAAACGGTAA
AATCCACGAGTATCAATCGGTACGCCGTAAGGCCACGCCGGAGCAAATCAATCGAGCCCAAGGCATCTATCAAGCTATTC
AAAAGGGGAAGCAGCCCAAGGCTATACGCAAACCTTTATTGGGCTTTAGCGCTAAGCTGTATGTTTGGCTGATGTTAACC
GTAGTTATCGCTGCGGGGCTATCAAGTTACTCCCCCATAGCTGCGGCCATTCTAGCCACAGTGGTTGGTATCGCGGGGTT
AAGTGTTATTTTAAAGCCGTTTAATACTCTAGTGTCTCAGGCTAGAAATACCATTGATGATCCTTTAGCCGCGGGCGTAT
TTACGGGTCGACAAGATGAAATTGGCAAAATTGGTTTTGCTCTACAGTTTTTACTGACCGAAACCGGAGGCGTAGTGGGC
AGGATGGCGGATTCTGCAGGCTCAATTGAATCCCTTAGCGCCAGCTTAAACGCTACCATAGCGAACACTCGTCAGCGTGC
CGATAGCCAAAGCATGCAGACTAGCCAAGCGGCAACTGCAATGGAAGAGATGAGTGCCAGCTTTAATGAGGTGAGTCAAA
ATATTCATAGCGCTGCACGGGAAATGTCAGTCAGTAATCTTTCGGCAGAAAAGGGCCATGAGTTGCTGGTGCGGGTTATT
GAGTCTATCAATCAGCTTAAAGATGAGGTGGGCAACTTTGCATCAGTAGTCGCATCGATTGAGCAAGATAGCCAAGACAT
TAATAATGTATTGGATGTTATTCGTGGTATCGCCGAGCAGACGAATCTGTTGGCATTAAACGCGGCTATTGAGGCCGCAA
GAGCTGGCGAGTCAGGACGAGGCTTTGCTGTCGTGGCCGATGAAGTACGTCAACTTTCAAGTCGTACCAGTGAATCGACT
TCGCATATTGAAGCTATCGTCAGTAAGTTTAGAGAAAGCACCGAAAGGGCGGCTAAAACTATGGCTGCGGGTCAGCGTAA
GGCGGAGCAATCTGTTGACTTAGCCAAGCAGGTAGATGAATCTTTTGAAGCGCTCAGAGAGTCCATTATAAGAATGAATT
CGATGAGTGATGAAAACGCCTGCGCTATGACTCAGCAAACCACGGTTGCAAATGATATTAGCCACTCTATTCAGGTGATC
AGTGAGTTGTCGCTAGAGAGCTTGGAGCAAACGCTGGATGCATCACAGCGAGGCGAGCAGGTGTCGCGTTTATCGACCAA
GACCCACAATTTATCAAGACAGTTCTGGGAACAGAGCGTACAGAGAAAGGTTTAG

Upstream 100 bases:

>100_bases
ATCATGAGCAGAATGTCGTTTGTTGATAGCAATCAATGATTTCATTATCTGATCTTGTCAGAATCGCTGCTATCTTGTTT
AAGCAATAAGACTAATAACA

Downstream 100 bases:

>100_bases
TTTTCGTCACAAAGTGGATAAACGAGAAACGCAGTTTAGTTAAACTGCGTTTTTTTATGGGGCATTGTGAAAGAAGGTCC
TAGGAAAAGCAGGTTCTAGA

Product: Pas/Pac sensor containing methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 524; Mature: 524

Protein sequence:

>524_residues
MRNNQPVTQTEKTLTDNCILLSTTDLNGNIKYANEGFINVSGYSFDELHRQPHNLVRHPDMPEAAFESLWSRIKTGKPWV
GIVKNRSKNGDHYWVNAYVAPVFENGKIHEYQSVRRKATPEQINRAQGIYQAIQKGKQPKAIRKPLLGFSAKLYVWLMLT
VVIAAGLSSYSPIAAAILATVVGIAGLSVILKPFNTLVSQARNTIDDPLAAGVFTGRQDEIGKIGFALQFLLTETGGVVG
RMADSAGSIESLSASLNATIANTRQRADSQSMQTSQAATAMEEMSASFNEVSQNIHSAAREMSVSNLSAEKGHELLVRVI
ESINQLKDEVGNFASVVASIEQDSQDINNVLDVIRGIAEQTNLLALNAAIEAARAGESGRGFAVVADEVRQLSSRTSEST
SHIEAIVSKFRESTERAAKTMAAGQRKAEQSVDLAKQVDESFEALRESIIRMNSMSDENACAMTQQTTVANDISHSIQVI
SELSLESLEQTLDASQRGEQVSRLSTKTHNLSRQFWEQSVQRKV

Sequences:

>Translated_524_residues
MRNNQPVTQTEKTLTDNCILLSTTDLNGNIKYANEGFINVSGYSFDELHRQPHNLVRHPDMPEAAFESLWSRIKTGKPWV
GIVKNRSKNGDHYWVNAYVAPVFENGKIHEYQSVRRKATPEQINRAQGIYQAIQKGKQPKAIRKPLLGFSAKLYVWLMLT
VVIAAGLSSYSPIAAAILATVVGIAGLSVILKPFNTLVSQARNTIDDPLAAGVFTGRQDEIGKIGFALQFLLTETGGVVG
RMADSAGSIESLSASLNATIANTRQRADSQSMQTSQAATAMEEMSASFNEVSQNIHSAAREMSVSNLSAEKGHELLVRVI
ESINQLKDEVGNFASVVASIEQDSQDINNVLDVIRGIAEQTNLLALNAAIEAARAGESGRGFAVVADEVRQLSSRTSEST
SHIEAIVSKFRESTERAAKTMAAGQRKAEQSVDLAKQVDESFEALRESIIRMNSMSDENACAMTQQTTVANDISHSIQVI
SELSLESLEQTLDASQRGEQVSRLSTKTHNLSRQFWEQSVQRKV
>Mature_524_residues
MRNNQPVTQTEKTLTDNCILLSTTDLNGNIKYANEGFINVSGYSFDELHRQPHNLVRHPDMPEAAFESLWSRIKTGKPWV
GIVKNRSKNGDHYWVNAYVAPVFENGKIHEYQSVRRKATPEQINRAQGIYQAIQKGKQPKAIRKPLLGFSAKLYVWLMLT
VVIAAGLSSYSPIAAAILATVVGIAGLSVILKPFNTLVSQARNTIDDPLAAGVFTGRQDEIGKIGFALQFLLTETGGVVG
RMADSAGSIESLSASLNATIANTRQRADSQSMQTSQAATAMEEMSASFNEVSQNIHSAAREMSVSNLSAEKGHELLVRVI
ESINQLKDEVGNFASVVASIEQDSQDINNVLDVIRGIAEQTNLLALNAAIEAARAGESGRGFAVVADEVRQLSSRTSEST
SHIEAIVSKFRESTERAAKTMAAGQRKAEQSVDLAKQVDESFEALRESIIRMNSMSDENACAMTQQTTVANDISHSIQVI
SELSLESLEQTLDASQRGEQVSRLSTKTHNLSRQFWEQSVQRKV

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=542, Percent_Identity=31.7343173431734, Blast_Score=248, Evalue=6e-67,
Organism=Escherichia coli, GI2367378, Length=253, Percent_Identity=28.8537549407115, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1787690, Length=243, Percent_Identity=32.0987654320988, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1788195, Length=219, Percent_Identity=27.8538812785388, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1788194, Length=142, Percent_Identity=36.6197183098592, Blast_Score=87, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 57283; Mature: 57283

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNNQPVTQTEKTLTDNCILLSTTDLNGNIKYANEGFINVSGYSFDELHRQPHNLVRHPD
CCCCCCCCHHHHHHCCCEEEEEEECCCCCEEECCCCEEEECCCCHHHHHCCHHHHCCCCC
MPEAAFESLWSRIKTGKPWVGIVKNRSKNGDHYWVNAYVAPVFENGKIHEYQSVRRKATP
CCHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEEEEEEEECCCCCHHHHHHHHCCCH
EQINRAQGIYQAIQKGKQPKAIRKPLLGFSAKLYVWLMLTVVIAAGLSSYSPIAAAILAT
HHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
VVGIAGLSVILKPFNTLVSQARNTIDDPLAAGVFTGRQDEIGKIGFALQFLLTETGGVVG
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHH
RMADSAGSIESLSASLNATIANTRQRADSQSMQTSQAATAMEEMSASFNEVSQNIHSAAR
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EMSVSNLSAEKGHELLVRVIESINQLKDEVGNFASVVASIEQDSQDINNVLDVIRGIAEQ
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TNLLALNAAIEAARAGESGRGFAVVADEVRQLSSRTSESTSHIEAIVSKFRESTERAAKT
CCEEHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
MAAGQRKAEQSVDLAKQVDESFEALRESIIRMNSMSDENACAMTQQTTVANDISHSIQVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
SELSLESLEQTLDASQRGEQVSRLSTKTHNLSRQFWEQSVQRKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRNNQPVTQTEKTLTDNCILLSTTDLNGNIKYANEGFINVSGYSFDELHRQPHNLVRHPD
CCCCCCCCHHHHHHCCCEEEEEEECCCCCEEECCCCEEEECCCCHHHHHCCHHHHCCCCC
MPEAAFESLWSRIKTGKPWVGIVKNRSKNGDHYWVNAYVAPVFENGKIHEYQSVRRKATP
CCHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEEEEEEEECCCCCHHHHHHHHCCCH
EQINRAQGIYQAIQKGKQPKAIRKPLLGFSAKLYVWLMLTVVIAAGLSSYSPIAAAILAT
HHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
VVGIAGLSVILKPFNTLVSQARNTIDDPLAAGVFTGRQDEIGKIGFALQFLLTETGGVVG
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHH
RMADSAGSIESLSASLNATIANTRQRADSQSMQTSQAATAMEEMSASFNEVSQNIHSAAR
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EMSVSNLSAEKGHELLVRVIESINQLKDEVGNFASVVASIEQDSQDINNVLDVIRGIAEQ
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TNLLALNAAIEAARAGESGRGFAVVADEVRQLSSRTSESTSHIEAIVSKFRESTERAAKT
CCEEHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
MAAGQRKAEQSVDLAKQVDESFEALRESIIRMNSMSDENACAMTQQTTVANDISHSIQVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
SELSLESLEQTLDASQRGEQVSRLSTKTHNLSRQFWEQSVQRKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]