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The map label for this gene is pgsA [H]

Identifier: 167624268

GI number: 167624268

Start: 2832237

End: 2832785

Strand: Reverse

Name: pgsA [H]

Synonym: Shal_2344

Alternate gene names: 167624268

Gene position: 2832785-2832237 (Counterclockwise)

Preceding gene: 167624269

Following gene: 167624267

Centisome position: 54.2

GC content: 42.08

Gene sequence:

>549_bases
ATGCCGTTTAACATTCCTATTGCGTTAACACTTTTCAGGTTAGCTCTGTTACCTGTTTTTGTTGTACTTTTTTATATACC
AGAACCCTGGTCTCCTTTTGCCGCTGCATTTGTCTTTTGGCTCGCAGCTGTTACTGATGCACTCGATGGTTATGCCGCGC
GAAAGTTAAAGCAGTCGACTCGTTTTGGTGCGTTTCTCGATCCCGTTGCCGATAAGATAATGGTAACAACGGCTTTGGTC
TTACTTATCTCCGAATATAGTAATATTTGGTTAACACTGCCTGCACTATTTATGATTGGCCGCGAAATCGTCATCTCAGC
ATTACGCGAATGGATGGCTGAAATAGGTAAAAGAGGTGCGGTTGCAGTTTCTTGGATTGGCAAATATAAAACTGCTGCAC
AGATGGTGGCTATCACAGGATTAATTTGGCAACCAAATGAACTGTTAACTTATGCCGCCTTTGGGTTGTTTTACGTTGCA
GCAGTACTGACATTTTGGTCTATGATGAGCTATATTTTAGCTGCTTGGAAGGATTTAACAGCAGAATAG

Upstream 100 bases:

>100_bases
CCGGTATTAGCCTAGAAATGGCACAAACGATACATGATGCATTGCGAGGGTAGCAAAATTAAGGCAAGATTGGCGCTGCT
TTTGAATATTAGGTTCTAAA

Downstream 100 bases:

>100_bases
CTCGTTAAAGAATCAATGAGATCAATAAGTGGGCAGACAACCATTTATCGATAAATATAGCGTTGACTCTTGGCGTTTAA
TCGGTAGAATGCCATTCCGT

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 182; Mature: 181

Protein sequence:

>182_residues
MPFNIPIALTLFRLALLPVFVVLFYIPEPWSPFAAAFVFWLAAVTDALDGYAARKLKQSTRFGAFLDPVADKIMVTTALV
LLISEYSNIWLTLPALFMIGREIVISALREWMAEIGKRGAVAVSWIGKYKTAAQMVAITGLIWQPNELLTYAAFGLFYVA
AVLTFWSMMSYILAAWKDLTAE

Sequences:

>Translated_182_residues
MPFNIPIALTLFRLALLPVFVVLFYIPEPWSPFAAAFVFWLAAVTDALDGYAARKLKQSTRFGAFLDPVADKIMVTTALV
LLISEYSNIWLTLPALFMIGREIVISALREWMAEIGKRGAVAVSWIGKYKTAAQMVAITGLIWQPNELLTYAAFGLFYVA
AVLTFWSMMSYILAAWKDLTAE
>Mature_181_residues
PFNIPIALTLFRLALLPVFVVLFYIPEPWSPFAAAFVFWLAAVTDALDGYAARKLKQSTRFGAFLDPVADKIMVTTALVL
LISEYSNIWLTLPALFMIGREIVISALREWMAEIGKRGAVAVSWIGKYKTAAQMVAITGLIWQPNELLTYAAFGLFYVAA
VLTFWSMMSYILAAWKDLTAE

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=179, Percent_Identity=63.6871508379888, Blast_Score=229, Evalue=1e-61,
Organism=Saccharomyces cerevisiae, GI6320059, Length=108, Percent_Identity=40.7407407407407, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 20339; Mature: 20208

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFNIPIALTLFRLALLPVFVVLFYIPEPWSPFAAAFVFWLAAVTDALDGYAARKLKQST
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFGAFLDPVADKIMVTTALVLLISEYSNIWLTLPALFMIGREIVISALREWMAEIGKRGA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VAVSWIGKYKTAAQMVAITGLIWQPNELLTYAAFGLFYVAAVLTFWSMMSYILAAWKDLT
CHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AE
CC
>Mature Secondary Structure 
PFNIPIALTLFRLALLPVFVVLFYIPEPWSPFAAAFVFWLAAVTDALDGYAARKLKQST
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFGAFLDPVADKIMVTTALVLLISEYSNIWLTLPALFMIGREIVISALREWMAEIGKRGA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VAVSWIGKYKTAAQMVAITGLIWQPNELLTYAAFGLFYVAAVLTFWSMMSYILAAWKDLT
CHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AE
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]