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The map label for this gene is nadA [H]

Identifier: 167624155

GI number: 167624155

Start: 2705291

End: 2706358

Strand: Reverse

Name: nadA [H]

Synonym: Shal_2231

Alternate gene names: 167624155

Gene position: 2706358-2705291 (Counterclockwise)

Preceding gene: 167624156

Following gene: 167624154

Centisome position: 51.78

GC content: 46.91

Gene sequence:

>1068_bases
ATGAGCGCGTTCGCCCCAATTATCGAAAATATTGATTATCCTTTTCCACCAAAGCCTGCTCCCTTATCTGATCGTGAGAA
AGCTGAATCAAAAGCAAAAATTAAGCAGCTTTTAAAAGAAAAAGATGCGGTTTTGGTTGCGCATTATTATACCGACCCAG
AAATTCAAGCCTTAGCGGAAGAGACTGGCGGCTGTGTTTCTGACTCATTAGAGATGGCTCGCTTTGGTCGCGACCATCCG
GCTAAAACATTGATTGTTGCTGGCGTTAAGTTTATGGGGGAAACCTCAAAAATCTTAAGCCCTGATAAAACGATTCTAAT
GCCAACGCTTGAAGCGACATGTTCGCTCGACCTTGGCTGCCCAATAGAGACTTTCAGTGAGTTTTGTGACGCACACCCAG
ACCATACCGTGGTGGTGTACGCTAACACCTCGGCGGCAGTAAAAGCGCGAGCGGATTGGGTGGTTACCTCAAGTATTGCC
CTTGAAATTGTTGAGCATCTAGATAGTGAAGGTAAGAAAATTATCTGGGGGCCAGACCGTCACTTAGGCAGCTATATCGC
TAAGCAAACGGGTGCAGAGATGCTGATGTGGCAGGGCGAGTGTATCGTTCACGATGAGTTTCAAGCCAAGGCCTTACGTG
AGCTGAAGAAGCTACATCCAAACGCCGCGGTTTTAGTGCATCCAGAATCACCTGCTAGCGTAGTAGAACTCGCTGACGCA
GTCGGCTCAACCAGTCAGTTAATCAAAGCCGCACAAACGATGGATAACGATATGTTTATCGTGGCAACAGACAAAGGTAT
CTTCTATAAGATGCAGCAGGCCGCACCTGATAAAAATTTAATAGCTGCGCCGACTGGCGGTAATGGGGCGACGTGTAAGA
GCTGCGCTCATTGTCCTTGGATGGCCATGAATGGTCTTAAGGCGATTGAAAGTGCGCTAGAGAATAGTGACTCACAGCAA
CATGAGATCTTTGTTGATGATGCGCTGCGGCTCGATGCCCTCAAGCCATTGGATAGAATGTTGGACTTTGCAATGACTTT
GAATATGAAAGTCAAAGGTAATGCTTAG

Upstream 100 bases:

>100_bases
TGATAGCGCCTTTTTTATTTCTATTATCCTCGTAGTAGTTTTAAATTTGTGAACAATTCCGTATAATTCCGCTAATCTGT
TATTGCCCATTGGTTGTACT

Downstream 100 bases:

>100_bases
AATTCAACCTGTTATTTCAATGTTTTATATAACTGCATAACTTATGCAGTTGTATAAAACTTGATCTATAACAATAAGCT
CGTTAATACGGGCTTATTTT

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MSAFAPIIENIDYPFPPKPAPLSDREKAESKAKIKQLLKEKDAVLVAHYYTDPEIQALAEETGGCVSDSLEMARFGRDHP
AKTLIVAGVKFMGETSKILSPDKTILMPTLEATCSLDLGCPIETFSEFCDAHPDHTVVVYANTSAAVKARADWVVTSSIA
LEIVEHLDSEGKKIIWGPDRHLGSYIAKQTGAEMLMWQGECIVHDEFQAKALRELKKLHPNAAVLVHPESPASVVELADA
VGSTSQLIKAAQTMDNDMFIVATDKGIFYKMQQAAPDKNLIAAPTGGNGATCKSCAHCPWMAMNGLKAIESALENSDSQQ
HEIFVDDALRLDALKPLDRMLDFAMTLNMKVKGNA

Sequences:

>Translated_355_residues
MSAFAPIIENIDYPFPPKPAPLSDREKAESKAKIKQLLKEKDAVLVAHYYTDPEIQALAEETGGCVSDSLEMARFGRDHP
AKTLIVAGVKFMGETSKILSPDKTILMPTLEATCSLDLGCPIETFSEFCDAHPDHTVVVYANTSAAVKARADWVVTSSIA
LEIVEHLDSEGKKIIWGPDRHLGSYIAKQTGAEMLMWQGECIVHDEFQAKALRELKKLHPNAAVLVHPESPASVVELADA
VGSTSQLIKAAQTMDNDMFIVATDKGIFYKMQQAAPDKNLIAAPTGGNGATCKSCAHCPWMAMNGLKAIESALENSDSQQ
HEIFVDDALRLDALKPLDRMLDFAMTLNMKVKGNA
>Mature_354_residues
SAFAPIIENIDYPFPPKPAPLSDREKAESKAKIKQLLKEKDAVLVAHYYTDPEIQALAEETGGCVSDSLEMARFGRDHPA
KTLIVAGVKFMGETSKILSPDKTILMPTLEATCSLDLGCPIETFSEFCDAHPDHTVVVYANTSAAVKARADWVVTSSIAL
EIVEHLDSEGKKIIWGPDRHLGSYIAKQTGAEMLMWQGECIVHDEFQAKALRELKKLHPNAAVLVHPESPASVVELADAV
GSTSQLIKAAQTMDNDMFIVATDKGIFYKMQQAAPDKNLIAAPTGGNGATCKSCAHCPWMAMNGLKAIESALENSDSQQH
EIFVDDALRLDALKPLDRMLDFAMTLNMKVKGNA

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=336, Percent_Identity=72.3214285714286, Blast_Score=521, Evalue=1e-149,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 38638; Mature: 38506

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAFAPIIENIDYPFPPKPAPLSDREKAESKAKIKQLLKEKDAVLVAHYYTDPEIQALAE
CCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHH
ETGGCVSDSLEMARFGRDHPAKTLIVAGVKFMGETSKILSPDKTILMPTLEATCSLDLGC
HHCCHHHHHHHHHHCCCCCCCCEEEEHHHHHHCCCHHHCCCCCEEEEECCHHHEECCCCC
PIETFSEFCDAHPDHTVVVYANTSAAVKARADWVVTSSIALEIVEHLDSEGKKIIWGPDR
CHHHHHHHHHCCCCCEEEEEECCCCEEEECCCEEEHHHHHHHHHHHHCCCCCEEEECCCH
HLGSYIAKQTGAEMLMWQGECIVHDEFQAKALRELKKLHPNAAVLVHPESPASVVELADA
HHHHHHHHHCCCCEEEECCCEEEECHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHH
VGSTSQLIKAAQTMDNDMFIVATDKGIFYKMQQAAPDKNLIAAPTGGNGATCKSCAHCPW
HCCHHHHHHHHHHCCCCEEEEEECCCEEEEEHHCCCCCCEEEECCCCCCCCCHHHCCCCH
MAMNGLKAIESALENSDSQQHEIFVDDALRLDALKPLDRMLDFAMTLNMKVKGNA
HHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHEEEEEEECCC
>Mature Secondary Structure 
SAFAPIIENIDYPFPPKPAPLSDREKAESKAKIKQLLKEKDAVLVAHYYTDPEIQALAE
CCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHH
ETGGCVSDSLEMARFGRDHPAKTLIVAGVKFMGETSKILSPDKTILMPTLEATCSLDLGC
HHCCHHHHHHHHHHCCCCCCCCEEEEHHHHHHCCCHHHCCCCCEEEEECCHHHEECCCCC
PIETFSEFCDAHPDHTVVVYANTSAAVKARADWVVTSSIALEIVEHLDSEGKKIIWGPDR
CHHHHHHHHHCCCCCEEEEEECCCCEEEECCCEEEHHHHHHHHHHHHCCCCCEEEECCCH
HLGSYIAKQTGAEMLMWQGECIVHDEFQAKALRELKKLHPNAAVLVHPESPASVVELADA
HHHHHHHHHCCCCEEEECCCEEEECHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHH
VGSTSQLIKAAQTMDNDMFIVATDKGIFYKMQQAAPDKNLIAAPTGGNGATCKSCAHCPW
HCCHHHHHHHHHHCCCCEEEEEECCCEEEEEHHCCCCCCEEEECCCCCCCCCHHHCCCCH
MAMNGLKAIESALENSDSQQHEIFVDDALRLDALKPLDRMLDFAMTLNMKVKGNA
HHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]