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The map label for this gene is hlyB [H]

Identifier: 167624154

GI number: 167624154

Start: 2703106

End: 2705100

Strand: Reverse

Name: hlyB [H]

Synonym: Shal_2230

Alternate gene names: 167624154

Gene position: 2705100-2703106 (Counterclockwise)

Preceding gene: 167624155

Following gene: 167624153

Centisome position: 51.75

GC content: 45.56

Gene sequence:

>1995_bases
ATGAAACTAACTTTTATTAGTAGCCTCACTTTAAAGCAGAAATTTCTGATTGTTATCCTACCCCCGCTATTGGTTTCTAT
AATTTTTGGTGGACTCTATGCGAAAACCCAATACCAACTTAAAACGGAGCTTACCGAGGTTCTTGTATTAAGTGAGTTAG
CGGTTAACAACAGTAATCTGGTCCATGAACTCCAAAAAGAGAGGGGAATGAGCGCCGGATTTATCGGTTCAAGCGGGCAA
TCTTTCGCGCAAGAGCTGGCAAAGCAGCAACGCGCAACTGATACTCTGCTACAAAGTTATCAGCAGTTCCTCAATCTTAA
TGCCCTACCTGCCGCCTTTTCGACACAGATTACAACAGTGGAGTCATTAATAAAGCAAATTCCAGATATCCGAAATCGTG
TTAGTAATTTGTCTATTTCAGTAGCAGAGGAAGTGAAGTTTTATACTCAAATAAATGCTCTGTTATTGAGTATTGTCGAT
TTAACTGCGATTAATGCTGCTAACCAAGAGATAGCGATCCGTTCAGCAGCGTTTGCTGCTTATCTACAGATGAAAGAGAG
AGCGGGCTTAGAAAGAGCGGTGCTGAGTTCGACCTTTGGCAACCAAGGTTTTAAAGACGGGGTATACCGCAGATTTATTA
CTTTAGTTGCAGAGCAGGAAAGTTATCAAGAACGCTTTTTAGCCTTGGTCGATAAGCAAAACAGCAGTAAATACCAATCT
TTATTGAGTTCGACAGAACTTCTCGATGTCAACCGATATAGGGCAATCGGATTCGAACAGTTAGCCAGTGAAATAGAAGG
GCAGAAACCGGAGCAGTGGTTTCAGGTATCGACTAAACGCATCGAATTGTTAGCCCAGTTTGAGCATCAATTATCGCAGG
ATTTACTGATGGTGACTAAGCAGCGCTTGTCGTCAGCTACACAAGGATTTTATATTAGTGTATTGAGTCTCCTGTTTGCA
GCCACAACCGTGTTATTACTCTCGTTTTCGGTGCTGCACTTTATACACCGTAGTGTTGCTAATTTACATAACTCAGTAAC
GAGCGCCAGAACAAATTTCGATCTCAGCGTTAGAATAGAACAGCACAGCAAAGATGAGTTTGGCGAATTAGCAGGCGCCT
TCAATGAAATGATGGCGGATTTTGAACGTGTGATCGAGCATGTTCGTAAAAACTCGACCTCTTTATTGACCGCCGTCTCC
AAGATGGAGCAATGCTCTACTCAACTTCGCACCGATGTCGAACAGGGACATGGAGAAGCTGAGCAGGTTGCCTCTGCAAT
GACTGAGATGAGTGCTACCGTCGCTGAAATCGCCATAAACGCCGAGCGTGCCTCTGAAGCTTCAACCCAGGCCAATACCG
AGGCCAAAGAGGGCTATGCCGAGGTGGGCCGTACGAGTGAGTCGATTAGCGTACTTGCCGACGATATCCGAGGGTCGGCA
GATGCGCTACAAAAGCTTGAGCAAGATATACAAAGTATTGTTGCCGTGTCTGATGTGATAAGTGGTATTGCCGAACAGAC
TAATCTGTTAGCCCTTAACGCCGCGATTGAAGCCGCGAGAGCAGGCGAATCCGGCAGAGGCTTTGCGGTTGTGGCTGATG
AAGTTCGTAGCCTCGCGCAGAGAGCCCAAAGCGCTACAGGGGACATAAAAGCCATGACCGATCGCCTCCGTAGTGGTGCT
AATATTGCGGTATATGCGATGGAGCGTGGTATGAAGCAGACAGATGATAGCGTAGTAGAAGCATCCAGAGCCAGCGCAGA
GCTTGATAAAATTGTTAATCACATAGGTGTCATCGAGAGCATGAACGAACAGATTGCCGCCTCGACTCACGAGCAATCAG
CCGTTGCCGAAGAAGTGAACGTAAATGCGCTTAAAATTAGTGAGATCTATTTGCAAACCCATAGTGTTGCAGATCAGCTT
AGCTCGCTAACAGACCAGTTAGTGCAAGACACCGCCGAGATGTCAAAAGAGGTTAAAAAGTTCAAGTTGAGCTAA

Upstream 100 bases:

>100_bases
GGCTTATTTTTTGAAACAAATTTAAAAAAATATTTACCTAGATGAAGTTTCGACTATGCTAAGGCGATAATTAATAATAT
TTAAATAGGTTGTTTTGCGA

Downstream 100 bases:

>100_bases
TTCCCTCAATAAAATGAGGTAACTGGCTAGCAATTATGCAAACGTTTGAGATTACGGCTATTTGTCTTGACGCAATTGGG
CCTTTTAAGTAAAGTAGCGC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 664; Mature: 664

Protein sequence:

>664_residues
MKLTFISSLTLKQKFLIVILPPLLVSIIFGGLYAKTQYQLKTELTEVLVLSELAVNNSNLVHELQKERGMSAGFIGSSGQ
SFAQELAKQQRATDTLLQSYQQFLNLNALPAAFSTQITTVESLIKQIPDIRNRVSNLSISVAEEVKFYTQINALLLSIVD
LTAINAANQEIAIRSAAFAAYLQMKERAGLERAVLSSTFGNQGFKDGVYRRFITLVAEQESYQERFLALVDKQNSSKYQS
LLSSTELLDVNRYRAIGFEQLASEIEGQKPEQWFQVSTKRIELLAQFEHQLSQDLLMVTKQRLSSATQGFYISVLSLLFA
ATTVLLLSFSVLHFIHRSVANLHNSVTSARTNFDLSVRIEQHSKDEFGELAGAFNEMMADFERVIEHVRKNSTSLLTAVS
KMEQCSTQLRTDVEQGHGEAEQVASAMTEMSATVAEIAINAERASEASTQANTEAKEGYAEVGRTSESISVLADDIRGSA
DALQKLEQDIQSIVAVSDVISGIAEQTNLLALNAAIEAARAGESGRGFAVVADEVRSLAQRAQSATGDIKAMTDRLRSGA
NIAVYAMERGMKQTDDSVVEASRASAELDKIVNHIGVIESMNEQIAASTHEQSAVAEEVNVNALKISEIYLQTHSVADQL
SSLTDQLVQDTAEMSKEVKKFKLS

Sequences:

>Translated_664_residues
MKLTFISSLTLKQKFLIVILPPLLVSIIFGGLYAKTQYQLKTELTEVLVLSELAVNNSNLVHELQKERGMSAGFIGSSGQ
SFAQELAKQQRATDTLLQSYQQFLNLNALPAAFSTQITTVESLIKQIPDIRNRVSNLSISVAEEVKFYTQINALLLSIVD
LTAINAANQEIAIRSAAFAAYLQMKERAGLERAVLSSTFGNQGFKDGVYRRFITLVAEQESYQERFLALVDKQNSSKYQS
LLSSTELLDVNRYRAIGFEQLASEIEGQKPEQWFQVSTKRIELLAQFEHQLSQDLLMVTKQRLSSATQGFYISVLSLLFA
ATTVLLLSFSVLHFIHRSVANLHNSVTSARTNFDLSVRIEQHSKDEFGELAGAFNEMMADFERVIEHVRKNSTSLLTAVS
KMEQCSTQLRTDVEQGHGEAEQVASAMTEMSATVAEIAINAERASEASTQANTEAKEGYAEVGRTSESISVLADDIRGSA
DALQKLEQDIQSIVAVSDVISGIAEQTNLLALNAAIEAARAGESGRGFAVVADEVRSLAQRAQSATGDIKAMTDRLRSGA
NIAVYAMERGMKQTDDSVVEASRASAELDKIVNHIGVIESMNEQIAASTHEQSAVAEEVNVNALKISEIYLQTHSVADQL
SSLTDQLVQDTAEMSKEVKKFKLS
>Mature_664_residues
MKLTFISSLTLKQKFLIVILPPLLVSIIFGGLYAKTQYQLKTELTEVLVLSELAVNNSNLVHELQKERGMSAGFIGSSGQ
SFAQELAKQQRATDTLLQSYQQFLNLNALPAAFSTQITTVESLIKQIPDIRNRVSNLSISVAEEVKFYTQINALLLSIVD
LTAINAANQEIAIRSAAFAAYLQMKERAGLERAVLSSTFGNQGFKDGVYRRFITLVAEQESYQERFLALVDKQNSSKYQS
LLSSTELLDVNRYRAIGFEQLASEIEGQKPEQWFQVSTKRIELLAQFEHQLSQDLLMVTKQRLSSATQGFYISVLSLLFA
ATTVLLLSFSVLHFIHRSVANLHNSVTSARTNFDLSVRIEQHSKDEFGELAGAFNEMMADFERVIEHVRKNSTSLLTAVS
KMEQCSTQLRTDVEQGHGEAEQVASAMTEMSATVAEIAINAERASEASTQANTEAKEGYAEVGRTSESISVLADDIRGSA
DALQKLEQDIQSIVAVSDVISGIAEQTNLLALNAAIEAARAGESGRGFAVVADEVRSLAQRAQSATGDIKAMTDRLRSGA
NIAVYAMERGMKQTDDSVVEASRASAELDKIVNHIGVIESMNEQIAASTHEQSAVAEEVNVNALKISEIYLQTHSVADQL
SSLTDQLVQDTAEMSKEVKKFKLS

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=266, Percent_Identity=33.0827067669173, Blast_Score=119, Evalue=7e-28,
Organism=Escherichia coli, GI2367378, Length=252, Percent_Identity=35.3174603174603, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1788194, Length=310, Percent_Identity=29.3548387096774, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1787690, Length=391, Percent_Identity=26.0869565217391, Blast_Score=110, Evalue=4e-25,
Organism=Escherichia coli, GI1789453, Length=264, Percent_Identity=31.8181818181818, Blast_Score=92, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 72866; Mature: 72866

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTFISSLTLKQKFLIVILPPLLVSIIFGGLYAKTQYQLKTELTEVLVLSELAVNNSNL
CEEEEEHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VHELQKERGMSAGFIGSSGQSFAQELAKQQRATDTLLQSYQQFLNLNALPAAFSTQITTV
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
ESLIKQIPDIRNRVSNLSISVAEEVKFYTQINALLLSIVDLTAINAANQEIAIRSAAFAA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
YLQMKERAGLERAVLSSTFGNQGFKDGVYRRFITLVAEQESYQERFLALVDKQNSSKYQS
HHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LLSSTELLDVNRYRAIGFEQLASEIEGQKPEQWFQVSTKRIELLAQFEHQLSQDLLMVTK
HHHHHHHHCCHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRLSSATQGFYISVLSLLFAATTVLLLSFSVLHFIHRSVANLHNSVTSARTNFDLSVRIE
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
QHSKDEFGELAGAFNEMMADFERVIEHVRKNSTSLLTAVSKMEQCSTQLRTDVEQGHGEA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHH
EQVASAMTEMSATVAEIAINAERASEASTQANTEAKEGYAEVGRTSESISVLADDIRGSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHCCCH
DALQKLEQDIQSIVAVSDVISGIAEQTNLLALNAAIEAARAGESGRGFAVVADEVRSLAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHH
RAQSATGDIKAMTDRLRSGANIAVYAMERGMKQTDDSVVEASRASAELDKIVNHIGVIES
HHHHCCCHHHHHHHHHHCCCCEEEEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MNEQIAASTHEQSAVAEEVNVNALKISEIYLQTHSVADQLSSLTDQLVQDTAEMSKEVKK
HHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FKLS
HCCC
>Mature Secondary Structure
MKLTFISSLTLKQKFLIVILPPLLVSIIFGGLYAKTQYQLKTELTEVLVLSELAVNNSNL
CEEEEEHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VHELQKERGMSAGFIGSSGQSFAQELAKQQRATDTLLQSYQQFLNLNALPAAFSTQITTV
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
ESLIKQIPDIRNRVSNLSISVAEEVKFYTQINALLLSIVDLTAINAANQEIAIRSAAFAA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
YLQMKERAGLERAVLSSTFGNQGFKDGVYRRFITLVAEQESYQERFLALVDKQNSSKYQS
HHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LLSSTELLDVNRYRAIGFEQLASEIEGQKPEQWFQVSTKRIELLAQFEHQLSQDLLMVTK
HHHHHHHHCCHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRLSSATQGFYISVLSLLFAATTVLLLSFSVLHFIHRSVANLHNSVTSARTNFDLSVRIE
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
QHSKDEFGELAGAFNEMMADFERVIEHVRKNSTSLLTAVSKMEQCSTQLRTDVEQGHGEA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHH
EQVASAMTEMSATVAEIAINAERASEASTQANTEAKEGYAEVGRTSESISVLADDIRGSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHCCCH
DALQKLEQDIQSIVAVSDVISGIAEQTNLLALNAAIEAARAGESGRGFAVVADEVRSLAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHH
RAQSATGDIKAMTDRLRSGANIAVYAMERGMKQTDDSVVEASRASAELDKIVNHIGVIES
HHHHCCCHHHHHHHHHHCCCCEEEEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MNEQIAASTHEQSAVAEEVNVNALKISEIYLQTHSVADQLSSLTDQLVQDTAEMSKEVKK
HHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FKLS
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]