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The map label for this gene is aspC [H]

Identifier: 167624136

GI number: 167624136

Start: 2674889

End: 2676082

Strand: Reverse

Name: aspC [H]

Synonym: Shal_2212

Alternate gene names: 167624136

Gene position: 2676082-2674889 (Counterclockwise)

Preceding gene: 167624137

Following gene: 167624133

Centisome position: 51.2

GC content: 44.39

Gene sequence:

>1194_bases
ATGATATTTTCCCAGGTTGAACTGGCCCCAGCCGATCCAATTTTAGGTTTAACAGATGCTTTTAAAGCAGATCTTCGCGA
CAATAAAGTGAACTTAGGCGTCGGTATTTATAAAGATGAATCTGGCCAGACACCAATCCTAAAGTCTGTAAAATTTGCAG
AAGAAAAACTGTTAGGAACCGAGAAAAGTAAAAGTTACCTCGGTATGGAAGGCGTCCAAGCCTACAATAGTGCCGTTCAA
AGTTTACTATTCGGCGCTGAACATGATGTGGTATCTCAGGCCCGTGCATTAACGGCACAGGCTCCTGGCGGAACCGGCTC
TTTAAGAGTTGCGGCAGAATTTCTCGTTCGTCATACGCCAGCAAAAACCATCTGGATAAGTAATCCTACTTGGGCAAACC
ACAATAATATTTTTGGCACAGCGGGTCTGGAGATTGCAGAGTACCGTTATTATAAAGCTGAAACCCATGGTTTAGATTTC
GAAGCGATGCTGACTGATCTACAGGGCGCTAAAGCAGGCGATCTAGTCTTACTTCATGGCTGCTGTCATAACCCAACGGG
TATCGACTTAAATCTAGAGCAGTGGCAGCAGATTGCTGACTTGTGTTTAGAAAAATCATTAGTACCGCTTTTCGATTTCG
CTTACCAAGGTTTCGGCGCCGGTGTTGAAGAAGACGCCCAAGGCCTGCGTATTGTTGCCAATACTGTGCCTGAATTGATT
GTTGCTAACTCTTTTTCTAAGAACTTCGGCCTATACAATGAGCGTATCGGTGCGGTAACTGTTGTCGCTTCTAATAGCGG
CGAAGCCGTTAATGCATTTAGCCAAATTAAAAGCACGATCCGCGCGTCTTATTCGAACCCTCCAGCGCACGGAGCGTTAA
TTGTTAGCACGATTTTAGGTGATGAAACACTTAAGCAGCTATGGCATGACGAACTCAAAGAGATGCGTGAACGTATTGCT
GAAATGCGTACGCTATTTGTTGAGTCATTAAAAGCCGCTGGCGTTGAGCATAACTTCGATTTTATCTCAGGTCAAAACGG
GATGTTTAGCTTCTCGGGACTTAACAAAGAGCAGGTTAACCGTTTAAGAGAAGAGTTTGGTGTTTACATCGTTGGTTCTG
GTCGTATTAGTGTTGCGGGTATGACGAAAACCAACATGCCTGTGATCTGTGAAGCAATTGCTAAGGTTCTTTAA

Upstream 100 bases:

>100_bases
AAAATTTGCTAATAGTCGTAGAACTCCCTTTCTCCTGCTTAGCTTCAATGTTATAAATACACGCGATAACCCTACACTTA
TAATATTTAGGAAAGCCGTC

Downstream 100 bases:

>100_bases
TCTAGCGATTGCGTGAGTCAAATAGCAGAGAGCAAGCCGAGCATTGCAAAACTAAATGCGCGTTAGTGAACCCACTACGC
GCATTTTTTATGCTTAAAAC

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MIFSQVELAPADPILGLTDAFKADLRDNKVNLGVGIYKDESGQTPILKSVKFAEEKLLGTEKSKSYLGMEGVQAYNSAVQ
SLLFGAEHDVVSQARALTAQAPGGTGSLRVAAEFLVRHTPAKTIWISNPTWANHNNIFGTAGLEIAEYRYYKAETHGLDF
EAMLTDLQGAKAGDLVLLHGCCHNPTGIDLNLEQWQQIADLCLEKSLVPLFDFAYQGFGAGVEEDAQGLRIVANTVPELI
VANSFSKNFGLYNERIGAVTVVASNSGEAVNAFSQIKSTIRASYSNPPAHGALIVSTILGDETLKQLWHDELKEMRERIA
EMRTLFVESLKAAGVEHNFDFISGQNGMFSFSGLNKEQVNRLREEFGVYIVGSGRISVAGMTKTNMPVICEAIAKVL

Sequences:

>Translated_397_residues
MIFSQVELAPADPILGLTDAFKADLRDNKVNLGVGIYKDESGQTPILKSVKFAEEKLLGTEKSKSYLGMEGVQAYNSAVQ
SLLFGAEHDVVSQARALTAQAPGGTGSLRVAAEFLVRHTPAKTIWISNPTWANHNNIFGTAGLEIAEYRYYKAETHGLDF
EAMLTDLQGAKAGDLVLLHGCCHNPTGIDLNLEQWQQIADLCLEKSLVPLFDFAYQGFGAGVEEDAQGLRIVANTVPELI
VANSFSKNFGLYNERIGAVTVVASNSGEAVNAFSQIKSTIRASYSNPPAHGALIVSTILGDETLKQLWHDELKEMRERIA
EMRTLFVESLKAAGVEHNFDFISGQNGMFSFSGLNKEQVNRLREEFGVYIVGSGRISVAGMTKTNMPVICEAIAKVL
>Mature_397_residues
MIFSQVELAPADPILGLTDAFKADLRDNKVNLGVGIYKDESGQTPILKSVKFAEEKLLGTEKSKSYLGMEGVQAYNSAVQ
SLLFGAEHDVVSQARALTAQAPGGTGSLRVAAEFLVRHTPAKTIWISNPTWANHNNIFGTAGLEIAEYRYYKAETHGLDF
EAMLTDLQGAKAGDLVLLHGCCHNPTGIDLNLEQWQQIADLCLEKSLVPLFDFAYQGFGAGVEEDAQGLRIVANTVPELI
VANSFSKNFGLYNERIGAVTVVASNSGEAVNAFSQIKSTIRASYSNPPAHGALIVSTILGDETLKQLWHDELKEMRERIA
EMRTLFVESLKAAGVEHNFDFISGQNGMFSFSGLNKEQVNRLREEFGVYIVGSGRISVAGMTKTNMPVICEAIAKVL

Specific function: Unknown

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=396, Percent_Identity=41.6666666666667, Blast_Score=327, Evalue=9e-90,
Organism=Homo sapiens, GI4504067, Length=410, Percent_Identity=39.2682926829268, Blast_Score=295, Evalue=5e-80,
Organism=Homo sapiens, GI117414139, Length=386, Percent_Identity=26.1658031088083, Blast_Score=141, Evalue=1e-33,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=59.3434343434343, Blast_Score=509, Evalue=1e-145,
Organism=Escherichia coli, GI1790488, Length=397, Percent_Identity=45.088161209068, Blast_Score=373, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI71981858, Length=395, Percent_Identity=42.5316455696203, Blast_Score=352, Evalue=2e-97,
Organism=Caenorhabditis elegans, GI25147133, Length=395, Percent_Identity=42.0253164556962, Blast_Score=340, Evalue=6e-94,
Organism=Caenorhabditis elegans, GI17569539, Length=394, Percent_Identity=36.2944162436548, Blast_Score=275, Evalue=3e-74,
Organism=Caenorhabditis elegans, GI17569537, Length=387, Percent_Identity=29.7157622739018, Blast_Score=190, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI25147136, Length=211, Percent_Identity=40.7582938388626, Blast_Score=188, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17550384, Length=263, Percent_Identity=35.361216730038, Blast_Score=174, Evalue=8e-44,
Organism=Saccharomyces cerevisiae, GI6323055, Length=406, Percent_Identity=39.6551724137931, Blast_Score=306, Evalue=3e-84,
Organism=Saccharomyces cerevisiae, GI6322743, Length=435, Percent_Identity=35.1724137931034, Blast_Score=243, Evalue=5e-65,
Organism=Drosophila melanogaster, GI24580970, Length=397, Percent_Identity=42.0654911838791, Blast_Score=327, Evalue=7e-90,
Organism=Drosophila melanogaster, GI24580972, Length=397, Percent_Identity=42.0654911838791, Blast_Score=327, Evalue=8e-90,
Organism=Drosophila melanogaster, GI19920542, Length=392, Percent_Identity=41.8367346938776, Blast_Score=320, Evalue=1e-87,
Organism=Drosophila melanogaster, GI19922362, Length=395, Percent_Identity=41.2658227848101, Blast_Score=312, Evalue=2e-85,
Organism=Drosophila melanogaster, GI24654046, Length=395, Percent_Identity=41.2658227848101, Blast_Score=312, Evalue=3e-85,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43166; Mature: 43166

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFSQVELAPADPILGLTDAFKADLRDNKVNLGVGIYKDESGQTPILKSVKFAEEKLLGT
CCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHCCC
EKSKSYLGMEGVQAYNSAVQSLLFGAEHDVVSQARALTAQAPGGTGSLRVAAEFLVRHTP
CCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEECCCCCCCHHHHHHHHHHHCCC
AKTIWISNPTWANHNNIFGTAGLEIAEYRYYKAETHGLDFEAMLTDLQGAKAGDLVLLHG
CCEEEECCCCCCCCCCEEECCCCEEHHHEEEECCCCCCCHHHHHHHHCCCCCCCEEEEEC
CCHNPTGIDLNLEQWQQIADLCLEKSLVPLFDFAYQGFGAGVEEDAQGLRIVANTVPELI
CCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHCCCCEEHHHHHHHHH
VANSFSKNFGLYNERIGAVTVVASNSGEAVNAFSQIKSTIRASYSNPPAHGALIVSTILG
HHCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHC
DETLKQLWHDELKEMRERIAEMRTLFVESLKAAGVEHNFDFISGQNGMFSFSGLNKEQVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCEEEECCCCHHHHH
RLREEFGVYIVGSGRISVAGMTKTNMPVICEAIAKVL
HHHHHCCEEEEECCEEEEEECCCCCCHHHHHHHHHHC
>Mature Secondary Structure
MIFSQVELAPADPILGLTDAFKADLRDNKVNLGVGIYKDESGQTPILKSVKFAEEKLLGT
CCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHCCC
EKSKSYLGMEGVQAYNSAVQSLLFGAEHDVVSQARALTAQAPGGTGSLRVAAEFLVRHTP
CCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEECCCCCCCHHHHHHHHHHHCCC
AKTIWISNPTWANHNNIFGTAGLEIAEYRYYKAETHGLDFEAMLTDLQGAKAGDLVLLHG
CCEEEECCCCCCCCCCEEECCCCEEHHHEEEECCCCCCCHHHHHHHHCCCCCCCEEEEEC
CCHNPTGIDLNLEQWQQIADLCLEKSLVPLFDFAYQGFGAGVEEDAQGLRIVANTVPELI
CCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHCCCCEEHHHHHHHHH
VANSFSKNFGLYNERIGAVTVVASNSGEAVNAFSQIKSTIRASYSNPPAHGALIVSTILG
HHCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHC
DETLKQLWHDELKEMRERIAEMRTLFVESLKAAGVEHNFDFISGQNGMFSFSGLNKEQVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCEEEECCCCHHHHH
RLREEFGVYIVGSGRISVAGMTKTNMPVICEAIAKVL
HHHHHCCEEEEECCEEEEEECCCCCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6378205; 3897210; 3521591; 3298240; 8905232; 9278503; 9298646; 1868057; 2007566; 2513875; 1993208; 9891001 [H]