BacMap

Definition	Shewanella halifaxensis HAW-EB4 chromosome, complete genome.
Accession	NC_010334
Length	5,226,917

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The map label for this gene is kduD [C]

Identifier: 167624057

GI number: 167624057

Start: 2568326

End: 2569204

Strand: Direct

Name: kduD [C]

Synonym: Shal_2133

Alternate gene names: 167624057

Gene position: 2568326-2569204 (Clockwise)

Preceding gene: 167624056

Following gene: 167624058

Centisome position: 49.14

GC content: 50.28

Gene sequence:

>879_bases
ATGAAAGCATGTAATTCGAGAACCGTAATTATTACCGGCAGTGGCGGTGGCCTAGGTCGAGCTTATGCGTTAGCGTTGGC
CGCAGAAGGAGCAAATGTTGTTGTTAATGATATTCGTGCCGGCGCTGCTGCAGCCGTTGTGGACGAGATCTTGACTCAAG
GTGGGCAAGCTATTGCGAACTCAGATGACATTACTCGCATGGACACCGCAACTAACATCGTCGATGCTGCGTTAGAGGCA
TTTGGTGAGGTACATGTACTGATTAATAATGCCGGTGTTTTGGCTGACAGAATGTTTATTAGCCTTAGCGAAGCAGATTG
GGACAAGGTCATGCAAGTCCACCTAAAGGGCCATTTTTGTTTAGCTAATATTTTGGGGCGTCGTTGGCGTGACCTTGCCA
AGGCCGGTCAACCGGTTGATGCACGGATCATCAATACTAGCTCAGGTGCAGGGCTTCAAGGCTCTATTGGGCAGTCAAAC
TACTCTGCTGCTAAAGGCGGCATTGCATCGTTAACATTAGTTCAAGCAGCCGAACTGGGGCGTTACGGGGTAACAGTAAA
TGCACTCGCGCCCGCAGCCCGCACCTCTATGACCCAAAGCGCCATGCCTGATGTGGTAAAGAAACCGGAAGATGGTAGTT
TTGACCTGTGGGCGCCGGAAAATGTTGCGCCGCTGGTTGTATGGTTAAGCAGTTCTGAATCGAAGCATATCTCAGGACAG
ATCTTGGAAAGCCAAGGTGGACGGATCTCCTTATGTGATGGTTGGCGTACCGGTTTGACGGTAGATCATGGTAAACGTTG
GGATATCGCTGAGGTTGGCCCCGCTATTGACCAACTCATTGGAAAAGCCCCCAAAGCACAGAAAGTGTGGGGTAGCTAA

Upstream 100 bases:

>100_bases
GGCGGTGGCCTTGCCAATGTCACCATTATTGAGCGTTTGTCATAAGCGACTTGAGCCAATACAAAAACAATAAAAGTTAG
TGCAATTGAGGGAGCATAGA

Downstream 100 bases:

>100_bases
GGATTTTAGCTAAAAGCCTTTAGCTGAATTGAGACAATTGACCACGATAATGGATTAGCACCGAGGACAAATTGCAATGA
ACGATAATATTGATAATAAA

Product: short chain dehydrogenase

Products: @DEHY06.txt*3-Dehydro-2- Deoxy-D-Gluconate!; NADH. [C]

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MKACNSRTVIITGSGGGLGRAYALALAAEGANVVVNDIRAGAAAAVVDEILTQGGQAIANSDDITRMDTATNIVDAALEA
FGEVHVLINNAGVLADRMFISLSEADWDKVMQVHLKGHFCLANILGRRWRDLAKAGQPVDARIINTSSGAGLQGSIGQSN
YSAAKGGIASLTLVQAAELGRYGVTVNALAPAARTSMTQSAMPDVVKKPEDGSFDLWAPENVAPLVVWLSSSESKHISGQ
ILESQGGRISLCDGWRTGLTVDHGKRWDIAEVGPAIDQLIGKAPKAQKVWGS

Sequences:

>Translated_292_residues
MKACNSRTVIITGSGGGLGRAYALALAAEGANVVVNDIRAGAAAAVVDEILTQGGQAIANSDDITRMDTATNIVDAALEA
FGEVHVLINNAGVLADRMFISLSEADWDKVMQVHLKGHFCLANILGRRWRDLAKAGQPVDARIINTSSGAGLQGSIGQSN
YSAAKGGIASLTLVQAAELGRYGVTVNALAPAARTSMTQSAMPDVVKKPEDGSFDLWAPENVAPLVVWLSSSESKHISGQ
ILESQGGRISLCDGWRTGLTVDHGKRWDIAEVGPAIDQLIGKAPKAQKVWGS
>Mature_292_residues
MKACNSRTVIITGSGGGLGRAYALALAAEGANVVVNDIRAGAAAAVVDEILTQGGQAIANSDDITRMDTATNIVDAALEA
FGEVHVLINNAGVLADRMFISLSEADWDKVMQVHLKGHFCLANILGRRWRDLAKAGQPVDARIINTSSGAGLQGSIGQSN
YSAAKGGIASLTLVQAAELGRYGVTVNALAPAARTSMTQSAMPDVVKKPEDGSFDLWAPENVAPLVVWLSSSESKHISGQ
ILESQGGRISLCDGWRTGLTVDHGKRWDIAEVGPAIDQLIGKAPKAQKVWGS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4504505, Length=261, Percent_Identity=40.2298850574713, Blast_Score=166, Evalue=2e-41,
Organism=Homo sapiens, GI15277342, Length=249, Percent_Identity=34.136546184739, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI40254992, Length=243, Percent_Identity=31.2757201646091, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI19923817, Length=260, Percent_Identity=26.5384615384615, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI4758504, Length=217, Percent_Identity=30.4147465437788, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI7705925, Length=248, Percent_Identity=28.6290322580645, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI31542939, Length=215, Percent_Identity=31.1627906976744, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI83715985, Length=217, Percent_Identity=29.9539170506912, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI32483357, Length=252, Percent_Identity=25.3968253968254, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1789208, Length=248, Percent_Identity=27.4193548387097, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=29.6747967479675, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1790717, Length=258, Percent_Identity=28.6821705426357, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI1787905, Length=245, Percent_Identity=31.8367346938775, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI87082160, Length=251, Percent_Identity=29.0836653386454, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1788459, Length=247, Percent_Identity=30.3643724696356, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789057, Length=263, Percent_Identity=30.4182509505703, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI87082100, Length=258, Percent_Identity=27.5193798449612, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI2367175, Length=254, Percent_Identity=30.7086614173228, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787526, Length=251, Percent_Identity=26.2948207171315, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17568967, Length=275, Percent_Identity=36.3636363636364, Blast_Score=160, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI17555706, Length=254, Percent_Identity=31.1023622047244, Blast_Score=107, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI25147288, Length=245, Percent_Identity=31.4285714285714, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17562910, Length=276, Percent_Identity=30.4347826086957, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI72000259, Length=278, Percent_Identity=28.0575539568345, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=273, Percent_Identity=25.6410256410256, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17561402, Length=251, Percent_Identity=26.2948207171315, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=270, Percent_Identity=26.2962962962963, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=283, Percent_Identity=28.6219081272085, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17564282, Length=197, Percent_Identity=27.9187817258883, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=262, Percent_Identity=26.3358778625954, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=269, Percent_Identity=25.6505576208178, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17536651, Length=288, Percent_Identity=26.3888888888889, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=199, Percent_Identity=28.1407035175879, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=203, Percent_Identity=28.0788177339901, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71982365, Length=200, Percent_Identity=28, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17538182, Length=217, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=264, Percent_Identity=28.030303030303, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17567345, Length=201, Percent_Identity=29.3532338308458, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=260, Percent_Identity=26.9230769230769, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17531453, Length=268, Percent_Identity=26.1194029850746, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17555612, Length=223, Percent_Identity=29.1479820627803, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71994604, Length=255, Percent_Identity=24.7058823529412, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=282, Percent_Identity=25.886524822695, Blast_Score=64, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI71994600, Length=256, Percent_Identity=25.390625, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=250, Percent_Identity=42, Blast_Score=170, Evalue=3e-43,
Organism=Drosophila melanogaster, GI18859837, Length=270, Percent_Identity=37.7777777777778, Blast_Score=153, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24639444, Length=246, Percent_Identity=29.6747967479675, Blast_Score=108, Evalue=3e-24,
Organism=Drosophila melanogaster, GI17737361, Length=208, Percent_Identity=28.8461538461538, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28571526, Length=263, Percent_Identity=25.8555133079848, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI23397609, Length=260, Percent_Identity=26.5384615384615, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24644339, Length=258, Percent_Identity=27.1317829457364, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24649181, Length=159, Percent_Identity=30.8176100628931, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21357673, Length=257, Percent_Identity=27.2373540856031, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21357041, Length=263, Percent_Identity=25.4752851711027, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24640492, Length=164, Percent_Identity=26.219512195122, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.125 [C]

Molecular weight: Translated: 30482; Mature: 30482

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKACNSRTVIITGSGGGLGRAYALALAAEGANVVVNDIRAGAAAAVVDEILTQGGQAIAN
CCCCCCCEEEEEECCCCCHHHHEEEEECCCCCEEEECCCCCHHHHHHHHHHHCCCCEECC
SDDITRMDTATNIVDAALEAFGEVHVLINNAGVLADRMFISLSEADWDKVMQVHLKGHFC
CCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEHEEEEECCCCHHHHHHHHHCCCHH
LANILGRRWRDLAKAGQPVDARIINTSSGAGLQGSIGQSNYSAAKGGIASLTLVQAAELG
HHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHCC
RYGVTVNALAPAARTSMTQSAMPDVVKKPEDGSFDLWAPENVAPLVVWLSSSESKHISGQ
CCCEEEEHHCCHHHHHHHHHHCHHHHCCCCCCCEECCCCCCCCEEEEEEECCCCCCCCCE
ILESQGGRISLCDGWRTGLTVDHGKRWDIAEVGPAIDQLIGKAPKAQKVWGS
EEECCCCEEEEECCCCCCEEECCCCCCCHHHHCHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKACNSRTVIITGSGGGLGRAYALALAAEGANVVVNDIRAGAAAAVVDEILTQGGQAIAN
CCCCCCCEEEEEECCCCCHHHHEEEEECCCCCEEEECCCCCHHHHHHHHHHHCCCCEECC
SDDITRMDTATNIVDAALEAFGEVHVLINNAGVLADRMFISLSEADWDKVMQVHLKGHFC
CCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEHEEEEECCCCHHHHHHHHHCCCHH
LANILGRRWRDLAKAGQPVDARIINTSSGAGLQGSIGQSNYSAAKGGIASLTLVQAAELG
HHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHCC
RYGVTVNALAPAARTSMTQSAMPDVVKKPEDGSFDLWAPENVAPLVVWLSSSESKHISGQ
CCCEEEEHHCCHHHHHHHHHHCHHHHCCCCCCCEECCCCCCCCEEEEEEECCCCCCCCCE
ILESQGGRISLCDGWRTGLTVDHGKRWDIAEVGPAIDQLIGKAPKAQKVWGS
EEECCCCEEEEECCCCCCEEECCCCCCCHHHHCHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NAD+ [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 15.4 {2-deoxygluconate}} [C]

Substrates: @DEOX03.txt*2-Deoxy-D-Gluconate!; NAD(+) [C]

Specific reaction: @DEOX03.txt*2-Deoxy-D-Gluconate! + NAD(+) = @DEHY06.txt*3-Dehydro-2- Deoxy-D-Gluconate! + NADH. [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230 [H]