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The map label for this gene is yjjL [H]

Identifier: 167624011

GI number: 167624011

Start: 2512069

End: 2513448

Strand: Reverse

Name: yjjL [H]

Synonym: Shal_2087

Alternate gene names: 167624011

Gene position: 2513448-2512069 (Counterclockwise)

Preceding gene: 167624012

Following gene: 167624010

Centisome position: 48.09

GC content: 43.04

Gene sequence:

>1380_bases
GTGAATAAAATTGCTGACGGTAAACCAACACAGTGGCAGCGACATGGTCTGCTACTGCTGTTGACGTTGTTTTATGGTGA
AACGTTCATCGGAAGACAAATTATCGCAGTGATGATTGAGCCCATTAAATTGGAGTTTGGTACTAGCGATACACAAATGG
GTTTGATGTCTGGACTGGCTTTTGCTGTTGTATTTGCAGTGCTAGGCTTACCCGCGGGTCAGTTAGCAGATAAAAAGTCA
CGAACAAGAATATTGGCGTTTTGCGCCTTAGCTTGGGCATTTGCAACCGCGTTATGTGGGTTTGCTGTTGGCTTTTATAT
GTTGGTTGCGGCGCGGATGTTAGTCGCCGTGGCTGAAGTCCCTATAGGTTCCTCTTCAATGTCTCTTATCGCCGATTTAT
ATCCGTTAAATAAGCGTGCATTTGCCATTAGCTGTTATACCTCTGCCGCGACAATCGCCTCTATTTTGGCATTAGGCCTT
GGAGCTTACCTCATAGGTCAACTGGGGTGGCGACATACTTTTTTTCTGCTCTCTATTCCCGCTCTTATACTTTCTGCTGT
ATTTTTCATTTTCGTAAAAGAGCCGAAAAGAGGTCAATTCAATCACAAATCTCAAGCTAACCTAACCGCAGTACAAACAG
AACTAACCTCTAGCAACGGAACTTTAGCAGATACATTACGATCGCTGTGGGCACATAAACGATTTAAACTGCTCGTTTTT
TCAAGTGCGATGGCAACCATGTCAGCAAATGCGTTCGGCATGTGGAATATTACGTTCATAATGCGAAGCCACCAACTCGA
GTTATACAACGCAGGTTTGCTTGCAGGAGTTATCGGCGGAGGTTCTGCTGCAATCGGTATTCTTTTAGGCGGGTATTTAG
CAGATAAGCGCAGCGTTCGGACCTCACCGTTACAACTACCGATTATTGGCCATATACTTGGGGTCACCTCTCTGTACTTA
TATCTATTATGGCCAAGTGAGCAAACCATATTAATTTTTGGACATAACGTGCCAGTTGCGATGTTTGCTTGCGCCTTAAC
CAGTTTCTTTTCTGTATGGTGGGTTGGTCCCTGTTTTAGTTTGCTCACCAATTTAGTCCCAGCTCATCAAAGAGCTGTTG
CTATTGCATGTCAATCTATCTTAGTTTCGTTTCTCGGTATGGGAGTTGGCCCTGTTTTAGTCGGCAGCCTTAGTGATATT
TTGTCTCCTAGAATGGGCGAGGAATCATTGAGGTATGCACTAATTTTCAGTAGTTTTTCGACAATTATCGCCATATTCCT
TTTAATAAAGCTTAACCAAATATTTACAGCTAATGACCCTAACTATATTGACGTGAGTTCTTCGACTCAATCAAAGTTAA
ACCAAATTCACAGTGAATAG

Upstream 100 bases:

>100_bases
GAGATATATTGCTTGAGCTGGGTAGACGTGGCACTGTTGGCGGCCAAGAAGATATGATTGATGATACCGCAATGAATATG
GCAAGAGAGCTTGCCTAAAC

Downstream 100 bases:

>100_bases
ATCTAGTCTCTTTAAACGAGGAGACATAACTTATCACTCGGCATACTGGCTGTATCAAAATCTACCATCGCTTTAAAGTT
TACTTTTTAAGCGCTAAGTA

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MNKIADGKPTQWQRHGLLLLLTLFYGETFIGRQIIAVMIEPIKLEFGTSDTQMGLMSGLAFAVVFAVLGLPAGQLADKKS
RTRILAFCALAWAFATALCGFAVGFYMLVAARMLVAVAEVPIGSSSMSLIADLYPLNKRAFAISCYTSAATIASILALGL
GAYLIGQLGWRHTFFLLSIPALILSAVFFIFVKEPKRGQFNHKSQANLTAVQTELTSSNGTLADTLRSLWAHKRFKLLVF
SSAMATMSANAFGMWNITFIMRSHQLELYNAGLLAGVIGGGSAAIGILLGGYLADKRSVRTSPLQLPIIGHILGVTSLYL
YLLWPSEQTILIFGHNVPVAMFACALTSFFSVWWVGPCFSLLTNLVPAHQRAVAIACQSILVSFLGMGVGPVLVGSLSDI
LSPRMGEESLRYALIFSSFSTIIAIFLLIKLNQIFTANDPNYIDVSSSTQSKLNQIHSE

Sequences:

>Translated_459_residues
MNKIADGKPTQWQRHGLLLLLTLFYGETFIGRQIIAVMIEPIKLEFGTSDTQMGLMSGLAFAVVFAVLGLPAGQLADKKS
RTRILAFCALAWAFATALCGFAVGFYMLVAARMLVAVAEVPIGSSSMSLIADLYPLNKRAFAISCYTSAATIASILALGL
GAYLIGQLGWRHTFFLLSIPALILSAVFFIFVKEPKRGQFNHKSQANLTAVQTELTSSNGTLADTLRSLWAHKRFKLLVF
SSAMATMSANAFGMWNITFIMRSHQLELYNAGLLAGVIGGGSAAIGILLGGYLADKRSVRTSPLQLPIIGHILGVTSLYL
YLLWPSEQTILIFGHNVPVAMFACALTSFFSVWWVGPCFSLLTNLVPAHQRAVAIACQSILVSFLGMGVGPVLVGSLSDI
LSPRMGEESLRYALIFSSFSTIIAIFLLIKLNQIFTANDPNYIDVSSSTQSKLNQIHSE
>Mature_459_residues
MNKIADGKPTQWQRHGLLLLLTLFYGETFIGRQIIAVMIEPIKLEFGTSDTQMGLMSGLAFAVVFAVLGLPAGQLADKKS
RTRILAFCALAWAFATALCGFAVGFYMLVAARMLVAVAEVPIGSSSMSLIADLYPLNKRAFAISCYTSAATIASILALGL
GAYLIGQLGWRHTFFLLSIPALILSAVFFIFVKEPKRGQFNHKSQANLTAVQTELTSSNGTLADTLRSLWAHKRFKLLVF
SSAMATMSANAFGMWNITFIMRSHQLELYNAGLLAGVIGGGSAAIGILLGGYLADKRSVRTSPLQLPIIGHILGVTSLYL
YLLWPSEQTILIFGHNVPVAMFACALTSFFSVWWVGPCFSLLTNLVPAHQRAVAIACQSILVSFLGMGVGPVLVGSLSDI
LSPRMGEESLRYALIFSSFSTIIAIFLLIKLNQIFTANDPNYIDVSSSTQSKLNQIHSE

Specific function: Responsible for the transport of L-galactonate from the periplasm across the inner membrane (Probable). Is essential for growth on L-galactonate as the sole carbon source [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI185136021, Length=452, Percent_Identity=22.3451327433628, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI2367379, Length=290, Percent_Identity=21.7241379310345, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789152, Length=307, Percent_Identity=23.1270358306189, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI87082320, Length=297, Percent_Identity=22.8956228956229, Blast_Score=72, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24654037, Length=408, Percent_Identity=24.5098039215686, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24654041, Length=408, Percent_Identity=24.5098039215686, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49683; Mature: 49683

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKIADGKPTQWQRHGLLLLLTLFYGETFIGRQIIAVMIEPIKLEFGTSDTQMGLMSGLA
CCCCCCCCCCCHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHH
FAVVFAVLGLPAGQLADKKSRTRILAFCALAWAFATALCGFAVGFYMLVAARMLVAVAEV
HHHHHHHHCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PIGSSSMSLIADLYPLNKRAFAISCYTSAATIASILALGLGAYLIGQLGWRHTFFLLSIP
CCCCCHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
ALILSAVFFIFVKEPKRGQFNHKSQANLTAVQTELTSSNGTLADTLRSLWAHKRFKLLVF
HHHHHHHHHHHCCCCCCCCCCCCCCCCHHHEEEECCCCCCCHHHHHHHHHHHCHHEEEEE
SSAMATMSANAFGMWNITFIMRSHQLELYNAGLLAGVIGGGSAAIGILLGGYLADKRSVR
HHHHHHHCCCCCEEEEEEEEEECCCEEEECCCHHHHHHCCCHHHHHHHHHHHHHCCCCCC
TSPLQLPIIGHILGVTSLYLYLLWPSEQTILIFGHNVPVAMFACALTSFFSVWWVGPCFS
CCCCCCHHHHHHHHHHHHHEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
LLTNLVPAHQRAVAIACQSILVSFLGMGVGPVLVGSLSDILSPRMGEESLRYALIFSSFS
HHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
TIIAIFLLIKLNQIFTANDPNYIDVSSSTQSKLNQIHSE
HHHHHHHHHHHHHHEECCCCCEEECCCCHHHHHHHHCCC
>Mature Secondary Structure
MNKIADGKPTQWQRHGLLLLLTLFYGETFIGRQIIAVMIEPIKLEFGTSDTQMGLMSGLA
CCCCCCCCCCCHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHH
FAVVFAVLGLPAGQLADKKSRTRILAFCALAWAFATALCGFAVGFYMLVAARMLVAVAEV
HHHHHHHHCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PIGSSSMSLIADLYPLNKRAFAISCYTSAATIASILALGLGAYLIGQLGWRHTFFLLSIP
CCCCCHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
ALILSAVFFIFVKEPKRGQFNHKSQANLTAVQTELTSSNGTLADTLRSLWAHKRFKLLVF
HHHHHHHHHHHCCCCCCCCCCCCCCCCHHHEEEECCCCCCCHHHHHHHHHHHCHHEEEEE
SSAMATMSANAFGMWNITFIMRSHQLELYNAGLLAGVIGGGSAAIGILLGGYLADKRSVR
HHHHHHHCCCCCEEEEEEEEEECCCEEEECCCHHHHHHCCCHHHHHHHHHHHHHCCCCCC
TSPLQLPIIGHILGVTSLYLYLLWPSEQTILIFGHNVPVAMFACALTSFFSVWWVGPCFS
CCCCCCHHHHHHHHHHHHHEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
LLTNLVPAHQRAVAIACQSILVSFLGMGVGPVLVGSLSDILSPRMGEESLRYALIFSSFS
HHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
TIIAIFLLIKLNQIFTANDPNYIDVSSSTQSKLNQIHSE
HHHHHHHHHHHHHHEECCCCCEEECCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]