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The map label for this gene is ydhC [H]

Identifier: 167624009

GI number: 167624009

Start: 2509537

End: 2510769

Strand: Direct

Name: ydhC [H]

Synonym: Shal_2085

Alternate gene names: 167624009

Gene position: 2509537-2510769 (Clockwise)

Preceding gene: 167624002

Following gene: 167624016

Centisome position: 48.01

GC content: 41.04

Gene sequence:

>1233_bases
ATGAATCTTAAATACTATATATTTCTTACCTATCTAGCGTTACTAAGTATGCTAGGTTTTATTGCAACCGACATGTATTT
GCCTGCATTCAAAGCAATTGAAGACACAATGGCGGCGTCACCATCACAAGTCGCGATGTCTTTGACGTTCTTTTTAGCGG
GCTTGGCTCTGGGGCAATTGTTATACGGTCCATTAGTAGAACGCTTCGGTAAGCGTAACTCACTCATTTTTGGATTAGTA
TTATTTTCGGTTGCTAGTTTTTCACTGTCAATTAGTGACTCAATGTTAGTATTTAACATTTCACGCTTCATGCAAGCGTT
AGGTGCTTGTTCTGCTGGGGTTATTTGGCAAGCAATTGTTATCGAGAAGTATGATGCTTCAAAGGCGCAAAGTGTATTTT
CAAACATTATGCCGCTTGTGGCTTTATCGCCGGCTCTCGCTCCAATCTTAGGTGCATTTATTCTTGAATCTATGGGCTGG
GAAAGCATTTTCGTTACCCTAACTATGATGTCTGTTGTCATGATCTTATTGACGGTATGGTTTGTACCTAGTGAAACCAA
AGCGATAAATCGTAAAAAGAAAGATATTAGCTACGTTAATATCTTCAAGAACACCAAGTATTTGGGTAACGTTGTGATTT
TTGGTGCTTGTTCAGCGGCGTTCTTCTCTTACTTAACAGTTTGGCCAATGGTCATGGAGCAGCACGGTTTCGACGCAAAA
GCGATCGGTTTGAGCTTTATTCCACAAACTATCATGTTCGTTTTAGGTGGTTATGCAAGTAAGACTCTCATTCGTAAAGT
GGGTGCTGAAAACGCATTAAAGGTTTTGCTATCGGTATTTGGTCTATGTTCACTTGGTATTGTTGTCGTAACCATTTTGA
TTACTGGCTTGTCGGTATTCCCGCTGCTAGCGGTATTCTCGGTACTCGCTGCATGTAATGGTGCGATTTACCCAATCGTT
GTTAATGGTGCCTTGCAGCAGTTTCCTGAAAACGCAGCGAAAGCCGCTGGATTACAAAACTTTTTACAGATCAGCTTATC
TTTTGGTGCTTCAAGTTTAGTGGCTATTTGGGCAACAAGTGGTGAAGTTGCCATTGGTTGGGGCATCATGATCTGTTCGT
TTATTGTCTTTCTTGGCTACAAGCTACGTAATCACAATAACTGGAAAGAAGTTGGCGAAAATATTGTTATGCCAGATCCT
GCTCGCATCGCAATCAATCAGGACAAGAATTAG

Upstream 100 bases:

>100_bases
AGCTAATGTGAAAAATAAACGTTTCACAGTAGTTTAGCAAGTGTTTAAACTGCGCGACTTTAATAAATCCCGATTTAATT
CTTTGCTGGTGAATTCTCCT

Downstream 100 bases:

>100_bases
TCAAACTGCTTTGTTGTTGGTCAAAGTGATAAATTCTTAGAATTATTACTTTACAAGCACAATAGAGCGCTATATTATTC
GCGGCGTTCGGAGGGATGGC

Product: inner membrane transport protein YdhC

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MNLKYYIFLTYLALLSMLGFIATDMYLPAFKAIEDTMAASPSQVAMSLTFFLAGLALGQLLYGPLVERFGKRNSLIFGLV
LFSVASFSLSISDSMLVFNISRFMQALGACSAGVIWQAIVIEKYDASKAQSVFSNIMPLVALSPALAPILGAFILESMGW
ESIFVTLTMMSVVMILLTVWFVPSETKAINRKKKDISYVNIFKNTKYLGNVVIFGACSAAFFSYLTVWPMVMEQHGFDAK
AIGLSFIPQTIMFVLGGYASKTLIRKVGAENALKVLLSVFGLCSLGIVVVTILITGLSVFPLLAVFSVLAACNGAIYPIV
VNGALQQFPENAAKAAGLQNFLQISLSFGASSLVAIWATSGEVAIGWGIMICSFIVFLGYKLRNHNNWKEVGENIVMPDP
ARIAINQDKN

Sequences:

>Translated_410_residues
MNLKYYIFLTYLALLSMLGFIATDMYLPAFKAIEDTMAASPSQVAMSLTFFLAGLALGQLLYGPLVERFGKRNSLIFGLV
LFSVASFSLSISDSMLVFNISRFMQALGACSAGVIWQAIVIEKYDASKAQSVFSNIMPLVALSPALAPILGAFILESMGW
ESIFVTLTMMSVVMILLTVWFVPSETKAINRKKKDISYVNIFKNTKYLGNVVIFGACSAAFFSYLTVWPMVMEQHGFDAK
AIGLSFIPQTIMFVLGGYASKTLIRKVGAENALKVLLSVFGLCSLGIVVVTILITGLSVFPLLAVFSVLAACNGAIYPIV
VNGALQQFPENAAKAAGLQNFLQISLSFGASSLVAIWATSGEVAIGWGIMICSFIVFLGYKLRNHNNWKEVGENIVMPDP
ARIAINQDKN
>Mature_410_residues
MNLKYYIFLTYLALLSMLGFIATDMYLPAFKAIEDTMAASPSQVAMSLTFFLAGLALGQLLYGPLVERFGKRNSLIFGLV
LFSVASFSLSISDSMLVFNISRFMQALGACSAGVIWQAIVIEKYDASKAQSVFSNIMPLVALSPALAPILGAFILESMGW
ESIFVTLTMMSVVMILLTVWFVPSETKAINRKKKDISYVNIFKNTKYLGNVVIFGACSAAFFSYLTVWPMVMEQHGFDAK
AIGLSFIPQTIMFVLGGYASKTLIRKVGAENALKVLLSVFGLCSLGIVVVTILITGLSVFPLLAVFSVLAACNGAIYPIV
VNGALQQFPENAAKAAGLQNFLQISLSFGASSLVAIWATSGEVAIGWGIMICSFIVFLGYKLRNHNNWKEVGENIVMPDP
ARIAINQDKN

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Bcr/CmlA family [H]

Homologues:

Organism=Escherichia coli, GI48994889, Length=398, Percent_Identity=41.2060301507538, Blast_Score=291, Evalue=7e-80,
Organism=Escherichia coli, GI1788509, Length=381, Percent_Identity=23.6220472440945, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1790146, Length=218, Percent_Identity=29.3577981651376, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787065, Length=217, Percent_Identity=23.5023041474654, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790794, Length=229, Percent_Identity=24.0174672489083, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87082312, Length=360, Percent_Identity=22.2222222222222, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004812
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44513; Mature: 44513

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLKYYIFLTYLALLSMLGFIATDMYLPAFKAIEDTMAASPSQVAMSLTFFLAGLALGQL
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LYGPLVERFGKRNSLIFGLVLFSVASFSLSISDSMLVFNISRFMQALGACSAGVIWQAIV
HHHHHHHHHCCCCCHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
IEKYDASKAQSVFSNIMPLVALSPALAPILGAFILESMGWESIFVTLTMMSVVMILLTVW
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
FVPSETKAINRKKKDISYVNIFKNTKYLGNVVIFGACSAAFFSYLTVWPMVMEQHGFDAK
CCCCCHHHHHHHHHCCHHHHHHHCCHHHCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCHH
AIGLSFIPQTIMFVLGGYASKTLIRKVGAENALKVLLSVFGLCSLGIVVVTILITGLSVF
HHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLLAVFSVLAACNGAIYPIVVNGALQQFPENAAKAAGLQNFLQISLSFGASSLVAIWATS
HHHHHHHHHHHCCCCEEEEEECHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC
GEVAIGWGIMICSFIVFLGYKLRNHNNWKEVGENIVMPDPARIAINQDKN
CCEEHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCEEEECCCCC
>Mature Secondary Structure
MNLKYYIFLTYLALLSMLGFIATDMYLPAFKAIEDTMAASPSQVAMSLTFFLAGLALGQL
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LYGPLVERFGKRNSLIFGLVLFSVASFSLSISDSMLVFNISRFMQALGACSAGVIWQAIV
HHHHHHHHHCCCCCHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
IEKYDASKAQSVFSNIMPLVALSPALAPILGAFILESMGWESIFVTLTMMSVVMILLTVW
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
FVPSETKAINRKKKDISYVNIFKNTKYLGNVVIFGACSAAFFSYLTVWPMVMEQHGFDAK
CCCCCHHHHHHHHHCCHHHHHHHCCHHHCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCHH
AIGLSFIPQTIMFVLGGYASKTLIRKVGAENALKVLLSVFGLCSLGIVVVTILITGLSVF
HHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLLAVFSVLAACNGAIYPIVVNGALQQFPENAAKAAGLQNFLQISLSFGASSLVAIWATS
HHHHHHHHHHHCCCCEEEEEECHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC
GEVAIGWGIMICSFIVFLGYKLRNHNNWKEVGENIVMPDPARIAINQDKN
CCEEHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]