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The map label for this gene is apbE [H]

Identifier: 167623989

GI number: 167623989

Start: 2485625

End: 2486848

Strand: Reverse

Name: apbE [H]

Synonym: Shal_2063

Alternate gene names: 167623989

Gene position: 2486848-2485625 (Counterclockwise)

Preceding gene: 167623993

Following gene: 167623988

Centisome position: 47.58

GC content: 39.22

Gene sequence:

>1224_bases
ATGAAACGTATTTACCCACTCTTACTTTTACTGACATTTGCTAGCTACACCAGCGCAAAAAATGTAAATTCAGAATCTAC
AAACACGCTACTTACAAAATCAGAGCTTATTAAAAATCTGCCACCAGCACCTGACTTTAAGATTGTTAATGTCGATACTA
AAGGGGAACCCTATCTCTGTGAAGGTAACGCTATTATTACAGCTAGCAAGGGAGTAACAAACTTAACTACACTTAAATAC
TTTGGTACCTCAATCAGTATTGATGTTTATGATGCCGACAGCGACAATTTAAGACAGGCACTTTGTAACGCACTAAATGT
AATACAGGAGTACCATTATCTTGCGTCAAACTACAGTACCTATCCCCATGTCACCAATATCAAGACCATTAATAACGCCC
CAGAAAAGTCCCATCACATCGACCCAAAACTGACACAGCTCATTGATGCGAGCATTGAGTGGCATGACAAGACTGGCGGA
TATTTTAACATTGCCCTATCACCAGTCATTCAACTTTGGCGTGGCTACAGAGCACAATGCATAGGAGAACGTAAACTTCA
GGACAGATGCGAAATCCCGACTAACGCTGAATTAAATGCAGTCAGACCATTGATTAATATTGATAATATCAAATTAAATA
AAGAGCAAAATACCATACAGATGCAAACGGGCATGAGTATTGACCTTGGTGGAATAGCCAAAGGCTGGATGACGGAGAAA
GTTTACAGGCAGCTAAAAATGGATGGCATTGAAAACTTTATGATCAATGCGGGTGGCAATATTCGCCATTATGGGCTCCA
CCCACAAGGTCGCCAATTTACGACGGCTGTAGAAGACCCAATCTGCAAGAAATACAATAACAGCCTTAGTCAATGCCAAA
GCTTCGATGGCCAATATCATGAAGTGCTCACAGGTAAAGATATTGCTGTAGTATCGAGTGGTAACTACTTAAGATATTAT
CGAGTGAAGGGAAAAGAATACCACCATATTATTAACCCCAAGACCTTATACCCCAAGCGTATAGGCATATCCACGACCAT
TGTAATGAGTCGGGAACAAATTTATGCTGATATTATTTCAACAGCGTTATTTCTTATGCCGTTAGACGAGGCGTTAGATT
ATGTTAATAGTACCGACAATCTCGAAGCCGTTTGGTATTTAAATAAAGAGGGAGAAAAAACCAAAAGTGACAAACTTTTT
AAATTCAAAAAACACTTACAATAA

Upstream 100 bases:

>100_bases
TTTATTTATTTGACGCAGTTAACACAAACTACAGTTAATTATTACCGCACAAGCTGCTTATGATATTCATTTAAAAACTA
CGCGACCACCAGACTTTATT

Downstream 100 bases:

>100_bases
GCGATACAGTTATTTAAATGACGTCAAACGTAAAAAATTCGAGTTTAATTATATAATTCAAATTAGACCATGGACGGTTT
TATTTTAAATTATTAATAAA

Product: ApbE family lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MKRIYPLLLLLTFASYTSAKNVNSESTNTLLTKSELIKNLPPAPDFKIVNVDTKGEPYLCEGNAIITASKGVTNLTTLKY
FGTSISIDVYDADSDNLRQALCNALNVIQEYHYLASNYSTYPHVTNIKTINNAPEKSHHIDPKLTQLIDASIEWHDKTGG
YFNIALSPVIQLWRGYRAQCIGERKLQDRCEIPTNAELNAVRPLINIDNIKLNKEQNTIQMQTGMSIDLGGIAKGWMTEK
VYRQLKMDGIENFMINAGGNIRHYGLHPQGRQFTTAVEDPICKKYNNSLSQCQSFDGQYHEVLTGKDIAVVSSGNYLRYY
RVKGKEYHHIINPKTLYPKRIGISTTIVMSREQIYADIISTALFLMPLDEALDYVNSTDNLEAVWYLNKEGEKTKSDKLF
KFKKHLQ

Sequences:

>Translated_407_residues
MKRIYPLLLLLTFASYTSAKNVNSESTNTLLTKSELIKNLPPAPDFKIVNVDTKGEPYLCEGNAIITASKGVTNLTTLKY
FGTSISIDVYDADSDNLRQALCNALNVIQEYHYLASNYSTYPHVTNIKTINNAPEKSHHIDPKLTQLIDASIEWHDKTGG
YFNIALSPVIQLWRGYRAQCIGERKLQDRCEIPTNAELNAVRPLINIDNIKLNKEQNTIQMQTGMSIDLGGIAKGWMTEK
VYRQLKMDGIENFMINAGGNIRHYGLHPQGRQFTTAVEDPICKKYNNSLSQCQSFDGQYHEVLTGKDIAVVSSGNYLRYY
RVKGKEYHHIINPKTLYPKRIGISTTIVMSREQIYADIISTALFLMPLDEALDYVNSTDNLEAVWYLNKEGEKTKSDKLF
KFKKHLQ
>Mature_407_residues
MKRIYPLLLLLTFASYTSAKNVNSESTNTLLTKSELIKNLPPAPDFKIVNVDTKGEPYLCEGNAIITASKGVTNLTTLKY
FGTSISIDVYDADSDNLRQALCNALNVIQEYHYLASNYSTYPHVTNIKTINNAPEKSHHIDPKLTQLIDASIEWHDKTGG
YFNIALSPVIQLWRGYRAQCIGERKLQDRCEIPTNAELNAVRPLINIDNIKLNKEQNTIQMQTGMSIDLGGIAKGWMTEK
VYRQLKMDGIENFMINAGGNIRHYGLHPQGRQFTTAVEDPICKKYNNSLSQCQSFDGQYHEVLTGKDIAVVSSGNYLRYY
RVKGKEYHHIINPKTLYPKRIGISTTIVMSREQIYADIISTALFLMPLDEALDYVNSTDNLEAVWYLNKEGEKTKSDKLF
KFKKHLQ

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=292, Percent_Identity=21.5753424657534, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 46178; Mature: 46178

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRIYPLLLLLTFASYTSAKNVNSESTNTLLTKSELIKNLPPAPDFKIVNVDTKGEPYLC
CCHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEHHHHHHCCCCCCCEEEEEECCCCCCEEE
EGNAIITASKGVTNLTTLKYFGTSISIDVYDADSDNLRQALCNALNVIQEYHYLASNYST
CCCEEEEECCCCCCEEEEEEECCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCC
YPHVTNIKTINNAPEKSHHIDPKLTQLIDASIEWHDKTGGYFNIALSPVIQLWRGYRAQC
CCCCCCEEECCCCCCCCCCCCHHHHHHHHCCEEEECCCCCEEEEHHHHHHHHHHCHHHHH
IGERKLQDRCEIPTNAELNAVRPLINIDNIKLNKEQNTIQMQTGMSIDLGGIAKGWMTEK
HCHHHHHHHCCCCCCCCHHHHCCEEECCCEEECCCCCEEEEECCCEEECCCCCCHHHHHH
VYRQLKMDGIENFMINAGGNIRHYGLHPQGRQFTTAVEDPICKKYNNSLSQCQSFDGQYH
HHHHHHHCCCCEEEEECCCCEEEECCCCCCCEEEHHHCCHHHHHHCCHHHHHHHCCCCHH
EVLTGKDIAVVSSGNYLRYYRVKGKEYHHIINPKTLYPKRIGISTTIVMSREQIYADIIS
EEECCCCEEEEECCCEEEEEEECCCCEEEECCCCCCCCCCCCCEEEEEECHHHHHHHHHH
TALFLMPLDEALDYVNSTDNLEAVWYLNKEGEKTKSDKLFKFKKHLQ
HHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MKRIYPLLLLLTFASYTSAKNVNSESTNTLLTKSELIKNLPPAPDFKIVNVDTKGEPYLC
CCHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEHHHHHHCCCCCCCEEEEEECCCCCCEEE
EGNAIITASKGVTNLTTLKYFGTSISIDVYDADSDNLRQALCNALNVIQEYHYLASNYST
CCCEEEEECCCCCCEEEEEEECCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCC
YPHVTNIKTINNAPEKSHHIDPKLTQLIDASIEWHDKTGGYFNIALSPVIQLWRGYRAQC
CCCCCCEEECCCCCCCCCCCCHHHHHHHHCCEEEECCCCCEEEEHHHHHHHHHHCHHHHH
IGERKLQDRCEIPTNAELNAVRPLINIDNIKLNKEQNTIQMQTGMSIDLGGIAKGWMTEK
HCHHHHHHHCCCCCCCCHHHHCCEEECCCEEECCCCCEEEEECCCEEECCCCCCHHHHHH
VYRQLKMDGIENFMINAGGNIRHYGLHPQGRQFTTAVEDPICKKYNNSLSQCQSFDGQYH
HHHHHHHCCCCEEEEECCCCEEEECCCCCCCEEEHHHCCHHHHHHCCHHHHHHHCCCCHH
EVLTGKDIAVVSSGNYLRYYRVKGKEYHHIINPKTLYPKRIGISTTIVMSREQIYADIIS
EEECCCCEEEEECCCEEEEEEECCCCEEEECCCCCCCCCCCCCEEEEEECHHHHHHHHHH
TALFLMPLDEALDYVNSTDNLEAVWYLNKEGEKTKSDKLFKFKKHLQ
HHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]