Click here to switch to the map view.

The map label for this gene is aspC [H]

Identifier: 167623968

GI number: 167623968

Start: 2464385

End: 2465620

Strand: Reverse

Name: aspC [H]

Synonym: Shal_2042

Alternate gene names: 167623968

Gene position: 2465620-2464385 (Counterclockwise)

Preceding gene: 167623979

Following gene: 167623966

Centisome position: 47.17

GC content: 46.68

Gene sequence:

>1236_bases
ATGGCTGCTAAACAGCCAACAACAGAGAAGGTAAATGGAGCCATGTTCAACAAATTGACCGCTATGCCTGCCGATCCAAT
TCTTGGGTTACTGACTAAGTATCGTGAAGATGACCATTCTCAAAAAGTCGATTTGGGTGTGGGTGTCTATAAAGATGAGT
CGGGTCACACACCAATCCTGTCTTGCGTGAAAAAGGCAGAGAAGTTTAGGTTAGAGACAGAGTCAACCAAAGTTTACATC
GGCCCTACTGGTTCTGCCGACTTTAACCGCTTAATGTCTGAACTTGCTTTTGGCGCTGTTCACCCAGCAATTATCGCTAA
TCGAATTCGCACAGTTTCGACACCCGGTGGTACGGGAGCACTGCGTGTTGCGGCCGATTTTATCAAACGCTGTAACCCAA
ATGCGGTAATCTGGGTTAGCGATCCAACTTGGGCTAACCACACTGGATTATTTGAGGCGGCGGGCATTACCGTTAAAACC
TACCCCTACTATGACTACGAAACGAAATCGCTTAAGTTTGACGAGATGAAAGCGGCGCTAGCAAACGTTAGCTCTGACGA
TGTCGTCCTTCTACATGCATGTTGTCATAACCCAAGTGGCATGGACTTAAGCGTCCCACAATGGGACGAGATCATCACCC
TCACAGCCGATAAGGGGTTTACACCACTAATTGATATGGCTTACCAAGGTTTTGGTGACGGTGTAGATGAAGATGCTTAT
GGCGTACGTAAGATGGCAGCAGCAGTCAACGATATGATCCTGTGCAGCTCTTGCTCGAAGAACTTTGGTTTATACCGCGA
GCGTATCGGCGCATGCACGATAATTGCTAAGGATGCGACTCGTGCTGATATCGCGTTTTCAGTACTCTTGTACGTGATAC
GTTGTATCTACTCAATGCCACCAGCTCATGGCGCCGCCATTGTCGAAACTATACTTGGTTCAGATGAGCTAAAACAGGAA
TGGTTAGACGAACTAACCGTGATGCGAGAGCGCATTAACGGTAACCGTACAATGTTAGTTAATAAGCTGAAAGAGAAAGG
CGTACAACGCAACTTTGACTTTATCGCCCAGCAGAAAGGCATGTTCTCTTTCCTTGGGATCACAGCAGCACAGGTTGCCG
AGCTGCAGGAGCATTATAGTGTTTACATGGTGGACTCAAGCCGTATTAGTATCGCAGGTATTGGAACCGGTAATGTCGAT
TACTTAGCAGAATCGATTGCTAAAGTGATCTCTTAA

Upstream 100 bases:

>100_bases
GATGTGGGATCAATATTTTCAAACAAGTTTCAGCATCAAAGTGAACTGCAATGCTGTTCAGTGTTAGGTTATATACGTTA
CTCTAAGTGAATAAAGATAA

Downstream 100 bases:

>100_bases
AAAAATCTGTCACTCTAATATTCCGTACACGACTTAAAAATTAAAAAGCCGATAATAGAAATATTATCGGCTTTTTCGTC
TCAATATTGAGGTTCGATGC

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MAAKQPTTEKVNGAMFNKLTAMPADPILGLLTKYREDDHSQKVDLGVGVYKDESGHTPILSCVKKAEKFRLETESTKVYI
GPTGSADFNRLMSELAFGAVHPAIIANRIRTVSTPGGTGALRVAADFIKRCNPNAVIWVSDPTWANHTGLFEAAGITVKT
YPYYDYETKSLKFDEMKAALANVSSDDVVLLHACCHNPSGMDLSVPQWDEIITLTADKGFTPLIDMAYQGFGDGVDEDAY
GVRKMAAAVNDMILCSSCSKNFGLYRERIGACTIIAKDATRADIAFSVLLYVIRCIYSMPPAHGAAIVETILGSDELKQE
WLDELTVMRERINGNRTMLVNKLKEKGVQRNFDFIAQQKGMFSFLGITAAQVAELQEHYSVYMVDSSRISIAGIGTGNVD
YLAESIAKVIS

Sequences:

>Translated_411_residues
MAAKQPTTEKVNGAMFNKLTAMPADPILGLLTKYREDDHSQKVDLGVGVYKDESGHTPILSCVKKAEKFRLETESTKVYI
GPTGSADFNRLMSELAFGAVHPAIIANRIRTVSTPGGTGALRVAADFIKRCNPNAVIWVSDPTWANHTGLFEAAGITVKT
YPYYDYETKSLKFDEMKAALANVSSDDVVLLHACCHNPSGMDLSVPQWDEIITLTADKGFTPLIDMAYQGFGDGVDEDAY
GVRKMAAAVNDMILCSSCSKNFGLYRERIGACTIIAKDATRADIAFSVLLYVIRCIYSMPPAHGAAIVETILGSDELKQE
WLDELTVMRERINGNRTMLVNKLKEKGVQRNFDFIAQQKGMFSFLGITAAQVAELQEHYSVYMVDSSRISIAGIGTGNVD
YLAESIAKVIS
>Mature_410_residues
AAKQPTTEKVNGAMFNKLTAMPADPILGLLTKYREDDHSQKVDLGVGVYKDESGHTPILSCVKKAEKFRLETESTKVYIG
PTGSADFNRLMSELAFGAVHPAIIANRIRTVSTPGGTGALRVAADFIKRCNPNAVIWVSDPTWANHTGLFEAAGITVKTY
PYYDYETKSLKFDEMKAALANVSSDDVVLLHACCHNPSGMDLSVPQWDEIITLTADKGFTPLIDMAYQGFGDGVDEDAYG
VRKMAAAVNDMILCSSCSKNFGLYRERIGACTIIAKDATRADIAFSVLLYVIRCIYSMPPAHGAAIVETILGSDELKQEW
LDELTVMRERINGNRTMLVNKLKEKGVQRNFDFIAQQKGMFSFLGITAAQVAELQEHYSVYMVDSSRISIAGIGTGNVDY
LAESIAKVIS

Specific function: Unknown

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=390, Percent_Identity=41.2820512820513, Blast_Score=304, Evalue=1e-82,
Organism=Homo sapiens, GI4504067, Length=398, Percent_Identity=36.4321608040201, Blast_Score=266, Evalue=4e-71,
Organism=Homo sapiens, GI117414139, Length=388, Percent_Identity=23.9690721649485, Blast_Score=131, Evalue=9e-31,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=50, Blast_Score=419, Evalue=1e-118,
Organism=Escherichia coli, GI1790488, Length=397, Percent_Identity=41.3098236775819, Blast_Score=345, Evalue=4e-96,
Organism=Caenorhabditis elegans, GI71981858, Length=398, Percent_Identity=39.6984924623116, Blast_Score=306, Evalue=1e-83,
Organism=Caenorhabditis elegans, GI25147133, Length=390, Percent_Identity=39.7435897435897, Blast_Score=295, Evalue=4e-80,
Organism=Caenorhabditis elegans, GI17569539, Length=395, Percent_Identity=33.9240506329114, Blast_Score=244, Evalue=8e-65,
Organism=Caenorhabditis elegans, GI17569537, Length=387, Percent_Identity=28.9405684754522, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI25147136, Length=206, Percent_Identity=37.378640776699, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17550384, Length=267, Percent_Identity=29.2134831460674, Blast_Score=143, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6323055, Length=409, Percent_Identity=37.4083129584352, Blast_Score=291, Evalue=9e-80,
Organism=Saccharomyces cerevisiae, GI6322743, Length=424, Percent_Identity=33.4905660377358, Blast_Score=228, Evalue=1e-60,
Organism=Drosophila melanogaster, GI24580970, Length=406, Percent_Identity=38.6699507389163, Blast_Score=295, Evalue=3e-80,
Organism=Drosophila melanogaster, GI24580972, Length=396, Percent_Identity=39.3939393939394, Blast_Score=293, Evalue=1e-79,
Organism=Drosophila melanogaster, GI19920542, Length=389, Percent_Identity=39.8457583547558, Blast_Score=292, Evalue=3e-79,
Organism=Drosophila melanogaster, GI24654046, Length=392, Percent_Identity=38.5204081632653, Blast_Score=281, Evalue=6e-76,
Organism=Drosophila melanogaster, GI19922362, Length=392, Percent_Identity=38.5204081632653, Blast_Score=281, Evalue=6e-76,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 44973; Mature: 44842

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAKQPTTEKVNGAMFNKLTAMPADPILGLLTKYREDDHSQKVDLGVGVYKDESGHTPIL
CCCCCCCHHHHCHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEEECEEEEECCCCCCHHH
SCVKKAEKFRLETESTKVYIGPTGSADFNRLMSELAFGAVHPAIIANRIRTVSTPGGTGA
HHHHHHHHHEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCH
LRVAADFIKRCNPNAVIWVSDPTWANHTGLFEAAGITVKTYPYYDYETKSLKFDEMKAAL
HHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEECCEEEEECCCCCCCCCCCCHHHHHHHH
ANVSSDDVVLLHACCHNPSGMDLSVPQWDEIITLTADKGFTPLIDMAYQGFGDGVDEDAY
HCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCHHH
GVRKMAAAVNDMILCSSCSKNFGLYRERIGACTIIAKDATRADIAFSVLLYVIRCIYSMP
HHHHHHHHHHHHHEECCCCCCCCHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCC
PAHGAAIVETILGSDELKQEWLDELTVMRERINGNRTMLVNKLKEKGVQRNFDFIAQQKG
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHCC
MFSFLGITAAQVAELQEHYSVYMVDSSRISIAGIGTGNVDYLAESIAKVIS
CHHHHHHHHHHHHHHHHCCEEEEEECCEEEEEECCCCCHHHHHHHHHHHHC
>Mature Secondary Structure 
AAKQPTTEKVNGAMFNKLTAMPADPILGLLTKYREDDHSQKVDLGVGVYKDESGHTPIL
CCCCCCHHHHCHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEEECEEEEECCCCCCHHH
SCVKKAEKFRLETESTKVYIGPTGSADFNRLMSELAFGAVHPAIIANRIRTVSTPGGTGA
HHHHHHHHHEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCH
LRVAADFIKRCNPNAVIWVSDPTWANHTGLFEAAGITVKTYPYYDYETKSLKFDEMKAAL
HHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEECCEEEEECCCCCCCCCCCCHHHHHHHH
ANVSSDDVVLLHACCHNPSGMDLSVPQWDEIITLTADKGFTPLIDMAYQGFGDGVDEDAY
HCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCHHH
GVRKMAAAVNDMILCSSCSKNFGLYRERIGACTIIAKDATRADIAFSVLLYVIRCIYSMP
HHHHHHHHHHHHHEECCCCCCCCHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCC
PAHGAAIVETILGSDELKQEWLDELTVMRERINGNRTMLVNKLKEKGVQRNFDFIAQQKG
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHCC
MFSFLGITAAQVAELQEHYSVYMVDSSRISIAGIGTGNVDYLAESIAKVIS
CHHHHHHHHHHHHHHHHCCEEEEEECCEEEEEECCCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6378205; 3897210; 3521591; 3298240; 8905232; 9278503; 9298646; 1868057; 2007566; 2513875; 1993208; 9891001 [H]