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The map label for this gene is trxB [H]

Identifier: 167623950

GI number: 167623950

Start: 2440827

End: 2441780

Strand: Reverse

Name: trxB [H]

Synonym: Shal_2024

Alternate gene names: 167623950

Gene position: 2441780-2440827 (Counterclockwise)

Preceding gene: 167623954

Following gene: 167623945

Centisome position: 46.72

GC content: 45.28

Gene sequence:

>954_bases
ATGACCCAAGCTAGACATTGTGAACTACTTATTCTGGGTTCTGGCCCAGCAGGCTACACCGCTGCAGTTTATGCCGCTCG
CGCAAATTTAAAGCCTGTATTGATCACAGGTATTCAGCAAGGTGGACAATTAACCACCACGACTGAAGTTGAAAACTGGC
CAGGCGATGCAGAAGATCTTACCGGTCCTGCACTAATGGAGCGTATGCAAAAGCATGCAGAGAAGTTTGAAACAGAGATC
ATTTTTGATCACATTAACGAAGTTAACTTAAACGTGCGCCCTTTTAAGCTTAAAGGTGACAACGGTGAGTTCACCTGTGA
CTCTCTAATCATCTCTACTGGCGCATCAGCCATGTATTTAGGTCTGGAGTCTGAAGAAGCGTTTAAAGGCCGCGGCGTAT
CAGCTTGTGCTACTTGTGATGGATTCTTCTACCGTAACCAAAAAGTTGCTGTCATTGGTGGTGGTAACACCGCTGTTGAA
GAAGCACTTTACCTAAGTAACATCGCATCTGAAGTTCACCTTATTCACCGCCGCGATAGTTTCCGCAGTGAAAAAATCTT
AACTAAGCGCCTAATGGACAAAGTTGAGAGCGGCAACATCATTCTACATTTAGATAATACGCTTGATGAAGTTGTTGGCG
ATCAAATGGGTGTGACAGGCCTTAAGATGAAGAGCACCAAAGACGACAGCATCACAGATCTTGAAGTTGCGGGTGTATTC
GTAGCTATCGGCCATAAGCCAAACACCGAAATGTTTGAAGGCCAACTAGAGATGAACAATGGCTACATCAAAGTTCAAAG
TGGTCTCGATGGTAATGCCACACAAACTAGCATCGAAGGTGTATTTGCTGCAGGCGATGTCATGGATCAACATTACCGCC
AAGCTATTACCTCTGCAGGTACTGGCTGTATGGCAGCATTAGATGCAGAGCGTTTCCTAGACGCGAAGAACTAA

Upstream 100 bases:

>100_bases
ACCGATCACCTTAAATTCCATACAATCTGTCCAATTTCGTGAAACAAGCGGGAAGCGATCCCCCTTGCTATCCCGCATTC
GTTAAAGAACGGAGAAACTA

Downstream 100 bases:

>100_bases
TCAACTTAGATAGATTACGGCAACGTTAAAAAGCAGGCATTAGCCTGCTTTTTTTGTCGCTATCTTTTGCCCAAATAATA
CCAATTGCATTAAGTATCTG

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MTQARHCELLILGSGPAGYTAAVYAARANLKPVLITGIQQGGQLTTTTEVENWPGDAEDLTGPALMERMQKHAEKFETEI
IFDHINEVNLNVRPFKLKGDNGEFTCDSLIISTGASAMYLGLESEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVE
EALYLSNIASEVHLIHRRDSFRSEKILTKRLMDKVESGNIILHLDNTLDEVVGDQMGVTGLKMKSTKDDSITDLEVAGVF
VAIGHKPNTEMFEGQLEMNNGYIKVQSGLDGNATQTSIEGVFAAGDVMDQHYRQAITSAGTGCMAALDAERFLDAKN

Sequences:

>Translated_317_residues
MTQARHCELLILGSGPAGYTAAVYAARANLKPVLITGIQQGGQLTTTTEVENWPGDAEDLTGPALMERMQKHAEKFETEI
IFDHINEVNLNVRPFKLKGDNGEFTCDSLIISTGASAMYLGLESEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVE
EALYLSNIASEVHLIHRRDSFRSEKILTKRLMDKVESGNIILHLDNTLDEVVGDQMGVTGLKMKSTKDDSITDLEVAGVF
VAIGHKPNTEMFEGQLEMNNGYIKVQSGLDGNATQTSIEGVFAAGDVMDQHYRQAITSAGTGCMAALDAERFLDAKN
>Mature_316_residues
TQARHCELLILGSGPAGYTAAVYAARANLKPVLITGIQQGGQLTTTTEVENWPGDAEDLTGPALMERMQKHAEKFETEII
FDHINEVNLNVRPFKLKGDNGEFTCDSLIISTGASAMYLGLESEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVEE
ALYLSNIASEVHLIHRRDSFRSEKILTKRLMDKVESGNIILHLDNTLDEVVGDQMGVTGLKMKSTKDDSITDLEVAGVFV
AIGHKPNTEMFEGQLEMNNGYIKVQSGLDGNATQTSIEGVFAAGDVMDQHYRQAITSAGTGCMAALDAERFLDAKN

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=315, Percent_Identity=80.9523809523809, Blast_Score=535, Evalue=1e-153,
Organism=Escherichia coli, GI87081763, Length=315, Percent_Identity=32.0634920634921, Blast_Score=134, Evalue=6e-33,
Organism=Saccharomyces cerevisiae, GI6321898, Length=328, Percent_Identity=46.0365853658537, Blast_Score=282, Evalue=6e-77,
Organism=Saccharomyces cerevisiae, GI6320560, Length=321, Percent_Identity=47.3520249221184, Blast_Score=276, Evalue=3e-75,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34319; Mature: 34188

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQARHCELLILGSGPAGYTAAVYAARANLKPVLITGIQQGGQLTTTTEVENWPGDAEDL
CCCCCEEEEEEEECCCCCCHHEEEEHHCCCCEEEEEEECCCCEEEEEEECCCCCCCHHHC
TGPALMERMQKHAEKFETEIIFDHINEVNLNVRPFKLKGDNGEFTCDSLIISTGASAMYL
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCEEEHEEEEECCCCEEEE
GLESEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVEEALYLSNIASEVHLIHRRDS
ECCCCHHHCCCCCEEEEECCCEEEECCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCC
FRSEKILTKRLMDKVESGNIILHLDNTLDEVVGDQMGVTGLKMKSTKDDSITDLEVAGVF
HHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHCCCCCCCCEEECCCCCCCCCEEEEEEEE
VAIGHKPNTEMFEGQLEMNNGYIKVQSGLDGNATQTSIEGVFAAGDVMDQHYRQAITSAG
EEECCCCCCCCEECEEEECCCEEEEECCCCCCCCHHHHCEEEEHHHHHHHHHHHHHHHCC
TGCMAALDAERFLDAKN
CCCEEHHCHHHHHCCCC
>Mature Secondary Structure 
TQARHCELLILGSGPAGYTAAVYAARANLKPVLITGIQQGGQLTTTTEVENWPGDAEDL
CCCCEEEEEEEECCCCCCHHEEEEHHCCCCEEEEEEECCCCEEEEEEECCCCCCCHHHC
TGPALMERMQKHAEKFETEIIFDHINEVNLNVRPFKLKGDNGEFTCDSLIISTGASAMYL
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCEEEHEEEEECCCCEEEE
GLESEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVEEALYLSNIASEVHLIHRRDS
ECCCCHHHCCCCCEEEEECCCEEEECCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCC
FRSEKILTKRLMDKVESGNIILHLDNTLDEVVGDQMGVTGLKMKSTKDDSITDLEVAGVF
HHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHCCCCCCCCEEECCCCCCCCCEEEEEEEE
VAIGHKPNTEMFEGQLEMNNGYIKVQSGLDGNATQTSIEGVFAAGDVMDQHYRQAITSAG
EEECCCCCCCCEECEEEECCCEEEEECCCCCCCCHHHHCEEEEHHHHHHHHHHHHHHHCC
TGCMAALDAERFLDAKN
CCCEEHHCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]