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The map label for this gene is purC

Identifier: 167623746

GI number: 167623746

Start: 2172758

End: 2173861

Strand: Reverse

Name: purC

Synonym: Shal_1816

Alternate gene names: 167623746

Gene position: 2173861-2172758 (Counterclockwise)

Preceding gene: 167623747

Following gene: 167623741

Centisome position: 41.59

GC content: 43.39

Gene sequence:

>1104_bases
ATGAATCTTGCAGATAAAGTTTTAGTCGTAAATGACAACCTCCCAATTCGTACCAATAAACCTGTTCACTCAGGCAAGGT
CCGCAGTGTTTACTGGTTAACCGAAGAAGATAGCGCTCGGTTAATTAAAGATAAAGGTTACGATGTGCCAGCCGATGCAC
CGCTAGCCATTATGGTCATCAGCGATCGCATCTCCGCATTTGATTGTGTATGGCAAGGTGAGAACGGCTTAAATGGCGTT
CCAGGTAAAGGTACGGCACTTAATGCTATCTCAAACCATTGGTTTAAACTTTTCAAAGATAAAGGCCTTGCCGATAGCCA
TATCTTAGACATCCCTCACCCATTGGTGTGGATTGTACAAAAAGCACGTCCAGTAATGATTGAAGCGATTGCACGTCAAT
ACATTACCGGTTCAATGTGGCGTTCATACACAAAAGGTGAGCGTGAGTTTTGTGGGATCACAATCCCTGAAGGCTTAGAG
AAAGATCAAAAGCTACCAGAGCTATTAATCACCCCTTCAACAAAAGGCGTATTAACGGGTCTGGAAGGCGTACCAGAAGC
CGATGACGTTAACGTCTCTCGCAGCGATATTGAGCGCCACGTTGAAGGTTTTAACTTTACTAAGCTTGCAGACATTGATC
TTTATGAAAAGCTGCTTAAAGAAGGCTTCGATGTGATTAGTGACGCACTCGCTGAACACGATCAGGTTTTTGTTGATACC
AAATTTGAATTTGGCTATGTCAACGACGCTGCAGGTAATGAAAAGCTCATCTATATGGATGAAGTCGGCACCCCTGATAG
CTCACGTATTTGGGATGGTTCATCGCACCGTGATGGCAAGATCATCGAGCAATCTAAAGAGGGCTTCAGACAGTGGCTGC
TTAACCACTTCCCAGACTCTGATATCTTGCTAAACAAGAACCGTATGGAAGAGCGTTTTGCGCTAGCTAGAGATAATAAG
TTACCTGAATCAGTAATGATGGATATCTCTAATACCTATGTAGGGATTGCTGAAAAAGTCATTGGTAGCAAACTCAAGAT
CAGCGAAAACCCTAAGCAAGAGATCATCGATATCTTGCGCGAAGAATATCAGCTAATCGTTTAG

Upstream 100 bases:

>100_bases
TATAGTGAGTAAAACCCTTATTGCTAGGGTGTTGCAATAGGTAACTTCTGGTACAATCGCGCCACTAAAATTAAGCTTCT
CTATAATAAAAGTGTGCCCT

Downstream 100 bases:

>100_bases
CCGCTAAACAATTGCCATAGAAAAGCCGCAATATCCATTGCGGCTTTTTTGTGGAGCAACATCTATTCAGTAAAAATCCA
TTAGCGAGCGATAGATTTTC

Product: phosphoribosylaminoimidazole-succinocarboxamide synthase

Products: NA

Alternate protein names: SAICAR synthetase

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MNLADKVLVVNDNLPIRTNKPVHSGKVRSVYWLTEEDSARLIKDKGYDVPADAPLAIMVISDRISAFDCVWQGENGLNGV
PGKGTALNAISNHWFKLFKDKGLADSHILDIPHPLVWIVQKARPVMIEAIARQYITGSMWRSYTKGEREFCGITIPEGLE
KDQKLPELLITPSTKGVLTGLEGVPEADDVNVSRSDIERHVEGFNFTKLADIDLYEKLLKEGFDVISDALAEHDQVFVDT
KFEFGYVNDAAGNEKLIYMDEVGTPDSSRIWDGSSHRDGKIIEQSKEGFRQWLLNHFPDSDILLNKNRMEERFALARDNK
LPESVMMDISNTYVGIAEKVIGSKLKISENPKQEIIDILREEYQLIV

Sequences:

>Translated_367_residues
MNLADKVLVVNDNLPIRTNKPVHSGKVRSVYWLTEEDSARLIKDKGYDVPADAPLAIMVISDRISAFDCVWQGENGLNGV
PGKGTALNAISNHWFKLFKDKGLADSHILDIPHPLVWIVQKARPVMIEAIARQYITGSMWRSYTKGEREFCGITIPEGLE
KDQKLPELLITPSTKGVLTGLEGVPEADDVNVSRSDIERHVEGFNFTKLADIDLYEKLLKEGFDVISDALAEHDQVFVDT
KFEFGYVNDAAGNEKLIYMDEVGTPDSSRIWDGSSHRDGKIIEQSKEGFRQWLLNHFPDSDILLNKNRMEERFALARDNK
LPESVMMDISNTYVGIAEKVIGSKLKISENPKQEIIDILREEYQLIV
>Mature_367_residues
MNLADKVLVVNDNLPIRTNKPVHSGKVRSVYWLTEEDSARLIKDKGYDVPADAPLAIMVISDRISAFDCVWQGENGLNGV
PGKGTALNAISNHWFKLFKDKGLADSHILDIPHPLVWIVQKARPVMIEAIARQYITGSMWRSYTKGEREFCGITIPEGLE
KDQKLPELLITPSTKGVLTGLEGVPEADDVNVSRSDIERHVEGFNFTKLADIDLYEKLLKEGFDVISDALAEHDQVFVDT
KFEFGYVNDAAGNEKLIYMDEVGTPDSSRIWDGSSHRDGKIIEQSKEGFRQWLLNHFPDSDILLNKNRMEERFALARDNK
LPESVMMDISNTYVGIAEKVIGSKLKISENPKQEIIDILREEYQLIV

Specific function: Unknown

COG id: COG0152

COG function: function code F; Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SAICAR synthetase family

Homologues:

Organism=Saccharomyces cerevisiae, GI6319326, Length=346, Percent_Identity=28.9017341040462, Blast_Score=109, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PUR7_SHEHH (B0TQY6)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001674040.1
- ProteinModelPortal:   B0TQY6
- SMR:   B0TQY6
- GeneID:   5904392
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_1816
- HOGENOM:   HBG555040
- OMA:   SSRIWDG
- ProtClustDB:   PRK13960
- BioCyc:   SHAL458817:SHAL_1816-MONOMER
- HAMAP:   MF_00137
- InterPro:   IPR013816
- InterPro:   IPR014106
- InterPro:   IPR001636
- Gene3D:   G3DSA:3.30.470.20
- PANTHER:   PTHR11609
- TIGRFAMs:   TIGR02735

Pfam domain/function: PF01259 SAICAR_synt

EC number: =6.3.2.6

Molecular weight: Translated: 41401; Mature: 41401

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS01057 SAICAR_SYNTHETASE_1; PS01058 SAICAR_SYNTHETASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLADKVLVVNDNLPIRTNKPVHSGKVRSVYWLTEEDSARLIKDKGYDVPADAPLAIMVI
CCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHCCCCCCCCCCCEEEEEE
SDRISAFDCVWQGENGLNGVPGKGTALNAISNHWFKLFKDKGLADSHILDIPHPLVWIVQ
ECCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEECCCCHHHHHHH
KARPVMIEAIARQYITGSMWRSYTKGEREFCGITIPEGLEKDQKLPELLITPSTKGVLTG
HCCHHHHHHHHHHHHHHHHHHHHCCCCHHEECEECCCCCCCHHCCCCEEECCCCCHHHCC
LEGVPEADDVNVSRSDIERHVEGFNFTKLADIDLYEKLLKEGFDVISDALAEHDQVFVDT
CCCCCCCCCCCCCHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
KFEFGYVNDAAGNEKLIYMDEVGTPDSSRIWDGSSHRDGKIIEQSKEGFRQWLLNHFPDS
EEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
DILLNKNRMEERFALARDNKLPESVMMDISNTYVGIAEKVIGSKLKISENPKQEIIDILR
CEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHH
EEYQLIV
HHHHCCC
>Mature Secondary Structure
MNLADKVLVVNDNLPIRTNKPVHSGKVRSVYWLTEEDSARLIKDKGYDVPADAPLAIMVI
CCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHCCCCCCCCCCCEEEEEE
SDRISAFDCVWQGENGLNGVPGKGTALNAISNHWFKLFKDKGLADSHILDIPHPLVWIVQ
ECCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEECCCCHHHHHHH
KARPVMIEAIARQYITGSMWRSYTKGEREFCGITIPEGLEKDQKLPELLITPSTKGVLTG
HCCHHHHHHHHHHHHHHHHHHHHCCCCHHEECEECCCCCCCHHCCCCEEECCCCCHHHCC
LEGVPEADDVNVSRSDIERHVEGFNFTKLADIDLYEKLLKEGFDVISDALAEHDQVFVDT
CCCCCCCCCCCCCHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
KFEFGYVNDAAGNEKLIYMDEVGTPDSSRIWDGSSHRDGKIIEQSKEGFRQWLLNHFPDS
EEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
DILLNKNRMEERFALARDNKLPESVMMDISNTYVGIAEKVIGSKLKISENPKQEIIDILR
CEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHH
EEYQLIV
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA