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The map label for this gene is chvG [H]

Identifier: 167623664

GI number: 167623664

Start: 2076947

End: 2079130

Strand: Reverse

Name: chvG [H]

Synonym: Shal_1733

Alternate gene names: 167623664

Gene position: 2079130-2076947 (Counterclockwise)

Preceding gene: 167623665

Following gene: 167623663

Centisome position: 39.78

GC content: 46.2

Gene sequence:

>2184_bases
ATGTTTAATTTGCCAATCGGGCTGCGCACTAAAGTCGCAGTATTGTCTTTGTTCTTACTCTGCTTACCTTGGTTAGGTTA
TCAGTACGTGTGGGAGATGGAGAAATACCTGCGCCACGGCCAAGAGAAAACCTTAGAAGGCACAACCCAAGCACTGGCAA
CCGCCCTGCACGAAAGACCAAAACTCTTTGATAGCCAAGCAAGCTTTTTAACTCAGGTTGAAAAGGGCCGCGATCTGTAC
GCTTACCCACTTTCAGGGCCTATTCAACTCGACGGTAAACTGGCGGATTGGAGTAGCTATCGCCATCGTGCACTTAATTA
CGGCGATGATTATCAAATCTATAAACGTAATGAAAACCAGCCGTTAAACCTCAGCTTTACCCATATGGTAGGCAAATACG
CCGGCTATCTGTACGCCTTTTTCGAAGTTAGCGATCCACACGTTGTTTACCGCGGAAAAAACAGTCTTAGCATAGATAAT
AACGATCATATTGCCATCGCTACACTCGCACCCGATGGCAAGTTTCGCCGTTATATTGTTGCAACCACACAAGATGGCTG
GATAAGCGCCTTCGAACTGCCTGAAGATCCTAGCCTTTCAACCCCTGTAACACCGGAAGTTAAAATTCAGGGTAAGTGGA
CCAAGAGTAAACAAGGCTACAATGTCGAACTCAGGATCCCGCTTAATATGGTCGGCAGTAAACTCGGCTTTGCCGTTTAT
GACGTAAACGATAAAAAAAGCCGCGTATTAGATGCCGTGGTCGGTACCTCAGCAATCGATGATGTCAGCAAGCTGGGCAC
CGTACTTGTCCCCTCACCTGAAATCGAAAGTATTATTAAAGGCATGAGCCATAATAGCTCTCGTATTTGGGTGGTCGATA
AACACGGCCGCGTATTAGCAAAGTCCGGCGATATTCGCTCAGATAATAGCGTCTGGTCACGTGCTAATGTCGATAACGAT
GACAACTCTGGCTGGGAGCAATTCAAACATAAATACTTGCATCCGCTTTACTACAAAATTCTGACCACACCAGCTAAAGA
CTTTATCGATTCCTTGCAAGACTCCACTGTGTTGCAAGGGAGTCATATCTCTAAAGCCTTAAACGGCGAGCAAGGCTCAA
CGTGGCGCTTAACCCCCGACAACAAAGCGGTGGTGCTCGCGGCCGCTAGCCCTATTTGGATTGATGATAAAGTGATGGGA
GTGGTGATTGCCGAAGAAACCACTCACGGCATTCGAACCTTAAGAAACAAAGCCTTAGAAAAGCTGTTTAACGTGATTTT
AACCATCATGAGTATGGGCACCTTAGCGCTATTTTTCTTTGCTTCGAATATCTCAAGCCGTATTCGCAAATTGCGTGACG
AAGCCGAGCAAGCGATCGATAGCCAAGGGCGAATAAAAAATGAAATTCAGGGCTCTAAAGTCCGTGATGAGATCGGCGAT
CTATCGCGAAGTTTCGCCAGTATCGTTAGCCGCTTAAGCCAATATACTCATTACTTAGAAAACATGTCTTCGCGTTTATC
TCACGAGCTGCGCACCCCCGTTGCAGTGGTGCGCTCATCGCTAGAGCATCTTGGCCTGCAACAGCTTAGCCCCGATAGTC
GCAAATATGTTGACCGGGCACAAGAAGGCGTTAATCGCCTGAATATGATCTTAAACAATATGAGCGAAGCCACTCGTTTA
GAAGCAAGCTTATCTCATGCCGACACTACTGTTTTTCCGCTAGAAAAAGTCATCAACGGCTGCATGCAGGGCTATCAAAT
GACCTACCCCAATCAAGCATTTGAGCTCGATATTACCCAAGAGAGTATTGCGGTATTAGGGGTGCCTGAATATATCGCCC
AGCTAATGGATAAACTCATCGCTAACGCCCAAGAGTTTAGCCATCCCGACAGCTCAATTAATGTTGTGCTAAAACTGAAA
AATAAATTCGCCGTACTGAGCGTCAGTAACCAAGGGCCGGCACTACCAGAGAACATGGCTGAGCAGATTTTTGAGTCCAT
GGTATCTGTGCGAGCGCAAAAAGCCCAAGATAAGCCGCACCTAGGCTTGGGTCTTTATATCGCTAGACTTATTTGCCAAT
TTCATGACGGTAAAATTAGCGCCTGTAATACCCAAGATAAGGCCGGAAATGTTAGCGGCGTTAAGATCACGATTAAACTA
CCAATAAGCAAAGAAGGTCTTTAA

Upstream 100 bases:

>100_bases
TAGTTTATAAACAGGCTCATTAGTTAACTCATGGATAGGGTTATAGTCGAGTCATCTTCAGGTCATAATTAATGGCCATC
ATTTAGGTAGTTGTTACGCC

Downstream 100 bases:

>100_bases
AAGTGTTAGGCCTGTTTCAAACAATGGCAAAATTGAAAACTGCTCCTGAAAGCGAATGTTGAAGATAATGACACTTTATT
TTGGCCGTTTAGATGTTAAG

Product: histidine kinase

Products: NA

Alternate protein names: Histidine kinase sensory protein ExoS [H]

Number of amino acids: Translated: 727; Mature: 727

Protein sequence:

>727_residues
MFNLPIGLRTKVAVLSLFLLCLPWLGYQYVWEMEKYLRHGQEKTLEGTTQALATALHERPKLFDSQASFLTQVEKGRDLY
AYPLSGPIQLDGKLADWSSYRHRALNYGDDYQIYKRNENQPLNLSFTHMVGKYAGYLYAFFEVSDPHVVYRGKNSLSIDN
NDHIAIATLAPDGKFRRYIVATTQDGWISAFELPEDPSLSTPVTPEVKIQGKWTKSKQGYNVELRIPLNMVGSKLGFAVY
DVNDKKSRVLDAVVGTSAIDDVSKLGTVLVPSPEIESIIKGMSHNSSRIWVVDKHGRVLAKSGDIRSDNSVWSRANVDND
DNSGWEQFKHKYLHPLYYKILTTPAKDFIDSLQDSTVLQGSHISKALNGEQGSTWRLTPDNKAVVLAAASPIWIDDKVMG
VVIAEETTHGIRTLRNKALEKLFNVILTIMSMGTLALFFFASNISSRIRKLRDEAEQAIDSQGRIKNEIQGSKVRDEIGD
LSRSFASIVSRLSQYTHYLENMSSRLSHELRTPVAVVRSSLEHLGLQQLSPDSRKYVDRAQEGVNRLNMILNNMSEATRL
EASLSHADTTVFPLEKVINGCMQGYQMTYPNQAFELDITQESIAVLGVPEYIAQLMDKLIANAQEFSHPDSSINVVLKLK
NKFAVLSVSNQGPALPENMAEQIFESMVSVRAQKAQDKPHLGLGLYIARLICQFHDGKISACNTQDKAGNVSGVKITIKL
PISKEGL

Sequences:

>Translated_727_residues
MFNLPIGLRTKVAVLSLFLLCLPWLGYQYVWEMEKYLRHGQEKTLEGTTQALATALHERPKLFDSQASFLTQVEKGRDLY
AYPLSGPIQLDGKLADWSSYRHRALNYGDDYQIYKRNENQPLNLSFTHMVGKYAGYLYAFFEVSDPHVVYRGKNSLSIDN
NDHIAIATLAPDGKFRRYIVATTQDGWISAFELPEDPSLSTPVTPEVKIQGKWTKSKQGYNVELRIPLNMVGSKLGFAVY
DVNDKKSRVLDAVVGTSAIDDVSKLGTVLVPSPEIESIIKGMSHNSSRIWVVDKHGRVLAKSGDIRSDNSVWSRANVDND
DNSGWEQFKHKYLHPLYYKILTTPAKDFIDSLQDSTVLQGSHISKALNGEQGSTWRLTPDNKAVVLAAASPIWIDDKVMG
VVIAEETTHGIRTLRNKALEKLFNVILTIMSMGTLALFFFASNISSRIRKLRDEAEQAIDSQGRIKNEIQGSKVRDEIGD
LSRSFASIVSRLSQYTHYLENMSSRLSHELRTPVAVVRSSLEHLGLQQLSPDSRKYVDRAQEGVNRLNMILNNMSEATRL
EASLSHADTTVFPLEKVINGCMQGYQMTYPNQAFELDITQESIAVLGVPEYIAQLMDKLIANAQEFSHPDSSINVVLKLK
NKFAVLSVSNQGPALPENMAEQIFESMVSVRAQKAQDKPHLGLGLYIARLICQFHDGKISACNTQDKAGNVSGVKITIKL
PISKEGL
>Mature_727_residues
MFNLPIGLRTKVAVLSLFLLCLPWLGYQYVWEMEKYLRHGQEKTLEGTTQALATALHERPKLFDSQASFLTQVEKGRDLY
AYPLSGPIQLDGKLADWSSYRHRALNYGDDYQIYKRNENQPLNLSFTHMVGKYAGYLYAFFEVSDPHVVYRGKNSLSIDN
NDHIAIATLAPDGKFRRYIVATTQDGWISAFELPEDPSLSTPVTPEVKIQGKWTKSKQGYNVELRIPLNMVGSKLGFAVY
DVNDKKSRVLDAVVGTSAIDDVSKLGTVLVPSPEIESIIKGMSHNSSRIWVVDKHGRVLAKSGDIRSDNSVWSRANVDND
DNSGWEQFKHKYLHPLYYKILTTPAKDFIDSLQDSTVLQGSHISKALNGEQGSTWRLTPDNKAVVLAAASPIWIDDKVMG
VVIAEETTHGIRTLRNKALEKLFNVILTIMSMGTLALFFFASNISSRIRKLRDEAEQAIDSQGRIKNEIQGSKVRDEIGD
LSRSFASIVSRLSQYTHYLENMSSRLSHELRTPVAVVRSSLEHLGLQQLSPDSRKYVDRAQEGVNRLNMILNNMSEATRL
EASLSHADTTVFPLEKVINGCMQGYQMTYPNQAFELDITQESIAVLGVPEYIAQLMDKLIANAQEFSHPDSSINVVLKLK
NKFAVLSVSNQGPALPENMAEQIFESMVSVRAQKAQDKPHLGLGLYIARLICQFHDGKISACNTQDKAGNVSGVKITIKL
PISKEGL

Specific function: Member of a two-component regulatory system ChvG(ExoS)/ChvI involved in regulating the production of succinoglycan. Activates ChvI by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=256, Percent_Identity=24.609375, Blast_Score=94, Evalue=4e-20,
Organism=Escherichia coli, GI1786912, Length=238, Percent_Identity=24.7899159663866, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790346, Length=285, Percent_Identity=23.5087719298246, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 81290; Mature: 81290

Theoretical pI: Translated: 8.04; Mature: 8.04

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNLPIGLRTKVAVLSLFLLCLPWLGYQYVWEMEKYLRHGQEKTLEGTTQALATALHERP
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
KLFDSQASFLTQVEKGRDLYAYPLSGPIQLDGKLADWSSYRHRALNYGDDYQIYKRNENQ
HHHHHHHHHHHHHHCCCCEEEECCCCCEEECCEECCHHHHHHHHCCCCCCEEEEECCCCC
PLNLSFTHMVGKYAGYLYAFFEVSDPHVVYRGKNSLSIDNNDHIAIATLAPDGKFRRYIV
CCCEEHHHHHHHHHCEEEEEEEECCCEEEEECCCCEEECCCCCEEEEEECCCCCEEEEEE
ATTQDGWISAFELPEDPSLSTPVTPEVKIQGKWTKSKQGYNVELRIPLNMVGSKLGFAVY
EECCCCCEEEECCCCCCCCCCCCCCCEEEEEEEECCCCCCEEEEEECHHHHCHHHCEEEE
DVNDKKSRVLDAVVGTSAIDDVSKLGTVLVPSPEIESIIKGMSHNSSRIWVVDKHGRVLA
ECCCHHHHHHHHHHCCHHHHHHHHCCEEECCCCCHHHHHHCCCCCCCEEEEEECCCEEEE
KSGDIRSDNSVWSRANVDNDDNSGWEQFKHKYLHPLYYKILTTPAKDFIDSLQDSTVLQG
ECCCCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEECC
SHISKALNGEQGSTWRLTPDNKAVVLAAASPIWIDDKVMGVVIAEETTHGIRTLRNKALE
HHHHHHHCCCCCCEEEECCCCCEEEEEECCCEEECCCEEEEEEECCCHHHHHHHHHHHHH
KLFNVILTIMSMGTLALFFFASNISSRIRKLRDEAEQAIDSQGRIKNEIQGSKVRDEIGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHH
LSRSFASIVSRLSQYTHYLENMSSRLSHELRTPVAVVRSSLEHLGLQQLSPDSRKYVDRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHCCCCHHHHHHHH
QEGVNRLNMILNNMSEATRLEASLSHADTTVFPLEKVINGCMQGYQMTYPNQAFELDITQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEECCCCCEEEEEECH
ESIAVLGVPEYIAQLMDKLIANAQEFSHPDSSINVVLKLKNKFAVLSVSNQGPALPENMA
HHHEEEECHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCEEEEEECCCCCCCCHHHH
EQIFESMVSVRAQKAQDKPHLGLGLYIARLICQFHDGKISACNTQDKAGNVSGVKITIKL
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCEEEEEEEE
PISKEGL
CCCCCCC
>Mature Secondary Structure
MFNLPIGLRTKVAVLSLFLLCLPWLGYQYVWEMEKYLRHGQEKTLEGTTQALATALHERP
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
KLFDSQASFLTQVEKGRDLYAYPLSGPIQLDGKLADWSSYRHRALNYGDDYQIYKRNENQ
HHHHHHHHHHHHHHCCCCEEEECCCCCEEECCEECCHHHHHHHHCCCCCCEEEEECCCCC
PLNLSFTHMVGKYAGYLYAFFEVSDPHVVYRGKNSLSIDNNDHIAIATLAPDGKFRRYIV
CCCEEHHHHHHHHHCEEEEEEEECCCEEEEECCCCEEECCCCCEEEEEECCCCCEEEEEE
ATTQDGWISAFELPEDPSLSTPVTPEVKIQGKWTKSKQGYNVELRIPLNMVGSKLGFAVY
EECCCCCEEEECCCCCCCCCCCCCCCEEEEEEEECCCCCCEEEEEECHHHHCHHHCEEEE
DVNDKKSRVLDAVVGTSAIDDVSKLGTVLVPSPEIESIIKGMSHNSSRIWVVDKHGRVLA
ECCCHHHHHHHHHHCCHHHHHHHHCCEEECCCCCHHHHHHCCCCCCCEEEEEECCCEEEE
KSGDIRSDNSVWSRANVDNDDNSGWEQFKHKYLHPLYYKILTTPAKDFIDSLQDSTVLQG
ECCCCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEECC
SHISKALNGEQGSTWRLTPDNKAVVLAAASPIWIDDKVMGVVIAEETTHGIRTLRNKALE
HHHHHHHCCCCCCEEEECCCCCEEEEEECCCEEECCCEEEEEEECCCHHHHHHHHHHHHH
KLFNVILTIMSMGTLALFFFASNISSRIRKLRDEAEQAIDSQGRIKNEIQGSKVRDEIGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHH
LSRSFASIVSRLSQYTHYLENMSSRLSHELRTPVAVVRSSLEHLGLQQLSPDSRKYVDRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHCCCCHHHHHHHH
QEGVNRLNMILNNMSEATRLEASLSHADTTVFPLEKVINGCMQGYQMTYPNQAFELDITQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEECCCCCEEEEEECH
ESIAVLGVPEYIAQLMDKLIANAQEFSHPDSSINVVLKLKNKFAVLSVSNQGPALPENMA
HHHEEEECHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCEEEEEECCCCCCCCHHHH
EQIFESMVSVRAQKAQDKPHLGLGLYIARLICQFHDGKISACNTQDKAGNVSGVKITIKL
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCEEEEEEEE
PISKEGL
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9422587; 11481430; 7559334 [H]