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The map label for this gene is dxs [H]

Identifier: 167623331

GI number: 167623331

Start: 1691027

End: 1692805

Strand: Direct

Name: dxs [H]

Synonym: Shal_1400

Alternate gene names: 167623331

Gene position: 1691027-1692805 (Clockwise)

Preceding gene: 167623330

Following gene: 167623332

Centisome position: 32.35

GC content: 47.72

Gene sequence:

>1779_bases
ATGAAAACCCATCAATTAATTGTGCCGACTCTCAATGAACTGAAACAGCAGTCGGCGGCGCAATTAACCCAATTAGCCGA
AGATATTAGGCAGTTTCTTATTAGCAATATTTCTGCGACTGGTGGACACATCGGCGCTAACTTATCAGTGGTAGAACTCA
CGGTTGCCATTCATGCACTCTTTGACTCTCCAGCTGATAAAGTGATTTTTGATACGGGTCATCAAGGTTATACCCATAAG
ATTTTAACGGGTCGCGTGGAAAATTTTGCCACATTAAACCAATATCGCGGCATGAACCGATTCGTTGCCAGAGATGAAAG
TGAGCATGACGCAATCGATGCGTCACATGCAGGTACTTCACTCTCTATTGCGTCAGGCTATGCCAAAGCCCTTAAGCTGA
CTTCGCCGGCTAACTATGTTGTTTCTTTGATCGGTGACGGCTCGATGGTTGAGGGCATGGCCTTCGAAGGGCTTAATTAC
TGTGCTGAAGATAAAGACAGTAAGCTTGTGATTGTGCTTAACGATAATGAAATGGCGATTGCGAAGTCTGTTGGAGGAAT
GCGCAATCTTACAGCAGGGGAAAACTGGCAGAGCAATAGCCGAGCCTTCTTCGAAGGGATGGGCTTTGCCTATCTGCTGG
TCGAAGATGGCCATGATATGCCGGCTCTGCTTGAGCAATTAGCTGCAGCGAAGCAGTTAGCGCGGCCAGTGATTGTTCAT
GTTAAAACCGAGAAAGGTAAAGGCTTAGCCTGTGCGAAAGATCATCCCTATAAAATGCACTTCTCCATGCCATTCGATGC
TGCTACTGGTAAAGGTGCAGCTGCAACGGTTGTGGGGCGCACCTACGCGGTTGTTGCGGCTGAAGCACTGAAGCAAAAGA
TGACAACGGATGACGATGTATTTGCCATGACCCCAGCTACCCCTTATGCATCATCATTGGATGAGTGCTTAGCACTGTTT
CCTGAGCGTGCACTGGATGTGGGAATGGCTGAGCAACAAGCGGTAGGTATGGCTTGTGGTCTAGCACTGGGTGGTAAGAA
GCCTGTCGTCTGTATGCAAACGACCTTCATGCAGCGTGCCTACGATCAGCTTATTCATGATGCTTGTTATATGGATTTAC
CTGTGACGGTATTTGGCGTTCGTGCTGGCTTTGCTGGATATGATGGCGCGACCCACCACGGAATTTATGATATTCCCTAT
CTGCGCTCATTCCCAAATATGCAGTTGGTGTACCCAGCAAGCTCTGCAGCATTAACAGAACTGATTGAGAAGCGACTCGA
CAATCCTCAGGGACCTATGGTGATCCTCTATCCCTATGAGCCAATTCCAACTCCAGAGCCCGATACTGGTTTGATTGAGC
CTTGTGGCTTATCTGTCCCAGTGCAGGGCCGTGATGGCTATTTAGTCTGTTTGGGTAACCGTTTAGTTGCGGCATATGAG
CTTAAAGCACTATTGGAAGCGCAAGGCAAAGACTACGGCATCATCTGTGTGCAATCGATTAAACCTTTCCCTGCTGAGCG
TTTCGTTGAGTTAGTTGCACCAACAAAGCACCTGATAACACTTGAAGAAAGCGTGCTTAATGGCGGTTTTGGCTCTCTAG
TGCTAGAAACCCTTGCTGATGCAAACTTATCTATGCAGGTACTAAGAAGCGGCGTTGATGACAAGTTTGTTTATCCAGGC
AGTAAAGATGAGTGCAGCGCCGAGTGCGGCATGATGCCAGGGCAGATCATTGAGCAAATTGCACAGCAATGGCCAAACTA
TTTAGGAGTGAACAAGTGA

Upstream 100 bases:

>100_bases
AAGTGATCGGTATCAAAGCGGGCATTATTTATGACGAAACAGACCCTTATGGCACCAATACTGTGCTTATCTGCGTAAAG
CCTAATAGTAAGGATTGATA

Downstream 100 bases:

>100_bases
TGCGTTTAGCCGGTAAAGTCGCAGTTATTACTGGATCTTCAAGAGGCATTGGCGCCGCGATCGCACAGGAGTATTGCGCT
CAAGGAGCCAAGGTGGTGAT

Product: transketolase central region

Products: NA

Alternate protein names: 1-deoxyxylulose-5-phosphate synthase; DXP synthase; DXPS [H]

Number of amino acids: Translated: 592; Mature: 592

Protein sequence:

>592_residues
MKTHQLIVPTLNELKQQSAAQLTQLAEDIRQFLISNISATGGHIGANLSVVELTVAIHALFDSPADKVIFDTGHQGYTHK
ILTGRVENFATLNQYRGMNRFVARDESEHDAIDASHAGTSLSIASGYAKALKLTSPANYVVSLIGDGSMVEGMAFEGLNY
CAEDKDSKLVIVLNDNEMAIAKSVGGMRNLTAGENWQSNSRAFFEGMGFAYLLVEDGHDMPALLEQLAAAKQLARPVIVH
VKTEKGKGLACAKDHPYKMHFSMPFDAATGKGAAATVVGRTYAVVAAEALKQKMTTDDDVFAMTPATPYASSLDECLALF
PERALDVGMAEQQAVGMACGLALGGKKPVVCMQTTFMQRAYDQLIHDACYMDLPVTVFGVRAGFAGYDGATHHGIYDIPY
LRSFPNMQLVYPASSAALTELIEKRLDNPQGPMVILYPYEPIPTPEPDTGLIEPCGLSVPVQGRDGYLVCLGNRLVAAYE
LKALLEAQGKDYGIICVQSIKPFPAERFVELVAPTKHLITLEESVLNGGFGSLVLETLADANLSMQVLRSGVDDKFVYPG
SKDECSAECGMMPGQIIEQIAQQWPNYLGVNK

Sequences:

>Translated_592_residues
MKTHQLIVPTLNELKQQSAAQLTQLAEDIRQFLISNISATGGHIGANLSVVELTVAIHALFDSPADKVIFDTGHQGYTHK
ILTGRVENFATLNQYRGMNRFVARDESEHDAIDASHAGTSLSIASGYAKALKLTSPANYVVSLIGDGSMVEGMAFEGLNY
CAEDKDSKLVIVLNDNEMAIAKSVGGMRNLTAGENWQSNSRAFFEGMGFAYLLVEDGHDMPALLEQLAAAKQLARPVIVH
VKTEKGKGLACAKDHPYKMHFSMPFDAATGKGAAATVVGRTYAVVAAEALKQKMTTDDDVFAMTPATPYASSLDECLALF
PERALDVGMAEQQAVGMACGLALGGKKPVVCMQTTFMQRAYDQLIHDACYMDLPVTVFGVRAGFAGYDGATHHGIYDIPY
LRSFPNMQLVYPASSAALTELIEKRLDNPQGPMVILYPYEPIPTPEPDTGLIEPCGLSVPVQGRDGYLVCLGNRLVAAYE
LKALLEAQGKDYGIICVQSIKPFPAERFVELVAPTKHLITLEESVLNGGFGSLVLETLADANLSMQVLRSGVDDKFVYPG
SKDECSAECGMMPGQIIEQIAQQWPNYLGVNK
>Mature_592_residues
MKTHQLIVPTLNELKQQSAAQLTQLAEDIRQFLISNISATGGHIGANLSVVELTVAIHALFDSPADKVIFDTGHQGYTHK
ILTGRVENFATLNQYRGMNRFVARDESEHDAIDASHAGTSLSIASGYAKALKLTSPANYVVSLIGDGSMVEGMAFEGLNY
CAEDKDSKLVIVLNDNEMAIAKSVGGMRNLTAGENWQSNSRAFFEGMGFAYLLVEDGHDMPALLEQLAAAKQLARPVIVH
VKTEKGKGLACAKDHPYKMHFSMPFDAATGKGAAATVVGRTYAVVAAEALKQKMTTDDDVFAMTPATPYASSLDECLALF
PERALDVGMAEQQAVGMACGLALGGKKPVVCMQTTFMQRAYDQLIHDACYMDLPVTVFGVRAGFAGYDGATHHGIYDIPY
LRSFPNMQLVYPASSAALTELIEKRLDNPQGPMVILYPYEPIPTPEPDTGLIEPCGLSVPVQGRDGYLVCLGNRLVAAYE
LKALLEAQGKDYGIICVQSIKPFPAERFVELVAPTKHLITLEESVLNGGFGSLVLETLADANLSMQVLRSGVDDKFVYPG
SKDECSAECGMMPGQIIEQIAQQWPNYLGVNK

Specific function: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) [H]

COG id: COG1154

COG function: function code HI; Deoxyxylulose-5-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family. DXPS subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786622, Length=600, Percent_Identity=32.5, Blast_Score=318, Evalue=9e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005477
- InterPro:   IPR011766
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02775 TPP_enzyme_C; PF02779 Transket_pyr; PF02780 Transketolase_C [H]

EC number: =2.2.1.7 [H]

Molecular weight: Translated: 63947; Mature: 63947

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS00801 TRANSKETOLASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTHQLIVPTLNELKQQSAAQLTQLAEDIRQFLISNISATGGHIGANLSVVELTVAIHAL
CCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHH
FDSPADKVIFDTGHQGYTHKILTGRVENFATLNQYRGMNRFVARDESEHDAIDASHAGTS
HCCCCCCEEEECCCCCCEEHHHHCCHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCE
LSIASGYAKALKLTSPANYVVSLIGDGSMVEGMAFEGLNYCAEDKDSKLVIVLNDNEMAI
EEEHHHHHHHEEECCCHHEEEEEECCCCCCCCHHHCCCCCCCCCCCCEEEEEECCCCEEE
AKSVGGMRNLTAGENWQSNSRAFFEGMGFAYLLVEDGHDMPALLEQLAAAKQLARPVIVH
HHHCCCCCCCCCCCCCCCCCCHHEECCCEEEEEEECCCCHHHHHHHHHHHHHHCCCEEEE
VKTEKGKGLACAKDHPYKMHFSMPFDAATGKGAAATVVGRTYAVVAAEALKQKMTTDDDV
EEECCCCCEEEECCCCEEEEEECCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCE
FAMTPATPYASSLDECLALFPERALDVGMAEQQAVGMACGLALGGKKPVVCMQTTFMQRA
EEECCCCCCHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHEECCCCCCEEEHHHHHHHHH
YDQLIHDACYMDLPVTVFGVRAGFAGYDGATHHGIYDIPYLRSFPNMQLVYPASSAALTE
HHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCEECCHHHHCCCCCEEEECCCHHHHHH
LIEKRLDNPQGPMVILYPYEPIPTPEPDTGLIEPCGLSVPVQGRDGYLVCLGNRLVAAYE
HHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEECCCEEHHHH
LKALLEAQGKDYGIICVQSIKPFPAERFVELVAPTKHLITLEESVLNGGFGSLVLETLAD
HHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHCCCHHEEEEHHHHHCCCHHHHHHHHHHC
ANLSMQVLRSGVDDKFVYPGSKDECSAECGMMPGQIIEQIAQQWPNYLGVNK
CCCCHHHHHCCCCCCEECCCCCCCCCHHCCCCCHHHHHHHHHHCCHHCCCCC
>Mature Secondary Structure
MKTHQLIVPTLNELKQQSAAQLTQLAEDIRQFLISNISATGGHIGANLSVVELTVAIHAL
CCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHH
FDSPADKVIFDTGHQGYTHKILTGRVENFATLNQYRGMNRFVARDESEHDAIDASHAGTS
HCCCCCCEEEECCCCCCEEHHHHCCHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCE
LSIASGYAKALKLTSPANYVVSLIGDGSMVEGMAFEGLNYCAEDKDSKLVIVLNDNEMAI
EEEHHHHHHHEEECCCHHEEEEEECCCCCCCCHHHCCCCCCCCCCCCEEEEEECCCCEEE
AKSVGGMRNLTAGENWQSNSRAFFEGMGFAYLLVEDGHDMPALLEQLAAAKQLARPVIVH
HHHCCCCCCCCCCCCCCCCCCHHEECCCEEEEEEECCCCHHHHHHHHHHHHHHCCCEEEE
VKTEKGKGLACAKDHPYKMHFSMPFDAATGKGAAATVVGRTYAVVAAEALKQKMTTDDDV
EEECCCCCEEEECCCCEEEEEECCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCE
FAMTPATPYASSLDECLALFPERALDVGMAEQQAVGMACGLALGGKKPVVCMQTTFMQRA
EEECCCCCCHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHEECCCCCCEEEHHHHHHHHH
YDQLIHDACYMDLPVTVFGVRAGFAGYDGATHHGIYDIPYLRSFPNMQLVYPASSAALTE
HHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCEECCHHHHCCCCCEEEECCCHHHHHH
LIEKRLDNPQGPMVILYPYEPIPTPEPDTGLIEPCGLSVPVQGRDGYLVCLGNRLVAAYE
HHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEECCCEEHHHH
LKALLEAQGKDYGIICVQSIKPFPAERFVELVAPTKHLITLEESVLNGGFGSLVLETLAD
HHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHCCCHHEEEEHHHHHCCCHHHHHHHHHHC
ANLSMQVLRSGVDDKFVYPGSKDECSAECGMMPGQIIEQIAQQWPNYLGVNK
CCCCHHHHHCCCCCCEECCCCCCCCCHHCCCCCHHHHHHHHHHCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]