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The map label for this gene is xanQ [H]

Identifier: 167623305

GI number: 167623305

Start: 1649627

End: 1651075

Strand: Direct

Name: xanQ [H]

Synonym: Shal_1373

Alternate gene names: 167623305

Gene position: 1649627-1651075 (Clockwise)

Preceding gene: 167623304

Following gene: 167623308

Centisome position: 31.56

GC content: 45.27

Gene sequence:

>1449_bases
ATGGACAATACCCAATCTACCAGTATCGAGTTAGCCTACGGCCTTGATAGCAAACCGCCCTTCTTATCATCACTATTTGC
CGCTATGCAGCATTTGCTCGCCATGATTGTTGGTGTGGCGACACCGCCAATTCTAATTGGTAGTGCACTCAATCTAAGTC
CTGAGAATGTCACCTACTTAGTGAGTATGTCACTATTTATGTCAGGCATTGGTACCTTTGTGCAGGTAAAGCGTCTTGGT
GGGTTTATTGGCTCAGGTCTACTGACAGTTCAGGCCACAAGCTTTGCCTATCCTGCAACAATTATCTCAATCGGCACCTC
ATTTTTGGCTGCGGGTATGAGCCAAGATCAGATGTTGAGCACCATCTTTGGGGTGCTATTTGCAGGCTCATTTGTCACTA
TATTTGCCAGCCGCTTATTGCCAATGCTACGTAAAGTCATATCGCCGACAGTCTCTGGCATCACAGTGATGTTGATAGGC
ATATCTTTAGTTGAAGTCGGGATGACAGACTTTGCTGGCGGCTATGCCAGTAAACTTGACGGCTCATTCGGCTCTATAGA
AAATCTGATGCTAGGCTTTATAGTACTTGTCAGTATTTTACTTTTCTTCCGTAGCCGCAGTCAGTATGTCAGGATGAGCG
CCATCATCTTGGGTATGGCCCTTGGCTATTTAGTCGCGCTCTATATGGGAAAAACCGATTTTAGCGCTTTTTCCAATGTA
CCTCTGTATAACATACCAGCCCCCTTCAAGTTCGGTCTGTTTCAAATAGATTGGCAAGCTTTCTTTCTTATTGGTTTTGT
CTATCTAGTCGTGATTATTGAAGCCGTTGGTGCGTTAACTGCGACTTGTATGCTTTGTAACAGACCCCTAATGGGCAAAG
AATACAATCAAAGGATCTCCGGAGGGGTACTTGCAGATGGCGTGGTCTCCGCTATCGCATCGGTTTTTAACGCATTTCCT
CTGACTGCATTTAGCCAGAACAATGGCGTGATTCAGATGACTGGCGTGGCCAGTCGTAAGGTTGGACTATTTGTTGCAAC
GCTGCTGATTATCTTCGGCCTATTTCCGGTGATTTCTATCATTTTTACCTCATTGCCTAAGCCTATTTTAGGCGGGGCGA
CATTAATCCTATTTGGTACAGTGGCCGCTGCAGGAATAGGAATTATCACCCAAGTTAAACTTGATCGCCGTGAAAGTATG
ATTATTTCGGTCTCTATTGGGGTCGCATTAGGCGCAGCGTTTGTACCTGATGCAATTTCTCTGCTTCCGCCTATGCTGCA
AAAAATGCTTGGAACACCAGCGATTGCTGGAGGTTTGACTGCGCTAATGGTTAACCTACTTCTGCCGCGTCCAGTTCCTG
AGACAATACGTAAAGCCGAATCTGTGCGTAAGGTGAAAGCAAAATTTGATGCTTCATCCCAAGATAAAAAAAAATCAGCT
ACAGAGTAG

Upstream 100 bases:

>100_bases
TTTAGTGCTAATACTAAATCAGCATCACATTACTTGTTTTTCCTACCTTAATTTTTATATGTGACTCTGCCTAGAGTCAG
CCAGATATTTAAGGTCAATT

Downstream 100 bases:

>100_bases
TTAAGTTCTTGTGTAGCGCCGATTAACTGTGACACCCATAATCGTTGGCTGGATTTTTAATTCTAGTAAATGAAATAATT
ATGGGTGGCCTTCATGGTTA

Product: uracil-xanthine permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 482; Mature: 482

Protein sequence:

>482_residues
MDNTQSTSIELAYGLDSKPPFLSSLFAAMQHLLAMIVGVATPPILIGSALNLSPENVTYLVSMSLFMSGIGTFVQVKRLG
GFIGSGLLTVQATSFAYPATIISIGTSFLAAGMSQDQMLSTIFGVLFAGSFVTIFASRLLPMLRKVISPTVSGITVMLIG
ISLVEVGMTDFAGGYASKLDGSFGSIENLMLGFIVLVSILLFFRSRSQYVRMSAIILGMALGYLVALYMGKTDFSAFSNV
PLYNIPAPFKFGLFQIDWQAFFLIGFVYLVVIIEAVGALTATCMLCNRPLMGKEYNQRISGGVLADGVVSAIASVFNAFP
LTAFSQNNGVIQMTGVASRKVGLFVATLLIIFGLFPVISIIFTSLPKPILGGATLILFGTVAAAGIGIITQVKLDRRESM
IISVSIGVALGAAFVPDAISLLPPMLQKMLGTPAIAGGLTALMVNLLLPRPVPETIRKAESVRKVKAKFDASSQDKKKSA
TE

Sequences:

>Translated_482_residues
MDNTQSTSIELAYGLDSKPPFLSSLFAAMQHLLAMIVGVATPPILIGSALNLSPENVTYLVSMSLFMSGIGTFVQVKRLG
GFIGSGLLTVQATSFAYPATIISIGTSFLAAGMSQDQMLSTIFGVLFAGSFVTIFASRLLPMLRKVISPTVSGITVMLIG
ISLVEVGMTDFAGGYASKLDGSFGSIENLMLGFIVLVSILLFFRSRSQYVRMSAIILGMALGYLVALYMGKTDFSAFSNV
PLYNIPAPFKFGLFQIDWQAFFLIGFVYLVVIIEAVGALTATCMLCNRPLMGKEYNQRISGGVLADGVVSAIASVFNAFP
LTAFSQNNGVIQMTGVASRKVGLFVATLLIIFGLFPVISIIFTSLPKPILGGATLILFGTVAAAGIGIITQVKLDRRESM
IISVSIGVALGAAFVPDAISLLPPMLQKMLGTPAIAGGLTALMVNLLLPRPVPETIRKAESVRKVKAKFDASSQDKKKSA
TE
>Mature_482_residues
MDNTQSTSIELAYGLDSKPPFLSSLFAAMQHLLAMIVGVATPPILIGSALNLSPENVTYLVSMSLFMSGIGTFVQVKRLG
GFIGSGLLTVQATSFAYPATIISIGTSFLAAGMSQDQMLSTIFGVLFAGSFVTIFASRLLPMLRKVISPTVSGITVMLIG
ISLVEVGMTDFAGGYASKLDGSFGSIENLMLGFIVLVSILLFFRSRSQYVRMSAIILGMALGYLVALYMGKTDFSAFSNV
PLYNIPAPFKFGLFQIDWQAFFLIGFVYLVVIIEAVGALTATCMLCNRPLMGKEYNQRISGGVLADGVVSAIASVFNAFP
LTAFSQNNGVIQMTGVASRKVGLFVATLLIIFGLFPVISIIFTSLPKPILGGATLILFGTVAAAGIGIITQVKLDRRESM
IISVSIGVALGAAFVPDAISLLPPMLQKMLGTPAIAGGLTALMVNLLLPRPVPETIRKAESVRKVKAKFDASSQDKKKSA
TE

Specific function: Specific, proton motive force-dependent high-affinity transporter for xanthine [H]

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680148, Length=518, Percent_Identity=25.0965250965251, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI40316845, Length=518, Percent_Identity=25.0965250965251, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI44680145, Length=448, Percent_Identity=24.7767857142857, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI44680143, Length=453, Percent_Identity=24.5033112582781, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI87082178, Length=449, Percent_Identity=45.43429844098, Blast_Score=400, Evalue=1e-113,
Organism=Escherichia coli, GI1790087, Length=449, Percent_Identity=42.3162583518931, Blast_Score=351, Evalue=5e-98,
Organism=Escherichia coli, GI87082181, Length=445, Percent_Identity=31.0112359550562, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI87081818, Length=467, Percent_Identity=24.6252676659529, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1788843, Length=395, Percent_Identity=26.0759493670886, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017588
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 51050; Mature: 51050

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNTQSTSIELAYGLDSKPPFLSSLFAAMQHLLAMIVGVATPPILIGSALNLSPENVTYL
CCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCHHHH
VSMSLFMSGIGTFVQVKRLGGFIGSGLLTVQATSFAYPATIISIGTSFLAAGMSQDQMLS
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHH
TIFGVLFAGSFVTIFASRLLPMLRKVISPTVSGITVMLIGISLVEVGMTDFAGGYASKLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHCCCHHHHCC
GSFGSIENLMLGFIVLVSILLFFRSRSQYVRMSAIILGMALGYLVALYMGKTDFSAFSNV
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCC
PLYNIPAPFKFGLFQIDWQAFFLIGFVYLVVIIEAVGALTATCMLCNRPLMGKEYNQRIS
CCEECCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHC
GGVLADGVVSAIASVFNAFPLTAFSQNNGVIQMTGVASRKVGLFVATLLIIFGLFPVISI
CCHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
IFTSLPKPILGGATLILFGTVAAAGIGIITQVKLDRRESMIISVSIGVALGAAFVPDAIS
HHHHCCCCHHCCHHHHHHHHHHHHHHHHHEEEEECCCCCEEEEEEHHHHHHHHHHHHHHH
LLPPMLQKMLGTPAIAGGLTALMVNLLLPRPVPETIRKAESVRKVKAKFDASSQDKKKSA
HHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC
TE
CC
>Mature Secondary Structure
MDNTQSTSIELAYGLDSKPPFLSSLFAAMQHLLAMIVGVATPPILIGSALNLSPENVTYL
CCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCHHHH
VSMSLFMSGIGTFVQVKRLGGFIGSGLLTVQATSFAYPATIISIGTSFLAAGMSQDQMLS
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHH
TIFGVLFAGSFVTIFASRLLPMLRKVISPTVSGITVMLIGISLVEVGMTDFAGGYASKLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHCCCHHHHCC
GSFGSIENLMLGFIVLVSILLFFRSRSQYVRMSAIILGMALGYLVALYMGKTDFSAFSNV
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCC
PLYNIPAPFKFGLFQIDWQAFFLIGFVYLVVIIEAVGALTATCMLCNRPLMGKEYNQRIS
CCEECCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHC
GGVLADGVVSAIASVFNAFPLTAFSQNNGVIQMTGVASRKVGLFVATLLIIFGLFPVISI
CCHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
IFTSLPKPILGGATLILFGTVAAAGIGIITQVKLDRRESMIISVSIGVALGAAFVPDAIS
HHHHCCCCHHCCHHHHHHHHHHHHHHHHHEEEEECCCCCEEEEEEHHHHHHHHHHHHHHH
LLPPMLQKMLGTPAIAGGLTALMVNLLLPRPVPETIRKAESVRKVKAKFDASSQDKKKSA
HHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC
TE
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]