Click here to switch to the map view.

The map label for this gene is fadE [H]

Identifier: 167623200

GI number: 167623200

Start: 1543220

End: 1545457

Strand: Reverse

Name: fadE [H]

Synonym: Shal_1266

Alternate gene names: 167623200

Gene position: 1545457-1543220 (Counterclockwise)

Preceding gene: 167623201

Following gene: 167623194

Centisome position: 29.57

GC content: 47.32

Gene sequence:

>2238_bases
ATGAGCATAAGAACACAATTTAGAAAAATATTGCCAACCATATCAACCACAGAGCAAGAAGCACTCGATGCCGGAGATGT
GTGGTTAGAAGGTTCGATTTATCAAGGCGTTCCTGACTTTGCCGCCCTTCGCGAGATCCCAGTTGCAACACTATCAAACG
ATGAGCAAGCCTTCCTCGATGGCCCTGTTGCCACCTTACTTGATATGGTGGATGACTTTGAAATTCAGCAAAATAAGCAC
CTACCAGATAACATTCTTAACTTCTTAAAAGAGAACAAATTTTTCTCTCTTATTATCCCGAAATCTTTCGGTGGCCTCGA
GTTTAGCCCTTATGCTAACTCCACCATTGTGGCAACCATCGCCGCTAAAAGCTCCGCTGTTGCGGTAACGGTCATGGTAC
CTAACTCACTCGGCCCAGGTGAGCTACTGATGCACTACGGCACCTCTGAGCAGCAAGATTACTGGCTACCACGTCTGGCT
AACGGTCGTGAGATCCCCTGTTTTGCACTCACAAGCCCCGAGGCCGGTTCAGATGCAGGTAGCATTCCAGATATCGGTAT
CGTCACTATGGGTGAATACCAAGGTGAGCAGGTACTGGGTATGAATGTGACTTGGGATAAGCGTTACATCACGCTATCTT
CTATTGCGACAGTATTGGGCCTCGCATTTAAAGTCGAAGATCCGAACGGTCTACTCGGTGGCAAAGAAGACTTAGGGATC
ACCTGTGCGCTCATTCCAAGATCGCATCAAGGTGTTCAGCTAGGTAATCGTCATGATCCAATGGGCATTCGCTTCTACAA
CGGTACGACCCGTGGTGAAAATGTGTTTATCCCTATGGACTTCATTATTGGCGGACAGAAGAATATCGGTCGCGGCTGGT
CTATGCTCGTTGCCTGTCTGGGGGCTGGACGAGGGATCTCACTACCCGCCCTTGGTGCATCGGTCAGTCAGGCCTCTTTC
AAGTCTTCGGCTGAGTATGCCGCTGTACGAGAGCAGTTTGGTTTGTCGATTGGTAAGTTTGAAGGTATTCAAGAAAAACT
CGCCGATATCGCTGGTAAAACTTACCTACAAGAAGCGATGCGCGTACTGACCACAGAAGGCTTAGGTCTCGGTTTAAAGC
CATCGGTGGTTACCGCTATCGCTAAATACCATATGACCGAGCTTGGTCGTAACATCCTAGAATCGGCGATGGATATTCAA
GCAGGTAAGGCGATTCAGTGTGGTCCTCAAAATACCTTGGCCTCTGCTTATGTGGCGCAGCCCATTGCCATCACGGTTGA
AGGTGCAAATATTCTGACTCGTAACCTGATGATTTTTGGCCAAGGTGTGATGCGTTGTCACCCACACTTGCAGAGTATGG
TCGAGACCATCCACTCAAACGATAAGGGTGCCGATAAAAAGTTTAACAGTATCTTAAGTAAAACGATCGGCTACAGCGTG
GGTAATAGTTTACGTGGATTTAAGCTAGGGCTACTGCCTTTTACCGCCGCTGCCAGCTCTAATCTTGCAGAGGTTAAACC
TTACGAGCAATCGGTGAATAAGCTTGCCTCAAAGCTTGCAGTCTATGCTGATTTCTCACTATTAGTGCTTGGCGGTAAAC
TCAAGCAAGCAGAAATGCTTTCAGCGCGCCTAGGTGATGTGATGAGTTACCTGTATGCGGCAATGGCCTCTATCCGTTAC
TACGAAAAGAAACTTAGCGCAGAGCAGCGAAAAGAAGCGGCGCCTTACTTCCACTACGCCACGCGCTGGTCACTATGCCA
GGCAGAGAAAGCCCTGTTGGAGTTCTTAGATAACTTCCCATCATCGGCAACACGCAAGTTTATGCGTTTAATCACCGTCA
CTTACTCGGCTAAGATGCCAAAAGTCAATGATGATCTTGTTCGTGAGCTCGCTAAGCAAGCTCAGCTCAATACTGAGTTT
AAGAAGAACCTGACTCACCTTATTAAGCCTGTGGCTGGTGATGGTAACGATATCAACGAGCAAGCTTATCTTGCAAAAAT
GGCATGTTTACCACTACTTGCTAAGGTTAAGAAGGCCCTTAGGGCACGAACCTTTAAGGCTGGGGTTAAATTCTCGCTGA
CCTTAGATGCGGCGCTCGAAGCTAAGGTGATTACTGGCGATGAGCACAAGCAGCTACAAGATTATAATCTTAAACGTGAA
CGTGCGATTCGTGTCGATGAGTTTGATTTTGATATGAACTTAATTAGCGACAAGCCAGATTTAAAGATCGCTAACTAG

Upstream 100 bases:

>100_bases
AAATCCAAACAAGCGTTTAAATTTGTTGTTTGAAAGTTTGATCTACAGCTCATTTTGTGACGTAATGTGAACCATACTTC
TGGTCGGACGAGCATATAAT

Downstream 100 bases:

>100_bases
TCGTTAGCTAATCGATAGCAGTTTGATAGCTGCTCAGTAATCAGTTATAGACTGTCACTAAAAAGCCACCGCAAGGTGGT
TTTTTTAGCTTCGAAATAAG

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: ACDH [H]

Number of amino acids: Translated: 745; Mature: 744

Protein sequence:

>745_residues
MSIRTQFRKILPTISTTEQEALDAGDVWLEGSIYQGVPDFAALREIPVATLSNDEQAFLDGPVATLLDMVDDFEIQQNKH
LPDNILNFLKENKFFSLIIPKSFGGLEFSPYANSTIVATIAAKSSAVAVTVMVPNSLGPGELLMHYGTSEQQDYWLPRLA
NGREIPCFALTSPEAGSDAGSIPDIGIVTMGEYQGEQVLGMNVTWDKRYITLSSIATVLGLAFKVEDPNGLLGGKEDLGI
TCALIPRSHQGVQLGNRHDPMGIRFYNGTTRGENVFIPMDFIIGGQKNIGRGWSMLVACLGAGRGISLPALGASVSQASF
KSSAEYAAVREQFGLSIGKFEGIQEKLADIAGKTYLQEAMRVLTTEGLGLGLKPSVVTAIAKYHMTELGRNILESAMDIQ
AGKAIQCGPQNTLASAYVAQPIAITVEGANILTRNLMIFGQGVMRCHPHLQSMVETIHSNDKGADKKFNSILSKTIGYSV
GNSLRGFKLGLLPFTAAASSNLAEVKPYEQSVNKLASKLAVYADFSLLVLGGKLKQAEMLSARLGDVMSYLYAAMASIRY
YEKKLSAEQRKEAAPYFHYATRWSLCQAEKALLEFLDNFPSSATRKFMRLITVTYSAKMPKVNDDLVRELAKQAQLNTEF
KKNLTHLIKPVAGDGNDINEQAYLAKMACLPLLAKVKKALRARTFKAGVKFSLTLDAALEAKVITGDEHKQLQDYNLKRE
RAIRVDEFDFDMNLISDKPDLKIAN

Sequences:

>Translated_745_residues
MSIRTQFRKILPTISTTEQEALDAGDVWLEGSIYQGVPDFAALREIPVATLSNDEQAFLDGPVATLLDMVDDFEIQQNKH
LPDNILNFLKENKFFSLIIPKSFGGLEFSPYANSTIVATIAAKSSAVAVTVMVPNSLGPGELLMHYGTSEQQDYWLPRLA
NGREIPCFALTSPEAGSDAGSIPDIGIVTMGEYQGEQVLGMNVTWDKRYITLSSIATVLGLAFKVEDPNGLLGGKEDLGI
TCALIPRSHQGVQLGNRHDPMGIRFYNGTTRGENVFIPMDFIIGGQKNIGRGWSMLVACLGAGRGISLPALGASVSQASF
KSSAEYAAVREQFGLSIGKFEGIQEKLADIAGKTYLQEAMRVLTTEGLGLGLKPSVVTAIAKYHMTELGRNILESAMDIQ
AGKAIQCGPQNTLASAYVAQPIAITVEGANILTRNLMIFGQGVMRCHPHLQSMVETIHSNDKGADKKFNSILSKTIGYSV
GNSLRGFKLGLLPFTAAASSNLAEVKPYEQSVNKLASKLAVYADFSLLVLGGKLKQAEMLSARLGDVMSYLYAAMASIRY
YEKKLSAEQRKEAAPYFHYATRWSLCQAEKALLEFLDNFPSSATRKFMRLITVTYSAKMPKVNDDLVRELAKQAQLNTEF
KKNLTHLIKPVAGDGNDINEQAYLAKMACLPLLAKVKKALRARTFKAGVKFSLTLDAALEAKVITGDEHKQLQDYNLKRE
RAIRVDEFDFDMNLISDKPDLKIAN
>Mature_744_residues
SIRTQFRKILPTISTTEQEALDAGDVWLEGSIYQGVPDFAALREIPVATLSNDEQAFLDGPVATLLDMVDDFEIQQNKHL
PDNILNFLKENKFFSLIIPKSFGGLEFSPYANSTIVATIAAKSSAVAVTVMVPNSLGPGELLMHYGTSEQQDYWLPRLAN
GREIPCFALTSPEAGSDAGSIPDIGIVTMGEYQGEQVLGMNVTWDKRYITLSSIATVLGLAFKVEDPNGLLGGKEDLGIT
CALIPRSHQGVQLGNRHDPMGIRFYNGTTRGENVFIPMDFIIGGQKNIGRGWSMLVACLGAGRGISLPALGASVSQASFK
SSAEYAAVREQFGLSIGKFEGIQEKLADIAGKTYLQEAMRVLTTEGLGLGLKPSVVTAIAKYHMTELGRNILESAMDIQA
GKAIQCGPQNTLASAYVAQPIAITVEGANILTRNLMIFGQGVMRCHPHLQSMVETIHSNDKGADKKFNSILSKTIGYSVG
NSLRGFKLGLLPFTAAASSNLAEVKPYEQSVNKLASKLAVYADFSLLVLGGKLKQAEMLSARLGDVMSYLYAAMASIRYY
EKKLSAEQRKEAAPYFHYATRWSLCQAEKALLEFLDNFPSSATRKFMRLITVTYSAKMPKVNDDLVRELAKQAQLNTEFK
KNLTHLIKPVAGDGNDINEQAYLAKMACLPLLAKVKKALRARTFKAGVKFSLTLDAALEAKVITGDEHKQLQDYNLKRER
AIRVDEFDFDMNLISDKPDLKIAN

Specific function: Catalyzes the dehydrogenation of acyl-CoA [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361497, Length=369, Percent_Identity=31.7073170731707, Blast_Score=133, Evalue=7e-31,
Organism=Homo sapiens, GI4557235, Length=369, Percent_Identity=26.0162601626016, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI4557233, Length=317, Percent_Identity=29.9684542586751, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI76496475, Length=369, Percent_Identity=26.0162601626016, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI4501859, Length=369, Percent_Identity=25.7452574525745, Blast_Score=85, Evalue=3e-16,
Organism=Escherichia coli, GI87081702, Length=732, Percent_Identity=46.9945355191257, Blast_Score=643, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17506239, Length=335, Percent_Identity=27.7611940298507, Blast_Score=102, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17508101, Length=340, Percent_Identity=27.9411764705882, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71985184, Length=397, Percent_Identity=24.6851385390428, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI71985192, Length=317, Percent_Identity=25.2365930599369, Blast_Score=90, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI32563615, Length=248, Percent_Identity=29.0322580645161, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI71990804, Length=281, Percent_Identity=26.6903914590747, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17538396, Length=277, Percent_Identity=25.9927797833935, Blast_Score=71, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71982178, Length=264, Percent_Identity=25, Blast_Score=66, Evalue=8e-11,
Organism=Drosophila melanogaster, GI281363737, Length=391, Percent_Identity=26.8542199488491, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI21356377, Length=292, Percent_Identity=29.7945205479452, Blast_Score=95, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24666513, Length=338, Percent_Identity=28.698224852071, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24646207, Length=312, Percent_Identity=27.5641025641026, Blast_Score=86, Evalue=8e-17,
Organism=Drosophila melanogaster, GI21355753, Length=309, Percent_Identity=26.537216828479, Blast_Score=70, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100
- InterPro:   IPR015396 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N; PF09317 DUF1974 [H]

EC number: NA

Molecular weight: Translated: 81390; Mature: 81259

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIRTQFRKILPTISTTEQEALDAGDVWLEGSIYQGVPDFAALREIPVATLSNDEQAFLD
CCHHHHHHHHCCCCCCCHHHHCCCCCEEECCCHHCCCCCHHHHHHCCCEECCCCCHHHHC
GPVATLLDMVDDFEIQQNKHLPDNILNFLKENKFFSLIIPKSFGGLEFSPYANSTIVATI
CHHHHHHHHHHCHHHCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCEECCCCCCEEEEEE
AAKSSAVAVTVMVPNSLGPGELLMHYGTSEQQDYWLPRLANGREIPCFALTSPEAGSDAG
EECCCEEEEEEEECCCCCCCHHHEECCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCC
SIPDIGIVTMGEYQGEQVLGMNVTWDKRYITLSSIATVLGLAFKVEDPNGLLGGKEDLGI
CCCCCEEEEECCCCCCEEEEEEEEECCCEEEHHHHHHHHHEEEEECCCCCCCCCCCCCCE
TCALIPRSHQGVQLGNRHDPMGIRFYNGTTRGENVFIPMDFIIGGQKNIGRGWSMLVACL
EEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEEHEEECCCCCCCCHHHHHHHHH
GAGRGISLPALGASVSQASFKSSAEYAAVREQFGLSIGKFEGIQEKLADIAGKTYLQEAM
CCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
RVLTTEGLGLGLKPSVVTAIAKYHMTELGRNILESAMDIQAGKAIQCGPQNTLASAYVAQ
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHCC
PIAITVEGANILTRNLMIFGQGVMRCHPHLQSMVETIHSNDKGADKKFNSILSKTIGYSV
CEEEEEECCHHHHHHHHEECCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
GNSLRGFKLGLLPFTAAASSNLAEVKPYEQSVNKLASKLAVYADFSLLVLGGKLKQAEML
CCCCCCEEEECEEEHHHCCCCCHHCCCHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHH
SARLGDVMSYLYAAMASIRYYEKKLSAEQRKEAAPYFHYATRWSLCQAEKALLEFLDNFP
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHCCC
SSATRKFMRLITVTYSAKMPKVNDDLVRELAKQAQLNTEFKKNLTHLIKPVAGDGNDINE
CHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCH
QAYLAKMACLPLLAKVKKALRARTFKAGVKFSLTLDAALEAKVITGDEHKQLQDYNLKRE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEEECCCHHHHHHCCCCHH
RAIRVDEFDFDMNLISDKPDLKIAN
HCCEEECCCCCCCEECCCCCCEECC
>Mature Secondary Structure 
SIRTQFRKILPTISTTEQEALDAGDVWLEGSIYQGVPDFAALREIPVATLSNDEQAFLD
CHHHHHHHHCCCCCCCHHHHCCCCCEEECCCHHCCCCCHHHHHHCCCEECCCCCHHHHC
GPVATLLDMVDDFEIQQNKHLPDNILNFLKENKFFSLIIPKSFGGLEFSPYANSTIVATI
CHHHHHHHHHHCHHHCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCEECCCCCCEEEEEE
AAKSSAVAVTVMVPNSLGPGELLMHYGTSEQQDYWLPRLANGREIPCFALTSPEAGSDAG
EECCCEEEEEEEECCCCCCCHHHEECCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCC
SIPDIGIVTMGEYQGEQVLGMNVTWDKRYITLSSIATVLGLAFKVEDPNGLLGGKEDLGI
CCCCCEEEEECCCCCCEEEEEEEEECCCEEEHHHHHHHHHEEEEECCCCCCCCCCCCCCE
TCALIPRSHQGVQLGNRHDPMGIRFYNGTTRGENVFIPMDFIIGGQKNIGRGWSMLVACL
EEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEEHEEECCCCCCCCHHHHHHHHH
GAGRGISLPALGASVSQASFKSSAEYAAVREQFGLSIGKFEGIQEKLADIAGKTYLQEAM
CCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
RVLTTEGLGLGLKPSVVTAIAKYHMTELGRNILESAMDIQAGKAIQCGPQNTLASAYVAQ
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHCC
PIAITVEGANILTRNLMIFGQGVMRCHPHLQSMVETIHSNDKGADKKFNSILSKTIGYSV
CEEEEEECCHHHHHHHHEECCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
GNSLRGFKLGLLPFTAAASSNLAEVKPYEQSVNKLASKLAVYADFSLLVLGGKLKQAEML
CCCCCCEEEECEEEHHHCCCCCHHCCCHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHH
SARLGDVMSYLYAAMASIRYYEKKLSAEQRKEAAPYFHYATRWSLCQAEKALLEFLDNFP
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHCCC
SSATRKFMRLITVTYSAKMPKVNDDLVRELAKQAQLNTEFKKNLTHLIKPVAGDGNDINE
CHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCH
QAYLAKMACLPLLAKVKKALRARTFKAGVKFSLTLDAALEAKVITGDEHKQLQDYNLKRE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEEECCCHHHHHHCCCCHH
RAIRVDEFDFDMNLISDKPDLKIAN
HCCEEECCCCCCCEECCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]