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The map label for this gene is kefC [H]

Identifier: 167623193

GI number: 167623193

Start: 1532532

End: 1534460

Strand: Reverse

Name: kefC [H]

Synonym: Shal_1259

Alternate gene names: 167623193

Gene position: 1534460-1532532 (Counterclockwise)

Preceding gene: 167623194

Following gene: 167623191

Centisome position: 29.36

GC content: 47.85

Gene sequence:

>1929_bases
ATGACAGCTTATTTTATTCAAGCTTTTATCTATTTATGCGCCGCAGTTATCGCTGTACCCATCGCCAAAAGACTCGGCCT
AGGCTCAGTACTGGGCTACTTAATGGCAGGCGTTGTAATAGGCCCTATTATTGGCCTAGTCGGTGCTGAAACCAACACAC
TGCAACATTTTGCCGAGTTTGGTGTGGTGATGATGCTATTCCTTGTGGGCCTTGAGCTTGAGCCTAAAATGCTGTGGAAT
ATGCGCAATAAACTGATCGGATTAGGTGGCCTGCAGGTGGGTCTATCTACGCTTGTGGTTATGGGGATAGCCCTGAGTTT
CAACTATGGCTGGAGTATCGCCCTAACCGTGGGAATGATTTTTTCGCTGTCATCGACCGCCATCGTACTGCAGACCTTTA
ATGAAAAGAGTCTTACCAAAACAGAAGGTGGCAAAAACGCTTTCTCAGTACTGCTGTTTCAAGATATCGCCGTCATTCCT
ATGCTGGCATTTATCCCGCTGCTAGCTTTACCCGAGTTAGTCGAAAAGGCGCAGTCCGTTACACAAAGCGCCGCCGAGCA
CCACGATGAGCTGTCGTTAGTAGCGGGGCTACCGGGATGGGCATACGGTATTGTTGTATTAATGGCTATTGCCAGCGTTG
TGGTTGGCGGCCACTACTTAAGTCGTCCGCTATTTCGCTATGTTGCCAGTTCGGGACTGAGAGAGATCTTTACCGCAACC
GCACTGATGCTCGTTATCGGCATTGCCGCGCTCATGAGCCTTGTGGGTTTGTCTCCCGCGCTAGGCACCTTTCTTGCAGG
CGTTGTGCTGGCTAACAGTGAGTTTAGGCACGAGCTTGAGTCCAATATCGAACCATTTAAGGGGCTATTACTCGGGCTAT
TTTTTATCACCGTGGGCGCAGGCATAAACTTTGACGTACTCCTTAGTCATATCGGCCCGGTGATGGCTATGACGTCTGGC
GTGATATTAATAAAGGCTTCCGTACTGTTAGTGCTGGCCTTTATTTTTAAGATCAGGGGCAGCGACCGTTGGCTATTTGC
CCTGAGCCTAGCGCAAGCCGGTGAATTTGGCTTCGTGCTACTTAGCTATACCGTGCAAAACCATGTTATCACCAATGAAC
TCGCGCAGTTGCTGTCACTGGTTGTGGCCATCTCTATGTTCCTCACACCGGGGCTATTTATTCTATTCGATAAAGTCATA
CTGCCTCGCTATGAAAAAAACGAGAATACTCGCGAGCCCGATGATATTGATGAAAAAGGCACCGTGATTATTGCGGGTGT
TGGCCGCTTTGGGCAGATAGTTAATCGTTTATTAGTGACCAATGGTGTGAAAACCATAGTACTGGATCATGAAGTTCAGC
AAGTCGAAAACTTAAGGAAAATTAACACCAAGAGCTATTATGGTGACGCCACCCAGCCCGACTTGCTCCATACCGCAGGC
ATTGAACAGGCTAAGATGTTAGTCATCGCCATAGATGATCCTGAGCGCGCTGTTGGCTTAGTTGAATATATCAAACATAC
CTATCCTCACATTATTATCATGGCTCGTGCTTTTGACCGAAGGCACCTCTATCGCCTGCGTAACGCAGGAGCTGATTTTA
TGGTGAGTGAGACCTTCCATTCGGCGCTCAACCTAGGTAAGCATGCGCTGATAAGATTAGGTGTACATCCGTTCAAGGCC
GAGCAGCAGCGGGCAACCTTTTATGAGACGGAAACCACCCATAAAGACACCCTGTATGAGGCATGGAAACAGTTTACTGA
AGACGATAAGTATCTAGTCCATTACCGTGATATGTTCATTCAACTTGAAGAAACGCTAAGTGCAGCGATGAAAGATGAGC
GCTATCGCAGTTTCTCAAAAGTGGAGCGTAGCTGGACTCCACCGCCTAAAGAAAATCATACTGAGTTTTCAAAGGCGGAA
AGCGATTAG

Upstream 100 bases:

>100_bases
GAACACTCAGGGCACTCAGTGAGGACAGATTCGATATCGAGTTCGCGCAATCGCTCGAAAAACTCAATGGCCATCTAGAC
CAACTGATCAGGGAGCACTA

Downstream 100 bases:

>100_bases
CGTCGCGCTAACAAGAAGCGGCATAGTCATCAAGCTGTGCCTTTTCGACTAGCAATGGTTCCAGATATTGAACTACTACA
TTGTTGAAACTAGAAATCGG

Product: potassium efflux system protein

Products: Proton [Cytoplasm]; K (I) [Periplasm] [C]

Alternate protein names: K(+)/H(+) antiporter [H]

Number of amino acids: Translated: 642; Mature: 641

Protein sequence:

>642_residues
MTAYFIQAFIYLCAAVIAVPIAKRLGLGSVLGYLMAGVVIGPIIGLVGAETNTLQHFAEFGVVMMLFLVGLELEPKMLWN
MRNKLIGLGGLQVGLSTLVVMGIALSFNYGWSIALTVGMIFSLSSTAIVLQTFNEKSLTKTEGGKNAFSVLLFQDIAVIP
MLAFIPLLALPELVEKAQSVTQSAAEHHDELSLVAGLPGWAYGIVVLMAIASVVVGGHYLSRPLFRYVASSGLREIFTAT
ALMLVIGIAALMSLVGLSPALGTFLAGVVLANSEFRHELESNIEPFKGLLLGLFFITVGAGINFDVLLSHIGPVMAMTSG
VILIKASVLLVLAFIFKIRGSDRWLFALSLAQAGEFGFVLLSYTVQNHVITNELAQLLSLVVAISMFLTPGLFILFDKVI
LPRYEKNENTREPDDIDEKGTVIIAGVGRFGQIVNRLLVTNGVKTIVLDHEVQQVENLRKINTKSYYGDATQPDLLHTAG
IEQAKMLVIAIDDPERAVGLVEYIKHTYPHIIIMARAFDRRHLYRLRNAGADFMVSETFHSALNLGKHALIRLGVHPFKA
EQQRATFYETETTHKDTLYEAWKQFTEDDKYLVHYRDMFIQLEETLSAAMKDERYRSFSKVERSWTPPPKENHTEFSKAE
SD

Sequences:

>Translated_642_residues
MTAYFIQAFIYLCAAVIAVPIAKRLGLGSVLGYLMAGVVIGPIIGLVGAETNTLQHFAEFGVVMMLFLVGLELEPKMLWN
MRNKLIGLGGLQVGLSTLVVMGIALSFNYGWSIALTVGMIFSLSSTAIVLQTFNEKSLTKTEGGKNAFSVLLFQDIAVIP
MLAFIPLLALPELVEKAQSVTQSAAEHHDELSLVAGLPGWAYGIVVLMAIASVVVGGHYLSRPLFRYVASSGLREIFTAT
ALMLVIGIAALMSLVGLSPALGTFLAGVVLANSEFRHELESNIEPFKGLLLGLFFITVGAGINFDVLLSHIGPVMAMTSG
VILIKASVLLVLAFIFKIRGSDRWLFALSLAQAGEFGFVLLSYTVQNHVITNELAQLLSLVVAISMFLTPGLFILFDKVI
LPRYEKNENTREPDDIDEKGTVIIAGVGRFGQIVNRLLVTNGVKTIVLDHEVQQVENLRKINTKSYYGDATQPDLLHTAG
IEQAKMLVIAIDDPERAVGLVEYIKHTYPHIIIMARAFDRRHLYRLRNAGADFMVSETFHSALNLGKHALIRLGVHPFKA
EQQRATFYETETTHKDTLYEAWKQFTEDDKYLVHYRDMFIQLEETLSAAMKDERYRSFSKVERSWTPPPKENHTEFSKAE
SD
>Mature_641_residues
TAYFIQAFIYLCAAVIAVPIAKRLGLGSVLGYLMAGVVIGPIIGLVGAETNTLQHFAEFGVVMMLFLVGLELEPKMLWNM
RNKLIGLGGLQVGLSTLVVMGIALSFNYGWSIALTVGMIFSLSSTAIVLQTFNEKSLTKTEGGKNAFSVLLFQDIAVIPM
LAFIPLLALPELVEKAQSVTQSAAEHHDELSLVAGLPGWAYGIVVLMAIASVVVGGHYLSRPLFRYVASSGLREIFTATA
LMLVIGIAALMSLVGLSPALGTFLAGVVLANSEFRHELESNIEPFKGLLLGLFFITVGAGINFDVLLSHIGPVMAMTSGV
ILIKASVLLVLAFIFKIRGSDRWLFALSLAQAGEFGFVLLSYTVQNHVITNELAQLLSLVVAISMFLTPGLFILFDKVIL
PRYEKNENTREPDDIDEKGTVIIAGVGRFGQIVNRLLVTNGVKTIVLDHEVQQVENLRKINTKSYYGDATQPDLLHTAGI
EQAKMLVIAIDDPERAVGLVEYIKHTYPHIIIMARAFDRRHLYRLRNAGADFMVSETFHSALNLGKHALIRLGVHPFKAE
QQRATFYETETTHKDTLYEAWKQFTEDDKYLVHYRDMFIQLEETLSAAMKDERYRSFSKVERSWTPPPKENHTEFSKAES
D

Specific function: Transport system that facilitates potassium-efflux, possibly by potassium-proton antiport [H]

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI157388921, Length=426, Percent_Identity=27.4647887323944, Blast_Score=87, Evalue=3e-17,
Organism=Escherichia coli, GI1786232, Length=568, Percent_Identity=46.1267605633803, Blast_Score=459, Evalue=1e-130,
Organism=Escherichia coli, GI1789749, Length=615, Percent_Identity=41.1382113821138, Blast_Score=434, Evalue=1e-123,
Organism=Escherichia coli, GI1786685, Length=527, Percent_Identity=26.7552182163188, Blast_Score=149, Evalue=4e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771
- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR003148 [H]

Pfam domain/function: PF00999 Na_H_Exchanger; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 70833; Mature: 70702

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAYFIQAFIYLCAAVIAVPIAKRLGLGSVLGYLMAGVVIGPIIGLVGAETNTLQHFAEF
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
GVVMMLFLVGLELEPKMLWNMRNKLIGLGGLQVGLSTLVVMGIALSFNYGWSIALTVGMI
HHHHHHHHHCCCCCHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
FSLSSTAIVLQTFNEKSLTKTEGGKNAFSVLLFQDIAVIPMLAFIPLLALPELVEKAQSV
HHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQSAAEHHDELSLVAGLPGWAYGIVVLMAIASVVVGGHYLSRPLFRYVASSGLREIFTAT
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
ALMLVIGIAALMSLVGLSPALGTFLAGVVLANSEFRHELESNIEPFKGLLLGLFFITVGA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHCC
GINFDVLLSHIGPVMAMTSGVILIKASVLLVLAFIFKIRGSDRWLFALSLAQAGEFGFVL
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHCCCCCCEEE
LSYTVQNHVITNELAQLLSLVVAISMFLTPGLFILFDKVILPRYEKNENTREPDDIDEKG
EEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
TVIIAGVGRFGQIVNRLLVTNGVKTIVLDHEVQQVENLRKINTKSYYGDATQPDLLHTAG
CEEEEECCHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCC
IEQAKMLVIAIDDPERAVGLVEYIKHTYPHIIIMARAFDRRHLYRLRNAGADFMVSETFH
CCCEEEEEEEECCCHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHCCCCCHHHHHHHH
SALNLGKHALIRLGVHPFKAEQQRATFYETETTHKDTLYEAWKQFTEDDKYLVHYRDMFI
HHHHHCHHHHHHCCCCCCCCHHHHHHHEECCCCCHHHHHHHHHHHCCCCCEEHHHHHHHH
QLEETLSAAMKDERYRSFSKVERSWTPPPKENHTEFSKAESD
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TAYFIQAFIYLCAAVIAVPIAKRLGLGSVLGYLMAGVVIGPIIGLVGAETNTLQHFAEF
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
GVVMMLFLVGLELEPKMLWNMRNKLIGLGGLQVGLSTLVVMGIALSFNYGWSIALTVGMI
HHHHHHHHHCCCCCHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
FSLSSTAIVLQTFNEKSLTKTEGGKNAFSVLLFQDIAVIPMLAFIPLLALPELVEKAQSV
HHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQSAAEHHDELSLVAGLPGWAYGIVVLMAIASVVVGGHYLSRPLFRYVASSGLREIFTAT
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
ALMLVIGIAALMSLVGLSPALGTFLAGVVLANSEFRHELESNIEPFKGLLLGLFFITVGA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHCC
GINFDVLLSHIGPVMAMTSGVILIKASVLLVLAFIFKIRGSDRWLFALSLAQAGEFGFVL
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHCCCCCCEEE
LSYTVQNHVITNELAQLLSLVVAISMFLTPGLFILFDKVILPRYEKNENTREPDDIDEKG
EEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
TVIIAGVGRFGQIVNRLLVTNGVKTIVLDHEVQQVENLRKINTKSYYGDATQPDLLHTAG
CEEEEECCHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCC
IEQAKMLVIAIDDPERAVGLVEYIKHTYPHIIIMARAFDRRHLYRLRNAGADFMVSETFH
CCCEEEEEEEECCCHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHCCCCCHHHHHHHH
SALNLGKHALIRLGVHPFKAEQQRATFYETETTHKDTLYEAWKQFTEDDKYLVHYRDMFI
HHHHHCHHHHHHCCCCCCCCHHHHHHHEECCCCCHHHHHHHHHHHCCCCCEEHHHHHHHH
QLEETLSAAMKDERYRSFSKVERSWTPPPKENHTEFSKAESD
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Cytoplasm] = Proton [Cytoplasm] + K (I) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA