Click here to switch to the map view.

The map label for this gene is ltaE [H]

Identifier: 167623121

GI number: 167623121

Start: 1438422

End: 1439438

Strand: Direct

Name: ltaE [H]

Synonym: Shal_1187

Alternate gene names: 167623121

Gene position: 1438422-1439438 (Clockwise)

Preceding gene: 167623119

Following gene: 167623124

Centisome position: 27.52

GC content: 47.3

Gene sequence:

>1017_bases
ATGATTGATTTTCGCAGTGATACGGTCACTAAGCCTACGGCAGCTATGCGCGTCGCGATTAGTCAGGCTGAAGTTGGGGA
TGATGTTTATGGCGATGACCCAAGTGTTAACTATCTTGAAGAGATGGCAGCTGAAATGTTTGGCTATGACAATGCACTAT
TTACCTCTTCAGGGACTCAAGCAAACTTGCTTGCATTAATGGGACATTGCGAGCGTGGTGACGAATATCTATGCGGCCAA
CAGGCACATAACTATAAGTTTGAGGGCGGCGGTGCGGCAGTGCTAGGCAGTATTCAGCCTCAACCTTTAACCAATCAGGC
TGATGGCAGCATTCTTTTAAGCGATATCGAAGCTGCGATTAAACCTGACGATATCCACTTTGCACGTACACGTTTACTGA
GCTTAGAAAACACCATCGGCGGTAAGATAGTGCCGCAGGAGTACTTGGCTTCGGCACAGGCATTAGCTTTCGAGCGCGGT
TTGAAAATTCACCTCGATGGTGCACGCGTGGCTAACGCTGCAGTGGCGCAAAATATACCTATGACCGCCATTACTCAGTA
TTTTGACTCGGTATCTATCTGTCTTTCTAAGGGATTATGTGCCCCTGTAGGCTCAATACTATTGGGTGATGAACGCCTAA
TTACCAAGGCGAGACGCTGGCGTAAGGTATTAGGTGGCGGTATGCGTCAAGCTGGTATTCTAGCGTCTGCAGCTACGCTT
GCGTTAACCGAACAGGTTGAGCGCTTAGCTGAGGATCACGATAATGCTGCTTATCTAGCTGCGGAGCTTGCAACTATTGA
AGGCTTCGAGGTCGATATGTCACAAGTGCAGACCAATATGGTGTTTGCAGTGGTGAGTGACAAAATAGATACTAAAGCGC
TCGCGCTTGAGCTAAAGGCTAAAGGTATTTTACTGAGCCCAGGTAAAACGATCCGCTTGGTGACTCATGCCGATATTTCT
AGAGCCAATATCACGCACTTTATTAGCGAATTAAAGGGACTGCTAAAAGGCTGTTAA

Upstream 100 bases:

>100_bases
ATGTTTGTAAACTTTACATTTTGAACTGGTAGTTCATTACACTCCGCAGTAATATTGCCCTTTGTTTGATAATTCCAGAA
TTAGATACTTGAGGTTAACA

Downstream 100 bases:

>100_bases
TCCGCGATTACTTATCTTAAATATAAAAAACCTAGGCTAAGCCTAGGTTTTTGTTTTTAGTCACAAACTTGAGTTGGCAG
TTATTATCAACCGGATTTAA

Product: threonine aldolase

Products: NA

Alternate protein names: Low-specificity L-TA [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MIDFRSDTVTKPTAAMRVAISQAEVGDDVYGDDPSVNYLEEMAAEMFGYDNALFTSSGTQANLLALMGHCERGDEYLCGQ
QAHNYKFEGGGAAVLGSIQPQPLTNQADGSILLSDIEAAIKPDDIHFARTRLLSLENTIGGKIVPQEYLASAQALAFERG
LKIHLDGARVANAAVAQNIPMTAITQYFDSVSICLSKGLCAPVGSILLGDERLITKARRWRKVLGGGMRQAGILASAATL
ALTEQVERLAEDHDNAAYLAAELATIEGFEVDMSQVQTNMVFAVVSDKIDTKALALELKAKGILLSPGKTIRLVTHADIS
RANITHFISELKGLLKGC

Sequences:

>Translated_338_residues
MIDFRSDTVTKPTAAMRVAISQAEVGDDVYGDDPSVNYLEEMAAEMFGYDNALFTSSGTQANLLALMGHCERGDEYLCGQ
QAHNYKFEGGGAAVLGSIQPQPLTNQADGSILLSDIEAAIKPDDIHFARTRLLSLENTIGGKIVPQEYLASAQALAFERG
LKIHLDGARVANAAVAQNIPMTAITQYFDSVSICLSKGLCAPVGSILLGDERLITKARRWRKVLGGGMRQAGILASAATL
ALTEQVERLAEDHDNAAYLAAELATIEGFEVDMSQVQTNMVFAVVSDKIDTKALALELKAKGILLSPGKTIRLVTHADIS
RANITHFISELKGLLKGC
>Mature_338_residues
MIDFRSDTVTKPTAAMRVAISQAEVGDDVYGDDPSVNYLEEMAAEMFGYDNALFTSSGTQANLLALMGHCERGDEYLCGQ
QAHNYKFEGGGAAVLGSIQPQPLTNQADGSILLSDIEAAIKPDDIHFARTRLLSLENTIGGKIVPQEYLASAQALAFERG
LKIHLDGARVANAAVAQNIPMTAITQYFDSVSICLSKGLCAPVGSILLGDERLITKARRWRKVLGGGMRQAGILASAATL
ALTEQVERLAEDHDNAAYLAAELATIEGFEVDMSQVQTNMVFAVVSDKIDTKALALELKAKGILLSPGKTIRLVTHADIS
RANITHFISELKGLLKGC

Specific function: Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde. L-threo-phenylserine and L- erythro-phenylserine are also good substrates [H]

COG id: COG2008

COG function: function code E; Threonine aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1787095, Length=335, Percent_Identity=53.7313432835821, Blast_Score=363, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI193206522, Length=345, Percent_Identity=41.7391304347826, Blast_Score=246, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI193206520, Length=345, Percent_Identity=41.7391304347826, Blast_Score=246, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI193206524, Length=345, Percent_Identity=41.7391304347826, Blast_Score=246, Evalue=2e-65,
Organism=Saccharomyces cerevisiae, GI6320789, Length=283, Percent_Identity=39.5759717314488, Blast_Score=193, Evalue=3e-50,
Organism=Drosophila melanogaster, GI21355439, Length=299, Percent_Identity=44.1471571906354, Blast_Score=239, Evalue=2e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001597
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01212 Beta_elim_lyase [H]

EC number: =4.1.2.5 [H]

Molecular weight: Translated: 36199; Mature: 36199

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDFRSDTVTKPTAAMRVAISQAEVGDDVYGDDPSVNYLEEMAAEMFGYDNALFTSSGTQ
CCCCCCCCCCCCHHHHHEEHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCC
ANLLALMGHCERGDEYLCGQQAHNYKFEGGGAAVLGSIQPQPLTNQADGSILLSDIEAAI
HHHHHHHHCCCCCCCCCCCCCCCCEEECCCCEEEEECCCCCCCCCCCCCCEEEECHHHHC
KPDDIHFARTRLLSLENTIGGKIVPQEYLASAQALAFERGLKIHLDGARVANAAVAQNIP
CCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHCCCC
MTAITQYFDSVSICLSKGLCAPVGSILLGDERLITKARRWRKVLGGGMRQAGILASAATL
HHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
ALTEQVERLAEDHDNAAYLAAELATIEGFEVDMSQVQTNMVFAVVSDKIDTKALALELKA
HHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHEEEEEECCCCCCHHEEEEEEE
KGILLSPGKTIRLVTHADISRANITHFISELKGLLKGC
CEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIDFRSDTVTKPTAAMRVAISQAEVGDDVYGDDPSVNYLEEMAAEMFGYDNALFTSSGTQ
CCCCCCCCCCCCHHHHHEEHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCC
ANLLALMGHCERGDEYLCGQQAHNYKFEGGGAAVLGSIQPQPLTNQADGSILLSDIEAAI
HHHHHHHHCCCCCCCCCCCCCCCCEEECCCCEEEEECCCCCCCCCCCCCCEEEECHHHHC
KPDDIHFARTRLLSLENTIGGKIVPQEYLASAQALAFERGLKIHLDGARVANAAVAQNIP
CCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHCCCC
MTAITQYFDSVSICLSKGLCAPVGSILLGDERLITKARRWRKVLGGGMRQAGILASAATL
HHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
ALTEQVERLAEDHDNAAYLAAELATIEGFEVDMSQVQTNMVFAVVSDKIDTKALALELKA
HHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHEEEEEECCCCCCHHEEEEEEE
KGILLSPGKTIRLVTHADISRANITHFISELKGLLKGC
CEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]