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The map label for this gene is trpR [H]

Identifier: 167623045

GI number: 167623045

Start: 1350475

End: 1350750

Strand: Direct

Name: trpR [H]

Synonym: Shal_1111

Alternate gene names: 167623045

Gene position: 1350475-1350750 (Clockwise)

Preceding gene: 167623043

Following gene: 167623048

Centisome position: 25.84

GC content: 42.39

Gene sequence:

>276_bases
ATGCGAGCAGAATGGGGTTCCGTTTTAGAGAAAGTCTTATCGCATCAAGCGCATGACGATTTGATCGTATTGTTTGAGTT
GTTACTCACAGAGGAGGAGCGTAGTGCCGTGGCGGGGCGATTAAAGGTTTTTCAAACACTATTACAAGGCGAAATGAGTC
AGCGCCAAATCGCTCAAGAATACCAAATAAGTATCGCCACCATTACTCGCTGCTCTAATTATCTTAAGCATATGAGTTTG
CAGCAAAGAGACAATATTCAGCGGTTAATTTTATAG

Upstream 100 bases:

>100_bases
AAACTAATAATTTATAACAAGTGCATGGTGCGGCGCATTCTTGATACAATGCGCGTAATGACGCACTAGTACGTGATGAT
AGTTGTAAATAGGAGATAAA

Downstream 100 bases:

>100_bases
ACGTCCAACAGCTTGGCTCAACTAGGATTGTTACTGCCTGTAGTCGCTATCTGCTATCGATTATGGGTGTTACCGATATC
TTCTAGTCGTTGCAAAGTGA

Product: Trp operon repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 91; Mature: 91

Protein sequence:

>91_residues
MRAEWGSVLEKVLSHQAHDDLIVLFELLLTEEERSAVAGRLKVFQTLLQGEMSQRQIAQEYQISIATITRCSNYLKHMSL
QQRDNIQRLIL

Sequences:

>Translated_91_residues
MRAEWGSVLEKVLSHQAHDDLIVLFELLLTEEERSAVAGRLKVFQTLLQGEMSQRQIAQEYQISIATITRCSNYLKHMSL
QQRDNIQRLIL
>Mature_91_residues
MRAEWGSVLEKVLSHQAHDDLIVLFELLLTEEERSAVAGRLKVFQTLLQGEMSQRQIAQEYQISIATITRCSNYLKHMSL
QQRDNIQRLIL

Specific function: This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription [H]

COG id: COG2973

COG function: function code K; Trp operon repressor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpR family [H]

Homologues:

None

Paralogues:

None

Copy number: 250-750 50-300 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000831
- InterPro:   IPR013335
- InterPro:   IPR010921
- ProDom:   PD012582 [H]

Pfam domain/function: PF01371 Trp_repressor [H]

EC number: NA

Molecular weight: Translated: 10582; Mature: 10582

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAEWGSVLEKVLSHQAHDDLIVLFELLLTEEERSAVAGRLKVFQTLLQGEMSQRQIAQE
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
YQISIATITRCSNYLKHMSLQQRDNIQRLIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRAEWGSVLEKVLSHQAHDDLIVLFELLLTEEERSAVAGRLKVFQTLLQGEMSQRQIAQE
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
YQISIATITRCSNYLKHMSLQQRDNIQRLIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA