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The map label for this gene is pheA [H]

Identifier: 167623041

GI number: 167623041

Start: 1346059

End: 1348038

Strand: Reverse

Name: pheA [H]

Synonym: Shal_1107

Alternate gene names: 167623041

Gene position: 1348038-1346059 (Counterclockwise)

Preceding gene: 167623042

Following gene: 167623029

Centisome position: 25.79

GC content: 45.86

Gene sequence:

>1980_bases
ATGAGCAAACCACAACCCTTAAATCACACTCGAGAGCAGATCACGAGTCTCGATAATGAACTGCTGGCTCTGCTAGCAAA
GCGCAGAGAATTAAGCTTAGATGTAGCACGTAGCAAAGAGGTCGATGTGAGGCCTATTCGCGATACTATCCGCGAAAAAG
AGCTACTATCACGCTTGGTAAAACAGGGGCGTGAACAAGGCTTAGATGCCCACTATGTCATCTCACTCTATCAAAGCATC
ATCGAAGACTCTGTACTTAATCAACAAGCTTATTTACATGGGCGCGCTAACCCTGAAACTCAACAGCAGCAATACTGCAT
CGCCTACCTTGGCGCTAGAGGCTCTTATTCGTATCTAGCAGCTAGCCGCTATTGCAATAGACGCCAGGTCGAGATGCAGG
ATTTAGGCTGCCAAAGCTTCGATGAGATAGTACAGGCCGTTGAGTCTGGCCACGCCGATTATGGATTCCTTCCGATTGAA
AATACTTCCTCGGGCTCTATTAACGAGGTTTATGACGTACTACAGCACACCAGCCTTGCTATCGTTGGAGAAACCACCAT
TGAGGTCGGCCACTGCTTGCTGGCTAATAGCGGCAGCAATATTGCCGATATAAAAACAGTTTACGCCCATCCACAACCCA
TTAGCCAATGTAGCCGCTATTTGAGTCAGCGCAGCGAGTTCAAACTAGAATATTGCTCAAGTAGTGCCGAAGCGATGGAG
AAAGTCTGTAACGCAAACGATAGCAGTGTCGCGGCTATCGGTAGTGCCGAAGGTGGCGCCTTGTATCAATTAGAAGCGAT
TGAAACGGATCTCGCTAATCAAAAGGTTAATCAAAGCCGCTTTATCGTCGTTGCACGAAAGGCCGTTGAAGTACCTTCAC
AGCTTCCAGCAAAATGCACGCTGATCATGGCTACAGGGCAGAAGCCTGGAGCATTGGTTGAGGCCTTACTCGTATTAAAG
GCCCGTAACCTTAATATGAGTAAACTCGAATCCCGTCCGATCCCAGGTACTCCTTGGGAGGAGATGTTCTATTTAGATAT
CGATGCAAACCTCTCAAGCGAGCCGATGCAAGCAGCGCTAAAAGAACTGGAACGCACCACTCGCTTTATTAAAGTGCTCG
GTTGTTACCCTTGCGAAACGGTAAAACCGACTCAACTCAGTAATAGCCAGTTGATGATTGAGCCTAACACCTCTAAGTCG
ACCGCTGTTGCAGCAACAACCAGTAATAAGCAGCAACGCTTTAGTAAGCAATATAAGAGTGAAGCAACACAAGTCGTTTG
CGGCCAACTGGATCTTGGCAATGGAAATATCGGAGCCCTTGCCCAGATGCAACTCCCCATTGATCTTCTGCAGTTTGAAC
AGATGGCAAAGGAGCTTAAAGAGGCTGGTTTCCAAGCCGTTGCTATTCAAGGGTTAAGCCAACAAAGCGATGTGATTAAC
TCTATCGATAAATTTAAGCACGCTCTCGCTCAGTTTAATTTAGTTTGTGTCTTGGTAATCGAACATGAAACTGACTTAAC
TATGGCAACTCAGTTTGCGGATGTAGTAATGCTATCGGGCAACCTAATGTATAACCAGGCCATTTTAATCCAACTTGGCT
CTCTACTCGTTCCTGTTATCGTAGAGCGTAATACAATGGCTAGCGTCGATGATCTACTCAATGCCGCAGAAATAATTTTA
GGCCAAGGTAACCAACAGCTTATCTTGTGTGAATCGGGCGTCACAACCCTTAATAACTCAGGTAAACCATCACTGGATCT
GGCTGCATTGGTTGAGTTAAAAGCCCTAAGTCACTTACCTATTTTAGTCAATCCAAGCTATGCGATTGAGTCCGAGCAAA
TGCCCACATTCGTTAGGGCGATAAGACAGCTGAAAGGCGATGGTGTCATGGTGAATTTGAGCGCGATTGAGCATGCATCA
AAAGCTGACACAGCAGAACTAATTAATAAGATTTTGAGCAGTTTATACCAATCACATTAA

Upstream 100 bases:

>100_bases
CACATGGGAGGCTTTTTTATATCGGCTAAGATGAGCATACGTTAGCATGCTTATCACTAAGGTATTAATACTAAGCGCAA
TAGAAGAGTTAGAGGCGAAG

Downstream 100 bases:

>100_bases
ATATGTGATCATTCAACGGGAAACTGGTTCTCCTTCTGATATTAAGATTTACGCTGAGCAGCTTGCTCAGCGTTACTCTT
ATCAATCAAACTTGGAATCG

Product: chorismate mutase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 659; Mature: 658

Protein sequence:

>659_residues
MSKPQPLNHTREQITSLDNELLALLAKRRELSLDVARSKEVDVRPIRDTIREKELLSRLVKQGREQGLDAHYVISLYQSI
IEDSVLNQQAYLHGRANPETQQQQYCIAYLGARGSYSYLAASRYCNRRQVEMQDLGCQSFDEIVQAVESGHADYGFLPIE
NTSSGSINEVYDVLQHTSLAIVGETTIEVGHCLLANSGSNIADIKTVYAHPQPISQCSRYLSQRSEFKLEYCSSSAEAME
KVCNANDSSVAAIGSAEGGALYQLEAIETDLANQKVNQSRFIVVARKAVEVPSQLPAKCTLIMATGQKPGALVEALLVLK
ARNLNMSKLESRPIPGTPWEEMFYLDIDANLSSEPMQAALKELERTTRFIKVLGCYPCETVKPTQLSNSQLMIEPNTSKS
TAVAATTSNKQQRFSKQYKSEATQVVCGQLDLGNGNIGALAQMQLPIDLLQFEQMAKELKEAGFQAVAIQGLSQQSDVIN
SIDKFKHALAQFNLVCVLVIEHETDLTMATQFADVVMLSGNLMYNQAILIQLGSLLVPVIVERNTMASVDDLLNAAEIIL
GQGNQQLILCESGVTTLNNSGKPSLDLAALVELKALSHLPILVNPSYAIESEQMPTFVRAIRQLKGDGVMVNLSAIEHAS
KADTAELINKILSSLYQSH

Sequences:

>Translated_659_residues
MSKPQPLNHTREQITSLDNELLALLAKRRELSLDVARSKEVDVRPIRDTIREKELLSRLVKQGREQGLDAHYVISLYQSI
IEDSVLNQQAYLHGRANPETQQQQYCIAYLGARGSYSYLAASRYCNRRQVEMQDLGCQSFDEIVQAVESGHADYGFLPIE
NTSSGSINEVYDVLQHTSLAIVGETTIEVGHCLLANSGSNIADIKTVYAHPQPISQCSRYLSQRSEFKLEYCSSSAEAME
KVCNANDSSVAAIGSAEGGALYQLEAIETDLANQKVNQSRFIVVARKAVEVPSQLPAKCTLIMATGQKPGALVEALLVLK
ARNLNMSKLESRPIPGTPWEEMFYLDIDANLSSEPMQAALKELERTTRFIKVLGCYPCETVKPTQLSNSQLMIEPNTSKS
TAVAATTSNKQQRFSKQYKSEATQVVCGQLDLGNGNIGALAQMQLPIDLLQFEQMAKELKEAGFQAVAIQGLSQQSDVIN
SIDKFKHALAQFNLVCVLVIEHETDLTMATQFADVVMLSGNLMYNQAILIQLGSLLVPVIVERNTMASVDDLLNAAEIIL
GQGNQQLILCESGVTTLNNSGKPSLDLAALVELKALSHLPILVNPSYAIESEQMPTFVRAIRQLKGDGVMVNLSAIEHAS
KADTAELINKILSSLYQSH
>Mature_658_residues
SKPQPLNHTREQITSLDNELLALLAKRRELSLDVARSKEVDVRPIRDTIREKELLSRLVKQGREQGLDAHYVISLYQSII
EDSVLNQQAYLHGRANPETQQQQYCIAYLGARGSYSYLAASRYCNRRQVEMQDLGCQSFDEIVQAVESGHADYGFLPIEN
TSSGSINEVYDVLQHTSLAIVGETTIEVGHCLLANSGSNIADIKTVYAHPQPISQCSRYLSQRSEFKLEYCSSSAEAMEK
VCNANDSSVAAIGSAEGGALYQLEAIETDLANQKVNQSRFIVVARKAVEVPSQLPAKCTLIMATGQKPGALVEALLVLKA
RNLNMSKLESRPIPGTPWEEMFYLDIDANLSSEPMQAALKELERTTRFIKVLGCYPCETVKPTQLSNSQLMIEPNTSKST
AVAATTSNKQQRFSKQYKSEATQVVCGQLDLGNGNIGALAQMQLPIDLLQFEQMAKELKEAGFQAVAIQGLSQQSDVINS
IDKFKHALAQFNLVCVLVIEHETDLTMATQFADVVMLSGNLMYNQAILIQLGSLLVPVIVERNTMASVDDLLNAAEIILG
QGNQQLILCESGVTTLNNSGKPSLDLAALVELKALSHLPILVNPSYAIESEQMPTFVRAIRQLKGDGVMVNLSAIEHASK
ADTAELINKILSSLYQSH

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=386, Percent_Identity=54.6632124352332, Blast_Score=431, Evalue=1e-122,
Organism=Saccharomyces cerevisiae, GI6324013, Length=290, Percent_Identity=23.7931034482759, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010952
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 72340; Mature: 72209

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPQPLNHTREQITSLDNELLALLAKRRELSLDVARSKEVDVRPIRDTIREKELLSRLV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEHHCCCCCCCHHHHHHHHHHHHHHHHH
KQGREQGLDAHYVISLYQSIIEDSVLNQQAYLHGRANPETQQQQYCIAYLGARGSYSYLA
HHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHEECCCCCCHHHHHHHHHEECCCCCHHHHH
ASRYCNRRQVEMQDLGCQSFDEIVQAVESGHADYGFLPIENTSSGSINEVYDVLQHTSLA
HHHCCCCCCCHHHHCCCCHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHCCEE
IVGETTIEVGHCLLANSGSNIADIKTVYAHPQPISQCSRYLSQRSEFKLEYCSSSAEAME
EEECCHHHHCEEEEECCCCCCCHHHEEECCCCCHHHHHHHHHHHHCCCHHHHCCHHHHHH
KVCNANDSSVAAIGSAEGGALYQLEAIETDLANQKVNQSRFIVVARKAVEVPSQLPAKCT
HHHCCCCCCEEEEECCCCCCEEEEHHHHHHHHHCCCCCCEEEEEEHHHHCCCCCCCCEEE
LIMATGQKPGALVEALLVLKARNLNMSKLESRPIPGTPWEEMFYLDIDANLSSEPMQAAL
EEEECCCCCHHHHHHHHHHHHCCCCHHHHCCCCCCCCCHHHEEEEEECCCCCCCHHHHHH
KELERTTRFIKVLGCYPCETVKPTQLSNSQLMIEPNTSKSTAVAATTSNKQQRFSKQYKS
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEECCCHHHHHHHHHHH
EATQVVCGQLDLGNGNIGALAQMQLPIDLLQFEQMAKELKEAGFQAVAIQGLSQQSDVIN
HHHHEEECEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHH
SIDKFKHALAQFNLVCVLVIEHETDLTMATQFADVVMLSGNLMYNQAILIQLGSLLVPVI
HHHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHH
VERNTMASVDDLLNAAEIILGQGNQQLILCESGVTTLNNSGKPSLDLAALVELKALSHLP
CCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCC
ILVNPSYAIESEQMPTFVRAIRQLKGDGVMVNLSAIEHASKADTAELINKILSSLYQSH
EEECCCCCCCCCCCCHHHHHHHHHCCCCEEEEHHHHHCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKPQPLNHTREQITSLDNELLALLAKRRELSLDVARSKEVDVRPIRDTIREKELLSRLV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEHHCCCCCCCHHHHHHHHHHHHHHHHH
KQGREQGLDAHYVISLYQSIIEDSVLNQQAYLHGRANPETQQQQYCIAYLGARGSYSYLA
HHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHEECCCCCCHHHHHHHHHEECCCCCHHHHH
ASRYCNRRQVEMQDLGCQSFDEIVQAVESGHADYGFLPIENTSSGSINEVYDVLQHTSLA
HHHCCCCCCCHHHHCCCCHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHCCEE
IVGETTIEVGHCLLANSGSNIADIKTVYAHPQPISQCSRYLSQRSEFKLEYCSSSAEAME
EEECCHHHHCEEEEECCCCCCCHHHEEECCCCCHHHHHHHHHHHHCCCHHHHCCHHHHHH
KVCNANDSSVAAIGSAEGGALYQLEAIETDLANQKVNQSRFIVVARKAVEVPSQLPAKCT
HHHCCCCCCEEEEECCCCCCEEEEHHHHHHHHHCCCCCCEEEEEEHHHHCCCCCCCCEEE
LIMATGQKPGALVEALLVLKARNLNMSKLESRPIPGTPWEEMFYLDIDANLSSEPMQAAL
EEEECCCCCHHHHHHHHHHHHCCCCHHHHCCCCCCCCCHHHEEEEEECCCCCCCHHHHHH
KELERTTRFIKVLGCYPCETVKPTQLSNSQLMIEPNTSKSTAVAATTSNKQQRFSKQYKS
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEECCCHHHHHHHHHHH
EATQVVCGQLDLGNGNIGALAQMQLPIDLLQFEQMAKELKEAGFQAVAIQGLSQQSDVIN
HHHHEEECEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHH
SIDKFKHALAQFNLVCVLVIEHETDLTMATQFADVVMLSGNLMYNQAILIQLGSLLVPVI
HHHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHH
VERNTMASVDDLLNAAEIILGQGNQQLILCESGVTTLNNSGKPSLDLAALVELKALSHLP
CCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCC
ILVNPSYAIESEQMPTFVRAIRQLKGDGVMVNLSAIEHASKADTAELINKILSSLYQSH
EEECCCCCCCCCCCCHHHHHHHHHCCCCEEEEHHHHHCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]