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The map label for this gene is yjcE [H]

Identifier: 167623040

GI number: 167623040

Start: 1344731

End: 1346017

Strand: Direct

Name: yjcE [H]

Synonym: Shal_1106

Alternate gene names: 167623040

Gene position: 1344731-1346017 (Clockwise)

Preceding gene: 167623039

Following gene: 167623043

Centisome position: 25.73

GC content: 41.88

Gene sequence:

>1287_bases
GTGACCAGTTACGAAATCCTTTGTCTACTATCTGCACTTTCTCTTGTTATTTCGCTTATTTCATCACGATTACACCGCTG
GCAGCAAACCGTCACTATTACTGCACTGGCATTGTGTTTGAGCCTCGTTATTTTAGTTGCAGGTAAAATTTTCGGTATAA
AAATTTATTCAACCTTAGTGACTGATTTAGAACAACTTGATTTTAATGCTCTGCTGCTTAACGGCATGCTGGGCTTCTTA
CTGTTTGCTGGCACGTTGCAGATTAAGCTAAATATATTAAAAAAACAGAAGTGGGAAATTTTTATACTGGCTTTTGTTGG
CACACTGATATCAACATTTATTGTCGGTGGTCTGCTATATCTAGTCGCTTCTGTTATAGGTTTACCTTTAAATTTTAGTC
ATTGCCTACTATTTGGCGCACTGATTTCACCAACGGATCCGATTGCAGTACTGGCAATTATTAAACAGCTTGGTGCGCCG
GAAGATATTGCAACTCAGGTTGAGGGCGAATCGCTCTTCAATGACGGTATTGGTTTGGTGATTTTTATCACTGTTTCGCA
AGTGGCATTTTCAACTGAGCCGTTAACATTTATAGATGTGAGTAAGCTGTTTATTAGAGAAGCGTTGGGAGGTTTACTTT
ACGGTGCTGTATTAGCCGCCATATTACATGGCATGTTACGTTTTTCCGAAGAGCGGACTCAGTATTTACTGATGACATTA
TTGGTGCCGAGTGCTGGCTACATCGGAGCCGATTTGCTGGGAGTATCTGGGCCATTAGCCATGGTCGCAGCAGGAATTAT
CATAGGTAATCTGAGTGTGCCTAAGCTGCTAAAGGAAGAAGATCAAGGCCACCTAGAGAGCTTCTGGTTATTGATTGAGT
CATTCTTTAATTCGTTATTGTTCCTGCTGTTAGGCTTGCTATTGCTACTCATTCATTTCGATGTTGAGCTGTGGTGGTTT
ATGCTTCTTGCCGTCCCGATAGTGTTGATAGGGCGAGCTATCAGCATTTACCTGCCTTATTTAGGTTTTAGGCGTTTTAG
GCATTATAACTCCTATGCGGAAAAGATCTTGATTTGGGGAGGGCTCAGAGGTGGACTCGCACTTGCGATGGCGATGAGTT
TACCTACTGGTTTGATGATTATGAGTGACAGTAATATTGATCTGCGGGAGCTCTTAATGGTGATGACTTACGCGGTGGTG
GTTTTTTCTATTTTAGTCCAAGGGACGACGATTCCAAGTTTGATTGATAAGAGTAACGCTGAGCAAGCTGCTCAGCGTAA
ATCTTAA

Upstream 100 bases:

>100_bases
GGTTTAGTGGCAGGATCATCAAGGGGTGGCTCAGCTTAATTGAAGGTCGCAATATTTAACCTCTCCAATCGTCTCTCTTT
TTCCTTACCGAGAACTACTT

Downstream 100 bases:

>100_bases
TATCAGAAGGAGAACCAGTTTCCCGTTGAATGATCACATATTTAATGTGATTGGTATAAACTGCTCAAAATCTTATTAAT
TAGTTCTGCTGTGTCAGCTT

Product: sodium/hydrogen exchanger

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MTSYEILCLLSALSLVISLISSRLHRWQQTVTITALALCLSLVILVAGKIFGIKIYSTLVTDLEQLDFNALLLNGMLGFL
LFAGTLQIKLNILKKQKWEIFILAFVGTLISTFIVGGLLYLVASVIGLPLNFSHCLLFGALISPTDPIAVLAIIKQLGAP
EDIATQVEGESLFNDGIGLVIFITVSQVAFSTEPLTFIDVSKLFIREALGGLLYGAVLAAILHGMLRFSEERTQYLLMTL
LVPSAGYIGADLLGVSGPLAMVAAGIIIGNLSVPKLLKEEDQGHLESFWLLIESFFNSLLFLLLGLLLLLIHFDVELWWF
MLLAVPIVLIGRAISIYLPYLGFRRFRHYNSYAEKILIWGGLRGGLALAMAMSLPTGLMIMSDSNIDLRELLMVMTYAVV
VFSILVQGTTIPSLIDKSNAEQAAQRKS

Sequences:

>Translated_428_residues
MTSYEILCLLSALSLVISLISSRLHRWQQTVTITALALCLSLVILVAGKIFGIKIYSTLVTDLEQLDFNALLLNGMLGFL
LFAGTLQIKLNILKKQKWEIFILAFVGTLISTFIVGGLLYLVASVIGLPLNFSHCLLFGALISPTDPIAVLAIIKQLGAP
EDIATQVEGESLFNDGIGLVIFITVSQVAFSTEPLTFIDVSKLFIREALGGLLYGAVLAAILHGMLRFSEERTQYLLMTL
LVPSAGYIGADLLGVSGPLAMVAAGIIIGNLSVPKLLKEEDQGHLESFWLLIESFFNSLLFLLLGLLLLLIHFDVELWWF
MLLAVPIVLIGRAISIYLPYLGFRRFRHYNSYAEKILIWGGLRGGLALAMAMSLPTGLMIMSDSNIDLRELLMVMTYAVV
VFSILVQGTTIPSLIDKSNAEQAAQRKS
>Mature_427_residues
TSYEILCLLSALSLVISLISSRLHRWQQTVTITALALCLSLVILVAGKIFGIKIYSTLVTDLEQLDFNALLLNGMLGFLL
FAGTLQIKLNILKKQKWEIFILAFVGTLISTFIVGGLLYLVASVIGLPLNFSHCLLFGALISPTDPIAVLAIIKQLGAPE
DIATQVEGESLFNDGIGLVIFITVSQVAFSTEPLTFIDVSKLFIREALGGLLYGAVLAAILHGMLRFSEERTQYLLMTLL
VPSAGYIGADLLGVSGPLAMVAAGIIIGNLSVPKLLKEEDQGHLESFWLLIESFFNSLLFLLLGLLLLLIHFDVELWWFM
LLAVPIVLIGRAISIYLPYLGFRRFRHYNSYAEKILIWGGLRGGLALAMAMSLPTGLMIMSDSNIDLRELLMVMTYAVVV
FSILVQGTTIPSLIDKSNAEQAAQRKS

Specific function: Unknown

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family [H]

Homologues:

Organism=Homo sapiens, GI148727259, Length=338, Percent_Identity=26.0355029585799, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI294997330, Length=365, Percent_Identity=24.6575342465753, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI5454070, Length=356, Percent_Identity=24.7191011235955, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI110227626, Length=365, Percent_Identity=24.6575342465753, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI15529998, Length=339, Percent_Identity=26.2536873156342, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI14211919, Length=406, Percent_Identity=25.615763546798, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI27734935, Length=376, Percent_Identity=24.2021276595745, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI27777632, Length=328, Percent_Identity=29.5731707317073, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI194239733, Length=342, Percent_Identity=26.6081871345029, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI41872703, Length=451, Percent_Identity=27.4944567627494, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI4759144, Length=348, Percent_Identity=27.8735632183908, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1790501, Length=380, Percent_Identity=30.7894736842105, Blast_Score=96, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI71999819, Length=338, Percent_Identity=25.7396449704142, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71999817, Length=338, Percent_Identity=25.7396449704142, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71999821, Length=338, Percent_Identity=25.7396449704142, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71987535, Length=347, Percent_Identity=25.6484149855908, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71987537, Length=347, Percent_Identity=25.6484149855908, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71992107, Length=311, Percent_Identity=22.8295819935691, Blast_Score=95, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI71992101, Length=311, Percent_Identity=22.8295819935691, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71980847, Length=307, Percent_Identity=26.0586319218241, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI71990924, Length=305, Percent_Identity=26.2295081967213, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI71990932, Length=341, Percent_Identity=26.6862170087977, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25147678, Length=308, Percent_Identity=25.3246753246753, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25150332, Length=340, Percent_Identity=22.3529411764706, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71993582, Length=335, Percent_Identity=23.5820895522388, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71993590, Length=335, Percent_Identity=23.5820895522388, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI221510740, Length=342, Percent_Identity=25.4385964912281, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24585580, Length=342, Percent_Identity=25.4385964912281, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24585578, Length=342, Percent_Identity=25.4385964912281, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI281364513, Length=387, Percent_Identity=24.8062015503876, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI221473212, Length=390, Percent_Identity=25.6410256410256, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI221473215, Length=386, Percent_Identity=24.8704663212435, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI221473222, Length=386, Percent_Identity=24.8704663212435, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI221510734, Length=346, Percent_Identity=26.3005780346821, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI221510738, Length=346, Percent_Identity=26.3005780346821, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI281360447, Length=328, Percent_Identity=27.4390243902439, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI221510732, Length=353, Percent_Identity=25.7790368271955, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI221510736, Length=353, Percent_Identity=25.7790368271955, Blast_Score=85, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR018422
- InterPro:   IPR004705 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 46855; Mature: 46724

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSYEILCLLSALSLVISLISSRLHRWQQTVTITALALCLSLVILVAGKIFGIKIYSTLV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TDLEQLDFNALLLNGMLGFLLFAGTLQIKLNILKKQKWEIFILAFVGTLISTFIVGGLLY
HHHHHHCHHHHHHHHHHHHHHHHHHHHHEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LVASVIGLPLNFSHCLLFGALISPTDPIAVLAIIKQLGAPEDIATQVEGESLFNDGIGLV
HHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHCCCHHHHCCCCCEE
IFITVSQVAFSTEPLTFIDVSKLFIREALGGLLYGAVLAAILHGMLRFSEERTQYLLMTL
EEEEHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVPSAGYIGADLLGVSGPLAMVAAGIIIGNLSVPKLLKEEDQGHLESFWLLIESFFNSLL
HHCCCCCCCHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHH
FLLLGLLLLLIHFDVELWWFMLLAVPIVLIGRAISIYLPYLGFRRFRHYNSYAEKILIWG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEC
GLRGGLALAMAMSLPTGLMIMSDSNIDLRELLMVMTYAVVVFSILVQGTTIPSLIDKSNA
CCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCH
EQAAQRKS
HHHHHCCC
>Mature Secondary Structure 
TSYEILCLLSALSLVISLISSRLHRWQQTVTITALALCLSLVILVAGKIFGIKIYSTLV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TDLEQLDFNALLLNGMLGFLLFAGTLQIKLNILKKQKWEIFILAFVGTLISTFIVGGLLY
HHHHHHCHHHHHHHHHHHHHHHHHHHHHEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LVASVIGLPLNFSHCLLFGALISPTDPIAVLAIIKQLGAPEDIATQVEGESLFNDGIGLV
HHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHCCCHHHHCCCCCEE
IFITVSQVAFSTEPLTFIDVSKLFIREALGGLLYGAVLAAILHGMLRFSEERTQYLLMTL
EEEEHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVPSAGYIGADLLGVSGPLAMVAAGIIIGNLSVPKLLKEEDQGHLESFWLLIESFFNSLL
HHCCCCCCCHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHH
FLLLGLLLLLIHFDVELWWFMLLAVPIVLIGRAISIYLPYLGFRRFRHYNSYAEKILIWG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEC
GLRGGLALAMAMSLPTGLMIMSDSNIDLRELLMVMTYAVVVFSILVQGTTIPSLIDKSNA
CCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCH
EQAAQRKS
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]