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The map label for this gene is betA [H]

Identifier: 167622991

GI number: 167622991

Start: 1289763

End: 1291460

Strand: Reverse

Name: betA [H]

Synonym: Shal_1057

Alternate gene names: 167622991

Gene position: 1291460-1289763 (Counterclockwise)

Preceding gene: 167622992

Following gene: 167622990

Centisome position: 24.71

GC content: 50.65

Gene sequence:

>1698_bases
ATGACCATAACCAATCCACAATACGACTATATTATCGTTGGCGCTGGTAGCGCTGGTTGCGTGTTAGCTAACCGTTTATC
AGCCGACTCGAATAACCGCGTACTGCTGCTGGAAACTGGCGGCAGCGACAGGAGCATCTTTATTCAGATGCCTACCGCGC
TATCAATCCCGATGAATACTAAGAAGTACGCTTGGCAATTTGAAACCGATGCAGAGCCCTATCTAGACAACCGCCGTATG
CACTGTCCACGCGGCAAAGTATTGGGCGGCTCATCATCGATTAATGGCATGGTATATGTGCGCGGCCACGCTCGTGATTT
TGATGAGTGGCAAGAGCACGGTGCAAAAAACTGGGATTACGCCCACTGCCTACCTTACTTTAAGAAAGCCGAAGACTGGG
CATTTGGCGAGGATGATTATCGCGGTAACGATGGCCCACTTGGGGTCAACAACGGTAACGAGATGAAAAACCCGTTGTAT
AAAGCCTTTGTCGCCGCGGGTGTTGATGCTGGTTACCTCGCCACTGACGACTATAACGGTGCTCAGCAAGAGGGCTTTGG
CCCTATGCATATGACGGTTAAAAATGGCGTGCGTTGGTCAACGGCTAACGCCTACCTAAGACCAGCAATGCAGCGTGAAA
ACCTCACCGTGATCACCCACGCTCAGGTGCACAGGGTGCTGTTTTCAAGTAAACCTGGTGAAGCCAACAAAGTCGTGGGA
GTACGCTTTGAGCGTAAAGGAAAAATGCGTGAAGCTAACGCCAGCAAAGAGGTGATACTGTCTGCAGGTTCAATCGGCTC
GCCGCATATCCTACAGCTCTCAGGTATTGGCGCCAGCGATACCTTAGCCAAGGCTGGCATCGAGCAAGTACATGAGCTGC
CTGGTGTCGGTGAAAACCTGCAAGATCACCTCGAGTTTTACTTCCAGTTTAAGTGCCTTAAGCCAATATCGCTCAACGGT
AAACTCGACCCACTCAATAAGCTGTTTATTGGTACTCGCTGGATCTTAAACAGATCAGGGCTCGGCGCCACCAACCATTT
CGAGTCTTGCGGCTTTATCCGCTCAAAAGCGGGTCTCGAATGGCCCGATCTGCAATACCATTTTTTACCTGCAGCGATGC
GATATGACGGCAAAGAGGCCTTTGCAGGCCATGGTTTCCAAGTACACATTGGCCACAACAAACCTAAGAGTCGCGGCAGT
GTAAAAGTGGTTTCAAACGATCCCAAAGTCGCCCCAAGTATTTTGTTTAACTACCTATCTCATCAGGATGATATCGAAGG
CTTCCGTGCCTGCGTTCGCTTAACCCGTGAAATCATCAATCAACCCGCTCTGGATGAGTACCGCGGTGAAGAGATCCAGC
CCGGCACAGCAGTACAAACCGATCAGCAGATAGATAGCTTTGTAAGAAGCACGGTCGAGAGCGCCTACCACCCCTCTTGC
ACATGCAAGATGGGCGAGGACGAGATGGCGGTTGTCGACTCAGAAACACGAGTTCATGGAATACAAGGGCTTAGAGTAGT
TGACTCCTCTATTTTTCCGACGATTCCAAATGGCAACCTGAATTCACCGACCATCATGTTAGCCGAGCGTGCCGCCGACT
TAATCTTAGGTAACACGCCACTCGCGCCAAGCACTGCAGAAGTGGTCATTAGCCAAGATTGGCAACAGCAGCAAAGGCAA
AGGCCACCAGCAAGATAA

Upstream 100 bases:

>100_bases
TGGCCGCGAAAACGGCAGCGAGACCCTAAAAGCTTACACCCAAATCAAAGCCGTATACGTGGGTATGCAGCCTCTTGAAA
GTCCATTTTAAGGAGCAGAC

Downstream 100 bases:

>100_bases
ATGCTTCGGCTTAGCTCATGCACAAACGCATTAGTGCACTAGTGCTGTACATGGGCTAAGCCAAGCCCCTCCACAAACGA
GGTGAAGATGTTCGGCATTC

Product: choline dehydrogenase

Products: NA

Alternate protein names: CDH; CHD [H]

Number of amino acids: Translated: 565; Mature: 564

Protein sequence:

>565_residues
MTITNPQYDYIIVGAGSAGCVLANRLSADSNNRVLLLETGGSDRSIFIQMPTALSIPMNTKKYAWQFETDAEPYLDNRRM
HCPRGKVLGGSSSINGMVYVRGHARDFDEWQEHGAKNWDYAHCLPYFKKAEDWAFGEDDYRGNDGPLGVNNGNEMKNPLY
KAFVAAGVDAGYLATDDYNGAQQEGFGPMHMTVKNGVRWSTANAYLRPAMQRENLTVITHAQVHRVLFSSKPGEANKVVG
VRFERKGKMREANASKEVILSAGSIGSPHILQLSGIGASDTLAKAGIEQVHELPGVGENLQDHLEFYFQFKCLKPISLNG
KLDPLNKLFIGTRWILNRSGLGATNHFESCGFIRSKAGLEWPDLQYHFLPAAMRYDGKEAFAGHGFQVHIGHNKPKSRGS
VKVVSNDPKVAPSILFNYLSHQDDIEGFRACVRLTREIINQPALDEYRGEEIQPGTAVQTDQQIDSFVRSTVESAYHPSC
TCKMGEDEMAVVDSETRVHGIQGLRVVDSSIFPTIPNGNLNSPTIMLAERAADLILGNTPLAPSTAEVVISQDWQQQQRQ
RPPAR

Sequences:

>Translated_565_residues
MTITNPQYDYIIVGAGSAGCVLANRLSADSNNRVLLLETGGSDRSIFIQMPTALSIPMNTKKYAWQFETDAEPYLDNRRM
HCPRGKVLGGSSSINGMVYVRGHARDFDEWQEHGAKNWDYAHCLPYFKKAEDWAFGEDDYRGNDGPLGVNNGNEMKNPLY
KAFVAAGVDAGYLATDDYNGAQQEGFGPMHMTVKNGVRWSTANAYLRPAMQRENLTVITHAQVHRVLFSSKPGEANKVVG
VRFERKGKMREANASKEVILSAGSIGSPHILQLSGIGASDTLAKAGIEQVHELPGVGENLQDHLEFYFQFKCLKPISLNG
KLDPLNKLFIGTRWILNRSGLGATNHFESCGFIRSKAGLEWPDLQYHFLPAAMRYDGKEAFAGHGFQVHIGHNKPKSRGS
VKVVSNDPKVAPSILFNYLSHQDDIEGFRACVRLTREIINQPALDEYRGEEIQPGTAVQTDQQIDSFVRSTVESAYHPSC
TCKMGEDEMAVVDSETRVHGIQGLRVVDSSIFPTIPNGNLNSPTIMLAERAADLILGNTPLAPSTAEVVISQDWQQQQRQ
RPPAR
>Mature_564_residues
TITNPQYDYIIVGAGSAGCVLANRLSADSNNRVLLLETGGSDRSIFIQMPTALSIPMNTKKYAWQFETDAEPYLDNRRMH
CPRGKVLGGSSSINGMVYVRGHARDFDEWQEHGAKNWDYAHCLPYFKKAEDWAFGEDDYRGNDGPLGVNNGNEMKNPLYK
AFVAAGVDAGYLATDDYNGAQQEGFGPMHMTVKNGVRWSTANAYLRPAMQRENLTVITHAQVHRVLFSSKPGEANKVVGV
RFERKGKMREANASKEVILSAGSIGSPHILQLSGIGASDTLAKAGIEQVHELPGVGENLQDHLEFYFQFKCLKPISLNGK
LDPLNKLFIGTRWILNRSGLGATNHFESCGFIRSKAGLEWPDLQYHFLPAAMRYDGKEAFAGHGFQVHIGHNKPKSRGSV
KVVSNDPKVAPSILFNYLSHQDDIEGFRACVRLTREIINQPALDEYRGEEIQPGTAVQTDQQIDSFVRSTVESAYHPSCT
CKMGEDEMAVVDSETRVHGIQGLRVVDSSIFPTIPNGNLNSPTIMLAERAADLILGNTPLAPSTAEVVISQDWQQQQRQR
PPAR

Specific function: Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine [H]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI217272839, Length=544, Percent_Identity=52.2058823529412, Blast_Score=555, Evalue=1e-158,
Organism=Escherichia coli, GI1786503, Length=551, Percent_Identity=54.0834845735027, Blast_Score=593, Evalue=1e-171,
Organism=Caenorhabditis elegans, GI17532301, Length=558, Percent_Identity=46.5949820788531, Blast_Score=488, Evalue=1e-138,
Organism=Drosophila melanogaster, GI24642048, Length=581, Percent_Identity=37.1772805507745, Blast_Score=335, Evalue=5e-92,
Organism=Drosophila melanogaster, GI45551458, Length=575, Percent_Identity=34.9565217391304, Blast_Score=316, Evalue=3e-86,
Organism=Drosophila melanogaster, GI45549471, Length=575, Percent_Identity=34.9565217391304, Blast_Score=315, Evalue=4e-86,
Organism=Drosophila melanogaster, GI24642042, Length=571, Percent_Identity=36.2521891418564, Blast_Score=304, Evalue=1e-82,
Organism=Drosophila melanogaster, GI24642055, Length=573, Percent_Identity=35.7766143106457, Blast_Score=303, Evalue=2e-82,
Organism=Drosophila melanogaster, GI24642059, Length=573, Percent_Identity=35.0785340314136, Blast_Score=291, Evalue=8e-79,
Organism=Drosophila melanogaster, GI17137792, Length=557, Percent_Identity=34.4703770197487, Blast_Score=289, Evalue=3e-78,
Organism=Drosophila melanogaster, GI24642039, Length=581, Percent_Identity=35.1118760757315, Blast_Score=277, Evalue=2e-74,
Organism=Drosophila melanogaster, GI24650267, Length=582, Percent_Identity=34.192439862543, Blast_Score=271, Evalue=9e-73,
Organism=Drosophila melanogaster, GI18859995, Length=569, Percent_Identity=32.688927943761, Blast_Score=261, Evalue=1e-69,
Organism=Drosophila melanogaster, GI18859993, Length=570, Percent_Identity=32.4561403508772, Blast_Score=249, Evalue=4e-66,
Organism=Drosophila melanogaster, GI24642035, Length=572, Percent_Identity=30.9440559440559, Blast_Score=245, Evalue=8e-65,
Organism=Drosophila melanogaster, GI24642037, Length=572, Percent_Identity=31.993006993007, Blast_Score=242, Evalue=4e-64,
Organism=Drosophila melanogaster, GI24642051, Length=571, Percent_Identity=30.122591943958, Blast_Score=241, Evalue=1e-63,
Organism=Drosophila melanogaster, GI24645930, Length=583, Percent_Identity=28.4734133790738, Blast_Score=169, Evalue=6e-42,
Organism=Drosophila melanogaster, GI24642057, Length=596, Percent_Identity=27.5167785234899, Blast_Score=143, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011533
- InterPro:   IPR012132
- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.1 [H]

Molecular weight: Translated: 62483; Mature: 62352

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS00623 GMC_OXRED_1 ; PS00624 GMC_OXRED_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTITNPQYDYIIVGAGSAGCVLANRLSADSNNRVLLLETGGSDRSIFIQMPTALSIPMNT
CCCCCCCCCEEEEECCCCCEEEEHCCCCCCCCCEEEEEECCCCCEEEEECCCEEECCCCC
KKYAWQFETDAEPYLDNRRMHCPRGKVLGGSSSINGMVYVRGHARDFDEWQEHGAKNWDY
CEEEEEECCCCCCCCCCCCCCCCCCCEECCCCCCCEEEEEECCCCCHHHHHHCCCCCCCH
AHCLPYFKKAEDWAFGEDDYRGNDGPLGVNNGNEMKNPLYKAFVAAGVDAGYLATDDYNG
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCC
AQQEGFGPMHMTVKNGVRWSTANAYLRPAMQRENLTVITHAQVHRVLFSSKPGEANKVVG
CHHCCCCCEEEEECCCCEEECCCHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCCCCCEEE
VRFERKGKMREANASKEVILSAGSIGSPHILQLSGIGASDTLAKAGIEQVHELPGVGENL
EEECCCCCCCCCCCCCEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCH
QDHLEFYFQFKCLKPISLNGKLDPLNKLFIGTRWILNRSGLGATNHFESCGFIRSKAGLE
HHHHHEEEEEEEECEEECCCCCCCCHHHHCCEEEEEECCCCCCCCCHHHCCCHHHCCCCC
WPDLQYHFLPAAMRYDGKEAFAGHGFQVHIGHNKPKSRGSVKVVSNDPKVAPSILFNYLS
CCCCEEEEECHHHHCCCCHHHCCCCEEEEECCCCCCCCCCEEEECCCCCCCHHHHHHHHC
HQDDIEGFRACVRLTREIINQPALDEYRGEEIQPGTAVQTDQQIDSFVRSTVESAYHPSC
CCCHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCE
TCKMGEDEMAVVDSETRVHGIQGLRVVDSSIFPTIPNGNLNSPTIMLAERAADLILGNTP
EEEECCCCEEEECCCCCEECCCCEEEECCCCCCCCCCCCCCCCEEEEEECCCHHEECCCC
LAPSTAEVVISQDWQQQQRQRPPAR
CCCCHHHEEECCHHHHHHHCCCCCC
>Mature Secondary Structure 
TITNPQYDYIIVGAGSAGCVLANRLSADSNNRVLLLETGGSDRSIFIQMPTALSIPMNT
CCCCCCCCEEEEECCCCCEEEEHCCCCCCCCCEEEEEECCCCCEEEEECCCEEECCCCC
KKYAWQFETDAEPYLDNRRMHCPRGKVLGGSSSINGMVYVRGHARDFDEWQEHGAKNWDY
CEEEEEECCCCCCCCCCCCCCCCCCCEECCCCCCCEEEEEECCCCCHHHHHHCCCCCCCH
AHCLPYFKKAEDWAFGEDDYRGNDGPLGVNNGNEMKNPLYKAFVAAGVDAGYLATDDYNG
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCC
AQQEGFGPMHMTVKNGVRWSTANAYLRPAMQRENLTVITHAQVHRVLFSSKPGEANKVVG
CHHCCCCCEEEEECCCCEEECCCHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCCCCCEEE
VRFERKGKMREANASKEVILSAGSIGSPHILQLSGIGASDTLAKAGIEQVHELPGVGENL
EEECCCCCCCCCCCCCEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCH
QDHLEFYFQFKCLKPISLNGKLDPLNKLFIGTRWILNRSGLGATNHFESCGFIRSKAGLE
HHHHHEEEEEEEECEEECCCCCCCCHHHHCCEEEEEECCCCCCCCCHHHCCCHHHCCCCC
WPDLQYHFLPAAMRYDGKEAFAGHGFQVHIGHNKPKSRGSVKVVSNDPKVAPSILFNYLS
CCCCEEEEECHHHHCCCCHHHCCCCEEEEECCCCCCCCCCEEEECCCCCCCHHHHHHHHC
HQDDIEGFRACVRLTREIINQPALDEYRGEEIQPGTAVQTDQQIDSFVRSTVESAYHPSC
CCCHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCE
TCKMGEDEMAVVDSETRVHGIQGLRVVDSSIFPTIPNGNLNSPTIMLAERAADLILGNTP
EEEECCCCEEEECCCCCEECCCCEEEECCCCCCCCCCCCCCCCEEEEEECCCHHEECCCC
LAPSTAEVVISQDWQQQQRQRPPAR
CCCCHHHEEECCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA