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The map label for this gene is erpA

Identifier: 167622970

GI number: 167622970

Start: 1265203

End: 1265553

Strand: Direct

Name: erpA

Synonym: Shal_1036

Alternate gene names: 167622970

Gene position: 1265203-1265553 (Clockwise)

Preceding gene: 167622969

Following gene: 167622976

Centisome position: 24.21

GC content: 45.58

Gene sequence:

>351_bases
ATGACTGAACAAGCTGAAGATGCTTTGCCAATCCGCTTTACCGATGCGGCGGCTTCAAAAGTAAAAACCCTGCTCGAAGA
GGAAGAAAATGACGCACTTAAGTTACGAGTCTATGTAACGGGTGGCGGATGCTCAGGTTTCCAGTATGGCTTTACCTTCG
ATGAGAAGATAAACGAAGGAGACTATACTGTAGAGAAGCAAGGTGTTCAGTTAGTTGTTGACCCTATGAGCCTACAATAT
CTTGTTGGTGGCGAAGTGGATTATACTTCAGGCCTTGAAGGTTCACGCTTCTTCGTTAAAAATCCCAACGCGACCACCAC
ATGTGGTTGTGGTGCAAGCTTCTCCGTTTAA

Upstream 100 bases:

>100_bases
CAAGATTTACTTGTGGATGAAAAAGAGCAGGGCATATTACTTGAACAAAACACTCAGGTATTAGATAATTCTGCACAGCA
AACAGAAGTAAGAGGTAGTA

Downstream 100 bases:

>100_bases
CCTTTCGATAAGGCAAACTGAGCAAGTAAAAAAAGCCGTCAAATGACGGCTTTTTTTATAACTGCAGACTCAACAAAACA
GATCAGCGCATAATATTGAG

Product: iron-sulfur cluster insertion protein ErpA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 116; Mature: 115

Protein sequence:

>116_residues
MTEQAEDALPIRFTDAAASKVKTLLEEEENDALKLRVYVTGGGCSGFQYGFTFDEKINEGDYTVEKQGVQLVVDPMSLQY
LVGGEVDYTSGLEGSRFFVKNPNATTTCGCGASFSV

Sequences:

>Translated_116_residues
MTEQAEDALPIRFTDAAASKVKTLLEEEENDALKLRVYVTGGGCSGFQYGFTFDEKINEGDYTVEKQGVQLVVDPMSLQY
LVGGEVDYTSGLEGSRFFVKNPNATTTCGCGASFSV
>Mature_115_residues
TEQAEDALPIRFTDAAASKVKTLLEEEENDALKLRVYVTGGGCSGFQYGFTFDEKINEGDYTVEKQGVQLVVDPMSLQYL
VGGEVDYTSGLEGSRFFVKNPNATTTCGCGASFSV

Specific function: Required for insertion of 4Fe-4S clusters for at least ispG

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family

Homologues:

Organism=Homo sapiens, GI160420328, Length=107, Percent_Identity=46.7289719626168, Blast_Score=85, Evalue=1e-17,
Organism=Homo sapiens, GI52426768, Length=106, Percent_Identity=31.1320754716981, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1786351, Length=109, Percent_Identity=77.0642201834862, Blast_Score=184, Evalue=1e-48,
Organism=Escherichia coli, GI1788877, Length=110, Percent_Identity=40, Blast_Score=69, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71998452, Length=121, Percent_Identity=40.495867768595, Blast_Score=85, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI25146411, Length=106, Percent_Identity=34.9056603773585, Blast_Score=78, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI193209025, Length=106, Percent_Identity=34.9056603773585, Blast_Score=78, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323001, Length=106, Percent_Identity=34.9056603773585, Blast_Score=72, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24649697, Length=83, Percent_Identity=48.1927710843374, Blast_Score=78, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24642263, Length=112, Percent_Identity=34.8214285714286, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ERPA_SHEHH (B0TIR0)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001673264.1
- ProteinModelPortal:   B0TIR0
- SMR:   B0TIR0
- GeneID:   5906979
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_1036
- HOGENOM:   HBG730174
- OMA:   TFDDQIN
- ProtClustDB:   PRK13623
- BioCyc:   SHAL458817:SHAL_1036-MONOMER
- HAMAP:   MF_01380
- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063
- Gene3D:   G3DSA:2.60.300.12
- PANTHER:   PTHR10072
- TIGRFAMs:   TIGR00049

Pfam domain/function: PF01521 Fe-S_biosyn; SSF89360 HesB_yadR_yfhF-like

EC number: NA

Molecular weight: Translated: 12554; Mature: 12423

Theoretical pI: Translated: 4.05; Mature: 4.05

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEQAEDALPIRFTDAAASKVKTLLEEEENDALKLRVYVTGGGCSGFQYGFTFDEKINEG
CCCCCCCCCCEEECCHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCEEECCCCCCC
DYTVEKQGVQLVVDPMSLQYLVGGEVDYTSGLEGSRFFVKNPNATTTCGCGASFSV
CEEEECCCEEEEECCCEEEEEECCCEECCCCCCCCEEEEECCCCCEEECCCCCCCC
>Mature Secondary Structure 
TEQAEDALPIRFTDAAASKVKTLLEEEENDALKLRVYVTGGGCSGFQYGFTFDEKINEG
CCCCCCCCCEEECCHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCEEECCCCCCC
DYTVEKQGVQLVVDPMSLQYLVGGEVDYTSGLEGSRFFVKNPNATTTCGCGASFSV
CEEEECCCEEEEECCCEEEEEECCCEECCCCCCCCEEEEECCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA