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The map label for this gene is gcp

Identifier: 167622947

GI number: 167622947

Start: 1239425

End: 1240441

Strand: Direct

Name: gcp

Synonym: Shal_1008

Alternate gene names: 167622947

Gene position: 1239425-1240441 (Clockwise)

Preceding gene: 167622941

Following gene: 167622950

Centisome position: 23.71

GC content: 49.95

Gene sequence:

>1017_bases
ATGCGGGTTCTAGGTATTGAAACATCCTGTGATGAAACAGGGATTGCGGTTTATGATGATGAAAAAGGCTTGCTGTCGCA
TGCGCTTTACAGTCAGGTTAAATTGCATGCCGACTATGGTGGGGTAGTGCCAGAGTTGGCTTCTCGCGACCATGTCCGCA
AAATTGTACCTTTAATACGCCAAGCGTTAGCGGATGCTGACATGACTATCGAGGATCTCGATGGTATTGCCTATACCAAA
GGACCTGGTCTTATTGGCGCGCTACTAGTCGGTGCTTGTGTCGGTCGCGCATTGGCTTTTTCATGGGATAAGCCTGCTAT
TGGTGTACACCACATGGAAGGGCATTTATTGGCGCCGATGCTTGAAGATGATGTACCAGAGTTTCCGTTTCTTGCGCTAT
TGGTTTCTGGTGGTCACTCAATGCTTGTGGGTGTTGAAGGGATTGGTCGCTATACCGTACTTGGAGAGTCAGTTGATGAC
GCAGCGGGTGAAGCGTTCGATAAGACCGCTAAGCTGATGGGGCTCGATTATCCAGGTGGCCCAAGGCTATCTAAGTTGGC
TGCCAAAGGTGTGCCAAACAGTTACCGTTTTCCGCGCCCAATGACTGATAAACCTGGACTTAACATGAGTTTCTCAGGCC
TTAAAACCTTTGCGGCGAACACCATTGCGGCAGAGCCTAAAGACGAGCAAACTCGCGCCAATATCGCCTGTGCCTTTGAA
GAGGCGGTGGTCGATACCTTAGGGATCAAGTGTAAGCGTGCATTGAAGCAAACAGGTTATAAAAACTTAGTGATAGCGGG
CGGCGTAAGCGCCAATACCCGCTTACGCGCATCGTTAAGCGAAATGATGCAAGGCCTTGGCGGAAAAGTGTATTACCCTC
GGGGCGAATTTTGTACCGATAACGGCGCGATGATCGCCTATGCGGGCTTACAGCGCTTAAAAGCCGGACAAGTTGAAGAT
TTGGCGGTAAAAGGGCAGCCAAGATGGCCGCTCGATACCTTAGAGCCTGTAGATTAA

Upstream 100 bases:

>100_bases
TATTAGGCGATATTATCCGCAGACCGCGATAGGACTATGGAGTAATTAAAGCACAGCAGGTAGAATTAGCGGTAATTATG
TCAACCGAAGACGAGAAATA

Downstream 100 bases:

>100_bases
GATTTAAAGGTAACTAGAAAAACGGCGCTCATAGAGCGCCGTTTTTGTTGATACCGTTTCGATTATCAGAATCCGTGATT
GGCGTTACTGACACGGAACC

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MRVLGIETSCDETGIAVYDDEKGLLSHALYSQVKLHADYGGVVPELASRDHVRKIVPLIRQALADADMTIEDLDGIAYTK
GPGLIGALLVGACVGRALAFSWDKPAIGVHHMEGHLLAPMLEDDVPEFPFLALLVSGGHSMLVGVEGIGRYTVLGESVDD
AAGEAFDKTAKLMGLDYPGGPRLSKLAAKGVPNSYRFPRPMTDKPGLNMSFSGLKTFAANTIAAEPKDEQTRANIACAFE
EAVVDTLGIKCKRALKQTGYKNLVIAGGVSANTRLRASLSEMMQGLGGKVYYPRGEFCTDNGAMIAYAGLQRLKAGQVED
LAVKGQPRWPLDTLEPVD

Sequences:

>Translated_338_residues
MRVLGIETSCDETGIAVYDDEKGLLSHALYSQVKLHADYGGVVPELASRDHVRKIVPLIRQALADADMTIEDLDGIAYTK
GPGLIGALLVGACVGRALAFSWDKPAIGVHHMEGHLLAPMLEDDVPEFPFLALLVSGGHSMLVGVEGIGRYTVLGESVDD
AAGEAFDKTAKLMGLDYPGGPRLSKLAAKGVPNSYRFPRPMTDKPGLNMSFSGLKTFAANTIAAEPKDEQTRANIACAFE
EAVVDTLGIKCKRALKQTGYKNLVIAGGVSANTRLRASLSEMMQGLGGKVYYPRGEFCTDNGAMIAYAGLQRLKAGQVED
LAVKGQPRWPLDTLEPVD
>Mature_338_residues
MRVLGIETSCDETGIAVYDDEKGLLSHALYSQVKLHADYGGVVPELASRDHVRKIVPLIRQALADADMTIEDLDGIAYTK
GPGLIGALLVGACVGRALAFSWDKPAIGVHHMEGHLLAPMLEDDVPEFPFLALLVSGGHSMLVGVEGIGRYTVLGESVDD
AAGEAFDKTAKLMGLDYPGGPRLSKLAAKGVPNSYRFPRPMTDKPGLNMSFSGLKTFAANTIAAEPKDEQTRANIACAFE
EAVVDTLGIKCKRALKQTGYKNLVIAGGVSANTRLRASLSEMMQGLGGKVYYPRGEFCTDNGAMIAYAGLQRLKAGQVED
LAVKGQPRWPLDTLEPVD

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=355, Percent_Identity=33.8028169014084, Blast_Score=180, Evalue=1e-45,
Organism=Homo sapiens, GI8923380, Length=339, Percent_Identity=32.4483775811209, Blast_Score=146, Evalue=3e-35,
Organism=Escherichia coli, GI1789445, Length=334, Percent_Identity=73.9520958083832, Blast_Score=510, Evalue=1e-146,
Organism=Caenorhabditis elegans, GI17557464, Length=328, Percent_Identity=32.6219512195122, Blast_Score=162, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI71995670, Length=330, Percent_Identity=33.030303030303, Blast_Score=134, Evalue=7e-32,
Organism=Saccharomyces cerevisiae, GI6320099, Length=368, Percent_Identity=33.1521739130435, Blast_Score=174, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6322891, Length=350, Percent_Identity=28, Blast_Score=116, Evalue=4e-27,
Organism=Drosophila melanogaster, GI20129063, Length=340, Percent_Identity=34.7058823529412, Blast_Score=188, Evalue=6e-48,
Organism=Drosophila melanogaster, GI21357207, Length=327, Percent_Identity=30.5810397553517, Blast_Score=145, Evalue=4e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_SHEHH (B0TIN7)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001673241.1
- ProteinModelPortal:   B0TIN7
- SMR:   B0TIN7
- MEROPS:   M22.001
- GeneID:   5905392
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_1008
- HOGENOM:   HBG304663
- OMA:   PAVGVHH
- ProtClustDB:   PRK09604
- BioCyc:   SHAL458817:SHAL_1008-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 36090; Mature: 36090

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLGIETSCDETGIAVYDDEKGLLSHALYSQVKLHADYGGVVPELASRDHVRKIVPLIR
CEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHEEECCCCCCCHHHHCHHHHHHHHHHHH
QALADADMTIEDLDGIAYTKGPGLIGALLVGACVGRALAFSWDKPAIGVHHMEGHLLAPM
HHHHCCCCCHHHCCCEEEECCCCHHHHHHHHHHHHHHHEECCCCCCCCEEECCCCEECCH
LEDDVPEFPFLALLVSGGHSMLVGVEGIGRYTVLGESVDDAAGEAFDKTAKLMGLDYPGG
HHCCCCCCCHHHHHHCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCC
PRLSKLAAKGVPNSYRFPRPMTDKPGLNMSFSGLKTFAANTIAAEPKDEQTRANIACAFE
CCHHHHHHCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCCCCHHHHHEEEHHH
EAVVDTLGIKCKRALKQTGYKNLVIAGGVSANTRLRASLSEMMQGLGGKVYYPRGEFCTD
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCEEEECCCCEECC
NGAMIAYAGLQRLKAGQVEDLAVKGQPRWPLDTLEPVD
CCCEEEEHHHHHHCCCCCCEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MRVLGIETSCDETGIAVYDDEKGLLSHALYSQVKLHADYGGVVPELASRDHVRKIVPLIR
CEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHEEECCCCCCCHHHHCHHHHHHHHHHHH
QALADADMTIEDLDGIAYTKGPGLIGALLVGACVGRALAFSWDKPAIGVHHMEGHLLAPM
HHHHCCCCCHHHCCCEEEECCCCHHHHHHHHHHHHHHHEECCCCCCCCEEECCCCEECCH
LEDDVPEFPFLALLVSGGHSMLVGVEGIGRYTVLGESVDDAAGEAFDKTAKLMGLDYPGG
HHCCCCCCCHHHHHHCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCC
PRLSKLAAKGVPNSYRFPRPMTDKPGLNMSFSGLKTFAANTIAAEPKDEQTRANIACAFE
CCHHHHHHCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCCCCHHHHHEEEHHH
EAVVDTLGIKCKRALKQTGYKNLVIAGGVSANTRLRASLSEMMQGLGGKVYYPRGEFCTD
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCEEEECCCCEECC
NGAMIAYAGLQRLKAGQVEDLAVKGQPRWPLDTLEPVD
CCCEEEEHHHHHHCCCCCCEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA