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The map label for this gene is hlyB [H]

Identifier: 167622892

GI number: 167622892

Start: 1171157

End: 1172878

Strand: Direct

Name: hlyB [H]

Synonym: Shal_0952

Alternate gene names: 167622892

Gene position: 1171157-1172878 (Clockwise)

Preceding gene: 167622890

Following gene: 167622895

Centisome position: 22.41

GC content: 47.15

Gene sequence:

>1722_bases
ATGTCTGTATTAATCGAACAGTTAGGGCAAGATGAGGTTCGCCAATCTCATCAATCACAGTCCGGCTTTATCTCGCTTTT
TAAATCGGTACGATTTCAACTTAAATTCATCGTATTTCTGACCGTAATATCATTTTTATTCTTAGGCTATAAAGGCATTA
CCGGTATGCAAGATGCCGGGGAGTCGATAGGCGAGCTGCATGCCCAAGGTATGCAGCATAGTATTCGTGCGGGTAAGGTA
CTTAATGAACTCGCAATTGCACGTAGCGAACTGTTATTGGCATTTCAGCATGACCCAAGTAGTCAATTTTCTGAAATGCA
TAATCACCCACTGACGTTACATATTTCGCAGGCTCAAGCGGCAATCGCCCAGCTGCATAACATCATAGATAATGAGATCT
TAGGAGCAAACTTAGATAATGAAGAGCGCCTGCAAGTTAACCGTTTAAAGAGCCTGCTCGACAAGGTGGTTGCTCTGGGA
TTCACGCCAACCATCGATGCCTTACAGCGAGGCGAATATGAAGCGGCAAACCGAGTATTACTGACCCAGATTAACCCGCT
TTTTAAGAGCATTACTGCCGAAGCGCAATCATTCTTAGATCTGCAGGTTGCAGGCGGTGAAGAGACTTATATAGGGTTTA
ATCAAGATATGCGAGTGTATATCTTGCTGGTAGCGATCTTCTCGAGTGTTTGTATGCTGGTGATCAGCATTAGCTCATCG
TTAATCGTTCGCCGTATGGGTAAGGCGATGACAGAGATTGAGATGACGGCCAACGATATTGCCAATGGCGATCTGACAAA
ACGCATCGTGATTAGTGGTGATGATGAGTTTACTCATATCGCTGATTACGTTAATCGGATAGCAGCAAGATTTCAGCATG
CGGTGCAAAACACCCATGAATCGACCTCACGTTTAGCCAGTGCGGCCGAAGAGAACTCAGTGGTATCGACGCAGACTCAA
CGTAATGTGGTTGAGCAGCAACAGCAAACTCAGCAGATCGCCGCTGCGATTCATCAGTTTACTGCGACTGTGAGAGAGGT
GGCGCAAAGCGCAGAAGCAGCAGCAAGTTCGTCGTTAGAGGCTAACGATGCGGCGCATCACGGTCAGGCTGTTGTCGATG
AGAGTATCTCGGTGATTGAGACTCTATCTACCGAGATGGATGGTGCGACAGAAGCGATGCAGTTATTGTCTAAGTCTTCC
GATGAGATTGGCTCAGTCGTTGATGTTATTCAGGGGATCTCGCAGCAAACTAACTTACTTGCCTTAAATGCGGCAATTGA
AGCTGCGCGTGCTGGTGAGCAGGGTAGAGGTTTTGCCGTAGTGGCCGATGAGGTTCGCTCGCTTGCCAAACGCACCCAAG
ACTCGACAGAGGAAATTCAACAAATGATCCAACGTCTACAGCAAGGTGCACGTGACTCAATGTTGATGATGGAGCGCGGT
ACAGAGCAAGCTAAATTAAGCGTGGAGAAATCGGCGCAAGCTGGCGCTGCTTTATTGCAAATTATGACCAGCATCGAACA
GATCAATGCGTTGAATACTCAGATAGCGACGGCGTCAGAAGAGCAGAGCTTAGTCACGGAAGAGATCAATCGTAATATCA
TCAATATTAGCGATATTTCGGATCAAACCGCTGCAGGTGCTGAGCAAACACAAGCCGCCACCCATGAGTTAGCTCAGCTT
GCTGAAAGTATGCAGCAAGAGATCGCCTACTACCGAGTGTGA

Upstream 100 bases:

>100_bases
CTATGCTGCAGCAGCAGCGTTTTACCTGTGGTAGGACGAGTGCGTTAGAGTGCTTTTGTTTTCATGATTCCATCAATACT
GGTGGGGAACAGGAATTAAT

Downstream 100 bases:

>100_bases
TTTTAGTGCTTATACCTATGCCTAGAGCCTAGAGGCTAGAGGCTAGAGGCTAGAGGCTGAAATTGAGATAACAAAAAGGG
CTGTCGATGACAGCCCTTTT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 573; Mature: 572

Protein sequence:

>573_residues
MSVLIEQLGQDEVRQSHQSQSGFISLFKSVRFQLKFIVFLTVISFLFLGYKGITGMQDAGESIGELHAQGMQHSIRAGKV
LNELAIARSELLLAFQHDPSSQFSEMHNHPLTLHISQAQAAIAQLHNIIDNEILGANLDNEERLQVNRLKSLLDKVVALG
FTPTIDALQRGEYEAANRVLLTQINPLFKSITAEAQSFLDLQVAGGEETYIGFNQDMRVYILLVAIFSSVCMLVISISSS
LIVRRMGKAMTEIEMTANDIANGDLTKRIVISGDDEFTHIADYVNRIAARFQHAVQNTHESTSRLASAAEENSVVSTQTQ
RNVVEQQQQTQQIAAAIHQFTATVREVAQSAEAAASSSLEANDAAHHGQAVVDESISVIETLSTEMDGATEAMQLLSKSS
DEIGSVVDVIQGISQQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAKRTQDSTEEIQQMIQRLQQGARDSMLMMERG
TEQAKLSVEKSAQAGAALLQIMTSIEQINALNTQIATASEEQSLVTEEINRNIINISDISDQTAAGAEQTQAATHELAQL
AESMQQEIAYYRV

Sequences:

>Translated_573_residues
MSVLIEQLGQDEVRQSHQSQSGFISLFKSVRFQLKFIVFLTVISFLFLGYKGITGMQDAGESIGELHAQGMQHSIRAGKV
LNELAIARSELLLAFQHDPSSQFSEMHNHPLTLHISQAQAAIAQLHNIIDNEILGANLDNEERLQVNRLKSLLDKVVALG
FTPTIDALQRGEYEAANRVLLTQINPLFKSITAEAQSFLDLQVAGGEETYIGFNQDMRVYILLVAIFSSVCMLVISISSS
LIVRRMGKAMTEIEMTANDIANGDLTKRIVISGDDEFTHIADYVNRIAARFQHAVQNTHESTSRLASAAEENSVVSTQTQ
RNVVEQQQQTQQIAAAIHQFTATVREVAQSAEAAASSSLEANDAAHHGQAVVDESISVIETLSTEMDGATEAMQLLSKSS
DEIGSVVDVIQGISQQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAKRTQDSTEEIQQMIQRLQQGARDSMLMMERG
TEQAKLSVEKSAQAGAALLQIMTSIEQINALNTQIATASEEQSLVTEEINRNIINISDISDQTAAGAEQTQAATHELAQL
AESMQQEIAYYRV
>Mature_572_residues
SVLIEQLGQDEVRQSHQSQSGFISLFKSVRFQLKFIVFLTVISFLFLGYKGITGMQDAGESIGELHAQGMQHSIRAGKVL
NELAIARSELLLAFQHDPSSQFSEMHNHPLTLHISQAQAAIAQLHNIIDNEILGANLDNEERLQVNRLKSLLDKVVALGF
TPTIDALQRGEYEAANRVLLTQINPLFKSITAEAQSFLDLQVAGGEETYIGFNQDMRVYILLVAIFSSVCMLVISISSSL
IVRRMGKAMTEIEMTANDIANGDLTKRIVISGDDEFTHIADYVNRIAARFQHAVQNTHESTSRLASAAEENSVVSTQTQR
NVVEQQQQTQQIAAAIHQFTATVREVAQSAEAAASSSLEANDAAHHGQAVVDESISVIETLSTEMDGATEAMQLLSKSSD
EIGSVVDVIQGISQQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAKRTQDSTEEIQQMIQRLQQGARDSMLMMERGT
EQAKLSVEKSAQAGAALLQIMTSIEQINALNTQIATASEEQSLVTEEINRNIINISDISDQTAAGAEQTQAATHELAQLA
ESMQQEIAYYRV

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=316, Percent_Identity=31.3291139240506, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI1788194, Length=368, Percent_Identity=31.25, Blast_Score=132, Evalue=7e-32,
Organism=Escherichia coli, GI1788195, Length=287, Percent_Identity=32.0557491289199, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1787690, Length=557, Percent_Identity=25.3141831238779, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1789453, Length=254, Percent_Identity=28.3464566929134, Blast_Score=93, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 62539; Mature: 62408

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLIEQLGQDEVRQSHQSQSGFISLFKSVRFQLKFIVFLTVISFLFLGYKGITGMQDAG
CCCHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
ESIGELHAQGMQHSIRAGKVLNELAIARSELLLAFQHDPSSQFSEMHNHPLTLHISQAQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHCCCCEEEEEHHHHH
AIAQLHNIIDNEILGANLDNEERLQVNRLKSLLDKVVALGFTPTIDALQRGEYEAANRVL
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHCCCH
LTQINPLFKSITAEAQSFLDLQVAGGEETYIGFNQDMRVYILLVAIFSSVCMLVISISSS
HHHHHHHHHHHHHHHHHHHEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
LIVRRMGKAMTEIEMTANDIANGDLTKRIVISGDDEFTHIADYVNRIAARFQHAVQNTHE
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
STSRLASAAEENSVVSTQTQRNVVEQQQQTQQIAAAIHQFTATVREVAQSAEAAASSSLE
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ANDAAHHGQAVVDESISVIETLSTEMDGATEAMQLLSKSSDEIGSVVDVIQGISQQTNLL
CCCHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCEE
ALNAAIEAARAGEQGRGFAVVADEVRSLAKRTQDSTEEIQQMIQRLQQGARDSMLMMERG
HHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHCC
TEQAKLSVEKSAQAGAALLQIMTSIEQINALNTQIATASEEQSLVTEEINRNIINISDIS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEECCCC
DQTAAGAEQTQAATHELAQLAESMQQEIAYYRV
CHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SVLIEQLGQDEVRQSHQSQSGFISLFKSVRFQLKFIVFLTVISFLFLGYKGITGMQDAG
CCHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
ESIGELHAQGMQHSIRAGKVLNELAIARSELLLAFQHDPSSQFSEMHNHPLTLHISQAQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHCCCCEEEEEHHHHH
AIAQLHNIIDNEILGANLDNEERLQVNRLKSLLDKVVALGFTPTIDALQRGEYEAANRVL
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHCCCH
LTQINPLFKSITAEAQSFLDLQVAGGEETYIGFNQDMRVYILLVAIFSSVCMLVISISSS
HHHHHHHHHHHHHHHHHHHEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
LIVRRMGKAMTEIEMTANDIANGDLTKRIVISGDDEFTHIADYVNRIAARFQHAVQNTHE
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
STSRLASAAEENSVVSTQTQRNVVEQQQQTQQIAAAIHQFTATVREVAQSAEAAASSSLE
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ANDAAHHGQAVVDESISVIETLSTEMDGATEAMQLLSKSSDEIGSVVDVIQGISQQTNLL
CCCHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCEE
ALNAAIEAARAGEQGRGFAVVADEVRSLAKRTQDSTEEIQQMIQRLQQGARDSMLMMERG
HHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHCC
TEQAKLSVEKSAQAGAALLQIMTSIEQINALNTQIATASEEQSLVTEEINRNIINISDIS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEECCCC
DQTAAGAEQTQAATHELAQLAESMQQEIAYYRV
CHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]