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The map label for this gene is rpiA [H]

Identifier: 167622810

GI number: 167622810

Start: 1086324

End: 1086986

Strand: Reverse

Name: rpiA [H]

Synonym: Shal_0870

Alternate gene names: 167622810

Gene position: 1086986-1086324 (Counterclockwise)

Preceding gene: 167622813

Following gene: 167622808

Centisome position: 20.8

GC content: 46.61

Gene sequence:

>663_bases
ATGATGACTCAAGATGAAATGAAAAAAGCTGCCGGATGGGCTGCTCTTCAGTACGTAGAAGAAAACAGCATTGTTGGCGT
AGGTACAGGCTCAACGGTAAATCACTTTATTGATGCACTTGCTACAATGAAGTTCGATATCGAAGGTGCGGTATCGAGCT
CTGAAGCATCAACAGAAAAAATGAAGGCCCTAGGTATTCCTGTTTTTGACCTAAACAGCGTCGACGAGCTATCTGTCTAT
GTTGATGGCGCCGATGAGATCAACGGCCATATGGACATGATCAAAGGCGGCGGTGCAGCACTGACTCGCGAAAAGATCGT
TGCAGCCGTTGCCGAAAAGTTTATCTGTATCGTTGATAACACTAAGCAGGTTGATATTTTAGGCGATTTCCCACTGCCTA
TCGAAGTGATCCCAATGGCACGTTCGTACGTGGCTCGCCAGATTGTTAAGCTTGGCGGCGACCCTGTTTACCGTGAAGGT
TGTGTAACCGATAACGGCAACATCATCTTAGATGTGTACAACATGAAGATCATGAATCCGAAAGCGTTAGAAGAGCAGAT
CAACGGTATCGTGGGTGTGGTAACTAACGGCCTGTTCGCCATGCGCGGCGCAGACGTGTTGTTAGTTGGTACTCCTGACG
GCGTTAAAACAATTACTTATTAA

Upstream 100 bases:

>100_bases
CTTTTAAAGCAAAATTCAGCCGCGCTCACCACGTTAAACGAGTATACTGACGGCAATATTTTTAACCTTGTCTTTAACAT
TATCTTTAATAAAGGATTTC

Downstream 100 bases:

>100_bases
TTGTTTTTTGAGCCTTACTGTTCGGTGGGAAGCTTTCCACCATCGCTAAAGCCACTCGTTTGAGTGGCTTTATTGTTTTT
TGCATCAAATTTTATTTAGG

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MMTQDEMKKAAGWAALQYVEENSIVGVGTGSTVNHFIDALATMKFDIEGAVSSSEASTEKMKALGIPVFDLNSVDELSVY
VDGADEINGHMDMIKGGGAALTREKIVAAVAEKFICIVDNTKQVDILGDFPLPIEVIPMARSYVARQIVKLGGDPVYREG
CVTDNGNIILDVYNMKIMNPKALEEQINGIVGVVTNGLFAMRGADVLLVGTPDGVKTITY

Sequences:

>Translated_220_residues
MMTQDEMKKAAGWAALQYVEENSIVGVGTGSTVNHFIDALATMKFDIEGAVSSSEASTEKMKALGIPVFDLNSVDELSVY
VDGADEINGHMDMIKGGGAALTREKIVAAVAEKFICIVDNTKQVDILGDFPLPIEVIPMARSYVARQIVKLGGDPVYREG
CVTDNGNIILDVYNMKIMNPKALEEQINGIVGVVTNGLFAMRGADVLLVGTPDGVKTITY
>Mature_220_residues
MMTQDEMKKAAGWAALQYVEENSIVGVGTGSTVNHFIDALATMKFDIEGAVSSSEASTEKMKALGIPVFDLNSVDELSVY
VDGADEINGHMDMIKGGGAALTREKIVAAVAEKFICIVDNTKQVDILGDFPLPIEVIPMARSYVARQIVKLGGDPVYREG
CVTDNGNIILDVYNMKIMNPKALEEQINGIVGVVTNGLFAMRGADVLLVGTPDGVKTITY

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=229, Percent_Identity=36.6812227074236, Blast_Score=112, Evalue=2e-25,
Organism=Escherichia coli, GI1789280, Length=217, Percent_Identity=77.4193548387097, Blast_Score=344, Evalue=3e-96,
Organism=Caenorhabditis elegans, GI17551758, Length=210, Percent_Identity=37.1428571428571, Blast_Score=109, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6324669, Length=246, Percent_Identity=29.2682926829268, Blast_Score=80, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281364072, Length=204, Percent_Identity=35.7843137254902, Blast_Score=88, Evalue=6e-18,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 23548; Mature: 23548

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTQDEMKKAAGWAALQYVEENSIVGVGTGSTVNHFIDALATMKFDIEGAVSSSEASTEK
CCCHHHHHHHHHHHHEEEECCCCEEEECCCCHHHHHHHHHHHEEEEECCCCCCCCHHHHH
MKALGIPVFDLNSVDELSVYVDGADEINGHMDMIKGGGAALTREKIVAAVAEKFICIVDN
HHHHCCCEECCCCCCEEEEEECCHHHCCCCEEEEECCCCHHHHHHHHHHHHHCEEEEECC
TKQVDILGDFPLPIEVIPMARSYVARQIVKLGGDPVYREGCVTDNGNIILDVYNMKIMNP
CEEEEEEECCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCEECCCCEEEEEECEEECCH
KALEEQINGIVGVVTNGLFAMRGADVLLVGTPDGVKTITY
HHHHHHHCCEEEEHHCCEEEECCCCEEEEECCCCCEEECC
>Mature Secondary Structure
MMTQDEMKKAAGWAALQYVEENSIVGVGTGSTVNHFIDALATMKFDIEGAVSSSEASTEK
CCCHHHHHHHHHHHHEEEECCCCEEEECCCCHHHHHHHHHHHEEEEECCCCCCCCHHHHH
MKALGIPVFDLNSVDELSVYVDGADEINGHMDMIKGGGAALTREKIVAAVAEKFICIVDN
HHHHCCCEECCCCCCEEEEEECCHHHCCCCEEEEECCCCHHHHHHHHHHHHHCEEEEECC
TKQVDILGDFPLPIEVIPMARSYVARQIVKLGGDPVYREGCVTDNGNIILDVYNMKIMNP
CEEEEEEECCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCEECCCCEEEEEECEEECCH
KALEEQINGIVGVVTNGLFAMRGADVLLVGTPDGVKTITY
HHHHHHHCCEEEEHHCCEEEECCCCEEEEECCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA