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The map label for this gene is dsbC [H]

Identifier: 167622801

GI number: 167622801

Start: 1073700

End: 1074428

Strand: Direct

Name: dsbC [H]

Synonym: Shal_0861

Alternate gene names: 167622801

Gene position: 1073700-1074428 (Clockwise)

Preceding gene: 167622800

Following gene: 167622802

Centisome position: 20.54

GC content: 45.68

Gene sequence:

>729_bases
ATGAAGTTCACTCGAACATTTTCTCTGATTGCTGCAATGATGATTGCACCAGCAGCTTTCGCAGCGTCAAGCAGTACAGG
CGACGATACTGAAGCGTTAAAGCAAAAACTAAGTGACGCGCTAAGCGTTGAAGTGATCTCTATTAAGCCGTCACCTATTT
CAGAGCTTTATGAAGCCTTTACTGATCGTGGTGTGCTTTACATTACTAAAGATGGTTCAAAACTGTTTCACGGTAATCTT
TATGATCTTGATAAGGGCATGAAGAACCTAACCGAAGCCGCAATGTCAGGCCCTCGTGTGGATATGATGAAGCCACTTGA
AGACAGCATGTTGGTTTACAAAGCCAAAAACGAAAAGCATGTCGTGACCATTTTTACCGATGTCAGCTGCGGATATTGCC
GTAAGTTACATAACGAGATGCAAGAGTACAACGACCTAGGGATTACCGTGCGTTACCTAGCGTTCCCACGTGCAGGGGTT
CCATCTGCCAATGCCGATGAGATGGAGTCAGTATGGTGCGCCGCCGACCCATTAAAAGCCATGGGCGCAGCTAAAAATGG
CAAAGCGGTTAAACAAGCTTCATGTGATGCAAAAATCAAAGAGCAGTATGAGTTAGGCCAAGCATTTGGTATTAACGGTA
CGCCAGCGATTATTCTTGAAGACGGTACCCTCATTCCTGGTTACCAGCCTCCTAAGGCACTGCTACGTACTTTAGAGTCG
GTACAGTAA

Upstream 100 bases:

>100_bases
AATTTGCTTTAAATAGCGTGAGTCTGTAACTTTTCAGCTCCAGATAAGGTCTAATTAATTATATCCATAAGTCTGCCCCT
TACAAAGAGTAGGAAAACTA

Downstream 100 bases:

>100_bases
TTCAGTCTTTGAATTCAGCCCGGAATTGAGTCTGAGAAGCAAAAAGGTGAGCCTAGGCTCACCTTTTTTGTGCCCCTTTG
CCAGCAGTCTTTGCTATGCT

Product: thiol:disulfide interchange protein DsbC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MKFTRTFSLIAAMMIAPAAFAASSSTGDDTEALKQKLSDALSVEVISIKPSPISELYEAFTDRGVLYITKDGSKLFHGNL
YDLDKGMKNLTEAAMSGPRVDMMKPLEDSMLVYKAKNEKHVVTIFTDVSCGYCRKLHNEMQEYNDLGITVRYLAFPRAGV
PSANADEMESVWCAADPLKAMGAAKNGKAVKQASCDAKIKEQYELGQAFGINGTPAIILEDGTLIPGYQPPKALLRTLES
VQ

Sequences:

>Translated_242_residues
MKFTRTFSLIAAMMIAPAAFAASSSTGDDTEALKQKLSDALSVEVISIKPSPISELYEAFTDRGVLYITKDGSKLFHGNL
YDLDKGMKNLTEAAMSGPRVDMMKPLEDSMLVYKAKNEKHVVTIFTDVSCGYCRKLHNEMQEYNDLGITVRYLAFPRAGV
PSANADEMESVWCAADPLKAMGAAKNGKAVKQASCDAKIKEQYELGQAFGINGTPAIILEDGTLIPGYQPPKALLRTLES
VQ
>Mature_242_residues
MKFTRTFSLIAAMMIAPAAFAASSSTGDDTEALKQKLSDALSVEVISIKPSPISELYEAFTDRGVLYITKDGSKLFHGNL
YDLDKGMKNLTEAAMSGPRVDMMKPLEDSMLVYKAKNEKHVVTIFTDVSCGYCRKLHNEMQEYNDLGITVRYLAFPRAGV
PSANADEMESVWCAADPLKAMGAAKNGKAVKQASCDAKIKEQYELGQAFGINGTPAIILEDGTLIPGYQPPKALLRTLES
VQ

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbC is reoxidized by a yet uncharacterized protein. Also acts as a disulfide isomerase [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1789260, Length=237, Percent_Identity=43.4599156118143, Blast_Score=204, Evalue=4e-54,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018950
- InterPro:   IPR009094
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10411 DsbC_N [H]

EC number: 5.3.4.1

Molecular weight: Translated: 26360; Mature: 26360

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFTRTFSLIAAMMIAPAAFAASSSTGDDTEALKQKLSDALSVEVISIKPSPISELYEAF
CCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHH
TDRGVLYITKDGSKLFHGNLYDLDKGMKNLTEAAMSGPRVDMMKPLEDSMLVYKAKNEKH
HCCCEEEEECCCCEEECCCHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCEEEEEECCCCE
VVTIFTDVSCGYCRKLHNEMQEYNDLGITVRYLAFPRAGVPSANADEMESVWCAADPLKA
EEEEEECCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCCHHHH
MGAAKNGKAVKQASCDAKIKEQYELGQAFGINGTPAIILEDGTLIPGYQPPKALLRTLES
HCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEECCEECCCCCCHHHHHHHHHH
VQ
CC
>Mature Secondary Structure
MKFTRTFSLIAAMMIAPAAFAASSSTGDDTEALKQKLSDALSVEVISIKPSPISELYEAF
CCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHH
TDRGVLYITKDGSKLFHGNLYDLDKGMKNLTEAAMSGPRVDMMKPLEDSMLVYKAKNEKH
HCCCEEEEECCCCEEECCCHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCEEEEEECCCCE
VVTIFTDVSCGYCRKLHNEMQEYNDLGITVRYLAFPRAGVPSANADEMESVWCAADPLKA
EEEEEECCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCCHHHH
MGAAKNGKAVKQASCDAKIKEQYELGQAFGINGTPAIILEDGTLIPGYQPPKALLRTLES
HCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEECCEECCCCCCHHHHHHHHHH
VQ
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8168497 [H]