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The map label for this gene is yfiC [C]

Identifier: 167622798

GI number: 167622798

Start: 1069418

End: 1070158

Strand: Reverse

Name: yfiC [C]

Synonym: Shal_0858

Alternate gene names: 167622798

Gene position: 1070158-1069418 (Counterclockwise)

Preceding gene: 167622803

Following gene: 167622797

Centisome position: 20.47

GC content: 48.18

Gene sequence:

>741_bases
ATGCCTTTTACCTTCAAATTATTTCATGTCGATGATAGCCGTTGCGGCATGCCCGTCAGCACCGATGGTGTACTTTTGGG
CGCATGGGCGCCATTAGTTCAAGCAAAAACCATACTCGATATCGGCGCAGGCAGTGGCCTGTTAAGCCTGATGGCTGCAC
AACGTAGTCAAGCTAAGATCACCGCGATTGAGCTCGACAACGATGCCGCCCTAGACTGCCAACAAAACTTCGATGCCAGC
CATTGGTCCGAACGTCTTGAGATTATCTGCTGCGATATCCAAGCCTATTGCCAGCGCGAGCAAGCGCGTCAGTTTGATCA
TATCATCTGCAACCCTCCCTATTTTGCTAACGGCCCCCAGTCGAGCAAGTTCTCAAGAGCTACGGCGCGCCATACTGACA
GTTTAAGTTTCGACGCTTTGCTACAGGCGATTAAGCAACTATTGGCACCCGAGGGACAGGCCAGCCTAATTTTACCGACG
GAGTCTGTCAGCCTGCTTGAGGCAATTTTGTCGACGTATAATTTGAGACTTTGTCATAAACTGCTAGCTGCAAGCGTTGA
AGGTAAAGCACCGAATCGTCAAATACTGGTGCTTGGCCATGATTTAAAAGCAAAAAAAATTCACAATTTCGGCACTGAGT
TACAGGCGGTTGCTCAACAACAGCTTTATATCCGAGAGAAAACCGGTCACTACAGTCTGGCCTTTACCCTGCTGAGTCAG
GATTTTTATTTAAAGCTTTAA

Upstream 100 bases:

>100_bases
CTCCTGCAAAGCATTAACAATTAAACCTAGATTAGTAGATTACGCTACACGTTTGATTAGCGTACAATTAGCCGAATAGT
CCAAACTAACTCTTGTTGCA

Downstream 100 bases:

>100_bases
GGATCTGGCGATCTAATCGTTTAAAGTCGCTTCTATAAGCATTATAATATCCGGCTATTATTTATTGAGATGCCACGCAT
GCAATTTGAAGATCTCCAGC

Product: methyltransferase small

Products: NA

Alternate protein names: tRNA m6A37 methyltransferase

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MPFTFKLFHVDDSRCGMPVSTDGVLLGAWAPLVQAKTILDIGAGSGLLSLMAAQRSQAKITAIELDNDAALDCQQNFDAS
HWSERLEIICCDIQAYCQREQARQFDHIICNPPYFANGPQSSKFSRATARHTDSLSFDALLQAIKQLLAPEGQASLILPT
ESVSLLEAILSTYNLRLCHKLLAASVEGKAPNRQILVLGHDLKAKKIHNFGTELQAVAQQQLYIREKTGHYSLAFTLLSQ
DFYLKL

Sequences:

>Translated_246_residues
MPFTFKLFHVDDSRCGMPVSTDGVLLGAWAPLVQAKTILDIGAGSGLLSLMAAQRSQAKITAIELDNDAALDCQQNFDAS
HWSERLEIICCDIQAYCQREQARQFDHIICNPPYFANGPQSSKFSRATARHTDSLSFDALLQAIKQLLAPEGQASLILPT
ESVSLLEAILSTYNLRLCHKLLAASVEGKAPNRQILVLGHDLKAKKIHNFGTELQAVAQQQLYIREKTGHYSLAFTLLSQ
DFYLKL
>Mature_245_residues
PFTFKLFHVDDSRCGMPVSTDGVLLGAWAPLVQAKTILDIGAGSGLLSLMAAQRSQAKITAIELDNDAALDCQQNFDASH
WSERLEIICCDIQAYCQREQARQFDHIICNPPYFANGPQSSKFSRATARHTDSLSFDALLQAIKQLLAPEGQASLILPTE
SVSLLEAILSTYNLRLCHKLLAASVEGKAPNRQILVLGHDLKAKKIHNFGTELQAVAQQQLYIREKTGHYSLAFTLLSQD
FYLKL

Specific function: Specifically methylates the adenine in position 37 of tRNA(Val)

COG id: COG4123

COG function: function code R; Predicted O-methyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family

Homologues:

Organism=Escherichia coli, GI87082131, Length=246, Percent_Identity=39.4308943089431, Blast_Score=154, Evalue=6e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TRMN6_SHEHH (B0TUD3)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001673092.1
- ProteinModelPortal:   B0TUD3
- SMR:   B0TUD3
- GeneID:   5902915
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_0858
- HOGENOM:   HBG307609
- OMA:   FKQFHIN
- ProtClustDB:   CLSK982034
- BioCyc:   SHAL458817:SHAL_0858-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01872
- InterPro:   IPR002052
- InterPro:   IPR002296
- InterPro:   IPR020596
- InterPro:   IPR007848
- InterPro:   IPR022882
- PRINTS:   PR00507

Pfam domain/function: PF05175 MTS

EC number: =2.1.1.55

Molecular weight: Translated: 27204; Mature: 27072

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS00092 N6_MTASE; PS01131 RRNA_A_DIMETH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFTFKLFHVDDSRCGMPVSTDGVLLGAWAPLVQAKTILDIGAGSGLLSLMAAQRSQAKI
CCEEEEEEEECCCCCCCCCCCCCEEEECHHHHHHHHHHEEECCCCHHHHHHHHHCCCCEE
TAIELDNDAALDCQQNFDASHWSERLEIICCDIQAYCQREQARQFDHIICNPPYFANGPQ
EEEEECCCCCCCHHHCCCHHHHHCCEEEEEECHHHHHHHHHHHHHCEEEECCCCCCCCCC
SSKFSRATARHTDSLSFDALLQAIKQLLAPEGQASLILPTESVSLLEAILSTYNLRLCHK
CCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHH
LLAASVEGKAPNRQILVLGHDLKAKKIHNFGTELQAVAQQQLYIREKTGHYSLAFTLLSQ
HHHHHCCCCCCCCEEEEEECCCCHHHHHHCCHHHHHHHHHHHHEEECCCCEEEEEEEECC
DFYLKL
CEEEEC
>Mature Secondary Structure 
PFTFKLFHVDDSRCGMPVSTDGVLLGAWAPLVQAKTILDIGAGSGLLSLMAAQRSQAKI
CEEEEEEEECCCCCCCCCCCCCEEEECHHHHHHHHHHEEECCCCHHHHHHHHHCCCCEE
TAIELDNDAALDCQQNFDASHWSERLEIICCDIQAYCQREQARQFDHIICNPPYFANGPQ
EEEEECCCCCCCHHHCCCHHHHHCCEEEEEECHHHHHHHHHHHHHCEEEECCCCCCCCCC
SSKFSRATARHTDSLSFDALLQAIKQLLAPEGQASLILPTESVSLLEAILSTYNLRLCHK
CCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHH
LLAASVEGKAPNRQILVLGHDLKAKKIHNFGTELQAVAQQQLYIREKTGHYSLAFTLLSQ
HHHHHCCCCCCCCEEEEEECCCCHHHHHHCCHHHHHHHHHHHHEEECCCCEEEEEEEECC
DFYLKL
CEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA