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The map label for this gene is mdtA [H]

Identifier: 167622795

GI number: 167622795

Start: 1065929

End: 1067158

Strand: Reverse

Name: mdtA [H]

Synonym: Shal_0855

Alternate gene names: 167622795

Gene position: 1067158-1065929 (Counterclockwise)

Preceding gene: 167622797

Following gene: 167622794

Centisome position: 20.42

GC content: 48.13

Gene sequence:

>1230_bases
ATGATAAATAAAATAAAAACCATCCTTCGGAGAATGACGCCTCTCTTTATTCTTTTAGGCTTCATTATTGCGGCTCAACT
CCTGATCAGTACCAAGGAAGCACCAGAACAGAAAGCGGATGAGGTTCCAGTTCCGATTGTCGATGTCACACAAGTTCAGG
TGCAAACCGTGTCGTTAAACCTGCCTTCATACGGTATTGTTAGCCCTAAATATAAGACTCAGTTAGTCACCGAAGTCCAG
GGTCGCATGTTGTCTATCTCAAATAACTTTGTTGCTGGCGGCGTGGTAAAAAAAGGTGATGAGTTGGCCGTTATTGAGCC
TTCTGATTACGAAGCGGACTTAATGCAGGCTCAAGCCTCTCTGGCAAAAGCCAAGGCAGCCCTAGAAGAGGAGCGCGCGA
AAGGTGAAGTTGCCAAGAATGACTGGAAGGGTTATGACGGCGGCATTCCCCCAGAGCTTGGACTACGTCTCCCGCAGTTA
AAACAAGAACAAGCCAATGTAAAGTTTCAACAAGCTGCGCTTGCCCGTGCACAACGCAACTTAGAGCGCACCGTTATTCG
CGCACCTTTCGATGGCATTATCAAGGCCCGTAACGTCGATCTTGGTCAGTATGTCACCCTTGGCACGAACTTAGGCGAGC
TATACGACACTCGTATCGCCGAAGTGAGACTCCCCCTATCAAATAGCGACTTGGCTTATCTTGAGTCGGTCGAGAACCCC
GACACGGATGTGATATTAAGTGCCGACTTGGCTGGTAAAACCATCACATGGCAAGGACAGATAGTTCGCAGCGAAGGGGT
CATCGATGCCGAAAACCGCATGGTTTATTTGGTAGCGGAGGTGAAAGATCCCTACCTTCGAGGTAATCGGAACGAAGGCC
AGCTGCCGCTAAAATACGGCACCTTTGTGACCGCCATCATCAAGGGACGCACTGTCGAGGGTATCGTAAAACTCCCACGT
CATTTGGTTCGCGATAATCGAGTCACCATAGTTAACAGCGATAACAGCATCGAGCTCAGACAGGTCAATGTGGTCAAAAG
CGATCTCGATAATGTCTACATTAAAGACAGCCTTGTCGATGGTGAACGTATATCGCTCACCAACCTCACCAATATTGAAG
ATGGTCAAGTGGTAAAAGTCTTAGGCGAAGACGCCAATTCATCCCAAGATTCTGACACTGATAATAGCGACACTAGCGAA
GAGCAACTTGCCAGTGCAGGAGTTCAATAA

Upstream 100 bases:

>100_bases
CAAATTTAAACATATTAGTTACAAATAAAGTTTTCACCTTGCCCTTGAGTCTGGTAATTTATGCAATCAGAAGAAGTCTT
TGCATGGAAAAGCAGAACAG

Downstream 100 bases:

>100_bases
TGACCACTGAAAACGACACCCAGAAAGGGATTATCGCCTGGTTTGCCCGCAACAGTGTGGCAGCCAATCTATTGATGTGG
ATTTTGATCATAGGCGGCTT

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MINKIKTILRRMTPLFILLGFIIAAQLLISTKEAPEQKADEVPVPIVDVTQVQVQTVSLNLPSYGIVSPKYKTQLVTEVQ
GRMLSISNNFVAGGVVKKGDELAVIEPSDYEADLMQAQASLAKAKAALEEERAKGEVAKNDWKGYDGGIPPELGLRLPQL
KQEQANVKFQQAALARAQRNLERTVIRAPFDGIIKARNVDLGQYVTLGTNLGELYDTRIAEVRLPLSNSDLAYLESVENP
DTDVILSADLAGKTITWQGQIVRSEGVIDAENRMVYLVAEVKDPYLRGNRNEGQLPLKYGTFVTAIIKGRTVEGIVKLPR
HLVRDNRVTIVNSDNSIELRQVNVVKSDLDNVYIKDSLVDGERISLTNLTNIEDGQVVKVLGEDANSSQDSDTDNSDTSE
EQLASAGVQ

Sequences:

>Translated_409_residues
MINKIKTILRRMTPLFILLGFIIAAQLLISTKEAPEQKADEVPVPIVDVTQVQVQTVSLNLPSYGIVSPKYKTQLVTEVQ
GRMLSISNNFVAGGVVKKGDELAVIEPSDYEADLMQAQASLAKAKAALEEERAKGEVAKNDWKGYDGGIPPELGLRLPQL
KQEQANVKFQQAALARAQRNLERTVIRAPFDGIIKARNVDLGQYVTLGTNLGELYDTRIAEVRLPLSNSDLAYLESVENP
DTDVILSADLAGKTITWQGQIVRSEGVIDAENRMVYLVAEVKDPYLRGNRNEGQLPLKYGTFVTAIIKGRTVEGIVKLPR
HLVRDNRVTIVNSDNSIELRQVNVVKSDLDNVYIKDSLVDGERISLTNLTNIEDGQVVKVLGEDANSSQDSDTDNSDTSE
EQLASAGVQ
>Mature_409_residues
MINKIKTILRRMTPLFILLGFIIAAQLLISTKEAPEQKADEVPVPIVDVTQVQVQTVSLNLPSYGIVSPKYKTQLVTEVQ
GRMLSISNNFVAGGVVKKGDELAVIEPSDYEADLMQAQASLAKAKAALEEERAKGEVAKNDWKGYDGGIPPELGLRLPQL
KQEQANVKFQQAALARAQRNLERTVIRAPFDGIIKARNVDLGQYVTLGTNLGELYDTRIAEVRLPLSNSDLAYLESVENP
DTDVILSADLAGKTITWQGQIVRSEGVIDAENRMVYLVAEVKDPYLRGNRNEGQLPLKYGTFVTAIIKGRTVEGIVKLPR
HLVRDNRVTIVNSDNSIELRQVNVVKSDLDNVYIKDSLVDGERISLTNLTNIEDGQVVKVLGEDANSSQDSDTDNSDTSE
EQLASAGVQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=348, Percent_Identity=24.4252873563218, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789929, Length=389, Percent_Identity=24.6786632390745, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 44922; Mature: 44922

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINKIKTILRRMTPLFILLGFIIAAQLLISTKEAPEQKADEVPVPIVDVTQVQVQTVSLN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCEEECCEEEEEEEEEE
LPSYGIVSPKYKTQLVTEVQGRMLSISNNFVAGGVVKKGDELAVIEPSDYEADLMQAQAS
CCCCCCCCCCHHHHHHHHHCCEEEEECCCEEECCEEECCCCEEEECCCCCHHHHHHHHHH
LAKAKAALEEERAKGEVAKNDWKGYDGGIPPELGLRLPQLKQEQANVKFQQAALARAQRN
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHCCHHHHHHHHHHHHH
LERTVIRAPFDGIIKARNVDLGQYVTLGTNLGELYDTRIAEVRLPLSNSDLAYLESVENP
HHHHEEECCHHHHEEECCCCCCCEEEECCCHHHHHHCEEEEEEECCCCCCHHHHHHCCCC
DTDVILSADLAGKTITWQGQIVRSEGVIDAENRMVYLVAEVKDPYLRGNRNEGQLPLKYG
CCCEEEEECCCCCEEEECCEEEECCCEEECCCCEEEEEEECCCCHHCCCCCCCCEEEEHH
TFVTAIIKGRTVEGIVKLPRHLVRDNRVTIVNSDNSIELRQVNVVKSDLDNVYIKDSLVD
HEEEEHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEHHHHHCCCCEEEEECCCC
GERISLTNLTNIEDGQVVKVLGEDANSSQDSDTDNSDTSEEQLASAGVQ
CCEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHCCCC
>Mature Secondary Structure
MINKIKTILRRMTPLFILLGFIIAAQLLISTKEAPEQKADEVPVPIVDVTQVQVQTVSLN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCEEECCEEEEEEEEEE
LPSYGIVSPKYKTQLVTEVQGRMLSISNNFVAGGVVKKGDELAVIEPSDYEADLMQAQAS
CCCCCCCCCCHHHHHHHHHCCEEEEECCCEEECCEEECCCCEEEECCCCCHHHHHHHHHH
LAKAKAALEEERAKGEVAKNDWKGYDGGIPPELGLRLPQLKQEQANVKFQQAALARAQRN
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHCCHHHHHHHHHHHHH
LERTVIRAPFDGIIKARNVDLGQYVTLGTNLGELYDTRIAEVRLPLSNSDLAYLESVENP
HHHHEEECCHHHHEEECCCCCCCEEEECCCHHHHHHCEEEEEEECCCCCCHHHHHHCCCC
DTDVILSADLAGKTITWQGQIVRSEGVIDAENRMVYLVAEVKDPYLRGNRNEGQLPLKYG
CCCEEEEECCCCCEEEECCEEEECCCEEECCCCEEEEEEECCCCHHCCCCCCCCEEEEHH
TFVTAIIKGRTVEGIVKLPRHLVRDNRVTIVNSDNSIELRQVNVVKSDLDNVYIKDSLVD
HEEEEHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEHHHHHCCCCEEEEECCCC
GERISLTNLTNIEDGQVVKVLGEDANSSQDSDTDNSDTSEEQLASAGVQ
CCEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]