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The map label for this gene is 167622781

Identifier: 167622781

GI number: 167622781

Start: 1043923

End: 1045572

Strand: Direct

Name: 167622781

Synonym: Shal_0841

Alternate gene names: NA

Gene position: 1043923-1045572 (Clockwise)

Preceding gene: 167622778

Following gene: 167622782

Centisome position: 19.97

GC content: 50.67

Gene sequence:

>1650_bases
ATGCTAACAGCTGGTAATGGAATGAGACAAGCTGAGAATCATCAATGCGATACCGTCATCGCCGGAGCTGGCGTTGCTGG
TCTAGTCACCGCGCTTGAATTACTCAAGCATGGGCAGACGGTCTATCTTGTCGACCGTGATACGGCAGAGAGGATCGGTG
GCCTCGCCCGCTGGGCTTTTGGGGGGATGGCCTTGTGCGGAACTCGGCAGCAGAGGCGGATGAAGATCCCCGATGACTCG
GCTCTTCTGCTTCGGGATTGGCATAGTTTTGCCGATTTTGCCAAAGAGGATCTCTGGCCTAAGGCTTGGGCAAAAGAGTA
TGCCGAACATAATAATGAAAAGGTCTATCAGTGGCTAACTCGCTTAGGTCTCAAGTTTCTGCCTGCAGTCAACTGGGTGG
AGCGAGGGCTGTTCGTTCCAGGTAATTCAGTGCCTCGCTACCATGTGCTGTGGGGAACGGGTAAGACGCTAGTCGAGACC
GTAATGGCTAAGTTGACCCCCTATGTCAGAACGGGAAAGCTTAATATTCTTCATCGTCACAAGGTTGTGCGCCCTACTAC
CGATAGGGGAACCGTCATCGGCGTCGAAGTTAAAAATGAACAGAGTCAGGCTGTGTTTTTGATCAATGCTGCTCATGTTG
TCATTGCCTGTGGTGGCATCAATGGCAGCAGCGAAAGGGTAAAGCAGAATTGGAAGCTCCCCTGTGAGCAGGTGGCCGAG
GCACCATTTAATGGCGCTAATCCTATTTCAGATGGCCAGCTTCATGACGAGATAGAGGCCCAAGGCGGCAAGGTGACTCA
CATCGATAAGATGTGGAACTATGCGGCTGGAATCGCCCACCCTCAGGCAGAGTTTGAGGGGCATGGTTTAAGCTTGATCC
CCTGTAAATCGGCCCTTTGGCTCGATCACCTTGGAAAGCGGATCGGTCCACAACCTCTGGTTACCGGGTTTGACACCAAC
TATCTGTGTCAGCAGCTTGCGGGGCTGAGTAAGCCTTGGACCTGGCAGGTACTGAATTGGGACGTAGCCGCAAAAGAGCT
GGCGGTGTCAGGCTCAGAGCATAACCCCTCTATTAGAGATAAAAAAATATTCAGCTTTTTGAAAGAGATATTTTTCGGTA
ATCATAGGTTAGTGGAAGAGTTAGTACAGCAATCTGCAGATGTACTCTGCGCCGATACACTCGACGAACTGACGGATAAG
ATGAACGCTCTGGCTAAGAAAAACTATATTAATGGTGCCGATTTAGCGCAAGAGATCGCGCTGTACGATCGGCGAGCGGC
CGATGTAAGGTTGCATAATGATGAGCAGCTAAGACGTATTAATCATACCAGACAATGGAAACCCGATAGGTTACGAACCC
GTAAGCCCGGACCAATATTATCGTCTGGAATGGCAAAGAGAGATAAGCTGATTGCCATCAGACTCAAGCTGATCAGTCGA
AAGAGCCTAGGCGGACTGCAAACTAACTTATCTAGCCAAGTATTGGATGTGCAGGGTAAACCTATTGGCGGCTTATATTG
TGTTGGTGAGGCGGCGGGTTTTGGTGGTGGCGGCGCCAACGGTGCTCGCTCTTTGGAGGGGACATTTTTATCCGCTTGTA
TCTTAACTGCCCGCAATGCGGCGACTGCTATTGTTGGCAGTCATAGCTAG

Upstream 100 bases:

>100_bases
TGATAAAGTTGTCGGGAGGAACTCTTTGCATATTTAACCCATTAGGTAATTTTTACTATGGCCAGAAGGTGTTATTCATA
ACAGTATAAATATCATTCAT

Downstream 100 bases:

>100_bases
CCATAAATAACGAAAAATAAAAAAAGAAATCTAAGGAGAGCACATTGAAAAGGACTGCAGCTTGGCTGACACGTTACGCC
CTAGAGCAACTGAATATTAA

Product: fumarate reductase/succinate dehydrogenase flavoprotein domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MLTAGNGMRQAENHQCDTVIAGAGVAGLVTALELLKHGQTVYLVDRDTAERIGGLARWAFGGMALCGTRQQRRMKIPDDS
ALLLRDWHSFADFAKEDLWPKAWAKEYAEHNNEKVYQWLTRLGLKFLPAVNWVERGLFVPGNSVPRYHVLWGTGKTLVET
VMAKLTPYVRTGKLNILHRHKVVRPTTDRGTVIGVEVKNEQSQAVFLINAAHVVIACGGINGSSERVKQNWKLPCEQVAE
APFNGANPISDGQLHDEIEAQGGKVTHIDKMWNYAAGIAHPQAEFEGHGLSLIPCKSALWLDHLGKRIGPQPLVTGFDTN
YLCQQLAGLSKPWTWQVLNWDVAAKELAVSGSEHNPSIRDKKIFSFLKEIFFGNHRLVEELVQQSADVLCADTLDELTDK
MNALAKKNYINGADLAQEIALYDRRAADVRLHNDEQLRRINHTRQWKPDRLRTRKPGPILSSGMAKRDKLIAIRLKLISR
KSLGGLQTNLSSQVLDVQGKPIGGLYCVGEAAGFGGGGANGARSLEGTFLSACILTARNAATAIVGSHS

Sequences:

>Translated_549_residues
MLTAGNGMRQAENHQCDTVIAGAGVAGLVTALELLKHGQTVYLVDRDTAERIGGLARWAFGGMALCGTRQQRRMKIPDDS
ALLLRDWHSFADFAKEDLWPKAWAKEYAEHNNEKVYQWLTRLGLKFLPAVNWVERGLFVPGNSVPRYHVLWGTGKTLVET
VMAKLTPYVRTGKLNILHRHKVVRPTTDRGTVIGVEVKNEQSQAVFLINAAHVVIACGGINGSSERVKQNWKLPCEQVAE
APFNGANPISDGQLHDEIEAQGGKVTHIDKMWNYAAGIAHPQAEFEGHGLSLIPCKSALWLDHLGKRIGPQPLVTGFDTN
YLCQQLAGLSKPWTWQVLNWDVAAKELAVSGSEHNPSIRDKKIFSFLKEIFFGNHRLVEELVQQSADVLCADTLDELTDK
MNALAKKNYINGADLAQEIALYDRRAADVRLHNDEQLRRINHTRQWKPDRLRTRKPGPILSSGMAKRDKLIAIRLKLISR
KSLGGLQTNLSSQVLDVQGKPIGGLYCVGEAAGFGGGGANGARSLEGTFLSACILTARNAATAIVGSHS
>Mature_549_residues
MLTAGNGMRQAENHQCDTVIAGAGVAGLVTALELLKHGQTVYLVDRDTAERIGGLARWAFGGMALCGTRQQRRMKIPDDS
ALLLRDWHSFADFAKEDLWPKAWAKEYAEHNNEKVYQWLTRLGLKFLPAVNWVERGLFVPGNSVPRYHVLWGTGKTLVET
VMAKLTPYVRTGKLNILHRHKVVRPTTDRGTVIGVEVKNEQSQAVFLINAAHVVIACGGINGSSERVKQNWKLPCEQVAE
APFNGANPISDGQLHDEIEAQGGKVTHIDKMWNYAAGIAHPQAEFEGHGLSLIPCKSALWLDHLGKRIGPQPLVTGFDTN
YLCQQLAGLSKPWTWQVLNWDVAAKELAVSGSEHNPSIRDKKIFSFLKEIFFGNHRLVEELVQQSADVLCADTLDELTDK
MNALAKKNYINGADLAQEIALYDRRAADVRLHNDEQLRRINHTRQWKPDRLRTRKPGPILSSGMAKRDKLIAIRLKLISR
KSLGGLQTNLSSQVLDVQGKPIGGLYCVGEAAGFGGGGANGARSLEGTFLSACILTARNAATAIVGSHS

Specific function: Able to catalyze the elimination of the C-1 and C-2 hydrogen atoms of the A-ring from the polycyclic ring structure of 3-ketosteroids, but the ketosteroid dehydrogenase activity is low compared to KsdD in the cholesterol degradation process. The low activ

COG id: COG3573

COG function: function code R; Predicted oxidoreductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase 2 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 60426; Mature: 60426

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTAGNGMRQAENHQCDTVIAGAGVAGLVTALELLKHGQTVYLVDRDTAERIGGLARWAF
CCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHH
GGMALCGTRQQRRMKIPDDSALLLRDWHSFADFAKEDLWPKAWAKEYAEHNNEKVYQWLT
CCCCEECCCHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHH
RLGLKFLPAVNWVERGLFVPGNSVPRYHVLWGTGKTLVETVMAKLTPYVRTGKLNILHRH
HHHHHHHHHHHHHHCCEECCCCCCCEEEEEECCCHHHHHHHHHHHCCCEECCEEEEEECC
KVVRPTTDRGTVIGVEVKNEQSQAVFLINAAHVVIACGGINGSSERVKQNWKLPCEQVAE
CEECCCCCCCCEEEEEECCCCCCEEEEEEEEEEEEEECCCCCCHHHHHHCCCCCHHHHHC
APFNGANPISDGQLHDEIEAQGGKVTHIDKMWNYAAGIAHPQAEFEGHGLSLIPCKSALW
CCCCCCCCCCCCCHHHHHHCCCCEEEEHHHHHHHHHCCCCCCHHCCCCCEEEECCCHHHH
LDHLGKRIGPQPLVTGFDTNYLCQQLAGLSKPWTWQVLNWDVAAKELAVSGSEHNPSIRD
HHHHHHHCCCCCEEECCCHHHHHHHHHCCCCCCEEEEEECCHHHHHHHCCCCCCCCCCHH
KKIFSFLKEIFFGNHRLVEELVQQSADVLCADTLDELTDKMNALAKKNYINGADLAQEIA
HHHHHHHHHHHCCCHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LYDRRAADVRLHNDEQLRRINHTRQWKPDRLRTRKPGPILSSGMAKRDKLIAIRLKLISR
HHHCCCCCEEECCHHHHHHHHHCCCCCCHHHCCCCCCCCHHCCCCHHCCEEEEEHHHHHH
KSLGGLQTNLSSQVLDVQGKPIGGLYCVGEAAGFGGGGANGARSLEGTFLSACILTARNA
HCCCCHHHCCCHHEEECCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
ATAIVGSHS
CEEEECCCC
>Mature Secondary Structure
MLTAGNGMRQAENHQCDTVIAGAGVAGLVTALELLKHGQTVYLVDRDTAERIGGLARWAF
CCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHH
GGMALCGTRQQRRMKIPDDSALLLRDWHSFADFAKEDLWPKAWAKEYAEHNNEKVYQWLT
CCCCEECCCHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHH
RLGLKFLPAVNWVERGLFVPGNSVPRYHVLWGTGKTLVETVMAKLTPYVRTGKLNILHRH
HHHHHHHHHHHHHHCCEECCCCCCCEEEEEECCCHHHHHHHHHHHCCCEECCEEEEEECC
KVVRPTTDRGTVIGVEVKNEQSQAVFLINAAHVVIACGGINGSSERVKQNWKLPCEQVAE
CEECCCCCCCCEEEEEECCCCCCEEEEEEEEEEEEEECCCCCCHHHHHHCCCCCHHHHHC
APFNGANPISDGQLHDEIEAQGGKVTHIDKMWNYAAGIAHPQAEFEGHGLSLIPCKSALW
CCCCCCCCCCCCCHHHHHHCCCCEEEEHHHHHHHHHCCCCCCHHCCCCCEEEECCCHHHH
LDHLGKRIGPQPLVTGFDTNYLCQQLAGLSKPWTWQVLNWDVAAKELAVSGSEHNPSIRD
HHHHHHHCCCCCEEECCCHHHHHHHHHCCCCCCEEEEEECCHHHHHHHCCCCCCCCCCHH
KKIFSFLKEIFFGNHRLVEELVQQSADVLCADTLDELTDKMNALAKKNYINGADLAQEIA
HHHHHHHHHHHCCCHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LYDRRAADVRLHNDEQLRRINHTRQWKPDRLRTRKPGPILSSGMAKRDKLIAIRLKLISR
HHHCCCCCEEECCHHHHHHHHHCCCCCCHHHCCCCCCCCHHCCCCHHCCEEEEEHHHHHH
KSLGGLQTNLSSQVLDVQGKPIGGLYCVGEAAGFGGGGANGARSLEGTFLSACILTARNA
HCCCCHHHCCCHHEEECCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
ATAIVGSHS
CEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA