Click here to switch to the map view.

The map label for this gene is yhcK [H]

Identifier: 167622678

GI number: 167622678

Start: 917794

End: 919653

Strand: Direct

Name: yhcK [H]

Synonym: Shal_0738

Alternate gene names: 167622678

Gene position: 917794-919653 (Clockwise)

Preceding gene: 167622677

Following gene: 167622679

Centisome position: 17.56

GC content: 42.9

Gene sequence:

>1860_bases
ATGGTACTCTCTTTGCTGGTGAGTTTTACCTCTTTGACGAGCCTATGCGGATATGCAGCCGATCCTTTTGTTCAATTAGA
GCAAGATCTTGAAGACTCATCTCCTGCCAATGCGCTGATCTTACTTGGTCAGTTTAAACTCGACGCTGACAACGCCAGCA
TTCAAGAGTTAGCCCAATTACGTTTTTTATATGGCAAGCAATATGAGCGAAACCGTAAGCTAGATCAGGCGATAGCCAGC
TATGATAAGGCGATTGCACTGATGCAGCCATTAGGTGTATCGGATCTACTCATTGAAAGTCATCTCGAACGTTCTTTCGT
CCTCTACTTAAAGACTAACGATCCCGAGGCTTATTGTGTCGATAGAAAAAAGGCCTTGGTGTTCGCTAGGCAGCAAGGTA
ATAACGAGCTGCTAGCTAAGACGTTAACTCAGAATGCATTTTGCTATAACAAAGTCACCAACGTTCATCAAGGGCTCGCC
TTGCTTGATGAAGCTATGCTGATTATCAACACCGACGGCAGTGCAAATCATACCCGTAAGGCGATGATCTATAATGCGAC
TGGTTCTCTCTATCGCACCGTGGGTCTGCATAAGCGCGGCTATATGAATTTTGAAAAAGCCTACCAGGCATGGAGTGAGG
TCGATGATACTCAAGACATGTTTAATATGCTGCATAACATGATCAGCGAGGCGATTAAGCTGCGGGATTGGGAGAAGGCG
AGACACAATATTGAACGACAGTTTGCTTTGGTTAGATCTACACCTGAATTTGCAGATTTTGGTTTTTTTGCCCACCTAAA
TGCTGGGCGAGTCGAGTTAGCGACACATCATTATGTAGAAGCAATAGAACATCTTAAGCATGCTATATCTTTGAAAGAAA
CAACTCGTGAGCAGTATTTTATTAGCAGTAGCTATCAGTTTCTTTCCTTAGCGTATCTGCGTGTAGGTGATGTAAAAAAA
GCGGCGCAAATGGCAAGCGTATTTAGGCAAGACAAGAATTTCCCTAAAAATATGTCCAGCATGATGTTAACTGCAGACGC
TATTATTGCATTTGAGCAGCATCAATATTTACCTGCGATGAATACTTTGCTCCAAGTGATCGATGAGGAACGACAAAATA
ATAAGCAGATTATCGACAATGAGGTGATCGATTCAGCGCTAGAGCATAGCGCTAAGCTGGCCGATTTTGAGAATCAGTTG
TTAGCTAACCAGTTGGCGATTAACGAGCTGAGCTTAGCGGCGGTAGCGGATAAAGCACGGATCTATGACTTAAGGCTAAG
CATCTTTTTCTTGGTGGCTATGGTGCTCCTAATTGCAATCTTGTTTCTGTGGCAATCTCGTAAAGCCTTTAAGCATAGTG
CTCAAACTGATTTTTTAACGGGTATCGCTAACCGCGCACATACCTTTAAATTTGGCCAGCGAATGCTCGATAAAGCAATT
AAGAAGCAGAGTTGCTTCGCTGTGATTATTTTTGATATCGACAATTTCAAGTTGATCAATGATCAATATGGTCACCATAT
TGGTGATTTGGCAATTAAAGCCGTTGCTAAACGCGGTGCCCGTTGGCTGAGAGGGGGCGATTTAATTGGTCGAATTGGTG
GTGAAGAGTTCTTAATTATCCTGCCTGATGCCTGTAACGCGGAGGCATCTGCTATTTCTGAACGCTTACGTGAGGGGATC
GCAGCACAACCATTTCAATTTGATGATGTGATTATTGAATTAACGGTGAGCCTAGGAGTCGCTGGATTAAAATCTCCTCA
AATGAGTTTGACTGATTTGATCCATCAAGCAGATAAAGGACTCTATAAGGCTAAATTTTCTGGCAAGAATCAAGTCTATC
TTGTTGAGCAGTTCGCTTAA

Upstream 100 bases:

>100_bases
CAGCACTGTAAATATAGTATTTCGATGTGTTAAGCTGCTTGAGGTTCATTGTAAATAATCTGGATTTCGGGTGTACACAG
TAAAAAAATGGCTCAAGATA

Downstream 100 bases:

>100_bases
TCCCGCTTTGATTACTACCTAATTACTACCTAAGCCTAATTCTCGGTATGGAGCTATCGCCTTCATTCCTGAGAATTTCA
GGGGCTCAAACTTGTATTAA

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 619; Mature: 619

Protein sequence:

>619_residues
MVLSLLVSFTSLTSLCGYAADPFVQLEQDLEDSSPANALILLGQFKLDADNASIQELAQLRFLYGKQYERNRKLDQAIAS
YDKAIALMQPLGVSDLLIESHLERSFVLYLKTNDPEAYCVDRKKALVFARQQGNNELLAKTLTQNAFCYNKVTNVHQGLA
LLDEAMLIINTDGSANHTRKAMIYNATGSLYRTVGLHKRGYMNFEKAYQAWSEVDDTQDMFNMLHNMISEAIKLRDWEKA
RHNIERQFALVRSTPEFADFGFFAHLNAGRVELATHHYVEAIEHLKHAISLKETTREQYFISSSYQFLSLAYLRVGDVKK
AAQMASVFRQDKNFPKNMSSMMLTADAIIAFEQHQYLPAMNTLLQVIDEERQNNKQIIDNEVIDSALEHSAKLADFENQL
LANQLAINELSLAAVADKARIYDLRLSIFFLVAMVLLIAILFLWQSRKAFKHSAQTDFLTGIANRAHTFKFGQRMLDKAI
KKQSCFAVIIFDIDNFKLINDQYGHHIGDLAIKAVAKRGARWLRGGDLIGRIGGEEFLIILPDACNAEASAISERLREGI
AAQPFQFDDVIIELTVSLGVAGLKSPQMSLTDLIHQADKGLYKAKFSGKNQVYLVEQFA

Sequences:

>Translated_619_residues
MVLSLLVSFTSLTSLCGYAADPFVQLEQDLEDSSPANALILLGQFKLDADNASIQELAQLRFLYGKQYERNRKLDQAIAS
YDKAIALMQPLGVSDLLIESHLERSFVLYLKTNDPEAYCVDRKKALVFARQQGNNELLAKTLTQNAFCYNKVTNVHQGLA
LLDEAMLIINTDGSANHTRKAMIYNATGSLYRTVGLHKRGYMNFEKAYQAWSEVDDTQDMFNMLHNMISEAIKLRDWEKA
RHNIERQFALVRSTPEFADFGFFAHLNAGRVELATHHYVEAIEHLKHAISLKETTREQYFISSSYQFLSLAYLRVGDVKK
AAQMASVFRQDKNFPKNMSSMMLTADAIIAFEQHQYLPAMNTLLQVIDEERQNNKQIIDNEVIDSALEHSAKLADFENQL
LANQLAINELSLAAVADKARIYDLRLSIFFLVAMVLLIAILFLWQSRKAFKHSAQTDFLTGIANRAHTFKFGQRMLDKAI
KKQSCFAVIIFDIDNFKLINDQYGHHIGDLAIKAVAKRGARWLRGGDLIGRIGGEEFLIILPDACNAEASAISERLREGI
AAQPFQFDDVIIELTVSLGVAGLKSPQMSLTDLIHQADKGLYKAKFSGKNQVYLVEQFA
>Mature_619_residues
MVLSLLVSFTSLTSLCGYAADPFVQLEQDLEDSSPANALILLGQFKLDADNASIQELAQLRFLYGKQYERNRKLDQAIAS
YDKAIALMQPLGVSDLLIESHLERSFVLYLKTNDPEAYCVDRKKALVFARQQGNNELLAKTLTQNAFCYNKVTNVHQGLA
LLDEAMLIINTDGSANHTRKAMIYNATGSLYRTVGLHKRGYMNFEKAYQAWSEVDDTQDMFNMLHNMISEAIKLRDWEKA
RHNIERQFALVRSTPEFADFGFFAHLNAGRVELATHHYVEAIEHLKHAISLKETTREQYFISSSYQFLSLAYLRVGDVKK
AAQMASVFRQDKNFPKNMSSMMLTADAIIAFEQHQYLPAMNTLLQVIDEERQNNKQIIDNEVIDSALEHSAKLADFENQL
LANQLAINELSLAAVADKARIYDLRLSIFFLVAMVLLIAILFLWQSRKAFKHSAQTDFLTGIANRAHTFKFGQRMLDKAI
KKQSCFAVIIFDIDNFKLINDQYGHHIGDLAIKAVAKRGARWLRGGDLIGRIGGEEFLIILPDACNAEASAISERLREGI
AAQPFQFDDVIIELTVSLGVAGLKSPQMSLTDLIHQADKGLYKAKFSGKNQVYLVEQFA

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1787262, Length=180, Percent_Identity=32.2222222222222, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1787802, Length=162, Percent_Identity=32.7160493827161, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1786584, Length=198, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI87082007, Length=179, Percent_Identity=32.9608938547486, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1787816, Length=170, Percent_Identity=31.7647058823529, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87081881, Length=166, Percent_Identity=35.5421686746988, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI87081977, Length=164, Percent_Identity=31.7073170731707, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI145693134, Length=165, Percent_Identity=32.1212121212121, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI1788381, Length=176, Percent_Identity=30.1136363636364, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1788085, Length=162, Percent_Identity=30.8641975308642, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1787541, Length=164, Percent_Identity=32.9268292682927, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87081974, Length=251, Percent_Identity=26.2948207171315, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI1788956, Length=169, Percent_Identity=33.7278106508876, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 69864; Mature: 69864

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLSLLVSFTSLTSLCGYAADPFVQLEQDLEDSSPANALILLGQFKLDADNASIQELAQL
CHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHH
RFLYGKQYERNRKLDQAIASYDKAIALMQPLGVSDLLIESHLERSFVLYLKTNDPEAYCV
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEEECCCCCEEEE
DRKKALVFARQQGNNELLAKTLTQNAFCYNKVTNVHQGLALLDEAMLIINTDGSANHTRK
CCHHHEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCEE
AMIYNATGSLYRTVGLHKRGYMNFEKAYQAWSEVDDTQDMFNMLHNMISEAIKLRDWEKA
EEEEECCCCHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHH
RHNIERQFALVRSTPEFADFGFFAHLNAGRVELATHHYVEAIEHLKHAISLKETTREQYF
HHHHHHHHHHHHCCCCHHHCCEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHE
ISSSYQFLSLAYLRVGDVKKAAQMASVFRQDKNFPKNMSSMMLTADAIIAFEQHQYLPAM
ECCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEEHHHCCCHHH
NTLLQVIDEERQNNKQIIDNEVIDSALEHSAKLADFENQLLANQLAINELSLAAVADKAR
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IYDLRLSIFFLVAMVLLIAILFLWQSRKAFKHSAQTDFLTGIANRAHTFKFGQRMLDKAI
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KKQSCFAVIIFDIDNFKLINDQYGHHIGDLAIKAVAKRGARWLRGGDLIGRIGGEEFLII
CCCCCEEEEEEECCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCEEEEE
LPDACNAEASAISERLREGIAAQPFQFDDVIIELTVSLGVAGLKSPQMSLTDLIHQADKG
ECCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHEEHHHCCCCCCCCCHHHHHHHHHHCCC
LYKAKFSGKNQVYLVEQFA
CEEEEECCCCEEEEEEECC
>Mature Secondary Structure
MVLSLLVSFTSLTSLCGYAADPFVQLEQDLEDSSPANALILLGQFKLDADNASIQELAQL
CHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHH
RFLYGKQYERNRKLDQAIASYDKAIALMQPLGVSDLLIESHLERSFVLYLKTNDPEAYCV
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEEECCCCCEEEE
DRKKALVFARQQGNNELLAKTLTQNAFCYNKVTNVHQGLALLDEAMLIINTDGSANHTRK
CCHHHEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCEE
AMIYNATGSLYRTVGLHKRGYMNFEKAYQAWSEVDDTQDMFNMLHNMISEAIKLRDWEKA
EEEEECCCCHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHH
RHNIERQFALVRSTPEFADFGFFAHLNAGRVELATHHYVEAIEHLKHAISLKETTREQYF
HHHHHHHHHHHHCCCCHHHCCEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHE
ISSSYQFLSLAYLRVGDVKKAAQMASVFRQDKNFPKNMSSMMLTADAIIAFEQHQYLPAM
ECCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEEHHHCCCHHH
NTLLQVIDEERQNNKQIIDNEVIDSALEHSAKLADFENQLLANQLAINELSLAAVADKAR
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IYDLRLSIFFLVAMVLLIAILFLWQSRKAFKHSAQTDFLTGIANRAHTFKFGQRMLDKAI
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KKQSCFAVIIFDIDNFKLINDQYGHHIGDLAIKAVAKRGARWLRGGDLIGRIGGEEFLII
CCCCCEEEEEEECCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCEEEEE
LPDACNAEASAISERLREGIAAQPFQFDDVIIELTVSLGVAGLKSPQMSLTDLIHQADKG
ECCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHEEHHHCCCCCCCCCHHHHHHHHHHCCC
LYKAKFSGKNQVYLVEQFA
CEEEEECCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]