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The map label for this gene is ykvO [H]

Identifier: 167622534

GI number: 167622534

Start: 719579

End: 720241

Strand: Reverse

Name: ykvO [H]

Synonym: Shal_0594

Alternate gene names: 167622534

Gene position: 720241-719579 (Counterclockwise)

Preceding gene: 167622535

Following gene: 167622533

Centisome position: 13.78

GC content: 48.27

Gene sequence:

>663_bases
ATGATACTCATTACCGGTGCCAGCAGCGGATTAGGCGCAGCGCTCGCCAAGCAGTATGGCAAAGAAAGTCCAATTTGCAT
CAGTGGTCGCAATAGCGAGCGTTTACAATTAGTCGCTACAGAAGTTTGCCAATCTTGCCAGACTCAAGTTACCGACCTTT
GCGATGCAGATGCCGTAGCAGCCCTATTCGATAGTCTAGCCACTTCGCCATCACTGATTATCCATAGTGCAGGCAGTGGC
TATTTTGGTCCTATCGAAACCCAGTCTCCACAGGCAATTCAGCAGCTGCTCAATAACAACGTCACCTCGGCAATTTTTTT
ACTACGGGAAGCGGTTAAACGTTATAAAGATCAATGCGTGACGGTGGTGATTGTTATGTCGACAGCTGCACTCACGGCGA
AAGCTGAAGAATCGACCTACTGCGCAGCAAAATGGGCAGTAAAAGGCTTAGTCGAATCCGTACGATTAGAACTAAAAAAT
AGTCCAATGAAATTAATTGCAGTTTATCCTGGAGGCATGGCCACCGATTTTTGGCCCACCAGCGGTAAAAGCGCAAACAC
CGCCAGCTTTATGACTGCAGACGAAGCAGCGAGTATGCTAAAACAGGCACTACAGAGTACCGAGCACGGCTATATTAGCG
ACCTCACTATCGCCCGTGGCTAA

Upstream 100 bases:

>100_bases
GGCCAGCAGGTAGATTTTGAGCAAGCGATTCTCGAGATTGAATAACCTCACTTAATAAAAACAACATCAGCAAACCATTT
AGCAAAGAGTAAGGACCACT

Downstream 100 bases:

>100_bases
GAAAGCAATTTTAAGAGAGTGATATAGAGAAGGATGAAGGATAAGGACGCTAAATAAAATGAAATAGCTGTCGCGTTTTC
TATACTTACAACTTAGCGTT

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MILITGASSGLGAALAKQYGKESPICISGRNSERLQLVATEVCQSCQTQVTDLCDADAVAALFDSLATSPSLIIHSAGSG
YFGPIETQSPQAIQQLLNNNVTSAIFLLREAVKRYKDQCVTVVIVMSTAALTAKAEESTYCAAKWAVKGLVESVRLELKN
SPMKLIAVYPGGMATDFWPTSGKSANTASFMTADEAASMLKQALQSTEHGYISDLTIARG

Sequences:

>Translated_220_residues
MILITGASSGLGAALAKQYGKESPICISGRNSERLQLVATEVCQSCQTQVTDLCDADAVAALFDSLATSPSLIIHSAGSG
YFGPIETQSPQAIQQLLNNNVTSAIFLLREAVKRYKDQCVTVVIVMSTAALTAKAEESTYCAAKWAVKGLVESVRLELKN
SPMKLIAVYPGGMATDFWPTSGKSANTASFMTADEAASMLKQALQSTEHGYISDLTIARG
>Mature_220_residues
MILITGASSGLGAALAKQYGKESPICISGRNSERLQLVATEVCQSCQTQVTDLCDADAVAALFDSLATSPSLIIHSAGSG
YFGPIETQSPQAIQQLLNNNVTSAIFLLREAVKRYKDQCVTVVIVMSTAALTAKAEESTYCAAKWAVKGLVESVRLELKN
SPMKLIAVYPGGMATDFWPTSGKSANTASFMTADEAASMLKQALQSTEHGYISDLTIARG

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7657478, Length=187, Percent_Identity=27.2727272727273, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=193, Percent_Identity=27.4611398963731, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI116007236, Length=234, Percent_Identity=24.7863247863248, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281364892, Length=179, Percent_Identity=29.608938547486, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 23264; Mature: 23264

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILITGASSGLGAALAKQYGKESPICISGRNSERLQLVATEVCQSCQTQVTDLCDADAVA
CEEEECCCCCHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHH
ALFDSLATSPSLIIHSAGSGYFGPIETQSPQAIQQLLNNNVTSAIFLLREAVKRYKDQCV
HHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
TVVIVMSTAALTAKAEESTYCAAKWAVKGLVESVRLELKNSPMKLIAVYPGGMATDFWPT
HHHEEEHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCC
SGKSANTASFMTADEAASMLKQALQSTEHGYISDLTIARG
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEECEEEECC
>Mature Secondary Structure
MILITGASSGLGAALAKQYGKESPICISGRNSERLQLVATEVCQSCQTQVTDLCDADAVA
CEEEECCCCCHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHH
ALFDSLATSPSLIIHSAGSGYFGPIETQSPQAIQQLLNNNVTSAIFLLREAVKRYKDQCV
HHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
TVVIVMSTAALTAKAEESTYCAAKWAVKGLVESVRLELKNSPMKLIAVYPGGMATDFWPT
HHHEEEHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCC
SGKSANTASFMTADEAASMLKQALQSTEHGYISDLTIARG
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEECEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on the CH-OH group of donors; With NAD or NADP as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]