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The map label for this gene is udp [H]

Identifier: 167622475

GI number: 167622475

Start: 644757

End: 645515

Strand: Direct

Name: udp [H]

Synonym: Shal_0535

Alternate gene names: 167622475

Gene position: 644757-645515 (Clockwise)

Preceding gene: 167622473

Following gene: 167622477

Centisome position: 12.34

GC content: 49.01

Gene sequence:

>759_bases
ATGTCTGATGTATTTCATTTAGGCTTAACGAAAGAGATGTTAGATGGTGCTAGCTTAGCGATCGTACCAGGCGATCCAGA
GCGTGTTAAGCGTATCGCCGAGTTGATGGAGAATGCGACATTTTTAGCGAGTCATCGTGAATATACCAGTTACTTGGCAT
ACATAGACGGTAAGCCTGTGGTTGTGTGTTCAACGGGTATTGGTGGCCCATCGACATCGATCGCCGTTGAGGAGTTAGCG
CAGCTTGGCGTGCGTACTTTCCTACGTGTCGGTACCACTGGTGCGATTCAGCCACATGTGAATGTGGGCGATGTGATTGT
GACTCAAGCATCGGTGCGTTTAGATGGTGCAAGCCTGCACTTCGCGCCGATGGAGTATCCAGCTGTAGCAAACTTTGAGT
GTACAACCGCTATGGTTGCCGCAAGTCGCGAAGCAGGGCTTGAGCCACATATTGGTATTACAGCATCATCAGATACCTTC
TATCCAGGCCAAGAGCGTTACGATACTGTTTCGGGTCGCATAACACGTCAATTCAAGGGGTCTATGCAAGAGTGGCAAGA
CTTAGGTGTTTTGAACTACGAGATGGAATCTTCGACGCTATTTACCATGTGTTCTTCACAAGGTTGGCGCGCGGCATGTG
TTGCGGGTGTGATTGTTAACCGTACTCAACAAGAGATCCCAGATGAAGCGACAATGAAGAAGACTGAGGTCAGTGCCGTT
TCTATCGTCGTAGCGGCAGCTAAGAAGCTACTCGCATAA

Upstream 100 bases:

>100_bases
GGCGGGTAAAGTGTGATCAGTTTAACCTTTTTAGCGTCGAGACTAGGTTAAAGTCGCATTAATTAGATTTATAAATTCAA
AAATGAAAGGGGTTTTCACG

Downstream 100 bases:

>100_bases
GCTTATGTTTATGCAGTAAAAAAGGCGCTATATGCGCCTTTTTTGTTGGTCTATAACACTCGCTTTCAAAATTGAGATTA
GAAGTGATACTTAGCAATCA

Product: uridine phosphorylase

Products: NA

Alternate protein names: UPase; UrdPase [H]

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MSDVFHLGLTKEMLDGASLAIVPGDPERVKRIAELMENATFLASHREYTSYLAYIDGKPVVVCSTGIGGPSTSIAVEELA
QLGVRTFLRVGTTGAIQPHVNVGDVIVTQASVRLDGASLHFAPMEYPAVANFECTTAMVAASREAGLEPHIGITASSDTF
YPGQERYDTVSGRITRQFKGSMQEWQDLGVLNYEMESSTLFTMCSSQGWRAACVAGVIVNRTQQEIPDEATMKKTEVSAV
SIVVAAAKKLLA

Sequences:

>Translated_252_residues
MSDVFHLGLTKEMLDGASLAIVPGDPERVKRIAELMENATFLASHREYTSYLAYIDGKPVVVCSTGIGGPSTSIAVEELA
QLGVRTFLRVGTTGAIQPHVNVGDVIVTQASVRLDGASLHFAPMEYPAVANFECTTAMVAASREAGLEPHIGITASSDTF
YPGQERYDTVSGRITRQFKGSMQEWQDLGVLNYEMESSTLFTMCSSQGWRAACVAGVIVNRTQQEIPDEATMKKTEVSAV
SIVVAAAKKLLA
>Mature_251_residues
SDVFHLGLTKEMLDGASLAIVPGDPERVKRIAELMENATFLASHREYTSYLAYIDGKPVVVCSTGIGGPSTSIAVEELAQ
LGVRTFLRVGTTGAIQPHVNVGDVIVTQASVRLDGASLHFAPMEYPAVANFECTTAMVAASREAGLEPHIGITASSDTFY
PGQERYDTVSGRITRQFKGSMQEWQDLGVLNYEMESSTLFTMCSSQGWRAACVAGVIVNRTQQEIPDEATMKKTEVSAVS
IVVAAAKKLLA

Specific function: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synth

COG id: COG2820

COG function: function code F; Uridine phosphorylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family [H]

Homologues:

Organism=Escherichia coli, GI1790265, Length=250, Percent_Identity=74.8, Blast_Score=402, Evalue=1e-113,
Organism=Escherichia coli, GI1790844, Length=213, Percent_Identity=29.1079812206573, Blast_Score=96, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845
- InterPro:   IPR010058 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.3 [H]

Molecular weight: Translated: 27068; Mature: 26937

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVFHLGLTKEMLDGASLAIVPGDPERVKRIAELMENATFLASHREYTSYLAYIDGKPV
CCCEEECCCCHHHHCCCCEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHEEEEEECCCEE
VVCSTGIGGPSTSIAVEELAQLGVRTFLRVGTTGAIQPHVNVGDVIVTQASVRLDGASLH
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEECCCEEE
FAPMEYPAVANFECTTAMVAASREAGLEPHIGITASSDTFYPGQERYDTVSGRITRQFKG
ECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHC
SMQEWQDLGVLNYEMESSTLFTMCSSQGWRAACVAGVIVNRTQQEIPDEATMKKTEVSAV
CHHHHHHCCCEEEEECCCEEEEECCCCCCHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHH
SIVVAAAKKLLA
HHHHHHHHHHCC
>Mature Secondary Structure 
SDVFHLGLTKEMLDGASLAIVPGDPERVKRIAELMENATFLASHREYTSYLAYIDGKPV
CCEEECCCCHHHHCCCCEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHEEEEEECCCEE
VVCSTGIGGPSTSIAVEELAQLGVRTFLRVGTTGAIQPHVNVGDVIVTQASVRLDGASLH
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEECCCEEE
FAPMEYPAVANFECTTAMVAASREAGLEPHIGITASSDTFYPGQERYDTVSGRITRQFKG
ECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHC
SMQEWQDLGVLNYEMESSTLFTMCSSQGWRAACVAGVIVNRTQQEIPDEATMKKTEVSAV
CHHHHHHCCCEEEEECCCEEEEECCCCCCHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHH
SIVVAAAKKLLA
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2674901; 1379743; 9278503; 8506346; 8899705; 9661793; 7796917; 12499542 [H]