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The map label for this gene is coaE [H]

Identifier: 167622407

GI number: 167622407

Start: 553825

End: 554430

Strand: Reverse

Name: coaE [H]

Synonym: Shal_0467

Alternate gene names: 167622407

Gene position: 554430-553825 (Counterclockwise)

Preceding gene: 167622408

Following gene: 167622406

Centisome position: 10.61

GC content: 41.42

Gene sequence:

>606_bases
ATGGCTGACTATATAGTTGGACTAACAGGTGGCATTGGTAGCGGTAAAACCACCGTTGCCAACCTTTTTGCAAGACTTGG
CATCACTCTGGTTGATGCCGATATCATCTCCCGCGATGTGGTAGCTAAAGGCTCTACAGGCCTTAGTGAGATTGTTAAGC
ACTTCGGTAATACTGTTCTATTGAGTGACGGCAATTTAAATCGCTCAATGCTAAGGGAAAAGATTTTTGAGGAAGATAGC
GAGCGTGTCTGGCTAAACAATCTATTACACCCGATGATTAGAGAAACCATGCTTCAACAGTGCAAACAAGCACAATCAAG
CTATGTAATTATGATTGTGCCCTTGCTATTTGAGAACGGGTTAGATAGTTTAGTAGATCGAACGCTCTTGGTGGATATTT
CGCCGGACCTGCAGCAACAAAGAACCATAAGCAGAGATACCGTTAGCGCTCAACAAGTTAAAAATATAATAGGCAGTCAG
GCTTCAAGAGCTGAGAAACTGTCAAAAGCTGATGATGTCATAGACAATCAAGGAGAGATATCGGCGTTAAAGTGCAAGGT
AGAAGCACTACATAACTTTTATTTAAAATTATCCAGTAATTCTTGA

Upstream 100 bases:

>100_bases
ATCGCAGCCGCAGGCTGGATTGCCATGATCTGGGGTGAGAGTATTACCAATTGGTACCTGTCTACCCTATAAAGGCCATT
TAAGGAATTAAGGAACAGCG

Downstream 100 bases:

>100_bases
ATAACGCCATGACTGAATTGATCTATGAACAGCCTTTGAACGAAAAAACTCGTAGCTACCTGCGCCTAGAATACTTGGCA
CAACAGCTACAGGCTAACCT

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MADYIVGLTGGIGSGKTTVANLFARLGITLVDADIISRDVVAKGSTGLSEIVKHFGNTVLLSDGNLNRSMLREKIFEEDS
ERVWLNNLLHPMIRETMLQQCKQAQSSYVIMIVPLLFENGLDSLVDRTLLVDISPDLQQQRTISRDTVSAQQVKNIIGSQ
ASRAEKLSKADDVIDNQGEISALKCKVEALHNFYLKLSSNS

Sequences:

>Translated_201_residues
MADYIVGLTGGIGSGKTTVANLFARLGITLVDADIISRDVVAKGSTGLSEIVKHFGNTVLLSDGNLNRSMLREKIFEEDS
ERVWLNNLLHPMIRETMLQQCKQAQSSYVIMIVPLLFENGLDSLVDRTLLVDISPDLQQQRTISRDTVSAQQVKNIIGSQ
ASRAEKLSKADDVIDNQGEISALKCKVEALHNFYLKLSSNS
>Mature_200_residues
ADYIVGLTGGIGSGKTTVANLFARLGITLVDADIISRDVVAKGSTGLSEIVKHFGNTVLLSDGNLNRSMLREKIFEEDSE
RVWLNNLLHPMIRETMLQQCKQAQSSYVIMIVPLLFENGLDSLVDRTLLVDISPDLQQQRTISRDTVSAQQVKNIIGSQA
SRAEKLSKADDVIDNQGEISALKCKVEALHNFYLKLSSNS

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=193, Percent_Identity=36.2694300518135, Blast_Score=120, Evalue=5e-28,
Organism=Homo sapiens, GI191252795, Length=193, Percent_Identity=36.2694300518135, Blast_Score=120, Evalue=5e-28,
Organism=Homo sapiens, GI110227605, Length=189, Percent_Identity=26.984126984127, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI110227603, Length=189, Percent_Identity=26.984126984127, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI110227601, Length=189, Percent_Identity=26.984126984127, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI110227607, Length=189, Percent_Identity=26.984126984127, Blast_Score=71, Evalue=5e-13,
Organism=Homo sapiens, GI205277394, Length=189, Percent_Identity=26.984126984127, Blast_Score=71, Evalue=5e-13,
Organism=Escherichia coli, GI1786292, Length=196, Percent_Identity=51.0204081632653, Blast_Score=202, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI17554944, Length=189, Percent_Identity=33.8624338624339, Blast_Score=114, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI25143409, Length=167, Percent_Identity=26.9461077844311, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6320402, Length=194, Percent_Identity=34.020618556701, Blast_Score=107, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24644728, Length=193, Percent_Identity=34.1968911917098, Blast_Score=120, Evalue=7e-28,
Organism=Drosophila melanogaster, GI24658602, Length=181, Percent_Identity=25.9668508287293, Blast_Score=80, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977
- InterPro:   IPR000764 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22107; Mature: 21975

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADYIVGLTGGIGSGKTTVANLFARLGITLVDADIISRDVVAKGSTGLSEIVKHFGNTVL
CCCEEEEECCCCCCCHHHHHHHHHHHCHHHEHHHHHHHHHHCCCCCCHHHHHHHHCCEEE
LSDGNLNRSMLREKIFEEDSERVWLNNLLHPMIRETMLQQCKQAQSSYVIMIVPLLFENG
EECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHCC
LDSLVDRTLLVDISPDLQQQRTISRDTVSAQQVKNIIGSQASRAEKLSKADDVIDNQGEI
HHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCH
SALKCKVEALHNFYLKLSSNS
HHHHHHHHHHHHHHHEECCCC
>Mature Secondary Structure 
ADYIVGLTGGIGSGKTTVANLFARLGITLVDADIISRDVVAKGSTGLSEIVKHFGNTVL
CCEEEEECCCCCCCHHHHHHHHHHHCHHHEHHHHHHHHHHCCCCCCHHHHHHHHCCEEE
LSDGNLNRSMLREKIFEEDSERVWLNNLLHPMIRETMLQQCKQAQSSYVIMIVPLLFENG
EECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHCC
LDSLVDRTLLVDISPDLQQQRTISRDTVSAQQVKNIIGSQASRAEKLSKADDVIDNQGEI
HHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCH
SALKCKVEALHNFYLKLSSNS
HHHHHHHHHHHHHHHEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]