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The map label for this gene is rnpA

Identifier: 167041023

GI number: 167041023

Start: 2456423

End: 2456773

Strand: Reverse

Name: rnpA

Synonym: Teth514_2413

Alternate gene names: 167041023

Gene position: 2456773-2456423 (Counterclockwise)

Preceding gene: 167041024

Following gene: 167041022

Centisome position: 99.98

GC content: 26.5

Gene sequence:

>351_bases
ATGAGGAGAAAGATTGTAAAAATTAAAAAAAGTTATGAATTTAAAAAGGTTTATTCAAATGGAAAATCTGTTGCTAATCA
GTTTGTTGTAATGTATTATATGGAAAATAATTTAGGTTTTAATAGAGTTGGCTATTCAGTGAGTAAAAAAATAGGTAAAA
GTGTGGTAAGAAATAGAGTTAGAAGGCTTTTACATGAAAGTTTTAGACTTTTAGATATTGAGATAAAAACAGGTTTTGAT
ATAATTTTTGTCGCAAGAGGAAAAATTGTAGAGGCTGATTTTCACACTTTAAAAAATTCCATGAGAAAATTAATTATGAA
AACACCTCTTTATGCGGGGAATGAAAAATGA

Upstream 100 bases:

>100_bases
CAAAAGCGGTCGCAATGTTTTAAAAAGAAGAAGACAAAAAGGTAGACATAGATTGACAGCGTGAGGCCTTTAGGGCCTTT
TTTACAATCCGGAGGTATAA

Downstream 100 bases:

>100_bases
AAAATGTTGTTATTTTTTTAATTAAGTTGTATCAAAGATATATTTCGCCTATGAAGCCAAGGAGCTGTAGATTTTACCCA
ACTTGTTCTCAATATTCTAT

Product: ribonuclease P

Products: NA

Alternate protein names: RNase P protein; RNaseP protein; Protein C5

Number of amino acids: Translated: 116; Mature: 116

Protein sequence:

>116_residues
MRRKIVKIKKSYEFKKVYSNGKSVANQFVVMYYMENNLGFNRVGYSVSKKIGKSVVRNRVRRLLHESFRLLDIEIKTGFD
IIFVARGKIVEADFHTLKNSMRKLIMKTPLYAGNEK

Sequences:

>Translated_116_residues
MRRKIVKIKKSYEFKKVYSNGKSVANQFVVMYYMENNLGFNRVGYSVSKKIGKSVVRNRVRRLLHESFRLLDIEIKTGFD
IIFVARGKIVEADFHTLKNSMRKLIMKTPLYAGNEK
>Mature_116_residues
MRRKIVKIKKSYEFKKVYSNGKSVANQFVVMYYMENNLGFNRVGYSVSKKIGKSVVRNRVRRLLHESFRLLDIEIKTGFD
IIFVARGKIVEADFHTLKNSMRKLIMKTPLYAGNEK

Specific function: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-lead

COG id: COG0594

COG function: function code J; RNase P protein component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rnpA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNPA_THEP3 (B0K8I3)

Other databases:

- EMBL:   CP000924
- RefSeq:   YP_001666251.1
- ProteinModelPortal:   B0K8I3
- SMR:   B0K8I3
- GeneID:   5873527
- GenomeReviews:   CP000924_GR
- KEGG:   tpd:Teth39_2294
- HOGENOM:   HBG728160
- OMA:   CAEMERV
- ProtClustDB:   PRK00499
- BioCyc:   TPSE340099:TETH39_2294-MONOMER
- HAMAP:   MF_00227
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR000100
- Gene3D:   G3DSA:3.30.230.10
- ProDom:   PD003629
- TIGRFAMs:   TIGR00188

Pfam domain/function: PF00825 Ribonuclease_P; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: =3.1.26.5

Molecular weight: Translated: 13625; Mature: 13625

Theoretical pI: Translated: 11.05; Mature: 11.05

Prosite motif: PS00648 RIBONUCLEASE_P

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRKIVKIKKSYEFKKVYSNGKSVANQFVVMYYMENNLGFNRVGYSVSKKIGKSVVRNRV
CCCHHHHHHHHHHHHHHHCCCHHHHHHEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
RRLLHESFRLLDIEIKTGFDIIFVARGKIVEADFHTLKNSMRKLIMKTPLYAGNEK
HHHHHHHHHEEEEEECCCCEEEEEECCCEEEHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MRRKIVKIKKSYEFKKVYSNGKSVANQFVVMYYMENNLGFNRVGYSVSKKIGKSVVRNRV
CCCHHHHHHHHHHHHHHHCCCHHHHHHEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
RRLLHESFRLLDIEIKTGFDIIFVARGKIVEADFHTLKNSMRKLIMKTPLYAGNEK
HHHHHHHHHEEEEEECCCCEEEEEECCCEEEHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA