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The map label for this gene is dnaC [H]

Identifier: 167040998

GI number: 167040998

Start: 2432201

End: 2433529

Strand: Reverse

Name: dnaC [H]

Synonym: Teth514_2387

Alternate gene names: 167040998

Gene position: 2433529-2432201 (Counterclockwise)

Preceding gene: 167040999

Following gene: 167040997

Centisome position: 99.03

GC content: 38.75

Gene sequence:

>1329_bases
ATGGAGTGGAGCAAAATCCCTCCACAAAACATAGAAGCTGAACAATCCGTCTTAGGGTCAATGCTTTTATCTAGAGATGC
TATAATAGATGTGTCTGAAATAATAAAAGCTGATGACTTTTATAAAGAATCCCACAAAAAATTATTTGACGTAATGATGG
AGATGTTTGAAAAAGACATCCCCGTTGACCTTGTGACAGTGGTTGATGAACTCAGAAAGCGCAACATGCTGGAGGCTGTT
GGCGGAATCGATTATATAGCAAGTTTGTCTTCCAATGTCATCACCACTGCTAATGTATCTTACTATGCAAAGCTAATAAA
GGAAAAAGCTACATTGAGAAGACTCATTGAGGCTTCTTCAGAGATTATGGAGTTAAGTTACGAAGGGGATGATGTAGAGA
CTGTCCTTGACATAGCAGAACAAAAAATATTTGATATAGCTCAAGGAAGAAACACTACTAATTTTTCACCTATAAAAGAT
GTCTTAATGAATACATTTTATAAAATAGAAGAACTTTACAAAAACAAAGGCCAGCTTACGGGAATTCCCTCTGGCTTTCC
TGACCTTGACTTAAAAACTGCTGGCTTTCAGCCCTCTGACTTTATATTAGTCGCAGCAAGACCTTCAATGGGAAAAACCT
CTTTTGCTTTAAATATTGCTCAAAATGCAGCTCTTTTGACAGGCCTTCCTGTTGCCATATTTAGCTTAGAGATGTCAAAA
GAGCAGTTGGTAAACAGGCTTATCTGTTCTACTGCCAATATAGATAGCCAAAAGCTTAGGACAGGAAACCTTGATGAAGA
TGACTGGATGAAACTGGCAGCCGCGATGACTCCTCTTTCTAAAGCTCCTATCTATATTGATGATACCCCTGGAATTGGCG
TAATGGACATAAGGGCGAAGTGCCGGCGCCTTAAACTAGAAAAAGGATTGGGCTTGGTGATGATAGATTATCTGCAGCTT
ATGCAGGGAAGAGGAAGGGCAGAAAACAGGCAACAAGAAATTTCAGAAATATCGAGGTCTCTTAAAAGTTTAGCAAGAGA
ACTCAATGTTCCTGTAATTACCCTTTCACAGTTGTCTCGCGCACCTGAGTCTAGGTCAGACCACAGACCTATTTTGAGCG
ATTTGAGAGAATCTGGAGCAATAGAGCAGGACGCTGACATAGTAATGTTTTTGTACAGAGATGATTACTATCATAAAGAT
TCTGAAAAGAAAAACATAGCAGAAGTTATAATTGCAAAACACAGAAATGGACCCACAGGTACAGTGGAACTTTTGTGGCT
TGCACAGTATACAAAATTTGTAAGTCTTGATAAATATAGAATGGAATAA

Upstream 100 bases:

>100_bases
ACAGGGACATATTATGTAGACATAAAACTTTATCAAGGGGTTACTGCAAAAGTGAAGGTAGATGTTGTGGCAGAGTAATT
TAAATCAAGGGGGAATAAGG

Downstream 100 bases:

>100_bases
TCTTTAGTTTACTCTTATGAAGGGATGAAAGTTATTATGGGCAATTTCGATTATCTTAAAAAAGTCCCTTATTTTAATGA
ACTGGAGGACAAATCCCTTG

Product: replicative DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MEWSKIPPQNIEAEQSVLGSMLLSRDAIIDVSEIIKADDFYKESHKKLFDVMMEMFEKDIPVDLVTVVDELRKRNMLEAV
GGIDYIASLSSNVITTANVSYYAKLIKEKATLRRLIEASSEIMELSYEGDDVETVLDIAEQKIFDIAQGRNTTNFSPIKD
VLMNTFYKIEELYKNKGQLTGIPSGFPDLDLKTAGFQPSDFILVAARPSMGKTSFALNIAQNAALLTGLPVAIFSLEMSK
EQLVNRLICSTANIDSQKLRTGNLDEDDWMKLAAAMTPLSKAPIYIDDTPGIGVMDIRAKCRRLKLEKGLGLVMIDYLQL
MQGRGRAENRQQEISEISRSLKSLARELNVPVITLSQLSRAPESRSDHRPILSDLRESGAIEQDADIVMFLYRDDYYHKD
SEKKNIAEVIIAKHRNGPTGTVELLWLAQYTKFVSLDKYRME

Sequences:

>Translated_442_residues
MEWSKIPPQNIEAEQSVLGSMLLSRDAIIDVSEIIKADDFYKESHKKLFDVMMEMFEKDIPVDLVTVVDELRKRNMLEAV
GGIDYIASLSSNVITTANVSYYAKLIKEKATLRRLIEASSEIMELSYEGDDVETVLDIAEQKIFDIAQGRNTTNFSPIKD
VLMNTFYKIEELYKNKGQLTGIPSGFPDLDLKTAGFQPSDFILVAARPSMGKTSFALNIAQNAALLTGLPVAIFSLEMSK
EQLVNRLICSTANIDSQKLRTGNLDEDDWMKLAAAMTPLSKAPIYIDDTPGIGVMDIRAKCRRLKLEKGLGLVMIDYLQL
MQGRGRAENRQQEISEISRSLKSLARELNVPVITLSQLSRAPESRSDHRPILSDLRESGAIEQDADIVMFLYRDDYYHKD
SEKKNIAEVIIAKHRNGPTGTVELLWLAQYTKFVSLDKYRME
>Mature_442_residues
MEWSKIPPQNIEAEQSVLGSMLLSRDAIIDVSEIIKADDFYKESHKKLFDVMMEMFEKDIPVDLVTVVDELRKRNMLEAV
GGIDYIASLSSNVITTANVSYYAKLIKEKATLRRLIEASSEIMELSYEGDDVETVLDIAEQKIFDIAQGRNTTNFSPIKD
VLMNTFYKIEELYKNKGQLTGIPSGFPDLDLKTAGFQPSDFILVAARPSMGKTSFALNIAQNAALLTGLPVAIFSLEMSK
EQLVNRLICSTANIDSQKLRTGNLDEDDWMKLAAAMTPLSKAPIYIDDTPGIGVMDIRAKCRRLKLEKGLGLVMIDYLQL
MQGRGRAENRQQEISEISRSLKSLARELNVPVITLSQLSRAPESRSDHRPILSDLRESGAIEQDADIVMFLYRDDYYHKD
SEKKNIAEVIIAKHRNGPTGTVELLWLAQYTKFVSLDKYRME

Specific function: Participates In Initiation And Elongation During Chromosome Replication; It Exhibits DNA-Dependent ATPase Activity And Contains Distinct Active Sites For ATP Binding, DNA Binding, And Interaction With DNAc Protein, Primase, And Other Prepriming Proteins.

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=436, Percent_Identity=48.8532110091743, Blast_Score=431, Evalue=1e-122,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 49809; Mature: 49809

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWSKIPPQNIEAEQSVLGSMLLSRDAIIDVSEIIKADDFYKESHKKLFDVMMEMFEKDI
CCCCCCCCCCCCHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PVDLVTVVDELRKRNMLEAVGGIDYIASLSSNVITTANVSYYAKLIKEKATLRRLIEASS
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHHH
EIMELSYEGDDVETVLDIAEQKIFDIAQGRNTTNFSPIKDVLMNTFYKIEELYKNKGQLT
HHHEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
GIPSGFPDLDLKTAGFQPSDFILVAARPSMGKTSFALNIAQNAALLTGLPVAIFSLEMSK
CCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEHHHCCHHHHCCHHHHHHHHCCH
EQLVNRLICSTANIDSQKLRTGNLDEDDWMKLAAAMTPLSKAPIYIDDTPGIGVMDIRAK
HHHHHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHH
CRRLKLEKGLGLVMIDYLQLMQGRGRAENRQQEISEISRSLKSLARELNVPVITLSQLSR
HHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHC
APESRSDHRPILSDLRESGAIEQDADIVMFLYRDDYYHKDSEKKNIAEVIIAKHRNGPTG
CCCCCCCCCHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCC
TVELLWLAQYTKFVSLDKYRME
HHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEWSKIPPQNIEAEQSVLGSMLLSRDAIIDVSEIIKADDFYKESHKKLFDVMMEMFEKDI
CCCCCCCCCCCCHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PVDLVTVVDELRKRNMLEAVGGIDYIASLSSNVITTANVSYYAKLIKEKATLRRLIEASS
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHHH
EIMELSYEGDDVETVLDIAEQKIFDIAQGRNTTNFSPIKDVLMNTFYKIEELYKNKGQLT
HHHEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
GIPSGFPDLDLKTAGFQPSDFILVAARPSMGKTSFALNIAQNAALLTGLPVAIFSLEMSK
CCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEHHHCCHHHHCCHHHHHHHHCCH
EQLVNRLICSTANIDSQKLRTGNLDEDDWMKLAAAMTPLSKAPIYIDDTPGIGVMDIRAK
HHHHHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHH
CRRLKLEKGLGLVMIDYLQLMQGRGRAENRQQEISEISRSLKSLARELNVPVITLSQLSR
HHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHC
APESRSDHRPILSDLRESGAIEQDADIVMFLYRDDYYHKDSEKKNIAEVIIAKHRNGPTG
CCCCCCCCCHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCC
TVELLWLAQYTKFVSLDKYRME
HHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1312531 [H]