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The map label for this gene is fnr [H]

Identifier: 167040997

GI number: 167040997

Start: 2431487

End: 2432164

Strand: Reverse

Name: fnr [H]

Synonym: Teth514_2386

Alternate gene names: 167040997

Gene position: 2432164-2431487 (Counterclockwise)

Preceding gene: 167040998

Following gene: 167040995

Centisome position: 98.98

GC content: 33.78

Gene sequence:

>678_bases
ATGGGCAATTTCGATTATCTTAAAAAAGTCCCTTATTTTAATGAACTGGAGGACAAATCCCTTGAAGAGATACATAAGAT
TTTAATCATAAAATCTTTTAAAAAAGGCTCTATTATTTTCATGGAGGGGGAAAAGGGAGAAGCCATATATTTTGTAAAAT
CCGGCAAAGTTAAAATATCAAAAACCTCTTCTGTCGGGAAAGAACACATTATTAAAATCATGGAAGAAGGGGACATATTT
GCTGAATCTGTTCTATTTGTCGGTGGAGAATATCCTGCAACTGCAGAGGCTATAGAGGACTCCGAAGTGATTATGCTTAA
AAACCAAGACATAGAAAACTTGATACTAAAAAACAGCAAAATAGCCTTAAGCATTATTAAACTTATGGCAAAAAGGCTAA
AAAATGTAGCTGTCATAATAGAAAATCTTGCTTTAAGAGATTCCATTGGCAGAACGGCTTCTGTCCTTCTCACTTTTGCA
AAAGAGAGAGGAATAAACACAAAAGAAGGAATTTTATTAAACTTAAATCTCAATAGACAAGACCTTGCCAACATAGTCGG
CACATCAAGAGAAAACGTCACAAGGATTTTAAGCCAAATGGACAAAGAGGGGATAATACATCTTGATAGGCAGAAAATAA
TAATTAAAGATATAGAAAGGCTTAAAGAGATGTTGTAG

Upstream 100 bases:

>100_bases
GGAACTTTTGTGGCTTGCACAGTATACAAAATTTGTAAGTCTTGATAAATATAGAATGGAATAATCTTTAGTTTACTCTT
ATGAAGGGATGAAAGTTATT

Downstream 100 bases:

>100_bases
TGATATTTTTCCTTCCAATCACTAAAAAAATAACCTACAGGCACTTCAAGTTTTTCAGCTATATAAATAAGTTGCTCTAA
AGAAGGCAATGTTTTGCCAT

Product: CRP/FNR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MGNFDYLKKVPYFNELEDKSLEEIHKILIIKSFKKGSIIFMEGEKGEAIYFVKSGKVKISKTSSVGKEHIIKIMEEGDIF
AESVLFVGGEYPATAEAIEDSEVIMLKNQDIENLILKNSKIALSIIKLMAKRLKNVAVIIENLALRDSIGRTASVLLTFA
KERGINTKEGILLNLNLNRQDLANIVGTSRENVTRILSQMDKEGIIHLDRQKIIIKDIERLKEML

Sequences:

>Translated_225_residues
MGNFDYLKKVPYFNELEDKSLEEIHKILIIKSFKKGSIIFMEGEKGEAIYFVKSGKVKISKTSSVGKEHIIKIMEEGDIF
AESVLFVGGEYPATAEAIEDSEVIMLKNQDIENLILKNSKIALSIIKLMAKRLKNVAVIIENLALRDSIGRTASVLLTFA
KERGINTKEGILLNLNLNRQDLANIVGTSRENVTRILSQMDKEGIIHLDRQKIIIKDIERLKEML
>Mature_224_residues
GNFDYLKKVPYFNELEDKSLEEIHKILIIKSFKKGSIIFMEGEKGEAIYFVKSGKVKISKTSSVGKEHIIKIMEEGDIFA
ESVLFVGGEYPATAEAIEDSEVIMLKNQDIENLILKNSKIALSIIKLMAKRLKNVAVIIENLALRDSIGRTASVLLTFAK
ERGINTKEGILLNLNLNRQDLANIVGTSRENVTRILSQMDKEGIIHLDRQKIIIKDIERLKEML

Specific function: It is involved in the activation of genes necessary for anaerobic respiration [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789756, Length=200, Percent_Identity=30.5, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1787595, Length=219, Percent_Identity=24.2009132420091, Blast_Score=70, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 25419; Mature: 25288

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNFDYLKKVPYFNELEDKSLEEIHKILIIKSFKKGSIIFMEGEKGEAIYFVKSGKVKIS
CCCHHHHHHCCCCCCCCHHHHHHHHHHHHHEECCCCCEEEEECCCCCEEEEEECCEEEEE
KTSSVGKEHIIKIMEEGDIFAESVLFVGGEYPATAEAIEDSEVIMLKNQDIENLILKNSK
CCHHCCHHHHHHHHHCCCHHHHHHEEECCCCCCHHHHCCCCCEEEEECCCHHHHHHCCCH
IALSIIKLMAKRLKNVAVIIENLALRDSIGRTASVLLTFAKERGINTKEGILLNLNLNRQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEEEEEECCHH
DLANIVGTSRENVTRILSQMDKEGIIHLDRQKIIIKDIERLKEML
HHHHHHCCCHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHC
>Mature Secondary Structure 
GNFDYLKKVPYFNELEDKSLEEIHKILIIKSFKKGSIIFMEGEKGEAIYFVKSGKVKIS
CCHHHHHHCCCCCCCCHHHHHHHHHHHHHEECCCCCEEEEECCCCCEEEEEECCEEEEE
KTSSVGKEHIIKIMEEGDIFAESVLFVGGEYPATAEAIEDSEVIMLKNQDIENLILKNSK
CCHHCCHHHHHHHHHCCCHHHHHHEEECCCCCCHHHHCCCCCEEEEECCCHHHHHHCCCH
IALSIIKLMAKRLKNVAVIIENLALRDSIGRTASVLLTFAKERGINTKEGILLNLNLNRQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEEEEEECCHH
DLANIVGTSRENVTRILSQMDKEGIIHLDRQKIIIKDIERLKEML
HHHHHHCCCHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8846791; 9384377 [H]