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The map label for this gene is tig

Identifier: 167040916

GI number: 167040916

Start: 2314864

End: 2316162

Strand: Reverse

Name: tig

Synonym: Teth514_2302

Alternate gene names: 167040916

Gene position: 2316162-2314864 (Counterclockwise)

Preceding gene: 167040917

Following gene: 167040915

Centisome position: 94.26

GC content: 31.95

Gene sequence:

>1299_bases
ATGGGTGTGAGTCTTAAAAAATTAGAGAAAAGTGTTGCGACGATTGAACTTACAATACCGAGTGAAAAATTTGAAGAGGG
TTTAAATTTTGCTTTTAAAAAGAATGCATCTAAATTTAATGTACCCGGCTTTAGAAGAGGAAAGGCTCCGAGAGTAATTG
TAGAAAGATATTATGGTGAAGGAGTCCTTTATGAAGATGCTGTAGAGTATGTTTTTGATGAGGCGTATAAGGAAGCTCTT
AAAACGTTTAATTTAGAACCTGTTGATTACCCAGATATTAACATTTTACAAATTGGGAAAGGGAAAGATTTGATTTTAGA
GGCAACAGTACCTGTAATGCCTGAAGTAGAATTAGGTGAATATAAAGGCATAGAAATTGAAAAAATAGAGTATAATGTGT
ACGATGGGGATGTAGAATACGAATTAGAAAAATTAAGACAGCAAAATGCGAGGATTGTGCCTGTAGAAGGAAGACCGGCT
GAGAGCGGAGATATTGCTGTAATAGATTTTGAAGGATTTATTGATGGTAAGCCTTTTGAAGGCGGTAAAGCTGAAAATTA
TGAATTAGAATTAGGTAGCAATACTTTTATTCCCGGGTTTGAGGACCAAATAATAGGCCACAATGTAAATGAGACTTTTG
ATGTAAATATTACTTTTCCTGAAGATTATAGAGTAGAAGAATTAAGAGGCAAATCAGCTGTTTTTAAAGTCACTCTTAAG
GCTTTAAATAAAAAAGAACTGCCAGAGTTAGACGATGAATTTGCAAAAGATGTAAGTGAATTTGAAACGTTAGATGAATT
AAAAGCTGATATAAGGAAGAAATTAGAAGAAAAAAATAGGGTAGAAGCAGAAAATGAAATGAAAGAGAAAGCAGTAATGA
AAGTTGTAGAAAACGCAAAAGTTGATATACCAGATGTTATGGTGGAAAGGCAAATAGATATTTCTTTGAGGGATTTAGAT
TATAATTTGAGATATCAAGGTTTAGATTTAAATAGCTATTTATCAATTACAGGGAAGACTTTAGAAAATTTAAGAAAAGA
GATGTGGGATGGAGCTTTAAATAGAGTAAAAACTCAACTTGTCATAGACAAAATTGCCAAAGTGGAAAATATTGAAGTTA
CAGAGGAAGAATTAGAAAATAAATTAAAAGAGATGGCAGCGAATTACAGAATAAATTTGGAAGAATTCAAGAAAAGTCTT
ACTGAAAGCCAGATAAACAGCATAAAAGAGGATATAGCTTATTATAAGACGATTGACTTTATTTTCAGTAAGTGTAAAAT
AATAAGTAAAGAGGAGTGA

Upstream 100 bases:

>100_bases
AATTACAACAACTTGAGTTTGATTCACCGTTTTTTTATGTTATAATATTATAAGTTTAGAAGACTTTATACGAAAGAAAG
AGAATAGGAGGATTTGCTTA

Downstream 100 bases:

>100_bases
TTATTATGAGTCTTGTACCTATTGTTGTAGAGCAGACAAATAGAGGCGAACGTTCTTACGACATATTTTCACGTTTGCTA
AAAGACAGGATTGTCTTTTT

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MGVSLKKLEKSVATIELTIPSEKFEEGLNFAFKKNASKFNVPGFRRGKAPRVIVERYYGEGVLYEDAVEYVFDEAYKEAL
KTFNLEPVDYPDINILQIGKGKDLILEATVPVMPEVELGEYKGIEIEKIEYNVYDGDVEYELEKLRQQNARIVPVEGRPA
ESGDIAVIDFEGFIDGKPFEGGKAENYELELGSNTFIPGFEDQIIGHNVNETFDVNITFPEDYRVEELRGKSAVFKVTLK
ALNKKELPELDDEFAKDVSEFETLDELKADIRKKLEEKNRVEAENEMKEKAVMKVVENAKVDIPDVMVERQIDISLRDLD
YNLRYQGLDLNSYLSITGKTLENLRKEMWDGALNRVKTQLVIDKIAKVENIEVTEEELENKLKEMAANYRINLEEFKKSL
TESQINSIKEDIAYYKTIDFIFSKCKIISKEE

Sequences:

>Translated_432_residues
MGVSLKKLEKSVATIELTIPSEKFEEGLNFAFKKNASKFNVPGFRRGKAPRVIVERYYGEGVLYEDAVEYVFDEAYKEAL
KTFNLEPVDYPDINILQIGKGKDLILEATVPVMPEVELGEYKGIEIEKIEYNVYDGDVEYELEKLRQQNARIVPVEGRPA
ESGDIAVIDFEGFIDGKPFEGGKAENYELELGSNTFIPGFEDQIIGHNVNETFDVNITFPEDYRVEELRGKSAVFKVTLK
ALNKKELPELDDEFAKDVSEFETLDELKADIRKKLEEKNRVEAENEMKEKAVMKVVENAKVDIPDVMVERQIDISLRDLD
YNLRYQGLDLNSYLSITGKTLENLRKEMWDGALNRVKTQLVIDKIAKVENIEVTEEELENKLKEMAANYRINLEEFKKSL
TESQINSIKEDIAYYKTIDFIFSKCKIISKEE
>Mature_431_residues
GVSLKKLEKSVATIELTIPSEKFEEGLNFAFKKNASKFNVPGFRRGKAPRVIVERYYGEGVLYEDAVEYVFDEAYKEALK
TFNLEPVDYPDINILQIGKGKDLILEATVPVMPEVELGEYKGIEIEKIEYNVYDGDVEYELEKLRQQNARIVPVEGRPAE
SGDIAVIDFEGFIDGKPFEGGKAENYELELGSNTFIPGFEDQIIGHNVNETFDVNITFPEDYRVEELRGKSAVFKVTLKA
LNKKELPELDDEFAKDVSEFETLDELKADIRKKLEEKNRVEAENEMKEKAVMKVVENAKVDIPDVMVERQIDISLRDLDY
NLRYQGLDLNSYLSITGKTLENLRKEMWDGALNRVKTQLVIDKIAKVENIEVTEEELENKLKEMAANYRINLEEFKKSLT
ESQINSIKEDIAYYKTIDFIFSKCKIISKEE

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain

Homologues:

Organism=Escherichia coli, GI1786640, Length=437, Percent_Identity=30.4347826086957, Blast_Score=183, Evalue=2e-47,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): TIG_THEP3 (B0KBA5)

Other databases:

- EMBL:   CP000924
- RefSeq:   YP_001665629.1
- ProteinModelPortal:   B0KBA5
- GeneID:   5874690
- GenomeReviews:   CP000924_GR
- KEGG:   tpd:Teth39_1652
- HOGENOM:   HBG635105
- OMA:   RFIPGFE
- ProtClustDB:   PRK01490
- BioCyc:   TPSE340099:TETH39_1652-MONOMER
- HAMAP:   MF_00303
- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881
- Gene3D:   G3DSA:1.10.3120.10
- Gene3D:   G3DSA:3.30.70.1050
- PIRSF:   PIRSF003095
- TIGRFAMs:   TIGR00115

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N; SSF109998 Trigger_fac_C_bac; SSF102735 Trigger_fac_ribosome-bd_bac

EC number: NA

Molecular weight: Translated: 49651; Mature: 49520

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVSLKKLEKSVATIELTIPSEKFEEGLNFAFKKNASKFNVPGFRRGKAPRVIVERYYGE
CCCCHHHHHCCCEEEEEEECHHHHHHCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHCCC
GVLYEDAVEYVFDEAYKEALKTFNLEPVDYPDINILQIGKGKDLILEATVPVMPEVELGE
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCEEEEECCCCCCCCCCCC
YKGIEIEKIEYNVYDGDVEYELEKLRQQNARIVPVEGRPAESGDIAVIDFEGFIDGKPFE
CCCCEEEEEEEEEECCCHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCC
GGKAENYELELGSNTFIPGFEDQIIGHNVNETFDVNITFPEDYRVEELRGKSAVFKVTLK
CCCCCCEEEEECCCCCCCCCCCHHCCCCCCCEEEEEEECCCCCCHHHHCCCHHHHHHHHH
ALNKKELPELDDEFAKDVSEFETLDELKADIRKKLEEKNRVEAENEMKEKAVMKVVENAK
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
VDIPDVMVERQIDISLRDLDYNLRYQGLDLNSYLSITGKTLENLRKEMWDGALNRVKTQL
CCCCHHHHHHEECEEEEECCCCEEEECCCCCHHEEECHHHHHHHHHHHHHHHHHHHHHHH
VIDKIAKVENIEVTEEELENKLKEMAANYRINLEEFKKSLTESQINSIKEDIAYYKTIDF
HHHHHHHHCCCEECHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFSKCKIISKEE
HHHHHHHCCCCC
>Mature Secondary Structure 
GVSLKKLEKSVATIELTIPSEKFEEGLNFAFKKNASKFNVPGFRRGKAPRVIVERYYGE
CCCHHHHHCCCEEEEEEECHHHHHHCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHCCC
GVLYEDAVEYVFDEAYKEALKTFNLEPVDYPDINILQIGKGKDLILEATVPVMPEVELGE
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCEEEEECCCCCCCCCCCC
YKGIEIEKIEYNVYDGDVEYELEKLRQQNARIVPVEGRPAESGDIAVIDFEGFIDGKPFE
CCCCEEEEEEEEEECCCHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCC
GGKAENYELELGSNTFIPGFEDQIIGHNVNETFDVNITFPEDYRVEELRGKSAVFKVTLK
CCCCCCEEEEECCCCCCCCCCCHHCCCCCCCEEEEEEECCCCCCHHHHCCCHHHHHHHHH
ALNKKELPELDDEFAKDVSEFETLDELKADIRKKLEEKNRVEAENEMKEKAVMKVVENAK
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
VDIPDVMVERQIDISLRDLDYNLRYQGLDLNSYLSITGKTLENLRKEMWDGALNRVKTQL
CCCCHHHHHHEECEEEEECCCCEEEECCCCCHHEEECHHHHHHHHHHHHHHHHHHHHHHH
VIDKIAKVENIEVTEEELENKLKEMAANYRINLEEFKKSLTESQINSIKEDIAYYKTIDF
HHHHHHHHCCCEECHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFSKCKIISKEE
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA