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The map label for this gene is clpX [H]

Identifier: 167040914

GI number: 167040914

Start: 2312975

End: 2314249

Strand: Reverse

Name: clpX [H]

Synonym: Teth514_2300

Alternate gene names: 167040914

Gene position: 2314249-2312975 (Counterclockwise)

Preceding gene: 167040915

Following gene: 167040913

Centisome position: 94.18

GC content: 36.94

Gene sequence:

>1275_bases
ATGGTCAAATATGATAATCAAAAACAACTAAAGTGTTCCTTTTGCGGAAAGACACAGGACCAGGTAAAGAGGCTAGTTGC
AGGGCCTGGTGTGTATATTTGTGATGAATGCATTGAACTTTGTCAAGAAATTATAAATGAAGAATTTGAAGAAGATATTG
ATATGGGAATTGGAGAACTTCCTAAGCCAAAGGAAATAAAAGAATTTCTTGACCAATATGTAATTGGGCAGGAAAAAGCT
AAAAAAGCTTTAGCTGTTGCTGTTTACAATCATTATAAGAGAATTAACAGCAGGATAAAGCCAGACGATGTAGAACTTCA
AAAGAGCAATATTTTACTTTTAGGTCCCACAGGTTCTGGTAAAACCTTATTGGCTCAGACACTGGCAAAACTTCTAAATG
TTCCTTTTGCAATAGCTGATGCTACTTCTCTAACTGAGGCTGGATATGTTGGTGAAGACGTAGAGAATATACTCTTAAAG
CTTATACAAGCAGCAGATTATGACATAGAAAAAGCTGAAAAAGGTATAATTTACATTGACGAAATAGATAAAATAGCGAG
AAAGTCAGAAAATCCCTCTATTACTCGTGACGTCTCAGGCGAAGGCGTACAACAGGCTTTGTTAAAAATTTTAGAAGGGA
CCATTGCAAATGTGCCGCCACAAGGTGGAAGAAAACATCCTCATCAAGAGTTTATACAAATTGACACAACTAATATATTG
TTTATATGTGGTGGCGCTTTTGAAGGCATAGAAAAAATAATAGAATCCCGAATAGGGAAAAAGAGCTTAGGATTTGGCGC
AGAAGTACAGAGCAGAAAAGAAAAAGACTTAAGCGAAATTTTAAGTCATATAATGCCACAGGACCTTCTTAAATTCGGTA
TGATACCCGAGTTTATAGGAAGGGTGCCAATAGTAGTTACATTAGACCCATTGAGTAAGGATGACTTAGTAAGGATTTTG
ACAGAGCCCAAAAATGCGCTGACAAAACAATACGAAAAATTGTTTGAATTAGATGGTGTAAAGCTTGAATTTGATAAGAA
AGCTTTAGGGCTCATTGCAGATATGGCTTTGGAGAGAAAGACCGGCGCAAGAGGACTGAGGGCAATCTTAGAGGAAATTA
TGTTGGATGTGATGTACGAAATACCATCCAGTGACAACATAGAAAAGTGTATAATTACAGAGGAGACGGTACTAAAGAAG
GCTCCGCCAACATTGGTTTACTCAGATGCTCAAAAAGCCAAAAAGAAAATAAAAAAGACGGAGTCTGTTTCGTAA

Upstream 100 bases:

>100_bases
GAGGGACTTTTTCATGGACGCGGAGGATGCAAAAGCGTATGGCATTATAGACGAGGTTCTCATCAGGAATAAAAGATGAT
GCCCCAAAAGAGGTGAAATT

Downstream 100 bases:

>100_bases
AAAAATAGAGAATTTTTACATCAATCCCCCTTCTCCTTCACATACTAAAATAGTGAATGGGAAGGGGGCTTGGTTATATT
GCATAAAAGAGGGTGAAGAT

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MVKYDNQKQLKCSFCGKTQDQVKRLVAGPGVYICDECIELCQEIINEEFEEDIDMGIGELPKPKEIKEFLDQYVIGQEKA
KKALAVAVYNHYKRINSRIKPDDVELQKSNILLLGPTGSGKTLLAQTLAKLLNVPFAIADATSLTEAGYVGEDVENILLK
LIQAADYDIEKAEKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTIANVPPQGGRKHPHQEFIQIDTTNIL
FICGGAFEGIEKIIESRIGKKSLGFGAEVQSRKEKDLSEILSHIMPQDLLKFGMIPEFIGRVPIVVTLDPLSKDDLVRIL
TEPKNALTKQYEKLFELDGVKLEFDKKALGLIADMALERKTGARGLRAILEEIMLDVMYEIPSSDNIEKCIITEETVLKK
APPTLVYSDAQKAKKKIKKTESVS

Sequences:

>Translated_424_residues
MVKYDNQKQLKCSFCGKTQDQVKRLVAGPGVYICDECIELCQEIINEEFEEDIDMGIGELPKPKEIKEFLDQYVIGQEKA
KKALAVAVYNHYKRINSRIKPDDVELQKSNILLLGPTGSGKTLLAQTLAKLLNVPFAIADATSLTEAGYVGEDVENILLK
LIQAADYDIEKAEKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTIANVPPQGGRKHPHQEFIQIDTTNIL
FICGGAFEGIEKIIESRIGKKSLGFGAEVQSRKEKDLSEILSHIMPQDLLKFGMIPEFIGRVPIVVTLDPLSKDDLVRIL
TEPKNALTKQYEKLFELDGVKLEFDKKALGLIADMALERKTGARGLRAILEEIMLDVMYEIPSSDNIEKCIITEETVLKK
APPTLVYSDAQKAKKKIKKTESVS
>Mature_424_residues
MVKYDNQKQLKCSFCGKTQDQVKRLVAGPGVYICDECIELCQEIINEEFEEDIDMGIGELPKPKEIKEFLDQYVIGQEKA
KKALAVAVYNHYKRINSRIKPDDVELQKSNILLLGPTGSGKTLLAQTLAKLLNVPFAIADATSLTEAGYVGEDVENILLK
LIQAADYDIEKAEKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTIANVPPQGGRKHPHQEFIQIDTTNIL
FICGGAFEGIEKIIESRIGKKSLGFGAEVQSRKEKDLSEILSHIMPQDLLKFGMIPEFIGRVPIVVTLDPLSKDDLVRIL
TEPKNALTKQYEKLFELDGVKLEFDKKALGLIADMALERKTGARGLRAILEEIMLDVMYEIPSSDNIEKCIITEETVLKK
APPTLVYSDAQKAKKKIKKTESVS

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=340, Percent_Identity=49.7058823529412, Blast_Score=320, Evalue=2e-87,
Organism=Escherichia coli, GI1786642, Length=411, Percent_Identity=62.043795620438, Blast_Score=526, Evalue=1e-151,
Organism=Escherichia coli, GI1790366, Length=213, Percent_Identity=34.2723004694836, Blast_Score=96, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI71982908, Length=312, Percent_Identity=48.0769230769231, Blast_Score=287, Evalue=7e-78,
Organism=Caenorhabditis elegans, GI71982905, Length=312, Percent_Identity=48.0769230769231, Blast_Score=286, Evalue=1e-77,
Organism=Caenorhabditis elegans, GI71988663, Length=414, Percent_Identity=39.6135265700483, Blast_Score=265, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI71988660, Length=251, Percent_Identity=42.2310756972112, Blast_Score=179, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6319704, Length=427, Percent_Identity=42.3887587822014, Blast_Score=296, Evalue=3e-81,
Organism=Drosophila melanogaster, GI24648289, Length=318, Percent_Identity=48.7421383647799, Blast_Score=306, Evalue=2e-83,
Organism=Drosophila melanogaster, GI24648291, Length=318, Percent_Identity=48.7421383647799, Blast_Score=305, Evalue=3e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 47217; Mature: 47217

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKYDNQKQLKCSFCGKTQDQVKRLVAGPGVYICDECIELCQEIINEEFEEDIDMGIGEL
CCCCCCCCCEEHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PKPKEIKEFLDQYVIGQEKAKKALAVAVYNHYKRINSRIKPDDVELQKSNILLLGPTGSG
CCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCEEEECCCCCC
KTLLAQTLAKLLNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDIEKAEKGIIYID
HHHHHHHHHHHHCCCEEECCCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCCEEEEH
EIDKIARKSENPSITRDVSGEGVQQALLKILEGTIANVPPQGGRKHPHQEFIQIDTTNIL
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHEEECCCEEE
FICGGAFEGIEKIIESRIGKKSLGFGAEVQSRKEKDLSEILSHIMPQDLLKFGMIPEFIG
EEECCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHCCCHHHHC
RVPIVVTLDPLSKDDLVRILTEPKNALTKQYEKLFELDGVKLEFDKKALGLIADMALERK
CCCEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHH
TGARGLRAILEEIMLDVMYEIPSSDNIEKCIITEETVLKKAPPTLVYSDAQKAKKKIKKT
CCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECHHHHHHCCCCCEEECCHHHHHHHHHHH
ESVS
CCCC
>Mature Secondary Structure
MVKYDNQKQLKCSFCGKTQDQVKRLVAGPGVYICDECIELCQEIINEEFEEDIDMGIGEL
CCCCCCCCCEEHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PKPKEIKEFLDQYVIGQEKAKKALAVAVYNHYKRINSRIKPDDVELQKSNILLLGPTGSG
CCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCEEEECCCCCC
KTLLAQTLAKLLNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDIEKAEKGIIYID
HHHHHHHHHHHHCCCEEECCCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCCEEEEH
EIDKIARKSENPSITRDVSGEGVQQALLKILEGTIANVPPQGGRKHPHQEFIQIDTTNIL
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHEEECCCEEE
FICGGAFEGIEKIIESRIGKKSLGFGAEVQSRKEKDLSEILSHIMPQDLLKFGMIPEFIG
EEECCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHCCCHHHHC
RVPIVVTLDPLSKDDLVRILTEPKNALTKQYEKLFELDGVKLEFDKKALGLIADMALERK
CCCEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHH
TGARGLRAILEEIMLDVMYEIPSSDNIEKCIITEETVLKKAPPTLVYSDAQKAKKKIKKT
CCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECHHHHHHCCCCCEEECCHHHHHHHHHHH
ESVS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]