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The map label for this gene is dapB [H]

Identifier: 167040808

GI number: 167040808

Start: 2184913

End: 2185668

Strand: Direct

Name: dapB [H]

Synonym: Teth514_2185

Alternate gene names: 167040808

Gene position: 2184913-2185668 (Clockwise)

Preceding gene: 167040807

Following gene: 167040809

Centisome position: 88.92

GC content: 35.98

Gene sequence:

>756_bases
ATGATTAGAATAATAATTCACGGCTGTAACGGAAAAATGGGAAAAGTCGTAGCAAAGTTAGCAGCAGAAAGTCCCGATTT
TAAAATAGTGGCAGGAGTAGATAAAAACATCTCTCCTCTTGACTTTCCTGTTTACAGCGATTTAAAAGATGTAAAAGAAG
AAGCGGATGTAGTAATTGACTTTTCATACCATGAAGCTGTACCTAATTTAGTAAAAGCCGCTCTACAAAAGAAACTTCCT
GTAGTCATTGCCACAACAGGACTCAGTGAAGAAGAATTAAATGTCATAAAAGATGCATCAAAAGAAATACCAATTTTCAA
ATCTGCAAATATGTCCCTTGGAGTAAATATACTTATAAACCTTGTAAAAGAAGCTGCAAAAATATTGCAACAAGATTTTG
ATATTGAAATAATAGAAAAACATCATAACATGAAAAAAGACGCTCCAAGTGGTACTGCGTTAATGATTGCAGATAGCATA
AACCAAGTACTAAATGACAAAAAGGAATACGTGTATGGACGCCATACTAAAACTGAACAGAGAAAACCGAATGAATTAGG
GATACATGCAGTAAGGGGCGGCACAATTGTGGGTGAACACCAAGTAATTTTTGCTGGTCACGATGAAGTAATCACCATAA
GTCACTCTGCCCAATCCCGTGAAATTTTTGGCTATGGCGCCCTACAAGCTGCAAAATTCATAATAAATCAAAAACCTGGC
TTATATACAATGGAAGACCTTGTGAAGAAAGGATGA

Upstream 100 bases:

>100_bases
TAGGACCCCTACGCCTCCCACTTGTTGAAATGAGCGATAAAAACTTAGAATATCTGAAATCTGTTCTTTCAAAATACGGT
TTATTGAAGGAGGCAAATTA

Downstream 100 bases:

>100_bases
TAATTTTGAGCACAAATGATAACTTGACAAACCCTTATGAAATTGCAAGATACATTAAAGAGGCAAAAAAGTCAACGCCC
GTTAGAGCTTACATACAAGG

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR [H]

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MIRIIIHGCNGKMGKVVAKLAAESPDFKIVAGVDKNISPLDFPVYSDLKDVKEEADVVIDFSYHEAVPNLVKAALQKKLP
VVIATTGLSEEELNVIKDASKEIPIFKSANMSLGVNILINLVKEAAKILQQDFDIEIIEKHHNMKKDAPSGTALMIADSI
NQVLNDKKEYVYGRHTKTEQRKPNELGIHAVRGGTIVGEHQVIFAGHDEVITISHSAQSREIFGYGALQAAKFIINQKPG
LYTMEDLVKKG

Sequences:

>Translated_251_residues
MIRIIIHGCNGKMGKVVAKLAAESPDFKIVAGVDKNISPLDFPVYSDLKDVKEEADVVIDFSYHEAVPNLVKAALQKKLP
VVIATTGLSEEELNVIKDASKEIPIFKSANMSLGVNILINLVKEAAKILQQDFDIEIIEKHHNMKKDAPSGTALMIADSI
NQVLNDKKEYVYGRHTKTEQRKPNELGIHAVRGGTIVGEHQVIFAGHDEVITISHSAQSREIFGYGALQAAKFIINQKPG
LYTMEDLVKKG
>Mature_251_residues
MIRIIIHGCNGKMGKVVAKLAAESPDFKIVAGVDKNISPLDFPVYSDLKDVKEEADVVIDFSYHEAVPNLVKAALQKKLP
VVIATTGLSEEELNVIKDASKEIPIFKSANMSLGVNILINLVKEAAKILQQDFDIEIIEKHHNMKKDAPSGTALMIADSI
NQVLNDKKEYVYGRHTKTEQRKPNELGIHAVRGGTIVGEHQVIFAGHDEVITISHSAQSREIFGYGALQAAKFIINQKPG
LYTMEDLVKKG

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786214, Length=263, Percent_Identity=36.5019011406844, Blast_Score=147, Evalue=5e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040 [H]

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N [H]

EC number: =1.3.1.26 [H]

Molecular weight: Translated: 27607; Mature: 27607

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRIIIHGCNGKMGKVVAKLAAESPDFKIVAGVDKNISPLDFPVYSDLKDVKEEADVVID
CEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCEEEE
FSYHEAVPNLVKAALQKKLPVVIATTGLSEEELNVIKDASKEIPIFKSANMSLGVNILIN
EHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCCCEEECCCCCCHHHHHHH
LVKEAAKILQQDFDIEIIEKHHNMKKDAPSGTALMIADSINQVLNDKKEYVYGRHTKTEQ
HHHHHHHHHHCCCCCEEHHHHCCCCCCCCCCCEEEEHHHHHHHHCCHHHHEECCCCCCCC
RKPNELGIHAVRGGTIVGEHQVIFAGHDEVITISHSAQSREIFGYGALQAAKFIINQKPG
CCCCCCCEEEEECCEEEECCEEEEECCCCEEEEECCCCCCEEEECHHHHHHHHHHCCCCC
LYTMEDLVKKG
CEEHHHHHHCC
>Mature Secondary Structure
MIRIIIHGCNGKMGKVVAKLAAESPDFKIVAGVDKNISPLDFPVYSDLKDVKEEADVVID
CEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCEEEE
FSYHEAVPNLVKAALQKKLPVVIATTGLSEEELNVIKDASKEIPIFKSANMSLGVNILIN
EHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCCCEEECCCCCCHHHHHHH
LVKEAAKILQQDFDIEIIEKHHNMKKDAPSGTALMIADSINQVLNDKKEYVYGRHTKTEQ
HHHHHHHHHHCCCCCEEHHHHCCCCCCCCCCCEEEEHHHHHHHHCCHHHHEECCCCCCCC
RKPNELGIHAVRGGTIVGEHQVIFAGHDEVITISHSAQSREIFGYGALQAAKFIINQKPG
CCCCCCCEEEEECCEEEECCEEEEECCCCEEEEECCCCCCEEEECHHHHHHHHHHCCCCC
LYTMEDLVKKG
CEEHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]