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The map label for this gene is capA [H]

Identifier: 167040501

GI number: 167040501

Start: 1885423

End: 1886601

Strand: Reverse

Name: capA [H]

Synonym: Teth514_1870

Alternate gene names: 167040501

Gene position: 1886601-1885423 (Counterclockwise)

Preceding gene: 167040502

Following gene: 167040500

Centisome position: 76.78

GC content: 31.3

Gene sequence:

>1179_bases
ATGCTTTTTAATTTGAGGAAAAAATATTTTATAATATTAGCTTTCTTGATATTCTTATTATTTTTAATGAGCGGGTGTAA
CTTTTATACAAGTACTGATATTCCTACAAAGGGAGCTTTGTCAGAAGAGAAGAAAGATATAAAAACTATTACTATAACTG
CAGTAGGAGATATAATGGTTCATATGCCACAAGCTAAAAGTGCTATAAAGCCAGATGGAAGCTATGATTTTACCCCTCAC
TTTGAGGAGGTAAGGGAGTACATAAAAGACAGTGATATAGCGATATGTAACCTTGAGACCACTATAAGTACTCCCGTAAA
GGGTTATACTGGATACCCTCGTTTTAGGTCACCAGAGGAAATTATTCCAGCAATAAAGTATACAGGTTTTAATGTAGTCA
TTACTGCTAATAATCACAGCTTAGATAATTTAGAATTTGGAGTTGTAAATACTTTAAATGCTTTGGATAAATATGGTCTA
TTTCATGCAGGCACTTATAGAAATGAGGAAGAAAGCAAAAAAATATTAATTATTGATAAAAAAGGTATAAAAGTAGCGAT
ACTTGCTTATACTTTCGGAACAAATGGTATGGAGGTTCACATTGATAGGGGTAAGTTAAAATATATGGTAAATTATATCG
AAGAAGAAAAAATTTTAAAAGATATAAATAGAGCAAAAGAAGAAGGAGCAGATATAGTAATCTTGTATTTACATTGGGGA
ATGGAGTACGCTAGAACGGTTGATGAAGAAAGGAAAACTTTAACTGATAAATTATTTAGAGCTGGTGCGGATATAATATT
GGGTACACATCCTCATGTAATACAGCCTATGGAGAAAAAGAAAATAACTACAGATGAGGGAGAAGAAAAAGAAGTTTTTG
TGGCATATTCATTGGGAAATTTTATATCTAATCAAAGAGATCGCTATCAAGATAGTGGTGTAATTGTAAATATCACTATT
ACTAAGAAAAATGATAAAACAAGTATTACTGAAGTAAGTTATGTTCCTACTTGGGTAAGAGTCTTTAAAAAAGAAGGCAA
GACACAATATAGAATATTGCCTGTAGGGAAATTTTTAAATTGTGAAGAATTATCAAGTACTGAACTTGAGCGAATTAGAG
AAGTATGGCAAGAAACAACTGACATAGTAGGTAGTGATGGGATAAAAATTAAAGACTAA

Upstream 100 bases:

>100_bases
TAAAAATTGATTATAAACCGGAAGGAGTTACAATTGACGAGAAGATAAAAAAATATGAGAATCTTTAAAAGGATGAAAAA
TTATCTTTGGAGTTGATTTG

Downstream 100 bases:

>100_bases
TTAGAACCAGCTAATTTGCATAATTATTTTTATTTTGCATAAAAATATATTGACAAATAATTTAATGCGTTATAGAATTA
AAATAACACAATTTAAATAT

Product: poly-gamma-glutamate biosynthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MLFNLRKKYFIILAFLIFLLFLMSGCNFYTSTDIPTKGALSEEKKDIKTITITAVGDIMVHMPQAKSAIKPDGSYDFTPH
FEEVREYIKDSDIAICNLETTISTPVKGYTGYPRFRSPEEIIPAIKYTGFNVVITANNHSLDNLEFGVVNTLNALDKYGL
FHAGTYRNEEESKKILIIDKKGIKVAILAYTFGTNGMEVHIDRGKLKYMVNYIEEEKILKDINRAKEEGADIVILYLHWG
MEYARTVDEERKTLTDKLFRAGADIILGTHPHVIQPMEKKKITTDEGEEKEVFVAYSLGNFISNQRDRYQDSGVIVNITI
TKKNDKTSITEVSYVPTWVRVFKKEGKTQYRILPVGKFLNCEELSSTELERIREVWQETTDIVGSDGIKIKD

Sequences:

>Translated_392_residues
MLFNLRKKYFIILAFLIFLLFLMSGCNFYTSTDIPTKGALSEEKKDIKTITITAVGDIMVHMPQAKSAIKPDGSYDFTPH
FEEVREYIKDSDIAICNLETTISTPVKGYTGYPRFRSPEEIIPAIKYTGFNVVITANNHSLDNLEFGVVNTLNALDKYGL
FHAGTYRNEEESKKILIIDKKGIKVAILAYTFGTNGMEVHIDRGKLKYMVNYIEEEKILKDINRAKEEGADIVILYLHWG
MEYARTVDEERKTLTDKLFRAGADIILGTHPHVIQPMEKKKITTDEGEEKEVFVAYSLGNFISNQRDRYQDSGVIVNITI
TKKNDKTSITEVSYVPTWVRVFKKEGKTQYRILPVGKFLNCEELSSTELERIREVWQETTDIVGSDGIKIKD
>Mature_392_residues
MLFNLRKKYFIILAFLIFLLFLMSGCNFYTSTDIPTKGALSEEKKDIKTITITAVGDIMVHMPQAKSAIKPDGSYDFTPH
FEEVREYIKDSDIAICNLETTISTPVKGYTGYPRFRSPEEIIPAIKYTGFNVVITANNHSLDNLEFGVVNTLNALDKYGL
FHAGTYRNEEESKKILIIDKKGIKVAILAYTFGTNGMEVHIDRGKLKYMVNYIEEEKILKDINRAKEEGADIVILYLHWG
MEYARTVDEERKTLTDKLFRAGADIILGTHPHVIQPMEKKKITTDEGEEKEVFVAYSLGNFISNQRDRYQDSGVIVNITI
TKKNDKTSITEVSYVPTWVRVFKKEGKTQYRILPVGKFLNCEELSSTELERIREVWQETTDIVGSDGIKIKD

Specific function: Essential for the synthesis of the polyglutamate capsule of B.anthracis which is one of the principal virulence factors during anthrax infection. May form a polyglutamyl synthetase complex together with proteins CapB and CapC [H]

COG id: COG2843

COG function: function code M; Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CapA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019079 [H]

Pfam domain/function: PF09587 PGA_cap [H]

EC number: NA

Molecular weight: Translated: 44794; Mature: 44794

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFNLRKKYFIILAFLIFLLFLMSGCNFYTSTDIPTKGALSEEKKDIKTITITAVGDIMV
CCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHCCCCEEEEEEEECEEEE
HMPQAKSAIKPDGSYDFTPHFEEVREYIKDSDIAICNLETTISTPVKGYTGYPRFRSPEE
ECCCHHCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCEECCCCCCCCCCCCCCCHHH
IIPAIKYTGFNVVITANNHSLDNLEFGVVNTLNALDKYGLFHAGTYRNEEESKKILIIDK
HHCCEEECCEEEEEEECCCCCCCEEEHHHHHHHHHHHCCCEECCCCCCCCCCCEEEEEEC
KGIKVAILAYTFGTNGMEVHIDRGKLKYMVNYIEEEKILKDINRAKEEGADIVILYLHWG
CCCEEEEEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
MEYARTVDEERKTLTDKLFRAGADIILGTHPHVIQPMEKKKITTDEGEEKEVFVAYSLGN
HHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHCCCHHHCCCCCCCCCCCEEEEEEEHHH
FISNQRDRYQDSGVIVNITITKKNDKTSITEVSYVPTWVRVFKKEGKTQYRILPVGKFLN
HHCCHHHHHCCCCEEEEEEEEECCCCCCEEEEEHHHHHHHHHHHCCCCEEEEEECCCCCC
CEELSSTELERIREVWQETTDIVGSDGIKIKD
HHHCCHHHHHHHHHHHHHHHHHCCCCCCEECC
>Mature Secondary Structure
MLFNLRKKYFIILAFLIFLLFLMSGCNFYTSTDIPTKGALSEEKKDIKTITITAVGDIMV
CCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHCCCCEEEEEEEECEEEE
HMPQAKSAIKPDGSYDFTPHFEEVREYIKDSDIAICNLETTISTPVKGYTGYPRFRSPEE
ECCCHHCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCEECCCCCCCCCCCCCCCHHH
IIPAIKYTGFNVVITANNHSLDNLEFGVVNTLNALDKYGLFHAGTYRNEEESKKILIIDK
HHCCEEECCEEEEEEECCCCCCCEEEHHHHHHHHHHHCCCEECCCCCCCCCCCEEEEEEC
KGIKVAILAYTFGTNGMEVHIDRGKLKYMVNYIEEEKILKDINRAKEEGADIVILYLHWG
CCCEEEEEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
MEYARTVDEERKTLTDKLFRAGADIILGTHPHVIQPMEKKKITTDEGEEKEVFVAYSLGN
HHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHCCCHHHCCCCCCCCCCCEEEEEEEHHH
FISNQRDRYQDSGVIVNITITKKNDKTSITEVSYVPTWVRVFKKEGKTQYRILPVGKFLN
HHCCHHHHHCCCCEEEEEEEEECCCCCCEEEEEHHHHHHHHHHHCCCCEEEEEECCCCCC
CEELSSTELERIREVWQETTDIVGSDGIKIKD
HHHCCHHHHHHHHHHHHHHHHHCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2536679; 10475962; 12004073 [H]