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The map label for this gene is aroF [H]

Identifier: 167040493

GI number: 167040493

Start: 1877827

End: 1878609

Strand: Reverse

Name: aroF [H]

Synonym: Teth514_1862

Alternate gene names: 167040493

Gene position: 1878609-1877827 (Counterclockwise)

Preceding gene: 167040494

Following gene: 167040492

Centisome position: 76.45

GC content: 36.14

Gene sequence:

>783_bases
ATGGACCTTAAAATAATTGGCGACAAAAATAATAAAATATCAATAAAAATAGGAGATATAACTGTTGGAAAAGATAAACT
AATAATAGCGGGACCTTGTGCTATAGAGAATGAAGAAATGCTAGTAAAAACAGCAGAAAAAGTTAAAAGCTGTGGCGCAA
ATGCTTTAAGAGGAGGAGCTTATAAGCCCCGCACCTCCCCTTATTCTTTTCAAGGTTTAGGGATTGATGGACTTAAAATG
CTTAAGAATGTGGGAGATATGTTTAATTTGCCAGTTGTAACTGAAGTTTTAGATGTGAGAGATGTTGAAATTGTGGAAAG
ATATGTTGATGTTCTTCAAATAGGTTCAAGAAATATGCAGAATTTTTCGCTTCTCAAAGAAGTAGGAAAAACCAAAAAGC
CTGTTTTGTTAAAAAGGGGATTTTCAGCTACCTATGAAGAATGGCTTTATGCAGCGGAATATATTGCAGTTGAAGGAAAC
ACCAACATCATCATGTGTGAAAGAGGTATAAGGACTTTTGAAACTTATACACGAAATACGCTGGATATTGCTGCAATTTC
AGTAATTCATGAACTTTCAAACTTGCCTATTATCGCAGATGTAAGCCATGGTACAGGGAAAAGAAGCTTAATCATACCGA
TGGCAAAAGCTTCAATAGCTGCTGGCGCAGACGGAATAATGGTGGAAGTTCACCCTGAGCCCGATAAAGCTTTATCTGAT
GGAGAACAGTCTCTTGATTTTTCCCAATTTGAAGAATTGATGAGAGAGATAAAAAGCTATTGA

Upstream 100 bases:

>100_bases
TTGTAGAAAGAATTGCTAAAGGGTATAATAAATCTGAAATGCTGCAGGAAGTTAAGAGTTTTGTATCCAGCTTAAAAGAA
GTGTTATGAAGGTGATGAAA

Downstream 100 bases:

>100_bases
AATTTTGCGTGAGAAAATATATAATAGAAGTAACAGAAAATAATTATCTAAAGAAAATAATTTTAGAAAGTAGGGATAGC
ATGGTAGAGCTAAATAAAAA

Product: 3-deoxy-7-phosphoheptulonate synthase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MDLKIIGDKNNKISIKIGDITVGKDKLIIAGPCAIENEEMLVKTAEKVKSCGANALRGGAYKPRTSPYSFQGLGIDGLKM
LKNVGDMFNLPVVTEVLDVRDVEIVERYVDVLQIGSRNMQNFSLLKEVGKTKKPVLLKRGFSATYEEWLYAAEYIAVEGN
TNIIMCERGIRTFETYTRNTLDIAAISVIHELSNLPIIADVSHGTGKRSLIIPMAKASIAAGADGIMVEVHPEPDKALSD
GEQSLDFSQFEELMREIKSY

Sequences:

>Translated_260_residues
MDLKIIGDKNNKISIKIGDITVGKDKLIIAGPCAIENEEMLVKTAEKVKSCGANALRGGAYKPRTSPYSFQGLGIDGLKM
LKNVGDMFNLPVVTEVLDVRDVEIVERYVDVLQIGSRNMQNFSLLKEVGKTKKPVLLKRGFSATYEEWLYAAEYIAVEGN
TNIIMCERGIRTFETYTRNTLDIAAISVIHELSNLPIIADVSHGTGKRSLIIPMAKASIAAGADGIMVEVHPEPDKALSD
GEQSLDFSQFEELMREIKSY
>Mature_260_residues
MDLKIIGDKNNKISIKIGDITVGKDKLIIAGPCAIENEEMLVKTAEKVKSCGANALRGGAYKPRTSPYSFQGLGIDGLKM
LKNVGDMFNLPVVTEVLDVRDVEIVERYVDVLQIGSRNMQNFSLLKEVGKTKKPVLLKRGFSATYEEWLYAAEYIAVEGN
TNIIMCERGIRTFETYTRNTLDIAAISVIHELSNLPIIADVSHGTGKRSLIIPMAKASIAAGADGIMVEVHPEPDKALSD
GEQSLDFSQFEELMREIKSY

Specific function: Catalyzes the condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG2876

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=266, Percent_Identity=23.3082706766917, Blast_Score=89, Evalue=2e-19,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006268 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 28644; Mature: 28644

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLKIIGDKNNKISIKIGDITVGKDKLIIAGPCAIENEEMLVKTAEKVKSCGANALRGGA
CCEEEEECCCCEEEEEECCEEECCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCHHCCCC
YKPRTSPYSFQGLGIDGLKMLKNVGDMFNLPVVTEVLDVRDVEIVERYVDVLQIGSRNMQ
CCCCCCCCCEECCCHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCCH
NFSLLKEVGKTKKPVLLKRGFSATYEEWLYAAEYIAVEGNTNIIMCERGIRTFETYTRNT
HHHHHHHHCCCCCCEEEECCCCHHHHHHHHEEEEEEEECCCCEEEECCCCHHHHHHCCCC
LDIAAISVIHELSNLPIIADVSHGTGKRSLIIPMAKASIAAGADGIMVEVHPEPDKALSD
HHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEHHHHHHCCCCCEEEEECCCCCHHHCC
GEQSLDFSQFEELMREIKSY
CHHCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MDLKIIGDKNNKISIKIGDITVGKDKLIIAGPCAIENEEMLVKTAEKVKSCGANALRGGA
CCEEEEECCCCEEEEEECCEEECCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCHHCCCC
YKPRTSPYSFQGLGIDGLKMLKNVGDMFNLPVVTEVLDVRDVEIVERYVDVLQIGSRNMQ
CCCCCCCCCEECCCHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCCH
NFSLLKEVGKTKKPVLLKRGFSATYEEWLYAAEYIAVEGNTNIIMCERGIRTFETYTRNT
HHHHHHHHCCCCCCEEEECCCCHHHHHHHHEEEEEEEECCCCEEEECCCCHHHHHHCCCC
LDIAAISVIHELSNLPIIADVSHGTGKRSLIIPMAKASIAAGADGIMVEVHPEPDKALSD
HHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEHHHHHHCCCCCEEEEECCCCCHHHCC
GEQSLDFSQFEELMREIKSY
CHHCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571; 12743122 [H]