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The map label for this gene is appC [H]

Identifier: 167040430

GI number: 167040430

Start: 1803938

End: 1804819

Strand: Reverse

Name: appC [H]

Synonym: Teth514_1794

Alternate gene names: 167040430

Gene position: 1804819-1803938 (Counterclockwise)

Preceding gene: 167040431

Following gene: 167040429

Centisome position: 73.45

GC content: 31.41

Gene sequence:

>882_bases
ATGAAAAAAGAAAATATTGCAAACTTTTATTATGATTACATTCAGCCTTTATTAACAAATAAAAAATCTTTAATTGGGTT
AATGATATTGCTATTTTATATATTGATGGCTACAATAGGTCCTGTTGTAGTACCTTTAGATATGAATTCTAACTTTGCAG
AAAGGTATCAAAAACCTTCTTTGAAACATCCTTTTGGGACAGACTATTTTGGAGTAGATATTTTCCAACAAATTGTACAC
GGTTCTAGGTCTGTTATTTCTCTTACTTTATTAGCAAGTTTTTTTGCTGTGCTAATAGGAACGGTTATTGGTGTTGCAAG
AGGGTATTTAGAAGGGATTGCTGGTAAAATCATTGATGCTATTATTATGGTTTTTCTAGTAATTCCGTCATTTCCTGCTC
TATTGATTCTAGCTGCTATATTTGTTAATTACAACCTTAATGTTGTTGAAATAGCTCTATTAGTTTCTATATGGTTATGG
GCACCATTGGCGAAACAAATATCAGCTCAGGTTTTATCTATTAAATCAAAAGAATTCATAGAAGCGTCAAAAATGCTTAA
TATGCCGCTTAGTTATATTTTATTCAGTGATATTGCAAAACTTTTAATTCCTTATATTTTCATAAATTTTGTCATGCAGA
TAAAAGGAGCTATGGAGTTTTCAGTAGGACTTATGTTTTTAGGACTAGCCAAGTTTGATCCTACCCATTGGGGAATCATG
TTAAATTATGCTTTATACCAAGCGGGAGCCTTGTATACTGCTAAAGGGTTTCACTATTTATTCTTTATAATTTTAAATAT
AGTATTACTAATTTACGGCGGAATATTGTTATCACAAGGGGTTGAAGAAGTTTTCAACCCACGGCTTAGGGGGAATGAAT
AA

Upstream 100 bases:

>100_bases
TATTGACTGGATTGTTTACTCTAATTGTAATAGGAGTAATATTAGCAACTTTTATTGCAGATTTTGTTTATGCATTAATT
GATCCGAGGGTGAAATTGAA

Downstream 100 bases:

>100_bases
GTTGAATCCAATAATAAAAGTAGAAAATTTAAAAGCAGTATATCTTGTGAGAGAAGGTACGATTAAAGCAGCAGACGGTA
TTTCTTTTGAGGTTCCAGAA

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MKKENIANFYYDYIQPLLTNKKSLIGLMILLFYILMATIGPVVVPLDMNSNFAERYQKPSLKHPFGTDYFGVDIFQQIVH
GSRSVISLTLLASFFAVLIGTVIGVARGYLEGIAGKIIDAIIMVFLVIPSFPALLILAAIFVNYNLNVVEIALLVSIWLW
APLAKQISAQVLSIKSKEFIEASKMLNMPLSYILFSDIAKLLIPYIFINFVMQIKGAMEFSVGLMFLGLAKFDPTHWGIM
LNYALYQAGALYTAKGFHYLFFIILNIVLLIYGGILLSQGVEEVFNPRLRGNE

Sequences:

>Translated_293_residues
MKKENIANFYYDYIQPLLTNKKSLIGLMILLFYILMATIGPVVVPLDMNSNFAERYQKPSLKHPFGTDYFGVDIFQQIVH
GSRSVISLTLLASFFAVLIGTVIGVARGYLEGIAGKIIDAIIMVFLVIPSFPALLILAAIFVNYNLNVVEIALLVSIWLW
APLAKQISAQVLSIKSKEFIEASKMLNMPLSYILFSDIAKLLIPYIFINFVMQIKGAMEFSVGLMFLGLAKFDPTHWGIM
LNYALYQAGALYTAKGFHYLFFIILNIVLLIYGGILLSQGVEEVFNPRLRGNE
>Mature_293_residues
MKKENIANFYYDYIQPLLTNKKSLIGLMILLFYILMATIGPVVVPLDMNSNFAERYQKPSLKHPFGTDYFGVDIFQQIVH
GSRSVISLTLLASFFAVLIGTVIGVARGYLEGIAGKIIDAIIMVFLVIPSFPALLILAAIFVNYNLNVVEIALLVSIWLW
APLAKQISAQVLSIKSKEFIEASKMLNMPLSYILFSDIAKLLIPYIFINFVMQIKGAMEFSVGLMFLGLAKFDPTHWGIM
LNYALYQAGALYTAKGFHYLFFIILNIVLLIYGGILLSQGVEEVFNPRLRGNE

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=294, Percent_Identity=24.4897959183673, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1787760, Length=272, Percent_Identity=26.8382352941176, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789889, Length=199, Percent_Identity=26.6331658291457, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787498, Length=299, Percent_Identity=24.4147157190635, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32843; Mature: 32843

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]