BacMap

Definition	Thermoanaerobacter sp. X514 chromosome, complete genome.
Accession	NC_010320
Length	2,457,259

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The map label for this gene is fabG [C]

Identifier: 167040419

GI number: 167040419

Start: 1792496

End: 1793263

Strand: Reverse

Name: fabG [C]

Synonym: Teth514_1783

Alternate gene names: 167040419

Gene position: 1793263-1792496 (Counterclockwise)

Preceding gene: 167040420

Following gene: 167040418

Centisome position: 72.98

GC content: 37.63

Gene sequence:

>768_bases
ATGGATTTTAATGACAAAGTAGTGATAGTTACAGGTGGAGGACAAGGAATAGGCCGGTGTATTGCGCAAACTTTTGCTGA
AAAAGGAGCAAAAGTAGTTATAGCCGATATTGACGATGAGGCTGGCATAGAAAATGAAAAATATATAAAATCTAAAGGTG
GAGATTGTCTTTTTGTACATACAGATGTTTCTTTAGAGGAAGATGTTAGGAATTTGGTAGATAAGACGATAAAAACCTAT
GGTAAGATCGATATTTTGATAAACAATGCAGGTATTGGGTCAGGAGGGACGATTTACACAAGGCCCATGGAGGAATGGGA
TAGAGTCATAAATGTGAATTTAAGAGGAACATATATGTGTTCAAAATATGTTGCTCCTCACATGAGAGACAATGGCGGAG
GAGTCATAATAAATATAGCGTCTACAAGGGCATTTATGTCAGAACCTCATACAGAACCTTATTCTGCTTCAAAAGGTGGT
ATTATAGCTTTAACTCACTCTCTTGCAATAAGTTTAAGTTATGATAAAATAAGGGTGAATTCTATAAGTCCCGGATGGAT
AGAAGTGTCTGAATGGAAGAAAAGTAGAGAAGCTAAAAAGCCCCAATTGACAGAAGAGGACCATTTGCAACATCCTGCAG
GACGGGTGGGTAAACCAGAGGACGTAGCAAATGCATGTTTATTTTTGTGTTCGGAAGAAGCTTCTTTTATTACAGGAGCG
AATCTCATTGTGGATGGCGGAATGACAGTTAAAATGATATATGTTTGA

Upstream 100 bases:

>100_bases
AAACTTTTAAGTTATACTATTTTTGATAAGGTATACCTCTTTTTTTTACTATGGGGTTACCTTATCTTCTTTTATAAGTT
AAGAGATTGGAGGGTTAACT

Downstream 100 bases:

>100_bases
TTTTAAATATTCTTCTTTTGTTAAAAATATTTAACAAGATAAACTTTCCCAATAAAGTTGTTTCCTAAGTTTTTCAACGC
AATAAATCCTTATCTGCCTA

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: 3alpha12alpha-dihydroxy-oxobeta-cholanate; NADH [C]

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MDFNDKVVIVTGGGQGIGRCIAQTFAEKGAKVVIADIDDEAGIENEKYIKSKGGDCLFVHTDVSLEEDVRNLVDKTIKTY
GKIDILINNAGIGSGGTIYTRPMEEWDRVINVNLRGTYMCSKYVAPHMRDNGGGVIINIASTRAFMSEPHTEPYSASKGG
IIALTHSLAISLSYDKIRVNSISPGWIEVSEWKKSREAKKPQLTEEDHLQHPAGRVGKPEDVANACLFLCSEEASFITGA
NLIVDGGMTVKMIYV

Sequences:

>Translated_255_residues
MDFNDKVVIVTGGGQGIGRCIAQTFAEKGAKVVIADIDDEAGIENEKYIKSKGGDCLFVHTDVSLEEDVRNLVDKTIKTY
GKIDILINNAGIGSGGTIYTRPMEEWDRVINVNLRGTYMCSKYVAPHMRDNGGGVIINIASTRAFMSEPHTEPYSASKGG
IIALTHSLAISLSYDKIRVNSISPGWIEVSEWKKSREAKKPQLTEEDHLQHPAGRVGKPEDVANACLFLCSEEASFITGA
NLIVDGGMTVKMIYV
>Mature_255_residues
MDFNDKVVIVTGGGQGIGRCIAQTFAEKGAKVVIADIDDEAGIENEKYIKSKGGDCLFVHTDVSLEEDVRNLVDKTIKTY
GKIDILINNAGIGSGGTIYTRPMEEWDRVINVNLRGTYMCSKYVAPHMRDNGGGVIINIASTRAFMSEPHTEPYSASKGG
IIALTHSLAISLSYDKIRVNSISPGWIEVSEWKKSREAKKPQLTEEDHLQHPAGRVGKPEDVANACLFLCSEEASFITGA
NLIVDGGMTVKMIYV

Specific function: 7-Alpha-Dehydroxylation Of Cholic Acid, Yielding Deoxycholic Acid And Lithocholic Acid, Respectively. Highest Affinity With Taurochenodeoxycholic Acid. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=251, Percent_Identity=33.4661354581673, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI59889578, Length=231, Percent_Identity=36.7965367965368, Blast_Score=135, Evalue=3e-32,
Organism=Homo sapiens, GI40254992, Length=248, Percent_Identity=33.4677419354839, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI19923817, Length=259, Percent_Identity=33.2046332046332, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI15277342, Length=255, Percent_Identity=32.156862745098, Blast_Score=125, Evalue=4e-29,
Organism=Homo sapiens, GI126723750, Length=254, Percent_Identity=31.8897637795276, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI31542939, Length=251, Percent_Identity=32.2709163346614, Blast_Score=118, Evalue=4e-27,
Organism=Homo sapiens, GI4758504, Length=257, Percent_Identity=32.295719844358, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI10190704, Length=250, Percent_Identity=32, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI5031737, Length=246, Percent_Identity=30.8943089430894, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI66933014, Length=248, Percent_Identity=31.0483870967742, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI83715985, Length=179, Percent_Identity=35.7541899441341, Blast_Score=104, Evalue=7e-23,
Organism=Homo sapiens, GI224922801, Length=180, Percent_Identity=35, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI4504505, Length=241, Percent_Identity=30.7053941908714, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI126723191, Length=181, Percent_Identity=30.939226519337, Blast_Score=98, Evalue=6e-21,
Organism=Homo sapiens, GI7705925, Length=246, Percent_Identity=29.2682926829268, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI209862901, Length=220, Percent_Identity=32.2727272727273, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI19923983, Length=220, Percent_Identity=32.2727272727273, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI109715829, Length=250, Percent_Identity=30, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI33667109, Length=188, Percent_Identity=29.7872340425532, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI142976729, Length=209, Percent_Identity=27.7511961722488, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI40807363, Length=187, Percent_Identity=29.4117647058824, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI25282469, Length=223, Percent_Identity=26.457399103139, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI40254986, Length=140, Percent_Identity=35, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI4503301, Length=258, Percent_Identity=29.8449612403101, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI302344755, Length=107, Percent_Identity=34.5794392523364, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI20149619, Length=192, Percent_Identity=28.6458333333333, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI310128830, Length=197, Percent_Identity=28.9340101522843, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI310115468, Length=197, Percent_Identity=28.9340101522843, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI210032110, Length=168, Percent_Identity=26.1904761904762, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4503817, Length=221, Percent_Identity=24.8868778280543, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI7706318, Length=192, Percent_Identity=27.0833333333333, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1787905, Length=248, Percent_Identity=39.1129032258064, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI1787335, Length=248, Percent_Identity=34.2741935483871, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1790717, Length=247, Percent_Identity=32.3886639676113, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=31.8897637795276, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1789208, Length=247, Percent_Identity=30.3643724696356, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI87082160, Length=254, Percent_Identity=30.3149606299213, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1788459, Length=247, Percent_Identity=31.1740890688259, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786812, Length=256, Percent_Identity=30.46875, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1789057, Length=257, Percent_Identity=29.1828793774319, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI2367175, Length=247, Percent_Identity=31.1740890688259, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI1789378, Length=250, Percent_Identity=28.8, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI2367365, Length=247, Percent_Identity=30.7692307692308, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787820, Length=230, Percent_Identity=27.8260869565217, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1787526, Length=249, Percent_Identity=22.4899598393574, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17561402, Length=256, Percent_Identity=35.546875, Blast_Score=149, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI25147288, Length=247, Percent_Identity=35.6275303643725, Blast_Score=138, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17555706, Length=248, Percent_Identity=33.4677419354839, Blast_Score=128, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17559104, Length=264, Percent_Identity=33.7121212121212, Blast_Score=123, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=32.3886639676113, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71994600, Length=247, Percent_Identity=31.9838056680162, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17562904, Length=269, Percent_Identity=32.7137546468402, Blast_Score=121, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17560676, Length=253, Percent_Identity=29.6442687747036, Blast_Score=120, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI17536651, Length=252, Percent_Identity=33.7301587301587, Blast_Score=118, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17562910, Length=265, Percent_Identity=34.7169811320755, Blast_Score=118, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17562906, Length=267, Percent_Identity=31.0861423220974, Blast_Score=117, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17560332, Length=268, Percent_Identity=32.4626865671642, Blast_Score=116, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI17562908, Length=273, Percent_Identity=30.7692307692308, Blast_Score=114, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17551412, Length=263, Percent_Identity=30.7984790874525, Blast_Score=114, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI193204405, Length=267, Percent_Identity=29.9625468164794, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17560220, Length=263, Percent_Identity=30.4182509505703, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI115534694, Length=251, Percent_Identity=33.0677290836653, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17565030, Length=263, Percent_Identity=33.0798479087452, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17536025, Length=246, Percent_Identity=32.9268292682927, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17538182, Length=254, Percent_Identity=31.496062992126, Blast_Score=107, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17538486, Length=263, Percent_Identity=31.5589353612167, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17531453, Length=269, Percent_Identity=29.7397769516729, Blast_Score=104, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17538480, Length=269, Percent_Identity=28.6245353159851, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17560150, Length=266, Percent_Identity=30.0751879699248, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17544670, Length=265, Percent_Identity=29.811320754717, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI72000259, Length=263, Percent_Identity=30.4182509505703, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17563726, Length=260, Percent_Identity=29.6153846153846, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17562990, Length=270, Percent_Identity=29.2592592592593, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17564282, Length=190, Percent_Identity=32.6315789473684, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17568967, Length=193, Percent_Identity=31.6062176165803, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI193203115, Length=188, Percent_Identity=29.7872340425532, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI193203117, Length=184, Percent_Identity=29.8913043478261, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17508651, Length=253, Percent_Identity=29.2490118577075, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17508895, Length=202, Percent_Identity=25.2475247524752, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17567345, Length=167, Percent_Identity=30.5389221556886, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17561272, Length=257, Percent_Identity=31.5175097276265, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI86565303, Length=204, Percent_Identity=31.8627450980392, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71982365, Length=259, Percent_Identity=27.027027027027, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71997099, Length=204, Percent_Identity=29.9019607843137, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17555612, Length=203, Percent_Identity=30.0492610837438, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322861, Length=241, Percent_Identity=31.9502074688797, Blast_Score=105, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6324126, Length=250, Percent_Identity=30.4, Blast_Score=102, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6323882, Length=192, Percent_Identity=29.1666666666667, Blast_Score=66, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6320089, Length=195, Percent_Identity=27.1794871794872, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=35.2, Blast_Score=148, Evalue=4e-36,
Organism=Drosophila melanogaster, GI28571526, Length=248, Percent_Identity=34.6774193548387, Blast_Score=143, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=35.2941176470588, Blast_Score=140, Evalue=6e-34,
Organism=Drosophila melanogaster, GI23397609, Length=255, Percent_Identity=35.2941176470588, Blast_Score=139, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24639444, Length=247, Percent_Identity=32.7935222672065, Blast_Score=124, Evalue=4e-29,
Organism=Drosophila melanogaster, GI21355319, Length=254, Percent_Identity=31.8897637795276, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24644337, Length=254, Percent_Identity=32.6771653543307, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI17737361, Length=256, Percent_Identity=29.296875, Blast_Score=107, Evalue=7e-24,
Organism=Drosophila melanogaster, GI18859837, Length=241, Percent_Identity=27.3858921161826, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24643142, Length=262, Percent_Identity=30.5343511450382, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI281364892, Length=188, Percent_Identity=31.3829787234043, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24581726, Length=214, Percent_Identity=32.7102803738318, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI21356301, Length=203, Percent_Identity=30.5418719211823, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21358495, Length=187, Percent_Identity=28.3422459893048, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21357673, Length=189, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24640492, Length=199, Percent_Identity=25.6281407035176, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24649181, Length=192, Percent_Identity=25, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21355631, Length=173, Percent_Identity=28.9017341040462, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI221331218, Length=194, Percent_Identity=29.8969072164948, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24665243, Length=194, Percent_Identity=29.8969072164948, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI221510726, Length=192, Percent_Identity=31.25, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24665247, Length=195, Percent_Identity=30.7692307692308, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI221331216, Length=195, Percent_Identity=30.7692307692308, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI116007236, Length=236, Percent_Identity=28.8135593220339, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28571387, Length=247, Percent_Identity=27.5303643724696, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI116007234, Length=243, Percent_Identity=27.9835390946502, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24641232, Length=238, Percent_Identity=26.890756302521, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45553409, Length=205, Percent_Identity=25.8536585365854, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24647948, Length=205, Percent_Identity=25.8536585365854, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24647946, Length=205, Percent_Identity=25.8536585365854, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.159 [C]

Molecular weight: Translated: 27770; Mature: 27770

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFNDKVVIVTGGGQGIGRCIAQTFAEKGAKVVIADIDDEAGIENEKYIKSKGGDCLFVH
CCCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHCCCCCEEEEE
TDVSLEEDVRNLVDKTIKTYGKIDILINNAGIGSGGTIYTRPMEEWDRVINVNLRGTYMC
ECCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCEEEECCHHHHCCEEEEEECEEEEE
SKYVAPHMRDNGGGVIINIASTRAFMSEPHTEPYSASKGGIIALTHSLAISLSYDKIRVN
HHHCCCCEECCCCEEEEEEECCHHHHCCCCCCCCCCCCCCEEEEEEEEEEEEEECEEEEE
SISPGWIEVSEWKKSREAKKPQLTEEDHLQHPAGRVGKPEDVANACLFLCSEEASFITGA
CCCCCEEEHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHEEECCCCCEEECC
NLIVDGGMTVKMIYV
EEEEECCCEEEEEEC
>Mature Secondary Structure
MDFNDKVVIVTGGGQGIGRCIAQTFAEKGAKVVIADIDDEAGIENEKYIKSKGGDCLFVH
CCCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHCCCCCEEEEE
TDVSLEEDVRNLVDKTIKTYGKIDILINNAGIGSGGTIYTRPMEEWDRVINVNLRGTYMC
ECCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCEEEECCHHHHCCEEEEEECEEEEE
SKYVAPHMRDNGGGVIINIASTRAFMSEPHTEPYSASKGGIIALTHSLAISLSYDKIRVN
HHHCCCCEECCCCEEEEEEECCHHHHCCCCCCCCCCCCCCEEEEEEEEEEEEEECEEEEE
SISPGWIEVSEWKKSREAKKPQLTEEDHLQHPAGRVGKPEDVANACLFLCSEEASFITGA
CCCCCEEEHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHEEECCCCCEEECC
NLIVDGGMTVKMIYV
EEEEECCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: 2-Mercaptoethanol; Dithiothreitol; NAD+; NADH [C]

Metal ions: CaCl2; KCl; MnCl2; NaCl [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.8 {cholic} 0.085 {glycochenodeoxycholic} 0.24 {taurochenodeoxycholic} 1 {glycocholic} 0.06 {chenodeoxycholic} [C]

Substrates: @ALPH01.txt*3alpha7alpha12alpha-Trihydroxybeta-cholanate!; NAD [C]

Specific reaction: @ALPH01.txt*3alpha7alpha12alpha-Trihydroxybeta-cholanate! + NAD+ = 3alpha12alpha-dihydroxy-oxobeta-cholanate + NADH [C]

General reaction: Redox reaction [C]

Inhibitor: Ascorbicacid; BaCl2; CoCl2; CuCl2; EDTA; FeCl3; HgCl2; MgCl2; NH4Cl; Potassiumoxalate; Sodiumcitrate; Sodiumlaurylsulfate; Sodiumperchlorate; Sodiumperiodate; Sodiumpersulfate; TritonX-100; Tween; ZnCl2 [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8550425; 10360571 [H]