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The map label for this gene is ddl [H]

Identifier: 167040420

GI number: 167040420

Start: 1793510

End: 1794487

Strand: Reverse

Name: ddl [H]

Synonym: Teth514_1784

Alternate gene names: 167040420

Gene position: 1794487-1793510 (Counterclockwise)

Preceding gene: 167040421

Following gene: 167040419

Centisome position: 73.03

GC content: 33.95

Gene sequence:

>978_bases
ATGAAAATTGGTGTGCTTTGGAGGAAATTCAGGAATGTCGAATTTCAGAGGAAATTGACGCCAGACAAAGTATATGACGA
TGCCTATGATGAAGCATACCATCATTATATGGCCATAAAAGAAGCTGGATTTGATTCAGTCCTCATAGAATGGAAGGAAG
ATCCATTAGAAACTTATGAAACTATAAAAAAAGAAAAGGTGGATTTAATTTTTAATACCTCGAGTATGAAAGAAGTAGCA
TTTTTAGAAGTATTCAACATACCATATGTTGGATCTGGTTTGGACGTAGTAGCAACTGATAAGAGAATGAGGAAGGACAT
TGTGGCTTCTCACGGTTTGCCTACGCCTAAATATGTAATTGCAGAAAATCCTCAAGAAATTCCTTCTGTAGACCATCTTA
AATTTCCTCTATTTGTAAAACCTATAAGTGGAAGAGGAAGTGCAGGTATAGATGAAGAAAATATAATTTATGATAAGGAT
AAACTTCCACAAGTTGTAAGCAAAATAACAGAAAAAATAGGACAAGCAGCGCTAATCGAAGAATTCATCGAAGGAAAAGA
AGTGACCGTTGGAATAATCGGATATAAACACCCACAAGTATTGCCTTTATTGGAAGTAGGATATAATAACGTTAAAACTA
ATACTTATGAACACAAAATGTTTGACAACGAGATAATAAAATGCCCTATAGAAGTACCAAAAGAAGTGGAAGAAAAGATT
AAAGAGACGGCTTTGAATATTTATAAGGTTTTAAATGCCAAGGATTTTGCTAGAATTGATATGATTCTAAGCAAAGATAA
TGTTCCTTATTTCTTAGAATTGAATACCTTTGCGGGACTTACAATGTCAAGTAGCAAAGGAGAAAAACATGTTCACCACG
GATACATGGGTTATATGGCAAAAGCGGCAGGTTTAACAAGAGGAGAATTTATTGGGAAGATTATAGAAAGTGCTATAGAA
AGGTATAAATTGAAGTAA

Upstream 100 bases:

>100_bases
TTATAACTGACATGGTGGTGAATCACACAGAAACTGTATTTAAGTAGTTTTTACTTTTCTTTTCAAAAATTTTTATAAAA
ATTGAAAAGGGTGATGCCAT

Downstream 100 bases:

>100_bases
TTTGAGGGGCCAGCCTCCGGCCCCCCCTCCATCTTTTGGTCTTGCTAAGTTTAGGACTGTTCGGTCAAGTTGCGCGCTTT
GTGCAAAATGTCAGCTACCT

Product: D-alanine--D-alanine ligase

Products: NA

Alternate protein names: D-Ala-D-Ala ligase; D-alanylalanine synthetase [H]

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MKIGVLWRKFRNVEFQRKLTPDKVYDDAYDEAYHHYMAIKEAGFDSVLIEWKEDPLETYETIKKEKVDLIFNTSSMKEVA
FLEVFNIPYVGSGLDVVATDKRMRKDIVASHGLPTPKYVIAENPQEIPSVDHLKFPLFVKPISGRGSAGIDEENIIYDKD
KLPQVVSKITEKIGQAALIEEFIEGKEVTVGIIGYKHPQVLPLLEVGYNNVKTNTYEHKMFDNEIIKCPIEVPKEVEEKI
KETALNIYKVLNAKDFARIDMILSKDNVPYFLELNTFAGLTMSSSKGEKHVHHGYMGYMAKAAGLTRGEFIGKIIESAIE
RYKLK

Sequences:

>Translated_325_residues
MKIGVLWRKFRNVEFQRKLTPDKVYDDAYDEAYHHYMAIKEAGFDSVLIEWKEDPLETYETIKKEKVDLIFNTSSMKEVA
FLEVFNIPYVGSGLDVVATDKRMRKDIVASHGLPTPKYVIAENPQEIPSVDHLKFPLFVKPISGRGSAGIDEENIIYDKD
KLPQVVSKITEKIGQAALIEEFIEGKEVTVGIIGYKHPQVLPLLEVGYNNVKTNTYEHKMFDNEIIKCPIEVPKEVEEKI
KETALNIYKVLNAKDFARIDMILSKDNVPYFLELNTFAGLTMSSSKGEKHVHHGYMGYMAKAAGLTRGEFIGKIIESAIE
RYKLK
>Mature_325_residues
MKIGVLWRKFRNVEFQRKLTPDKVYDDAYDEAYHHYMAIKEAGFDSVLIEWKEDPLETYETIKKEKVDLIFNTSSMKEVA
FLEVFNIPYVGSGLDVVATDKRMRKDIVASHGLPTPKYVIAENPQEIPSVDHLKFPLFVKPISGRGSAGIDEENIIYDKD
KLPQVVSKITEKIGQAALIEEFIEGKEVTVGIIGYKHPQVLPLLEVGYNNVKTNTYEHKMFDNEIIKCPIEVPKEVEEKI
KETALNIYKVLNAKDFARIDMILSKDNVPYFLELNTFAGLTMSSSKGEKHVHHGYMGYMAKAAGLTRGEFIGKIIESAIE
RYKLK

Specific function: Cell wall formation [H]

COG id: COG1181

COG function: function code M; D-alanine-D-alanine ligase and related ATP-grasp enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Escherichia coli, GI1786280, Length=298, Percent_Identity=24.496644295302, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1786579, Length=257, Percent_Identity=26.0700389105058, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR000291
- InterPro:   IPR005905
- InterPro:   IPR011095
- InterPro:   IPR011127
- InterPro:   IPR013817
- InterPro:   IPR016185 [H]

Pfam domain/function: PF07478 Dala_Dala_lig_C; PF01820 Dala_Dala_lig_N [H]

EC number: =6.3.2.4 [H]

Molecular weight: Translated: 37085; Mature: 37085

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS50975 ATP_GRASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGVLWRKFRNVEFQRKLTPDKVYDDAYDEAYHHYMAIKEAGFDSVLIEWKEDPLETYE
CCCHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHH
TIKKEKVDLIFNTSSMKEVAFLEVFNIPYVGSGLDVVATDKRMRKDIVASHGLPTPKYVI
HHHHHCEEEEECCCCHHHHHHHHEECCCEECCCCCEEECCHHHHHHHHHHCCCCCCCEEE
AENPQEIPSVDHLKFPLFVKPISGRGSAGIDEENIIYDKDKLPQVVSKITEKIGQAALIE
CCCHHHCCCCCCEECCEEEEECCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHH
EFIEGKEVTVGIIGYKHPQVLPLLEVGYNNVKTNTYEHKMFDNEIIKCPIEVPKEVEEKI
HHHCCCCEEEEEEECCCCCCCHHHHCCCCCCCCCCCHHHHCCCCEEECCCCCCHHHHHHH
KETALNIYKVLNAKDFARIDMILSKDNVPYFLELNTFAGLTMSSSKGEKHVHHGYMGYMA
HHHHHHHHHHHCCCHHHHEEEEEECCCCCEEEEECCCCCEEECCCCCCHHHHHHHHHHHH
KAAGLTRGEFIGKIIESAIERYKLK
HHCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIGVLWRKFRNVEFQRKLTPDKVYDDAYDEAYHHYMAIKEAGFDSVLIEWKEDPLETYE
CCCHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHH
TIKKEKVDLIFNTSSMKEVAFLEVFNIPYVGSGLDVVATDKRMRKDIVASHGLPTPKYVI
HHHHHCEEEEECCCCHHHHHHHHEECCCEECCCCCEEECCHHHHHHHHHHCCCCCCCEEE
AENPQEIPSVDHLKFPLFVKPISGRGSAGIDEENIIYDKDKLPQVVSKITEKIGQAALIE
CCCHHHCCCCCCEECCEEEEECCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHH
EFIEGKEVTVGIIGYKHPQVLPLLEVGYNNVKTNTYEHKMFDNEIIKCPIEVPKEVEEKI
HHHCCCCEEEEEEECCCCCCCHHHHCCCCCCCCCCCHHHHCCCCEEECCCCCCHHHHHHH
KETALNIYKVLNAKDFARIDMILSKDNVPYFLELNTFAGLTMSSSKGEKHVHHGYMGYMA
HHHHHHHHHHHCCCHHHHEEEEEECCCCCEEEEECCCCCEEECCCCCCHHHHHHHHHHHH
KAAGLTRGEFIGKIIESAIERYKLK
HHCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA