Click here to switch to the map view.

The map label for this gene is gluD [H]

Identifier: 167040229

GI number: 167040229

Start: 1608695

End: 1609945

Strand: Direct

Name: gluD [H]

Synonym: Teth514_1591

Alternate gene names: 167040229

Gene position: 1608695-1609945 (Clockwise)

Preceding gene: 167040228

Following gene: 167040230

Centisome position: 65.47

GC content: 36.37

Gene sequence:

>1251_bases
ATGTCAAAAGAGTCATTAAATCCTTTGATTATTGCGCAAAAGCAGATTAAAAATGCTTGTGATTTGCTGGGGGTAGAAGA
ATTTGTTTATGAACTTTTAAAGGAACCTATGCGAGTATTAGAAGTTTCTATTCCTGTACAGATGGATGATGGTACAGTAA
AAGTCTTTAAAGGTTATAGGTCTCAACACAATGACGCATTAGGACCCACAAAAGGAGGAATAAGATTTCATCCTGACGTT
ACATTAGATGAGGTAAAAGCCTTATCCATGTGGATGACATTTAAATGTGGGGTAGTAGGACTTCCTTATGGAGGAGCAAA
AGGTGGAGTAGTGGTAAATCCAAAAGAATTGTCTAACGATGAGTTACAGAGGTTGAGCAGGGGCTATATAAGAGCAATAA
CGAGCATAATAGGTCCTAATAAAGATATACCTGCACCAGATGTAAATACTAACATGCAAATTATGGCCTGGATGGTAGAT
GAATATAACAAAATTGTAGGTTACAACAGCCCGGCTGTTATTACAGGGAAACCTTTAGTATACGGAGGTTCGAAAGGGAG
AACTGCTGCAACAGGGTATGGAGTTGCGTTAATGGCTCGAGAAGCTATAAAACGTTTACAAATGGATTTTAAAAATTGCA
CAGTAACTGTACAAGGTTTTGGAAACGTAGGAAGTCACACTGCTTTAAACCTTCAAAGATTAGGCGCTAAAATTGTAGCA
GTAAGTGATGTGTATGGAGGTATATACAATAAAGATGGAATTGATGTTGAAAAATTAGTAGAGCATGTAAATAAGACGGG
AACAGTGTGCAATTTTGAGGGAACAACCAGTATAACAAATGAAGAGCTTTTAACAATGGAGGTAGACATTTTAGCTTTAG
CAGCTTTAGAAAATCAGATAACTTTTGCAAATGCGCCAGATGTAAAGGCGAAAATAATTTGCGAAGGAGCAAATGGTCCT
ACAACTCCTGAAGCAGATAAGATTTTAGCAGAAAGAGGTGTGTTTGTAGTTCCGGATATTTTAGCTAATTCAGGAGGAGT
AATAGTTTCATATTTTGAATGGGTACAAAATCTCATGAATTATTATTGGACAGAAAAAGAAGTAGAAGAAAGACAGGAGA
TTATGATGGTAAATGCTTTTAACGCTATATATGAATTAGCACAGCAGTACAAAGTTGATATGAGGACAGCAGCTTACATG
ATATCGATTAAACGGGTTTATGAAGCTATGAAAATTAGAGGTTGGTTATAA

Upstream 100 bases:

>100_bases
TAATTATAAAATTTTGAAGGGTTATTAAAAATTTTGTAGAATATATAACATAGAAATCGATTCATTTGCTTCAAAATTTT
AAAATTAGGAGGATAATAAA

Downstream 100 bases:

>100_bases
AGGGTTAGTACAAAATTAGCGTAAACATTACTCTTATAAACTTTACTGCAATTGCAATTACTGTTTGTTTTTTCTTTAAT
GGGCTCTCTTGTTTATGTAA

Product: Glu/Leu/Phe/Val dehydrogenase, C terminal

Products: NA

Alternate protein names: NAD-GDH [H]

Number of amino acids: Translated: 416; Mature: 415

Protein sequence:

>416_residues
MSKESLNPLIIAQKQIKNACDLLGVEEFVYELLKEPMRVLEVSIPVQMDDGTVKVFKGYRSQHNDALGPTKGGIRFHPDV
TLDEVKALSMWMTFKCGVVGLPYGGAKGGVVVNPKELSNDELQRLSRGYIRAITSIIGPNKDIPAPDVNTNMQIMAWMVD
EYNKIVGYNSPAVITGKPLVYGGSKGRTAATGYGVALMAREAIKRLQMDFKNCTVTVQGFGNVGSHTALNLQRLGAKIVA
VSDVYGGIYNKDGIDVEKLVEHVNKTGTVCNFEGTTSITNEELLTMEVDILALAALENQITFANAPDVKAKIICEGANGP
TTPEADKILAERGVFVVPDILANSGGVIVSYFEWVQNLMNYYWTEKEVEERQEIMMVNAFNAIYELAQQYKVDMRTAAYM
ISIKRVYEAMKIRGWL

Sequences:

>Translated_416_residues
MSKESLNPLIIAQKQIKNACDLLGVEEFVYELLKEPMRVLEVSIPVQMDDGTVKVFKGYRSQHNDALGPTKGGIRFHPDV
TLDEVKALSMWMTFKCGVVGLPYGGAKGGVVVNPKELSNDELQRLSRGYIRAITSIIGPNKDIPAPDVNTNMQIMAWMVD
EYNKIVGYNSPAVITGKPLVYGGSKGRTAATGYGVALMAREAIKRLQMDFKNCTVTVQGFGNVGSHTALNLQRLGAKIVA
VSDVYGGIYNKDGIDVEKLVEHVNKTGTVCNFEGTTSITNEELLTMEVDILALAALENQITFANAPDVKAKIICEGANGP
TTPEADKILAERGVFVVPDILANSGGVIVSYFEWVQNLMNYYWTEKEVEERQEIMMVNAFNAIYELAQQYKVDMRTAAYM
ISIKRVYEAMKIRGWL
>Mature_415_residues
SKESLNPLIIAQKQIKNACDLLGVEEFVYELLKEPMRVLEVSIPVQMDDGTVKVFKGYRSQHNDALGPTKGGIRFHPDVT
LDEVKALSMWMTFKCGVVGLPYGGAKGGVVVNPKELSNDELQRLSRGYIRAITSIIGPNKDIPAPDVNTNMQIMAWMVDE
YNKIVGYNSPAVITGKPLVYGGSKGRTAATGYGVALMAREAIKRLQMDFKNCTVTVQGFGNVGSHTALNLQRLGAKIVAV
SDVYGGIYNKDGIDVEKLVEHVNKTGTVCNFEGTTSITNEELLTMEVDILALAALENQITFANAPDVKAKIICEGANGPT
TPEADKILAERGVFVVPDILANSGGVIVSYFEWVQNLMNYYWTEKEVEERQEIMMVNAFNAIYELAQQYKVDMRTAAYMI
SIKRVYEAMKIRGWL

Specific function: Unknown

COG id: COG0334

COG function: function code E; Glutamate dehydrogenase/leucine dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Glu/Leu/Phe/Val dehydrogenases family [H]

Homologues:

Organism=Homo sapiens, GI31377775, Length=343, Percent_Identity=45.7725947521866, Blast_Score=303, Evalue=1e-82,
Organism=Homo sapiens, GI4885281, Length=343, Percent_Identity=45.4810495626822, Blast_Score=299, Evalue=4e-81,
Organism=Escherichia coli, GI1788059, Length=367, Percent_Identity=32.1525885558583, Blast_Score=191, Evalue=9e-50,
Organism=Caenorhabditis elegans, GI17544676, Length=477, Percent_Identity=36.2683438155136, Blast_Score=275, Evalue=3e-74,
Organism=Saccharomyces cerevisiae, GI6324951, Length=425, Percent_Identity=31.5294117647059, Blast_Score=172, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6319256, Length=401, Percent_Identity=31.6708229426434, Blast_Score=167, Evalue=4e-42,
Organism=Drosophila melanogaster, GI24649283, Length=438, Percent_Identity=38.8127853881278, Blast_Score=285, Evalue=3e-77,
Organism=Drosophila melanogaster, GI45553475, Length=449, Percent_Identity=37.6391982182628, Blast_Score=284, Evalue=7e-77,
Organism=Drosophila melanogaster, GI45549226, Length=341, Percent_Identity=43.6950146627566, Blast_Score=282, Evalue=3e-76,
Organism=Drosophila melanogaster, GI24649460, Length=280, Percent_Identity=43.5714285714286, Blast_Score=225, Evalue=5e-59,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 9362 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006095
- InterPro:   IPR006096
- InterPro:   IPR006097
- InterPro:   IPR014362
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00208 ELFV_dehydrog; PF02812 ELFV_dehydrog_N [H]

EC number: =1.4.1.2 [H]

Molecular weight: Translated: 45885; Mature: 45753

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS00074 GLFV_DEHYDROGENASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKESLNPLIIAQKQIKNACDLLGVEEFVYELLKEPMRVLEVSIPVQMDDGTVKVFKGYR
CCCCCCCCEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHEEEECCEEECCCEEEEHHHHH
SQHNDALGPTKGGIRFHPDVTLDEVKALSMWMTFKCGVVGLPYGGAKGGVVVNPKELSND
HCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHEEECCEEECCCCCCCCCEEECHHHCCHH
ELQRLSRGYIRAITSIIGPNKDIPAPDVNTNMQIMAWMVDEYNKIVGYNSPAVITGKPLV
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHHHCCCCCCEEEECCEEE
YGGSKGRTAATGYGVALMAREAIKRLQMDFKNCTVTVQGFGNVGSHTALNLQRLGAKIVA
ECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHCCCEEEE
VSDVYGGIYNKDGIDVEKLVEHVNKTGTVCNFEGTTSITNEELLTMEVDILALAALENQI
EEHHHCCCCCCCCCCHHHHHHHHCCCCCEEECCCCCCCCCCCEEEEEHHHHHHHHHHCCE
TFANAPDVKAKIICEGANGPTTPEADKILAERGVFVVPDILANSGGVIVSYFEWVQNLMN
EECCCCCCEEEEEEECCCCCCCCHHHHHHHHCCCEEECHHHCCCCCEEEHHHHHHHHHHH
YYWTEKEVEERQEIMMVNAFNAIYELAQQYKVDMRTAAYMISIKRVYEAMKIRGWL
HHCCHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SKESLNPLIIAQKQIKNACDLLGVEEFVYELLKEPMRVLEVSIPVQMDDGTVKVFKGYR
CCCCCCCEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHEEEECCEEECCCEEEEHHHHH
SQHNDALGPTKGGIRFHPDVTLDEVKALSMWMTFKCGVVGLPYGGAKGGVVVNPKELSND
HCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHEEECCEEECCCCCCCCCEEECHHHCCHH
ELQRLSRGYIRAITSIIGPNKDIPAPDVNTNMQIMAWMVDEYNKIVGYNSPAVITGKPLV
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHHHCCCCCCEEEECCEEE
YGGSKGRTAATGYGVALMAREAIKRLQMDFKNCTVTVQGFGNVGSHTALNLQRLGAKIVA
ECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHCCCEEEE
VSDVYGGIYNKDGIDVEKLVEHVNKTGTVCNFEGTTSITNEELLTMEVDILALAALENQI
EEHHHCCCCCCCCCCHHHHHHHHCCCCCEEECCCCCCCCCCCEEEEEHHHHHHHHHHCCE
TFANAPDVKAKIICEGANGPTTPEADKILAERGVFVVPDILANSGGVIVSYFEWVQNLMN
EECCCCCCEEEEEEECCCCCCCCHHHHHHHHCCCEEECHHHCCCCCEEEHHHHHHHHHHH
YYWTEKEVEERQEIMMVNAFNAIYELAQQYKVDMRTAAYMISIKRVYEAMKIRGWL
HHCCHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA